sumatriptan succinate

This page contains recent news articles, when available, and an overview of sumatriptan succinate but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

sumatriptan succinate (when available)

Pharmacology and use:
Sumatriptan, an antimigraine drug, is structurally similar to serotonin. It is thought that the cerebral blood vessel constriction induced by activation of 5-HT1 receptors on those vessels may contribute to the antimigrainous effect of sumatriptan in humans. For the treatment of migraine attacks with or without aura in adults

Mechanism Of Action:
Sumatriptan stimulates 5-HT receptors of the 1D subtype, most likely presynaptic receptors, resulting in selective vasoconstriction of inflamed and dilated cranial blood vessels in the carotid circulation. Sumatriptan also blocks the release of vasoactive neuropeptides from perivascular trigeminal axons in the dura mater during migraine and may inhibit the release of inflammatory mediators from the trigeminal nerve.

News Articles on Sumatriptan

Drug firms may exceed growth targets  -  ‎Apr 19, 2009‎
...with about 20 per cent growth, thanks to good revenues from sumatriptan succinate, an authorised generic version of GlaxoSmithKline (GSK)'s Imitrex. Business Standard

Bedford Laboratories(TM) to Begin Shipping Sumatriptan Succinate ...  -  ‎Feb 25, 2009‎
Sumatriptan Succinate Injection is not for use in the management of hemiplegic or basilar migraine. Bedford Laboratories will supply Sumatriptan Succinate PR Newswire (press release)

Par Pharmaceutical Reports Fourth Quarter and Full Year 2008 Results  -  ‎Mar 2, 2009‎
Revenues for the fourth quarter 2008 increased 4.0% compared with the same period in 2007 due primarily to the launch of sumatriptan succinate injection, PR Newswire (press release)

Wockhardt gets USFDA nod for Ranitidine syrup  -  ‎Feb 23, 2009‎
Recently, the company had received final approval from the US Food and Drug Administration (USFDA) to market Sumatriptan Succinate injectable/ injection, Myiris.com

Only 6 drug majors post better results  -  04 Feb 2009
This was mainly due to exclusive gains from the launch of an authorised generic version of GlaxoSmithKline's Imitrex (Sumatriptan Succinate) in the US since Business Standard,

Dr. Reddy's Labs Turns To profit in Q3 - Update  -  Jan 20, 2009
The company said the growth was driven by the successful launch of the authorized generic version of GlaxoSmithKline's Imitrex, or sumatriptan succinate in RTT News,

Dr. Reddy’s Q3 FY09 Revenue at Rs. 18401 million, EBITDA at Rs ...  -  Jan 20, 2009
...the successful launch of the authorized generic version of GlaxoSmithKline’s Imitrex® (generic version: sumatriptan succinate), in late November 2008. WELT ONLINE,

Dr. Reddy’s Laboratories back in black  -  Jan 20, 2009
Sumatriptan is an authorised generic version of GlaxoSmithKline’s Imitrex (generic version: sumatriptan succinate). Imitrex is prescribed for the treatment Hindu,

Ranbaxy Lab swings to loss for FY 08  -  Jan 22, 2009
The company settled all matters relating to possible patent litigation with GlaxoSmithKline (GSK) relating to Sumatriptan Succinate Tablets, Myiris.com,

Dr. Reddy’s Launches Authorized Generic Version of Imitrex Tablets  -  Dec 1, 2008
In October 2006, the Company announced that it had settled patent litigation with GlaxoSmithKline relating to sumatriptan succinate tablets, Pharmaceutical Processing,

Par Pharmaceutical Companies Inc to ship Sumatriptan Succinate ...  -  Nov 7, 2008
A Sumatriptan Succinate Injection is indicated for the acute treatment of migraine attacks with or without aura and the acute treatment of cluster headache Trading Markets (press release),

Par Pharmaceutical Begins Shipment of Sumatriptan Injection  -  Nov 6, 2008
Sumatriptan Succinate Injection is indicated for 1) the acute treatment of migraine attacks with or without aura and 2) the acute treatment of cluster Earthtimes (press release),

الـ LSD... أنقذني من الصداع العنقودي!  -  Nov 19, 2008
علاوة على ذلك، أظهرت البيانات الصحية التي قدمتها خدمات إدارة المعلومات أن المبيعات السنوية من دواء Sumatriptan Succinate �?ي الولايات المتحدة خلال العامين الجريدة,

