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micronucleus

This page contains news and, when available, background information, onmicronucleus. Links on this site lead to other sites on the web. If your site is linked from the page and you would like me to remove the link, please contact me.


micronucleus - A nucleus, distinct from and smaller than the main nucleus, but lying within the same cell. They usually arise following abnormal meiotic or mitotic telophases, where individual chromosomes or chromosome fragments do not reach the pole. [FAO]

News archive for micronucleus.

Taking the labour out of genotoxicity screening  -  Jul 25, 2007
US-PharmaTechnologist.com,By Dr Matt Wilkinson 7/25/2007 - Litron Laboratories is close to releasing an animal-free micronucleus assay that promises to allow genotoxic drug

Second Approvable Letter Issued for Trexima  -  Aug 6, 2007
Facts and Comparisons,None of the other 3 standard genotoxicity studies (Ames test, mouse lymphoma TK assay, in vivo mouse micronucleus assay) demonstrated any genotoxicity for

Players Still Trying To Widen Market For Migraine Therapy  -  Aug 17, 2007
BioWorld Online,The mouse lymphoma test, though, came up with no genotoxicity, nor did previous Ames tests and in vivo mouse micronucleus assays. Still, the FDA wants a new

FDA Issues Second Approvable Letter for Trexima  -  Aug 2, 2007
FDA news (subscription),None of the other three standard genotoxicity studies — Ames test, mouse lymphoma TK assay and in vivo mouse micronucleus assay — demonstrated any




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