Pharmacokinetics

This page contains news and, when available, background information, on Pharmacokinetics:. Links on this site lead to other sites on the web.


Pharmacokinetics: - The study of the way that drugs move through the body after they are swallowed or injected.
[Environmental Protection Agency]

News archive for Pharmacokinetics::

New HIV Treatment Guidelines Issued  -  04 Aug 2008
Medscape (subscription)...durable, more simple than they were before, and safer, [plus] better formulations with improved pharmacokinetics which enhance adherence and therefore

I-vation Implantable Drug Delivery System for The Eye Enters ...  -  04 Aug 2008
Medgadget.com,The I-vation platform offers a great deal of versatility and flexibility for formulation and pharmacokinetics control. The sustained drug delivery system

Psychotropic Medications Overused Among Foster Children  -  04 Aug 2008
PsychCentral.com,...“So we are generalizing our [knowledge] from adults to children without knowing enough about pharmacokinetics, dosing, or long-term safety in the pediatric

Hollis-Eden Commences Phase I/II Clinical Trial with APOPTONE™ in ...  -  04 Aug 2008
ADMET.net (press release),...pharmacokinetics and potential activity of APOPTONE when administered twice daily for 28 days in up to 44 late-stage prostate cancer patients.

Isotechnika reports presentation of preclinical data demonstrating ...  -  Jul 31, 2008
RTT News,TO: News, Chart, Quote ) announced that its partner, Lux Biosciences, presented preclinical data demonstrating the safety and pharmacokinetics of LX214 as a

Brain and Plasma Pharmacokinetics of Aripiprazole in Patients With ...  -  Aug 1, 2008
Am J Psychiatry (subscription)Gerhard Gründer, MD, Christine Fellows, MD, Hildegard Janouschek, MD, Tanja Veselinovic, MD, Christian Boy, MD, Anno Bröcheler, MD, Katrin M. Kirschbaum,

FDA Clears Path for Acetavance  -  Jul 30, 2008
Wall Street Journal...of acute pain and fever, upon the completion of ongoing clinical trials evaluating pediatric pharmacokinetics, adult safety and pediatric safety.

Cornerstone to Conduct Phase I/II Cancer Trial  -  Jul 30, 2008
FDA news (subscription),The open-label, dose-escalation trial will evaluate safety, tolerability, maximum-tolerated dose, efficacy and pharmacokinetics of the drug in various types

Seattle Genetics Initiates SGN-70 Phase I Clinical Trial  -  Jul 31, 2008
MarketWatchThe trial will assess the safety, tolerability and pharmacokinetics of SGN-70 in healthy volunteers. "CD70 targeted therapies have shown promise in multiple

Momenta Pharmaceuticals Announces Results From a Phase 1 Study of ...  -  Jul 29, 2008
MarketWatchThe poster, titled "Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of M118, a Novel Rationally Engineered Low Molecular Weight Heparin Given as

Theravance Reports Encouraging Results From Phase I COPD Trial  -  Jul 15, 2008
RedOrbit,Theravance has announced the positive results from a Phase I study designed to assess the safety, tolerability and pharmacokinetics of an investigational

Panacos to Present Clinical Data on Bevirimat at the 48th Annual ...  -  Jul 28, 2008
MarketWatch11:15 am - 12:15 pm EST Poster Session #91: HIV Pharmacokinetics/Dynamics -- Pharmacokinetics/Pharmacodynamics of Bevirimat (BVM) in a 14-day Functional

UM receives first batch of PhDs in Chinese Medicine  -  Jul 18, 2008
Macau Daily Times,...quality control and pharmacological activity, while Yu Hua’s thesis titled “Study on the Physiochemical Properties and Pharmacokinetics Profiles of

Simulations Plus and Roche Sign Multi-year Collaboration  -  Jul 28, 2008
MarketWatch...as they have provided invaluable feedback and guidance to the implementation of our PBPK (physiologically based pharmacokinetics) capability in

Rib-X Initiates Phase II Skin Infection Trial  -  Jul 16, 2008
RedOrbit,Part one of the study was designed to compare the safety and pharmacokinetics of the two IV formulations, with the purpose of optimizing the formulation of

Anadys Pharmaceuticals Inc. Q2 2008 Earnings Call Transcript  -  Jul 30, 2008
Seeking Alpha,This trial was designed to evaluate safety in pharmacokinetics and healthy volunteers, and is nearing completion. Based on preclinical PK data, the protocol

