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wild type

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wild type - The most frequent allele or genotype found in nature, or a specified organism against which mutants are defined. [FAO]

News archive for wild type.

Progress Understanding Vision Loss Due To Abnormal Network Of ...  -  Aug 18, 2007
Science Daily (press release)...blood vessel development is indistinguishable in wild-type mice and in mice lacking a protein known as sphingosine -1-phosphate receptor 2 (S1P2R).

Full Text  -  Aug 2, 2007
Science Magazine (subscription)...(2) use mass spectrometry to identify quantitative differences in protein levels in daf-2 versus wild-type worms. The changes in protein abundance not only

New tech helps midsize convertibles pass less common safety test  -  Aug 12, 2007
Chicago Tribune,...to the Tribune August 12, 2007 What better way to escape the dog days of summer than with some top-down driving -- no, not the "Girls Gone Wild" type.

Full Text  -  Aug 2, 2007
Science Magazine (subscription)...(B) A fertilized wild-type ovule. The white arrow indicates the site of pollen tube arrest. (C) An unfertilized fer gametophyte. The white arrow indicates

New Oral, Live, Attenuated Human Rotavirus Vaccine Safe and Effective  -  Aug 10, 2007
Medscape (subscription)In this cohort, the predominant serotype of infecting rotavirus was wild-type G1, which was present in 85% of cases. The vaccine was well tolerated overall,

Scientists discover how HIV/AIDS disrupts the normal replication ...  -  Aug 19, 2007
News-Medical.net,...significant decrease in the number of proliferating stem cells in the brains of HIV/gp120-mice compared with similar tissue from normal, wild-type mice.

Clock genes running amok. Clock genes and their role in drug ...  -  Aug 2, 2007
Nature.com (subscription),They repeatedly exposed the flies to volatilized freebase cocaine, which produced, in the wild-type flies, typical sensitized behaviours similar to those

Full Text  -  Aug 16, 2007
Science Magazine (subscription)Conversely, when active SCF is excluded from the primary synapse region (as in the wild-type worms), more SCF is available to "attack" target proteins in

Molecular Evidence for a Link between the N363S Glucocorticoid ...  -  Aug 6, 2007
Journal of Clinical Endocrinology and Metabolism,Design: Functional assays with reporter gene systems, Western blotting, and human microarray analysis were used to evaluate the activity of wild-type and

AIDS Interferes With Stem Cells In The Brain  -  Aug 15, 2007
Science Daily (press release)...significant decrease in the number of proliferating stem cells in the brains of HIV/gp120-mice compared with similar tissue from normal, wild-type mice.

Protein Abundance in Long-lived Mutants  -  Aug 11, 2007
Methuselah Foundation,Of 1685 identifiable proteins, a total of 86 varied markedly between wild type and mutant animals—� 47 were more abundant in daf-2-depleted animals and 39

Full Text  -  Jul 26, 2007
Science Magazine (subscription)QC organization is identical in both wild type and mutants (E6263, E4510) at 2 days. By 4 days after germination, 96% of mutant roots have undergone QC

Medical models: Humanized livers  -  Aug 1, 2007
Nature.com (subscription),Liam Dolan at the John Innes Centre in Norwich, UK, and his colleagues, compared wild-type Arabidopsis thaliana (thale cress) with mutants that had

Were host factors or superinfection the key to case of rapid HIV ...  -  Aug 13, 2007
Aidsmap,Many of the case reports of superinfection have involved the substitution of wild-type, drug-sensitive HIV, with drug-resistant strains of the virus.

Explosive Discovery On Genetically Engineered Tobacco Plant  -  Aug 13, 2007
Science Daily (press release)...can increase the functional and genetic diversity of the bacterial community in acutely polluted soil compared to wild type plants," the report states.

The inexhaustible mouse nose. Focus on "Olfactory epithelia ...  -  Aug 3, 2007
AJP - Cell Physiology (subscription)...(Interestingly, the olfactory epithelium of wild-type mice showed almost no response to amiloride, indicating that ENaC-mediated transport was minimal in

Full Text  -  Aug 2, 2007
Science Magazine (subscription)In a quantitative proteomic study, we identified 86 proteins that were more or less abundant in long-lived daf-2 mutant worms than in wild-type worms.

