A Place Out of Time: Tropical Rainforests - Their Wonders and the Perils They Face. Information on rainforests, biodiversity, and environmental concerns.

Tropical Freshwater Fish: Information on tropical freshwater fish including species descriptions, tips on aquarium care, and more.

Madagascar: Information on a country rich with culture and biodiversity.

Travel Pictures: Pictures of wildlife and landscapes from around the world.

nucleoside

This page contains news and, when available, background information, onnucleoside. Links on this site lead to other sites on the web. If your site is linked from the page and you would like me to remove the link, please contact me.

nucleoside - A base (purine or pyrimidine) that is covalently linked to a 5-carbon (pentose) sugar. When the sugar is ribose, the nucleoside is a ribonucleoside; when it is 2-deoxyribose, the nucleoside is a deoxyribonucleoside. [FAO]

News archive for nucleoside.

Frequency and seriousness of lactic acidosis mean that d4T should ...  -  Aug 17, 2007
Aidsmap,Lactic acidosis is a serious side-effect of anti-HIV drugs in the nucleoside reverse transcriptase inhibitor (NRTI) class, particularly ddI and d4T,

Genelabs Technologies, Inc. Reports Financial Results for the ...  -  Aug 14, 2007
PharmaLive.com (press release),..."During the second quarter of 2007 we continued to make progress in both of our partnered HCV drug discovery programs, which include the nucleoside

Idenix Pharmaceuticals Reports Second Quarter and Six Month ...  -  Aug 2, 2007
CNNMoney.comIn addition to our HIV non-nucleoside reverse transcriptase inhibitor, which entered the clinic this year, we have a comprehensive HCV discovery engine that

HIV/HBV coinfected patients should not take entecavir unless on ...  -  Aug 17, 2007
Aidsmap,...therapy could lead lead to the development of stains of HIV with resistance to drugs from the nucleoside reverse transcriptase inhibitor (NRTI) class.

Revised Labeling for Baraclude  -  Aug 17, 2007
Facts and Comparisons,Changes to the Boxed Warnings, Microbiology, Warnings, and Precautions sections describe potential development of HIV resistance to nucleoside reverse

FDA Announces Baraclude (entecavir) is Not Recommended for HIV/HBV ...  -  Aug 16, 2007
PharmaLive.com (press release),..."Limited clinical experience suggests there is a potential for the development of resistance to HIV (human immunodeficiency virus) nucleoside reverse

IAS: Darunavir Noninferior to Lopinavir in TITAN trial  -  Jul 27, 2007
MedPage Today,In addition to the protease inhibitors, all patients received an optimized background regimen of at least two antiretrovirals from the nucleoside reverse

Anadys Pharmaceuticals Announces Strategic Restructuring and ...  -  Aug 1, 2007
CNNMoney.comANA598 is a small-molecule, non-nucleoside inhibitor of the NS5b polymerase. Anadys plans to file an IND for ANA598 in the first half of 2008.

Cyclacel Pharmaceuticals Reports Second Quarter 2007 Financial ...  -  Aug 9, 2007
Genetic Engineering News (press release),In April Cyclacel initiated a multicenter randomized Phase II clinical trial of sapacitabine (CYC682), an orally available nucleoside analog,

Patients with renal impairment often receive wrong NRTI dose ...  -  Aug 16, 2007
Aidsmap,Nearly a third of HIV-positive patients with kidney impairment received incorrect prescriptions for nucleoside reverse transcript inhibitors (NRTIs) at a

Ubisol-Aqua(TM): Coenzyme Q10 May Prevent Toxicity of HIV Drug Therapy  -  Jul 26, 2007
CNW Telbec (Communiqués de presse),...(see Zymes.com) Nucleoside reverse transcriptase inhibitors (NRTIs) inhibit replication of HIV and are central to effective HIV therapy.

144-Week Data from Gilead's Study 934 Comparing Truvada to ...  -  Jul 23, 2007
PharmaLive.com (press release),Truvada is currently the most commonly prescribed nucleoside backbone for combination HIV therapy in the United States. Truvada and Sustiva are also

Daily Digest  -  Jul 23, 2007
San Diego Daily Transcript (subscription),...spectrum antiviral drug candidate, ANX-201, when combined with approved nucleoside and nucleotide reverse transcriptase inhibitors in preclinical tests.

Pharmasset Completes Enrollment of Phase 1 Study of R7128 for HCV  -  Aug 2, 2007
CNNMoney.comR7128, a nucleoside polymerase inhibitor of HCV, is currently being evaluated in a Phase 1 clinical trial as part of Pharmasset's collaboration with Roche.

