A new mechanism for respiratory syncytial virus-induced 2 ... - Jul 31, 2007 AJP-Lung Physiology (subscription)...is related to 2 -AR desensitization as a consequence of G protein-coupled receptor kinase (GRK) 2-mediated uncoupling of 2 -AR from adenylyl cyclase.
Neuropeptide S: A novel modulator of stress and arousal - Aug 13, 2007 ProHealth's ImmuneSupport.com,NPS activates its cognate G protein-coupled receptor at low nanomolar agonist concentrations and induces elevation of intracellular Ca(2+) and cAMP,
Pfizer's GORD therapy enters the clinic - Aug 6, 2007 DrugResearcher.com,Erythromycin is a motilin G-protein coupled receptor agonist that mediates the hormone motilin, which is secreted by the small intestine and stimulates GI
PerkinElmer Launches New Assay Development Service For Advanced - Aug 8, 2007 BioResearch Online (press release),The new service offers comprehensive assay solutions for high-value g-protein coupled receptor (GPCR) and kinase cell-based screening including highly
EPIX Pharmaceuticals Announces Positive Results from Phase 2a ... - Aug 7, 2007 PharmaLive.com (press release),Discovered and designed using EPIX's proprietary G-protein coupled receptor (GPCR) modeling and optimization technology, EPIX is developing PRX-08066 to
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