Meridian Shares Buck The Trend By Actually Rising In Value  -  Aug 10, 2007
CNNMoney.comThe vaccines include non-influenza and influenza products for use in humans, as well as wild-type viruses needed for challenge studies and master cell lines

Elixir Pharmaceuticals to Present Data from Programs to Treat and ...  -  Jul 26, 2007
Business Wire (press release),Additionally, the knockout mice had significantly lower blood glucose, insulin and HbA1c levels compared to normal ('wild-type') mice with the gene.

Epilepsy Diagnosis and Management  -  Aug 16, 2007
Medscape (subscription)...had significantly increased carbamazepine clearance compared with those with CYP3A5*3 homozygous wild type (wt/wt), 42.9 vs 33.8 mL/hour/kg, P = .001.

Memphis lab awarded $12.2M to produce vaccines  -  Aug 7, 2007
Bizjournals.com,The company will also manufacture viruses that have been proven to be promising candidates for use in vaccination of humans and wild type viruses that are

Preclinical Study Links Gene To Brain Aneurysm Formation  -  Aug 7, 2007
Science Daily (press release)The researchers found no indications of aneurysm formation in the PAI-1, NOS-2 or wild type control groups. Mice with the NOS-3 knock out, however,

A Sensory Organ, Not The Brain, Differentiates Male And Female ...  -  Aug 5, 2007
Science Daily (press release)After giving birth, wild-type female mice spend about 80 percent of their time in their nest nursing their newborns, but the mutant females would readily

Full Text  -  Aug 2, 2007
Science Magazine (subscription)In the first trial, they found evidence that an infected person's own "wild-type" HIV could "package" the vector and carry it to uninfected CD4 + cells,

News tips from the Journal of Neuroscience  -  Aug 14, 2007
EurekAlert (press release),Gonadotropin-releasing hormone (GnRH) neurons were activated and released leutinizing hormone after treatment with kisspeptin in wild-type male mice but not

Mechanistic Link Discovered between Calcium Signaling and ...  -  Aug 13, 2007
Newswise (press release)...to identify the role of normal, so-called wild-type presenilin-1 in regulating neuronal function, and to reach the mechanism that drives this function.

Src kinase activity and SH2 domain regulate the dynamics of Src ...  -  Aug 13, 2007
Journal of Cell Biology (subscription)Wild-type Src displays lipid-like membrane association, whereas constitutively active Src-Y527F interacts transiently with slower-diffusing

MicroRNA Works With Ago2 Protein To Regulate Blood Cell Development  -  Jul 26, 2007
Science Daily (press release)O'Carroll then genetically reconstituted the Ago2-deficient stem cells with either wild type Ago2 or a modified version of it that rendered the "slicer"

Scientists Link Longevity With Reduced Insulin-Like Signaling in ...  -  Jul 23, 2007
Medscape (subscription)...compared the lifespan and metabolism of mice with a genetically engineered reduction of insulin sensitivity to that of normal, wild-type mice.

Flocks of phlox bloom in my garden  -  Jul 26, 2007
River Falls Journal (subscription),Numerous cultivars are out there: Loddon Grove, Fuller’s White and May Breeze do well for me, but my favorites are just seedlings from the wild type found

News From The Journal Of Neuroscience  -  Aug 11, 2007
Medical News Today (press release),However, Munc18-1 NV rescued release, albeit to a lesser extent than wild type. Thus, Munc18 regulates a postdocking (priming) step by a mechanism that does

Full Text  -  Aug 9, 2007
Science Magazine (subscription)These variants are non-functional when expressed alone, but make cells resistant to ethidium bromide when coexpressed (10), as does wild-type EmrE.