Arena Pharma reveals positive results from Phase 1b clinical trial ...  -  Jul 9, 2008
RTT News,In addition to evaluating APD791's safety and tolerability profile, the trial evaluated the pharmacokinetics and pharmacodynamics of multiple oral doses of

Summer school on development and assessment of statistical ...  -  Jul 23, 2008
Cordis News,...industry, and non-governmental organisations) and disciplines (geophysics, land and water management, pharmacokinetics, climate modelling, energy,

Pain Drug Successful in Phase I Trial  -  Jul 22, 2008
FDA news (subscription),The trial tested the safety, tolerability and pharmacokinetics of an oral formulation of the drug in 10 healthy male volunteers. No serious adverse events

Anesiva Begins Phase II Adlea Trial  -  Jul 22, 2008
FDA news (subscription),The multicenter, randomized, double-blind, dose-escalating, placebo-controlled study is evaluating the safety, tolerability, efficacy and pharmacokinetics

Pharming Announces First Half 2008 Results  -  Jul 17, 2008
MarketWatchIn April, Pharming announced that its wholly owned subsidiary DNage started a Phase I clinical study to evaluate the pharmacokinetics and tolerability of

Arena reports encouraging results from Phase Ib thrombosis trial  -  Jul 10, 2008
Trading Markets (press release),In addition to evaluating APD791's safety and tolerability profile, the trial evaluated the pharmacokinetics and pharmacodynamics of multiple oral doses of

XOMA 052 Phase 1 Data to be Presented At European Association for ...  -  Jul 15, 2008
MarketWatchThe two randomized, placebo-controlled, double-blind Phase 1 studies of XOMA 052 in Type 2 diabetes were designed to assess safety and pharmacokinetics,

Arena Sees Positive Results From Arterial Thrombosis Trial  -  Jul 15, 2008
FDA news (subscription),The drug was generally well tolerated, and positive results were seen in the pharmacokinetics and pharmacodynamics of the drug over one week,

Pharmacogenomics and Drug Toxicity  -  Jul 23, 2008
New England Journal of Medicine (subscription),2 Genes in the first two categories influence the pharmacokinetics and pharmacodynamics of drugs. Poor clearance of drugs from the body can increase the

Ore Pharmaceuticals Reports Second Quarter 2008 Financial Results  -  Aug 1, 2008
MarketWatchDeveloped plans to initiate a multiple ascending dose clinical trial of GL1001 later in 2008 to assess its tolerability, pharmacokinetics,

OrthoLogic Initiates Dosing Of Second AZX100 Phase 1 Trial - Quick ...  -  Jul 9, 2008
RTT News,The primary objectives are to evaluate safety and tolerability and to determine preliminary pharmacokinetics of AZX100 in healthy adult subjects undergoing

Understanding prescription drug misuse in older adults  -  Jul 30, 2008
ScienceBlog.com,It has been documented that older patients often self diagnose and misunderstand the label warnings; and the pharmacokinetics associated with the

Sharing the Enlightenment  -  Jul 11, 2008
Corante,...predictive toxicology and pharmacokinetics, clinical biomarkers, new models of disease, delivery methods for protein- and nucleic acid-based therapies,

Research Scientist  -  Jul 10, 2008
HTScreening (press release),The Company has a wealth of experience in molecular biology, bioanalysis and drug metabolism and pharmacokinetics, and has a proven track record in

Xceleron and Industry Experts to Present at CPT 2008 Symposium  -  Jul 29, 2008
PharmaLive.com (press release),Human microdosing provided estimates of clinical pharmacokinetics of four structurally-related compounds, which were deemed useful for compound selection.

Vertex Pharmaceuticals Highlights Telaprevir Progress and Reports ...  -  Jul 31, 2008
MarketWatchThe first trial is a single and multiple dose study while the second is a single dose study examining the pharmacokinetics (PK) and safety of a solid dosage

Theravance Announces Clinical Results in the LAMA Respiratory ...  -  Jul 14, 2008
MarketWatch...today announced the results from a Phase 1 study designed to assess the safety, tolerability and pharmacokinetics of an investigational inhaled long-acting

Peptimmune Announces Grant of United States Patent for PI-2301 ...  -  Jul 30, 2008
MarketWatch...evidence of immune exposure consistent with the pharmacologic mechanism of action for PI-2301, and dose-dependent pharmacokinetics was observed.