Ranbaxy-GSK submits IND application for respiratory inflammation ...  -  Oct 13, 2008
The terms of the settlement, allowed Ranbaxy to distribute a generic version of Sumatriptan Succinate tablets in the 25mg, 50mg and 100mg strengths in the domain-B,

Wockhardt gets nod for Promethazine hydrochloride injection  -  Sep 26, 2008
Recently, the company received tentative approval from USFDA to make and sell Sumatriptan Succinate injection, in the strength of 6 mg/0.5 ml. Myiris.com,

Wockhardt gets USFDA nod for Promethazine hydrochloride injection  -  Sep 28, 2008
Recently, the company has received tentative approval from USFDA to produce and market Sumatriptan Succinate injection, in the strength of 6 mg/0.5 ml. Stock Watch,

LSD cured my headache  -  Oct 6, 2008
Besides, according to IMS Health data, annual sales of sumatriptan succinate tablets in the US over 2006/07 were $950m. Why spend millions developing a Independent,

Wockhardt gets tentative approval for Sumatriptan Succinate  -  Aug 25, 2008
Sumatriptan Succinate is the generic version of GlaxoSmithKline (GSK) Imitrex injection. The drug is prescribed for the treatment of a migraine attack with TopNews,

Wockhardt Gets Tentative US FDA OK For Sumatriptan Succinate  -  Aug 24, 2008
BY) has received tentative approval from the US Food and Drug Administration to make and sell Sumatriptan Succinate, the generic version of GlaxoSmithKline Smartmoney.com

Dr Reddy`s may miss sales forecast, say analysts  -  Jul 5, 2008
Dr Reddy's has forecasted a 25 per cent sales growth in the financial year 2009 mainly due to the demand for the generic version of sumatriptan succinate. Business Standard,

Indian generic companies may tread Ranbaxy path  -  Jun 18, 2008
Ranbaxy had said “all matters relating to possible patent litigation�? with GSK on the latter’s Imitrex (sumatriptan succinate) have been settled. Economic Times,

Meet Malav, the charismatic CEO of Ranbaxy  -  Jun 11, 2008
...and settled with GSK over Sumatriptan Succinate, the generic version of GSK's Imitrex; Ranbaxy would launch the generic drug in the US in December 2008. Rediff,

Par Increases Its Migraine Drug-Profit Share  -  May 7, 2008
Under the revised deal, Par's profit share from sales of sumatriptan succinate injection, a generic version of GlaxoSmithKline's Imitrex Injection that NJBIZ,

Dr Reddy’s signs off a forgettable year  -  May 21, 2008
...blockbuster anti-migrane drug, Imitrex, generically known as Sumatriptan Succinate which is worth around $1 billion in sales per year. Sify,

Malav at work  -  May 5, 2008
...and settled with GSK over Sumatriptan Succinate, the generic version of GSK's Imitrex; Ranbaxy would launch the generic drug in the US in December 2008. Business Standard,

Ranbaxy's net profit at USD 39mn (Rs 1530 mn), + 19%  -  Apr 22, 2008
Ø The Company settled all matters relating to possible patent litigation with GlaxoSmithKline relating to Sumatriptan Succinate Tablets, the generic version Moneycontrol.com (press release),

BeaconEquity.com - POZEN Inc. (POZN) Receives FDA Approval for ...  -  Apr 21, 2008
Treximet is GSK’s proposed brand name for a proprietary single tablet containing sumatriptan succinate, a 5-HT 1B/1D agonist formulated with GSK’s RT Emailwire

Stocks on the Move - PTSC, POZN, GSK, VNGM  -  Apr 16, 2008
Trexima is a proprietary single tablet containing sumatriptan succinate and naproxen sodium. How They Trade: POZN has a 52 week high of $19.75 and a 52 week TransWorldNews (press release),

BUYINS.NET: FTWR, ICXT, POZN, ACTC, EDNE, LNVGY Have Also Been On ...  -  Apr 14, 2008
Trexima is a proprietary single tablet containing sumatriptan succinate and naproxen sodium. The company entered into a collaboration and license agreement Trading Markets (press release),

Generic Ultram  -  Feb 29, 2008
Do not reaction hives difficulty breathing sumatriptan succinate. Ultram is one, of credit cards. Make sure that are related; to an unborn baby. Fatman Games

