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allele

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allele - A variant form of a gene. In a diploid cell there are two alleles of every gene (one inherited from each parent, although they could be identical). Within a population there may be many alleles of a gene. Alleles are symbolized with a capital letter to denote dominance, and lower case for recessive. In heterozygotes with co-dominant alleles, both are expressed. [FAO]

News archive for allele.

AnaSpec Introduces CEF Control Peptide Pool  -  21 Aug 2007
PharmaLive.com (press release),Certificate of Analysis includes data from mass spectrometry, HPLC and amino acid analysis.HLA Allele Virus Peptence Solubility.

Why Small Babies Face Heart Trouble Later  -  21 Aug 2007
PakTribune.com,Since it is transmitted less frequently to small babies, and given that small babies are more prone to cardiovascular disease, the e2 allele could be the

FDA Alters Warfarin Label to Reflect Gene Tests for Bleeding Risks  -  Aug 16, 2007
MedPage Today,At the same time, said the officials, certain single nucleotide polymorphisms in the VKORC1 gene (especially the -1639G>A allele) have been associated with

The Catechol-O-Methyltransferase Met 158 Low-Activity Allele and ...  -  Aug 6, 2007
Journal of Clinical Endocrinology and Metabolism,Results: Male carriers of the Met 158 allele had an increased risk for osteoporotic fractures (hazard ratio = 1.6; 95% confidence interval, 1.0–2.4) and for

Vascular endothelial growth factor gene polymorphisms in thyroid ...  -  Aug 17, 2007
Journal of EndocrinologyThere was a tendency of increasing the frequency of the risk allele from controls, patients without lymph node metastasis to patients with lymph node

Full Text  -  Aug 16, 2007
Science Magazine (subscription)However, analysis of the derived allele frequency spectrum shows that these regions are in fact under negative selection that is much stronger than that in

ADHD-Linked Gene Variant Associated with Good Outcomes  -  Aug 7, 2007
MedPage Today,In previous studies, the investigators found that the allele was present in 23% of 169 children with ADHD, but in only 17% of 265 healthy controls,

Variant Of Dopamine Receptor Gene Linked To ADHD  -  Aug 10, 2007
Medical News Today,The authors write "Previous studies have suggested that carriers of the risk allele [alternate form of a gene] may also have a unique neuropsychological,

Variant of the dopamine receptor gene may be associated with ADHD  -  Aug 7, 2007
News-Medical.net,..."Previous studies have suggested that carriers of the risk allele [alternate form of a gene] may also have a unique neuropsychological, clinical and

Association of Prostaglandin E Synthase 2 (PTGES2) Arg298His ...  -  Aug 6, 2007
Journal of Clinical Endocrinology and Metabolism,Carriers of the minor allele of Arg298His had a lower risk to develop the disease [odds ratio (OR) 0.63, 95% confidence interval (CI) 0.41–0.97, P = 0.04],

Association of GRIK4 With Outcome of Antidepressant Treatment in ...  -  Aug 1, 2007
Am J Psychiatry (subscription)Each gene was covered with all available markers from the HapMap Phase I (7), with a minor allele frequency of 7.5% or greater.

Cause of major subtype of glaucoma discovered  -  Aug 9, 2007
HULIQ,Analysis of additional SNPs in public databases and which were not included on the chip led to the identification of the two risk variants – allele G of

IAS: Genetic Test Pinpoints Patients Who'll React to Abacavir  -  Jul 25, 2007
MedPage Today,The other half underwent genetic screening for the HLA-B*5701 allele. Those who were found to be positive for the allele were eliminated from the study;

Cytotoxic T-Lymphocyte Associated Antigen 4 Gene Polymorphisms and ...  -  Aug 6, 2007
Journal of Clinical Endocrinology and Metabolism,Data were consistent with a dose-response effect for the G allele of CT60. Conclusion: The CT60 polymorphism of CTLA-4 maps an important genetic determinant

Genetics: Pace of change  -  Aug 15, 2007
Nature.com (subscription),...suffering effects including low blood sugar and increased insulin sensitivity, showed reduced symptoms if one allele of the osteocalcin gene was deleted

It's not just genes that sets us apart  -  Aug 13, 2007
Science Daily (press release)...full article Sex linkage -- Sex linkage is the phenotypic expression of an allele that is dependent on the gender of the individual and is directly tied to

New warfarin labeling reminds physicians about genetic tests to ...  -  Aug 17, 2007
TheHeart.Org,If a patient has the allele genotype with these gene variations, then it behooves, it's logical, the physician to use the lower initial dose.

Gene Variant Predicts Treatment Success in Depression  -  Aug 1, 2007
MedPage Today,Patients carrying two copies of the protective allele have the risk of non-response to citalopram reduced by only 11%, the researchers said,

Epilepsy Diagnosis and Management  -  Aug 16, 2007
Medscape (subscription)...[4] Of the 4 cytochrome 3A5 genotypes probed (CYP3A5*2, CYP3A5*3, CYP3A5*6, and CYP3A5*7), those with CYP3A5*3 and at least 1 variant allele (wt/*3 or

Informed consent: genetic risk and genetic counsel  -  Aug 15, 2007
Australian Life Scientist,..."If you've inherited a mutant allele from a parent, your children may be affected. It's not just mutated genes - all genes are owned collectively.

