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receptor - A trans-membrane protein located in the plasma membrane that can bind with a ligand on the extracellular surface, as a result of which it induces a change in activity on the cytoplasmic surface. More generally, a site in a molecule that allows the binding of a ligand. [FAO]

News archive for receptor.

First Animal Model Developed for Oral Infection of Human Poliovirus  -  21 Aug 2007
DentalPlans.com,In the study mice carrying the human poliovirus receptor gene and lacking the interferon receptor gene (IFNAR) were sensitive to an oral challenge of the

Samaritan Licenses Tumor Inhibiting Cancer Drugs That Also ...  -  21 Aug 2007
CNNMoney.com...for a patent covering the Peripheral Benzodiazepine Receptor (PBR) which has led to Cancer drug candidates with the ability to inhibit cancerous tumors;

Discovery of molecule in the intestine that can 'taste' the sugar ...  -  21 Aug 2007
News-Medical.net,Researchers found that the sweet taste receptor that senses sugar and artificial sweeteners is not only present in the tongue, but also in the intestine.

Weizmann Institute Scientists discover: A Survival Mechanism for ...  -  21 Aug 2007
Informationsdienst Wissenschaft (Pressemitteilung),In previous research, Shachar had found that a specific receptor - a protein on the outer surface of healthy B cells - fulfills a crucial role in helping

Discovery of 'sugar sensor' in intestine could benefit diabetes  -  21 Aug 2007
PhysOrg.com,Researchers found that the sweet taste receptor that senses sugar and artificial sweeteners is not only present in the tongue, but also in the intestine.

Regulating those raging (plant) hormones  -  21 Aug 2007
Dartmouth News,The team focused on the ethylene receptor ETR2, one of a family of proteins that bind to that hormone. The group found that once ETR2 had bound to an

Dwindling estrogen in menopause could make women fat: study  -  21 Aug 2007
CBC.ca,..."We put the adenovirus directly into the brains of female rats to silence the estrogen receptor in a critical brain region," Deborah Clegg,

Daiichi Sankyo and Forest Laboratories Sign Letter of Intent for ...  -  21 Aug 2007
PR Newswire (press release),...(3) AZOR(TM) is a fixed-dose combination of two antihypertensives, the calcium channel blocker amlodipine besylate and the angiotensin receptor blocker

Samaritan Licenses Tumor Inhibiting Cancer Drugs That Also ...  -  21 Aug 2007
FDA news (subscription),...for a patent covering the Peripheral Benzodiazepine Receptor (PBR) which has led to cancer drug candidates with the ability to inhibit cancerous tumors;

Daiichi Sankyo and Forest Laboratories Sign Letter of Intent for ...  -  21 Aug 2007
CNNMoney.com...(3) AZOR(TM) is a fixed-dose combination of two antihypertensives, the calcium channel blocker amlodipine besylate and the angiotensin receptor blocker

"Roadmap" Aids Malaria Vaccine Efforts  -  21 Aug 2007
Journal of American Medical Association (subscription),In addition to demonstrating that a transgenic parasite in a transgenic rodent can be used to assess antibody-mediated and antibody receptor–mediated

YM BIOSCIENCES', EUROPEAN PARTNER, ONCOSCIENCE AG, ANNOUNCES ...  -  21 Aug 2007
CNNMoney.comNimotuzumab is a humanized monoclonal antibody that targets the epidermal growth factor receptor (EGFR). To date nimotuzumab has been administered to

Ancient Protein Tells a Story of Changing Functions  -  Aug 20, 2007
New York Times,When a hormone fits into a receptor, the receptor sends a signal to another part of the cell. In work published last year, Dr. Thornton reported how his

Mechanisms that silence the estrogen receptor gene alpha in ...  -  Aug 19, 2007
eMaxHealth.com,The mechanisms that silence the estrogen receptor gene alpha (ER-α) in certain breast cancer cell lines may be closer to being unlocked, according to a

Mechanism that silences estrogen receptor gene alpha during breast ...  -  Aug 18, 2007
NewKerala.com,Washington, Aug 18 : Temple University's researchers might have discovered the mechanism that silences the estrogen receptor gene alpha (ER-a) in certain

Study Examines the Mechanisms That Silence the Estrogen Receptor ...  -  Aug 17, 2007
Newswise (press release)Newswise — The mechanisms that silences the estrogen receptor gene alpha (ER-α) in certain breast cancer cell lines may be closer to being unlocked,