Aurobindo gets provisionary approval to produce Sumatriptan ...  -  Feb 1, 2008
Aurobindo Pharma Ltd has got provisionary approval to develop and market the Sumatriptan Succinate Tablets in dosage of 25mg, 50mg and 100mg. Stock Watch,

Aurobindo gets approval for Sumatriptan Succinate tabs  -  Feb 1, 2008
Sumatriptan Succinate Tablets are the generic equivalent of GlaxoSmithKline's Imitrex® Tablets, which are indicated for the treatment of acute migraine Moneycontrol.com (press release),

Aurobindo gets US FDA nod for Sumatriptan tablets  -  Jan 31, 2008
The annual sales of the Sumatriptan succinate tablets in the US were around 950 million dollars last year, according to data from international consulting Hindu,

Aurobindo Pharma gets USFDA nod for Sumatriptan  -  Jan 31, 2008
MUMBAI: Aurobindo Pharma has received tentative approval from the US Food and Drug Administration to manufacture and market Sumatriptan Succinate tablets Economic Times,

Aurobindo Pharma gets FDA tentative nod for generic version of GSK ...  -  Jan 31, 2008
Annual sales of Sumatriptan Succinate Tablets in the US to end-March 2007, were 950 mln usd, according to IMS Health (nyse: RX - news - people ) data. Forbes,

Aurobindo Pharma gets US nod for sumatriptan tablets  -  Feb 1, 2008
...on Friday it received tentative approval from the US Food and Drug Administration for its sumatriptan succinate tablets, used to treat acute migraine. Therapeutics Daily (subscription) (press release),

Ranbaxy, GSK settle Imitrex patent issue  -  Jan 21, 2008
NEW DELHI: Ranbaxy announced that it has settled all matters relating to possible patent litigation with GlaxoSmithKline regarding Sumatriptan Succinate Times of India,

Ranbaxy, GlaxoSmithKline reach settlement  -  Jan 21, 2008
Sumatriptan Succinate tablets are the generic version of GlaxoSmithKline’s Imitrex Tablets. The terms of the settlement provide that Ranbaxy may distribute Hindu,

Aurobindo gets USFDA nod for generic Imitrex  -  Jan 31, 2008
Aurobindo Pharma has received the US Food & Drug Administration (FDA) nod to market sumatriptan succinate in the United States. Business Standard,

Indian Companies Settle Drug Suit  -  Jan 21, 2008
Ranbaxy, India's largest pharmaceutical company by sales, said the settlement over sumatriptan succinate, the generic version of GlaxoSmithKline's Imitrex, Wall Street Journal

Ranbaxy settles generic sale dispute with GSK  -  Jan 21, 2008
The Gurgaon-based company said it has settled all matters relating to possible patent litigation with GSK regarding Sumatriptan Succinate tablets, Economic Times,

India's Ranbaxy says settles issues with GSK over generic Imitrex ...  -  Jan 20, 2008
...settled all matters with GlaxoSmithKline (NYSE:GSK) (GSK) related to its Sumatriptan Succinate tablets, the generic version of GSK's Imitrex tablets. CNNMoney.com

Ranbaxy, GSK settle Imitrex patent dispute  -  Jan 20, 2008
Ranbaxy Laboratories has settled a patent litigation in the US with drug major GlaxoSmithKline (GSK) relating to Imitrex (sumatriptan succinate tablets), Business Standard,

India Ranbaxy settles with GlaxoSmithKline on Imitrex  -  Jan 20, 2008
Under the terms of the settlement, Ranbaxy may sell a generic version, sumatriptan succinate tablets, in multiple strengths in the United States from Reuters

Ranbaxy Announces Settlement of Possible Imitrex(R) Litigation ...  -  Jan 21, 2008
The terms of the settlement provide that Ranbaxy may distribute a generic version of Sumatriptan Succinate Tablets (in the 25 mg, 50 mg and 100 mg SunHerald.com,

Ranbaxy settles patent litigation with GlaxoSmithKline  -  Jan 21, 2008
The terms of the settlement provide that Ranbaxy may distribute a generic version of sumatriptan succinate tablets (in the 25mg, 50mg and 100mg strengths) Trading Markets (press release),

Ranbaxy Settles Imitrex Dispute with GlaxosmithKline  -  Jan 21, 2008
The settlement allows Ranbaxy to distribute the generic version of the drug, Sumatriptan Succinate Tablets in the United States starting at the expected International Business Times,