Infinity Initiates Clinical Development of IPI-493, Its Oral Anti ...  -  Jul 30, 2008
MarketWatchPharmacokinetics parameters, biologic activity, and effects of IPI-493 on pharmacodynamic markers of biological activity will also be assessed.

Pharming Announces First Half 2008 Results  -  Jul 17, 2008
Ad-Hoc-News (Pressemitteilung),In April, Pharming announced that its wholly owned subsidiary DNagestarted a Phase I clinical study to evaluate the pharmacokinetics andtolerability of

Icagen Successfully Completes Phase I Multiple Ascending Dose ...  -  Jul 9, 2008
FOXBusinessThe multiple ascending dose study was designed to assess the safety, tolerability and pharmacokinetics of senicapoc in healthy volunteers at doses higher

Rib-X Pharmaceuticals Initiates Phase 2 Trial For RX-3341 In ...  -  Jul 16, 2008
Medical News Today (press release),Part 1 of the study was designed to compare the safety and pharmacokinetics of the two IV formulations, with the purpose of optimizing the formulation of

Preclinical Data for a Topical Formulation of Voclosporin as a ...  -  Aug 1, 2008
PharmaLive.com (press release),...data demonstrating the safety and pharmacokinetics of LX214 as a potential once-daily topical treatment for chronic inflammatory diseases of the eye.

Optimizing Pain Control With Fentanyl Patches  -  Jul 15, 2008
Medscape (subscription)A: The pharmacokinetics of FTP shows broad interpatient and intrapatient variability. Elimination of fentanyl after discontinuation is slow,

Momenta Pharmaceuticals Announces Results from M118 Drug-Drug ...  -  Jul 28, 2008
MarketWatch...the impact of multiple doses of ASA and clopidogrel on the pharmacokinetics (PK) and pharmacodynamics (PD) of an IV injection of M118 and the impact of

Stem Cell Therapeutics Corp. to Present Published Data at the IXth ...  -  Jul 28, 2008
FOXBusinessConsequently, it was concluded that these two drugs demonstrate similar pharmacokinetics with respect to the CSF. This study used two separate groups of six

Infinity initiates Phase I study of tumor drug  -  Aug 1, 2008
Trading Markets (press release),Pharmacokinetics parameters, biologic activity, and effects of IPI-493 on pharmacodynamic markers of biological activity will also be assessed.

Hollis-Eden initiates Phase I/II prostate cancer trial  -  Aug 1, 2008
Trading Markets (press release),...pharmacokinetics and potential activity of Apoptone when administered twice daily for 28 days in up to 44 late-stage prostate cancer patients.

Neuropathic Pain - NSL-043 Achieves Success In Phase I Multiple ...  -  Jul 23, 2008
Medical News Today (press release),This trial is the second of two Phase I trials, designed to test the safety, tolerability and pharmacokinetics of an oral formulation of NSL-043 for the

Other News To Note  -  Jul 31, 2008
TMCnetLux Biosciences Inc., of Jersey City, NJ, reported preclinical data demonstrating the safety and pharmacokinetics of LX214 as a potential once-daily topical

MIGENIX Reports Fourth Quarter and Fiscal Year 2008 Financial Results  -  Jul 21, 2008
CNNMoney.com (press release)...pharmacokinetics and viral kinetics when combined with the standard of care drugs (the "PRC" regimen), as compared to the standard of care drugs alone

NSL-043 Achieves Success in Phase I Multiple Ascending Dose Trial  -  Jul 21, 2008
PharmaLive.com (press release),This trial is the second of two Phase I trials, designed to test the safety, tolerability and pharmacokinetics of an oral formulation of NSL-043 for the

ICAD: Monoclonal Antibody that Binds to Amyloid Found Safe in ...  -  Jul 31, 2008
MedPage Today,There was a slight immune response to the antibody in five patients, but it did not affect the pharmacokinetics or binding of beta-amyloid, Dr. Siemers said

EBI, TGen, Johns Hopkins University, NIH, Genomatix, Pfizer ...  -  Jul 18, 2008
bio1nf0rm (subscription),The Ahmedabad lab offers services for small molecule pharmacokinetics, and the UK facility offers biomarker, large molecule pharmacokinetics,




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