Scientists Find Ancient Protein that Gives a New View of Evolution  -  Aug 20, 2007
Associated Content,They focused in particular on the glucocorticoid receptor (GR), a protein that is in humans as well as other vertebrates. This is the element that allows

UConn finds odd molecule may curb eyesight  -  Aug 20, 2007
Checkbiotech.org (press release),..."If you don't have the receptor, you don't get abnormal vessel growth in the retina," Hla said. The mice without S1P grew normal vessels when they were

Neurotrophin Receptor Plays a Key Role in Glioma Invasion  -  Aug 17, 2007
MedIndia,They identified the neurotrophin receptor p75NTR, which normally functions during development to induce neurite outgrowth and promote neuronal cell death,

Metabasis Therapeutics Reveals Preclinical Results Demonstrating ...  -  Aug 20, 2007
RTT News,The company noted that MB07811 is the first of a novel class of thyroid hormone receptor agonists that are designed to safely lower serum cholesterol and

Nicotinic receptor may make some people biologically susceptible ...  -  Aug 16, 2007
NewKerala.com,Researchers at the University of Chicago has discovered that rats most likely to self-administer addictive drugs had a particular receptor in the brain that

Kosan's Motilin Receptor Agonist, Licensed to Pfizer, Enters Phase ...  -  Aug 6, 2007
CNNMoney.com6 /PRNewswire-FirstCall/ -- Kosan Biosciences Incorporated today announced that Pfizer Inc. has initiated a Phase 1 clinical trial of motilin receptor

Nicotinic receptors may be important targets for treatment of ...  -  Aug 19, 2007
News-Medical.net,They discovered that rats most likely to self-administer addictive drugs had a particular receptor in the brain that is more responsive than the same

Athersys Reports Second Quarter 2007 Financial Results  -  Aug 17, 2007
CNNMoney.comWe recently announced the initiation of our Phase I clinical trial for ATHX-105, the company's oral, selective 5HT2c receptor agonist for treating obesity

Structure of 450 million year old protein reveals evolution's steps  -  Aug 18, 2007
Biology News Net (press release),...“We were able to see exactly how mutations in the ancient structure led to the modern receptor,�? said lead author Eric Ortlund, who carried out the research

Clinical setbacks for toll-like receptor 9 agonists in cancer  -  Aug 2, 2007
Nature.com (subscription),Cancer failures are not deterring interest in toll-like receptor agonists for other high profile indications. In June, Pfizer dropped a clinical program in

Tips from the Journals of the American Society for Microbiology  -  Aug 20, 2007
EurekAlert (press release),In the study mice carrying the human poliovirus receptor gene and lacking the interferon receptor gene (IFNAR) were sensitive to an oral challenge of the

Antibody induced modulation of thyrotropin receptor post ...  -  Aug 13, 2007
Journal of EndocrinologyThe post-translational processing of the thyrotropin receptor (TSHR) includes intra- molecular cleavage with the loss of a 50 amino-acid ectodomain region

New Receptor Gene May Illuminate MRI On Fetal Development  -  Jul 26, 2007
Science Daily (press release)Science Daily — A new receptor gene has been discovered that could help scientists learn more about events taking place in situations that are usually

Idera Pharmaceuticals Announces Publication of Preclinical Data on ...  -  Aug 14, 2007
Business Wire (press release),CAMBRIDGE, Mass.--(BUSINESS WIRE)--Idera Pharmaceuticals, Inc. (AMEX: IDP) today announced the publication of preclinical data on its stabilized immune

Scientists retrace the origins of stress  -  Aug 16, 2007
New Zealand Herald,The molecule is the "receptor protein" which binds to the stress hormone cortisol like a key fits into a lock. The scientists found that it evolved from a

Cannabinoid receptor inhibitors may prevent doxorubicin toxicity  -  Aug 10, 2007
Curetoday.com (press release),Dr. Partha Mukhopadhyay of the National Institutes of Health in Bethesda, Maryland, and colleagues analyzed the effects of CB-1 receptor inhibition in

Activation Of Liver X Receptor-Beta Lowers Cholesterol And ...  -  Jul 27, 2007
Science Daily (press release)Science Daily — In animals and humans, the proteins known as liver X receptors (LXRs) sense cholesterol levels. Upon sensing increases in cholesterol,

Specific antagonism lowers blood pressure  -  Aug 19, 2007
News-Medical.net,The authors therefore suggest that targeting the PGE2 receptor EP1 might be a viable approach to treating hypertension.