Ranbaxy settles patent dispute with GSK  -  Jan 21, 2008
Dr Reddy’s, which has an agreement with GSK to sell “authorised generic�? version of the drug will also be selling sumatriptan succinate tablets, Hindu Business Line,

• Ranbaxy to Sell Copycat Migraine Med  -  Jan 21, 2008
The settlement provides that India-based Ranbaxy, which has its US headquarters in Princeton, may distribute sumatriptan succinate tablets, NJBIZ,

Ranbaxy Labs Settles With GlaxoSmithKline On Imitrex - Quick Facts ...  -  Jan 21, 2008
As per the settlement, Ranbaxy might sell a generic version, sumatriptan succinate tablets, in multiple strengths in the United States from December 2008. RTT News,

Ranbaxy, GSK Settles ‘Imitrex’ Patent Dispute  -  Jan 23, 2008
Dr. Reddy, which has an agreement with GSK to sell authorised generic drug version will also be selling sumatriptan succinate tablets, or generic Imitrex Stock Watch,

Dr. Reddy's, Ranbaxy Announce Settlements  -  Jan 28, 2008
...announced it had settled matters relating to possible patent litigation with GlaxoSmithKline (GSK) over Imitrex (sumatriptan succinate) tablets. FDA news (subscription),

GSK deal to net Ranbaxy $90 mn in ’09  -  Jan 21, 2008
A Ranbaxy spokesperson insisted the firm would enjoy a full exclusivity period for sumatriptan succinate (the chemical name of Imitrex) for 25mg, Livemint,

Nonsurgical Treatment for Hallux Abducto Valgus with Botulinum Toxin A  -  Jan 17, 2008
The patient took sumatriptan succinate as needed for migraines and denied allergies. Her family history was significant for cardiovascular disease and high Journal of the American Podiatric Medical Association (subscription)

Pozen Announces Trexima(TM) (Sumatriptan Succinate and Naproxen ...  -  Nov 1, 2007
POZEN Inc. (NASDAQ:POZN) announced today that its amended response to the FDA approvable letter for Trexima received on August 1, 2007 has been accepted for WELT ONLINE,

Is Your Headache a Migraine？  -  Oct 29, 2007
...(sumatriptan succinate) Tablets. Now I have a migraine-specific medicine that works for me. My advice to people who regularly get bad headaches is to learn 金�?界,

BUYINS.NET: SNP, CTEL, NINE, OFIX, POZN, ADVR Have Been Added To ...  -  Oct 23, 2007
Trexima is a proprietary single tablet containing sumatriptan succinate and naproxen sodium. The company entered into a collaboration and license agreement Trading Markets (press release),

POZN: Sees Gains on Friday from FDA Update of Trexima(TM)  -  Oct 5, 2007
Trexima is a proprietary single tablet containing sumatriptan succinate, a 5-HT 1B/1D agonist formulated with GSK's RT Technology(TM), and naproxen sodium, Trading Markets (press release),

[an error occurred while processing this directive] [an error occurred while processing this directive] [an error occurred while processing this directive] Brand Names/Synonyms:
sumatriptan succinate is also known by the following brand names and/or synonymsCHEMBANK1724; Imigran; Imitrex; Sumatran; Sumatriptan; Sumatriptan Succinate; Sumatriptanum [Inn-Latin]; Sumax

Drug Category:
sumatriptan succinate is categorized under the following by the FDA: Vasoconstrictor Agents; Selective Serotonin Agonists; ATC:N02CC01

Dosage Forms:
Tablets; Injection; Nasal spray

Absorption:
~15%

Interactions:
Interactions for Sumatriptan:

Ergot-containing drugs have been reported to cause prolonged vasospastic reactions. Because there is a theoretical basis that these effects may be additive, use of ergotamine-containing or ergot-type medications (like dihydroergotamine or methysergide) and sumatriptan within 24 hours of each other should be avoided.

MAO-A inhibitors reduce sumatriptan clearance, significantly increasing systemic exposure. Therefore, the use of sumatriptan succinate tablets in patients receiving MAO-A inhibitors is contraindicated .

Selective serotonin reuptake inhibitors (SSRIs) (e.g., fluoxetine, fluvoxamine, paroxetine, sertraline) have been reported, rarely, to cause weakness, hyperreflexia, and incoordination when coadministered with sumatriptan. If concomitant treatment with sumatriptan and an SSRI is clinically warranted, appropriate observation of the patient is advised.

Chemical IUPAC Name:
1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide

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