Selection of Development Candidate Triggers $0.5 Million Milestone ...  -  Aug 16, 2007
CNNMoney.comThese compounds include RDEA806 and lead compounds from our 900 series, which are non-nucleoside reverse transcriptase inhibitors (NNRTIs) for the treatment

ANX-201 Combination Therapy Demonstrates Synergistic Inhibition of ...  -  Jul 23, 2007
CNNMoney.comThe poster entitled "Synergistic Antiretroviral Activity of Pyrophosphate Analogue ANX-201 Paired with Nucleoside Reverse Transcriptase Inhibitors In Vitro"

Biota Delivers Profit After Tax of $20.2m  -  Aug 9, 2007
PharmaLive.com (press release),A research collaboration and licensing agreement with Boehringer Ingelheim was signed in November 2006 to develop and commercialise Biota’s novel nucleoside

Inhibitex Reports Second Quarter 2007 Financial Results  -  Aug 9, 2007
Business Wire (press release),Progress with FermaVir Pipeline - FermaVir’s development-stage pipeline includes FV-100, a highly potent, orally bioavailable bicyclic nucleoside analogue

Entacavir (Baraclude) Gets Boxed Warning About HIV Resistance  -  Aug 17, 2007
MedPage Today,...with the M184V mutation, which confers resistance to the nucleoside reverse transcriptase inhibitors lamivudine (3TC) and emtricitabine (Emtriva).

Bioenvision provides Evoltra (clofarabine  -  Aug 17, 2007
Checkbiotech.org (press release),Evoltra(R) (clofarabine) is a next generation purine nucleoside analog. Bioenvision holds an exclusive worldwide license (excluding US and Canada) for the

HIV Drug Startup Raises $31 Million  -  Aug 2, 2007
Private Equity Hub,This mechanism of action is different from those currently used for treatment of HIV infection such as nucleoside reverse transcriptase inhibitors and

Entecavir for HBV May Result in HIV Drug Resistance  -  Aug 16, 2007
Medscape (subscription)...are not already receiving highly active antiretroviral therapy (HAART) may result in resistance to nucleoside reverse transcriptase inhibitors (NRTIs),

Bioenvision Provides Evoltra® (clofarabine) Regulatory Update  -  Aug 16, 2007
Business Wire (press release),Evoltra® (clofarabine) is a next generation purine nucleoside analog. Bioenvision holds an exclusive worldwide license (excluding US and Canada) for the

First Head to Head Comparison of Tenofovir/ Emtricitabine Versus ...  -  Jul 27, 2007
DG NewsTruvada and Kivexa are fixed-dose combinations and the most commonly recommended and used nucleoside analogue backbone for initial antiretroviral therapy.

Rilpivirine Shows Improved Lipid Profile Compared With Efavirenz ...  -  Jul 26, 2007
DG NewsRilpivirine is a new drug in the non-nucleoside reverse transcriptase inhibitor class of antiretroviral agents. "TMC278 resulted in minimal changes in lipid

Genetic Test 100% Effective in Screening Patients With Abacavir ...  -  Jul 26, 2007
DG NewsThe test for the HLA-B*5701 allele successfully identifies patients with HIV who should not receive abacavir -- a nucleoside reverse transcriptase inhibitor

Label changes for Baraclude (entecavir) Tablets and Oral Solution  -  Jul 26, 2007
PharmaLive.com (press release),Limited clinical experience suggests there is a potential for the development to resistance HIV nucleoside reverse transcriptase inhibitors if BARCLUDE is

Progenics Presents Additional Positive Clinical Results for HIV ...  -  Jul 26, 2007
PipelineReview.com (press release),...nucleoside analog reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors, and the fusion inhibitor enfuvirtide.

IAS: Genetic Test Pinpoints Patients Who'll React to Abacavir  -  Jul 25, 2007
MedPage Today,Half were assigned to a group that received standard care - that is, no screening - and were placed on an HIV regimen containing abacavir, a nucleoside

Data Presented at International AIDS Society (IAS) Conference ...  -  Jul 24, 2007
news aktuell (Pressemitteilung),VIRAMUNE was the first member of the non-nucleoside reverse transcriptase inhibitor (NNRTI) class of anti-HIV drugs. VIRAMUNE is indicated for use in

Analysis: AIDS pipeline bursting  -  Jul 24, 2007
United Press InternationalNucleoside reverse transcriptase inhibitors and non-nucleoside reverse transcriptase inhibitors and nucleotide reverse transcriptase inhibitors all

IAS: Investigative Drugs Zero in on HIV Vulnerabilities  -  Jul 24, 2007
MedPage Today,Nucleoside reverse transcriptase inhibitors and non-nucleoside reverse transcriptase inhibitors and nucleotide reverse transcriptase inhibitors all attack

New weapons in AIDS war  -  Jul 23, 2007
Health24.com,There are four classes of ARVs currently available: Nucleoside Reverse Transcriptase Inhibitors (NRTIs). They interfere with the protein Reverse

Fighting Drug Resistance In Hepatitis C Virus  -  Jul 22, 2007
eMaxHealth.com,Understanding how some nucleoside analogues counteract excision may enhance their function as drugs. Since hepatitis C infection is a major cause of severe

Watch These Four Drug Developers  -  Aug 1, 2007
Motley Fool...and partner Wyeth have quietly been working on bringing their hepatitis C non-nucleoside polymerase inhibitor through the clinical trial process.