Earliest evidence of peanut, cotton, squash farming  -  Jul 24, 2007
PhysOrg.com,Dillehay and his colleagues found wild-type peanuts, squash and cotton as well as a quinoa-like grain, manioc and other tubers and fruits in the floors and

Exelixis Announces Second Quarter 2007 Financial Results and ...  -  Aug 7, 2007
Earthtimes.orgXL228 (dual inhibitor of IGF1R and wild-type and mutant forms of ABL including the imatinib and dasatinib resistant T315I mutant form of ABL),

Meridian unit wins $12.2M contract  -  Aug 7, 2007
MSN MoneyThe vaccines include noninfluenza and influenza products for use in humans, as well as wild-type viruses needed for challenge studies and master cell lines

Meridian Bioscience Awarded NIH Contract for Production of ...  -  Aug 7, 2007
Genetic Engineering News (press release),Meridian will also be preparing suspensions of wild type viruses that are needed for challenge studies to evaluate effectiveness of immunoprophylaxis or in

How cells change the pace of their steps  -  Aug 7, 2007
News-Medical.net,...lacked an important cell adhesion protein called Talin, and to their surprise found that cells without Talin moved nearly as fast as wild-type cells.

Arpida Presents a Large Body of Preclinical and Clinical Data at ...  -  Aug 7, 2007
Genetic Engineering News (press release),Repeat Ascending Doses of Iclaprim in Healthy Adults 1545 Murphy Comparative Efficacy of Iclaprim (ICL) against Wild-Type and Thymidine Kinase-Deficient

Methuselah Foundation Announces New Mprize Competitor  -  Aug 6, 2007
Methuselah Foundation,...of fresh food diets, enriched housing and exposure to microbes on the behavioral aspects, life and health spans of wild type mice (Mus musculus).

News From The Journal Of Neuroscience  -  Aug 2, 2007
Medical News Today (press release),Overexpression of wild-type G-substrate protected dopaminergic neurons from 6-hydroxydopamine-induced toxicity. The T123A G-substrate mutant,

Anti-cancer support for omega-3  -  Aug 1, 2007
NutraIngredients.com,The results showed in the transgenic fat-1 mice overall tumor incidence was 87.5 per cent compared to 100 per cent in the wild-type animal.

Cyclin E overexpression impairs progression through mitosis by ...  -  Jul 30, 2007
Journal of Cell Biology (subscription)...used in this paper: APC, anaphase-promoting complex; Cdk, cyclin-dependent kinase; EV, empty vector; IME, immortalized mammary epithelial; WT, wild type.

Scientists Find Gene Expression Pattern Linked to Poor Survival in ...  -  Jul 27, 2007
Genetic Engineering News (press release),In a corroborating study of murine sepsis, MT-null mice demonstrated a survival advantage compared with wild-type mice, report the researchers.

Full Text  -  Jul 26, 2007
Science Magazine (subscription)Wild-type mice injected with the AAV-GUSB vector or a version lacking the Ăź-actin promoter (fig. S1) also developed HCC at significantly higher rates (56%

Full Text  -  Jul 26, 2007
Science Magazine (subscription)...protects against -Syn-induced toxicity in three different paradigms: transfected human H4 neuroglioma cells expressing wild-type -Syn; transfected rat

Avexa Releases ATC Phase IIb Clinical Trial Update  -  Jul 26, 2007
PharmaLive.com (press release),Virus containing this M184V mutation is generally accepted to be replicatively incompetent compared to wild-type HIV, although still able to replicate in

Progenics Presents Additional Positive Clinical Results for HIV ...  -  Jul 26, 2007
PipelineReview.com (press release),Separately, in a poster session at the conference, Progenics also presented in vitro results showing that PRO 140 was active against wild-type HIV as well

Anthropological Discovery Reported In Peru  -  Jul 25, 2007
Post ChronicleDillehay and his colleagues found wild-type peanuts, squash and cotton, as well as a quinoa-like grain, manioc and other tubers and fruits in the floors and

News tips from the Journal of Neuroscience  -  Jul 24, 2007
EurekAlert (press release),After sciatic nerve crush, ATF3 transgenic mice displayed early nerve regeneration similar to wild-type (WT) mice after a preconditioning lesion.

IAS: Regular viral load testing essential for patients in resource ...  -  Jul 24, 2007
Aidsmap,...yet protease inhibitor- resistant virus is associated with lower levels of immune activation when compared to wild-type virus, suggesting that one




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