Study Unlocks Clues To Breast Cancer Cells  -  Aug 18, 2007
Post Chronicle...by Staff US researchers say they may have found a way to unlock the mechanism that silences the estrogen receptor gene alpha in certain breast cancer cell

Your Gut Has Taste Receptors  -  Aug 20, 2007
Science Daily (press release)The taste receptor T1R3 and the taste G protein gustducin are critical to sweet taste in the tongue. Research now shows these two sweet-sensing proteins are

Study unlocks clues to breast cancer cells  -  Aug 18, 2007
Kazinform,US researchers say they may have found a way to unlock the mechanism that silences the estrogen receptor gene alpha in certain breast cancer cell lines.

Variant Of Dopamine Receptor Gene Linked To ADHD  -  Aug 10, 2007
Medical News Today,Scientists believe that a variant of the dopamine receptor gene may be linked to ADHD (attention-deficit/hyperactivity disorder) and with other thinner

Researchers reveal structure of 450 million year old protein to ...  -  Aug 17, 2007
DailyIndia.com,The nanoscale image revealed the receptor's structure, down to the placement of every atom. Until now, scientists trying to unravel the evolution of the

Study unlocks clues to breast cancer cells  -  Aug 18, 2007
ImediNews,18 (UPI) — US researchers say they may have found a way to unlock the mechanism that silences the estrogen receptor gene alpha in certain breast cancer cell

Kosan's Motilin Receptor Agonist, Licensed to Pfizer, Enters Phase ...  -  Aug 6, 2007
PR Newswire (press release),..."Consistent with Kosan's focus on oncology, we successfully out-licensed KOS-2187 and our motilin receptor agonist program to Pfizer, a company with a

Study unlocks clues to breast cancer cells  -  Aug 17, 2007
The Money Times,The researchers said the study will help scientists understand how the complex pattern of estrogen receptor gene alpha methylation and transcriptional

Study unlocks clues to breast cancer cells  -  Aug 17, 2007
Earthtimes.org18 US researchers say they may have found a way to unlock the mechanism that silences the estrogen receptor gene alpha in certain breast cancer cell lines.

Study unlocks clues to breast cancer cells  -  Aug 17, 2007
United Press International18 (UPI) -- US researchers say they may have found a way to unlock the mechanism that silences the estrogen receptor gene alpha in certain breast cancer

Variant of the dopamine receptor gene may be associated with ADHD  -  Aug 7, 2007
News-Medical.net,One of the most frequently cited is a polymorphism or different type of the dopamine D4 receptor gene (DRD4) known as the 7-repeat form.

Molecular Evidence for a Link between the N363S Glucocorticoid ...  -  Aug 6, 2007
Journal of Clinical Endocrinology and Metabolism,Context: A single-nucleotide polymorphism (SNP) in the human glucocorticoid receptor (hGR) N363S (rs6195) has been the focus of several clinical studies,

Kosan’s Motilin Receptor Agonist Enters Phase I Clinical Trial  -  Aug 6, 2007
FDA news (subscription),Kosan Biosciences announced that Pfizer has initiated a Phase I clinical trial of motilin receptor agonist PF-04548043, formerly KOS-2187, for the treatment

Monogram Biosciences Launches Trofile Co-receptor Tropism Assay ...  -  Aug 6, 2007
Trading Markets,...the Trofile co-receptor tropism assay. Trofile was the pivotal test used for patient selection for Selzentry's clinical development program.

A new mechanism for respiratory syncytial virus-induced 2 ...  -  Jul 31, 2007
AJP-Lung Physiology (subscription)The 2 -AR is a member of the very large 7-transmembrane receptor superfamily of G protein-coupled receptors. 2 -AR exist in an equilibrium between at least

Polymorphisms of the Dopamine D 4 Receptor, Clinical Outcome, and ...  -  Aug 6, 2007
Archives of General PsychiatryWe drew comparisons with a single nucleotide polymorphism in the dopamine D 1 receptor (DRD1) gene, which was associated with ADHD within our cohort,

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