Ardea Biosciences, Inc. Reports Second Quarter 2007 Financial Results  -  Aug 13, 2007
Earthtimes.orgThese include RDEA806, the Company's lead non-nucleoside reverse transcriptase inhibitor (NNRTI) for the treatment of HIV, currently in Phase 1 clinical

IAS: Boosted atazanavir shows edge over unboosted in treatment ...  -  Aug 13, 2007
Aidsmap,...towards a higher rate of viral suppression after 96 weeks, fewer virological rebounds and less protease inhibitor or nucleoside analogue resistance.

Analysis: Genetic test guides AIDS therapy  -  Jul 26, 2007
Science Daily (press release)...not receive abacavir -- a nucleoside reverse transcriptase inhibitor that is one of the top two choices as the backbone for treatment combinations.

In Brief  -  Aug 2, 2007
Nature.com (subscription),...control of revenue from Bioenvision's clofarabine, a purine nucleoside analog approved in the US and Europe for pediatric acute lymphoblastic leukemia.

VicroPharma Slipping In Pre-Market Trading  -  Aug 10, 2007
Trading Markets,...can be developed independent of other HCV agents; potential delay in starting Phase 3 and increasing visibility of competing non-nucleoside products.

Tentative Approval: Lamuvidine and Zidovidine Tablets  -  Aug 9, 2007
PharmaLive.com (press release),Lamuvidine and zidovidine are both Nucleoside Reverse Transcriptase Inhibitors (NRTI) indicated for used in combination with other antiretroviral agents in

FermaVir Announces Positive Data from Recent Preclinical Studies ...  -  Aug 8, 2007
Genetic Engineering News (press release),...studies evaluating FV-100, a highly potent, orally bioavailable bicyclic nucleoside analogue for the treatment of herpes zoster infection (shingles).

DNA chips detect disease  -  Aug 6, 2007
Chemistry World,...complementary to those in the DNA strand containing the SNP of interest, except that one base is replaced by a vinyl-containing nucleoside known as cvP.

Aptivus (tipranavir) Demonstrates Potent And Durable Treatment ...  -  Aug 6, 2007
Medical News Today (press release),Viramune was the first member of the non-nucleoside reverse transcriptase inhibitor (NNRTI) class of anti-HIV drugs on the market.

Bristol-Myers Squibb Company Reports Financial Results for the ...  -  Jul 26, 2007
CNNMoney.comSales of the SUSTIVA(R) Franchise, a non-nucleoside reverse transcriptase inhibitor for the treatment of HIV, increased 21%, including a 3% favorable

Pharmasset Completes Enrollment of Phase I Study of R7128  -  Aug 3, 2007
FDA news (subscription),According to Pharmasset, R7128, a nucleoside polymerase inhibitor of HCV, is currently being evaluated in a Phase I clinical trial as part of Pharmasset’s

Cyclacel Pharmaceuticals to Announce Second Quarter 2007 Financial ...  -  Aug 3, 2007
dBusinessNews Newark (press release),Two Cyclacel drugs are in Phase II trials: sapacitabine (CYC682), an orally-available, cell cycle modulating nucleoside analog, for the treatment of

Biota Raises Relenza Claim to A$564 - A$704 Million (US$485 - US ...  -  Jul 31, 2007
Earthtimes.org...licensed to MedImmune Inc. and novel nucleoside analogues designed to treat hepatitis C virus (HCV) infections, licensed to Boehringer Ingelheim.

Several New HIV Treatment Options to Be Available Over Next 12 Months  -  Jul 30, 2007
FDA news (subscription),Johnson & Johnson submitted a new drug application (NDA) for its investigational non-nucleoside reverse transcriptase inhibitor (NNRTI) etravirine,

Tibotec submits marketing authorisation application for ...  -  Jul 29, 2007
SpiritIndia,TMC125 is an investigational next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI), being studied for use with other antiretroviral agents

archives | news | XML / RSS feed | featured

XML / RSS / Syndication options

mongabay.com features more than 350 RSS feeds to meet your specific area of interest