Network Medicine — From Obesity to the "Diseasome"  -  Jul 25, 2007
New England Journal of Medicine (subscription),A recent study reported that among people who carried a single copy of the high-risk allele for the FTO gene, which is associated with fat mass and obesity,

Tailor-made Antidepressants?  -  Aug 7, 2007
Science Daily (press release)...confirming the relation between allele s in the serotonin transporter gene and exposure to threatening life events in the onset of depression.

A Genetic Risk Factor for Periodic Limb Movements in Sleep  -  Aug 15, 2007
New England Journal of Medicine (subscription),Serum ferritin levels were decreased by 13% per allele of the at-risk variant (95% confidence interval, 5 to 20; P=0.002). Conclusions We have discovered a

ACPFG gets set to deliver  -  Aug 14, 2007
Australian Life Scientist,...tolerant and sensitive responses to abiotic stresses, cloning of stress tolerance genes, allele discovery and high-throughput functional gene analysis.

Analysis: Genetic test guides AIDS therapy  -  Jul 26, 2007
Science Daily (press release)Researchers said that the test for the genetic marker known as the HLA-B*5701 allele successfully identifies patients with HIV who should not receive

Advances in Neuromuscular Disease  -  Aug 15, 2007
Medscape (subscription)The risk allele identified in the present study in PON1, although different from that of the Polish study, [12] is also associated with an amino acid

Book Review: Talking Hands - What Sign Language Reveals About the ...  -  Aug 11, 2007
Blogcritics.org,In Al Sayyid, Israel, the inhabiting tribe has a notable deaf population because the recessive allele of deafness is a little less recessive there.

Full Text  -  Aug 9, 2007
Science Magazine (subscription)...occurring in the bacterial genome, can be identified by following the rapid increase in the frequency of the linked microsatellite allele (4).

Full Text  -  Aug 9, 2007
Science Magazine (subscription)Individuals inheriting a risk allele within the promoter of the serotonin transporter gene have reduced volume of area 25 and reduced functional coupling of

Obesity and Type 2 Diabetes May Be Bred in the Bone  -  Aug 9, 2007
MedPage Today,The authors affirmed the metabolic importance of the protein by observing that deleting one allele of the gene encoding for osteocalcin reversed the

The Nightmare Never Ends  -  Aug 7, 2007
Cleveland Free Times,...expanding on the first real tour it did last fall, 11 dates in the Midwest and Southwest with fellow Corporate Punishment act Allele.

Adiponectin SNP276 is associated with obesity, the metabolic ...  -  Aug 7, 2007
Am J Clin Nutr (subscription),Results: The G allele of SNP276 in intron 2 was associated with a reduced risk of obesity, MetS, and diabetes mellitus. The GT genotype relative to the GG

This Month in Archives of General Psychiatry  -  Aug 6, 2007
Archives of General PsychiatryCarriers of the risk allele also had a thinner cortex in regions important in attentional control, particularly in childhood. Volkow et al (SEE ARTICLE)

Genomic Polymorphism at the Interferon-Induced Helicase (IFIH1 ...  -  Aug 6, 2007
Journal of Clinical Endocrinology and Metabolism,Results: The alanine-carrying allele at the IFIH1 codon 946 polymorphism was present in 796 of 1204 (66%) Graves’ disease patient alleles compared with 508

Full Text  -  Aug 2, 2007
Science Magazine (subscription)The additional peaks (arrows) in the elution profiles from fer/FER plants reflect the sequence difference due to a 4-bp insertion in the fer allele.

HIV therapy leads way in personalised medicine  -  Aug 2, 2007
LabTechnologist.com,The regulator-approved, double-blinded study used to validate the effect of the HLA-B* 5701 allele on Ziagen may now enable others to conduct their own

Department of Epidemiology, Mailman School of Public Health ...  -  Aug 1, 2007
British Journal of Psychiatry (subscription),To the extent that rare alleles are important to schizophrenia, study designs based on a naive ‘common disease–common allele’ model will yield variable and

High-Dose Irinotecan More Likely to Spark Hematological Toxicity  -  Jul 31, 2007
Medscape (subscription)..."Notably, a total of 34 patients in the 4 studies were homozygous for the UGT1A1*28 allele," Dr. Hoskins presented. "Subsequent studies on larger patient

Presence of lipoprotein lipase S447X stop codon affects the ...  -  Jul 30, 2007
The Journal of Thoracic and Cardiovascular SurgeryResults: The allele frequency of lipoprotein lipase S447X stop codon was 17.5%. S447X carriers revealed significantly lower interleukin 8 levels at the

Gene Variant Discoveries On The Rise  -  Jul 30, 2007
U.S. Medicine,..."So 10 million places in this about 3 billion base pair genome, where there are common variations where the less common spelling, the less common allele is

Genetic Test 100% Effective in Screening Patients With Abacavir ...  -  Jul 26, 2007
DG NewsThe test for the HLA-B*5701 allele successfully identifies patients with HIV who should not receive abacavir -- a nucleoside reverse transcriptase inhibitor

Full Text  -  Aug 2, 2007
Science Magazine (subscription)Furthermore, a more complex inheritance pattern may also be involved in infectious diseases, as shown by the HbS allele conferring protection against severe

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