ranitidine hydrochloride

This page contains recent news articles, when available, and an overview of ranitidine hydrochloride but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

ranitidine hydrochloride
(when available)

Pharmacology and use:
Ranitidine, a histamine H2-receptor antagonist similar to cimetidine and famotidine, is used to treat gastrointestinal disorders such as Helicobacter pylori-related peptic ulcer disease. For the treatment of peptic or duodenal ulcers

Mechanism Of Action:
Ranitidine competes with histamine for binding at H2 receptors on gastric parietal cells. Competitive inhibition results in reduced basal and nocturnal gastric acid secretion. Ranitidine also decreases the amount of gastric acid released in response to stimuli such as food, caffeine, insulin, betazole, or pentagastrin. Other actions of ranitidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

News Articles on Ranitidine

Wockhardt gets US nod for anti-ulcer syrup  -  ‎Feb 26, 2009‎
Profile, Research) said on Thursday it has secured US Food and Drug Administration approval to sell an alcohol-free syrup of ranitidine hydrochloride, Reuters India

Wockhardt to launch generic version of ulcer drug Ranitidine syrup ...  -  ‎Mar 1, 2009‎
Administration (US FDA) for marketing the alcohol-free syrup containing 15mg/ml Ranitidine hydrochloride, which is used for ulcers and hyperacidity. Prdomain Business Register (press release)

Stocks to watch: Satyam, DLF, TCS, Infosys, Wockhardt, GAIL  -  ‎Feb 26, 2009‎
Wockhardt has received US Food and Drug Administration approval to sell an alcohol-free syrup of ranitidine hydrochloride, used to treat ulcers and Economic Times

Glenmark Pharma`s US arm gets USFDA nod for Ranitidine Hydrochloride  -  Nov 19, 2008
Generics its US arm had received a final approval from US Food and Drug Administration (USFDA) to market Ranitidine Hydrochloride on prescription basis. Myiris.com,

Marksans Pharma gets certificate of suitability by EDQM  -  Nov 2, 2008
..."With the grant of the certificate of suitability for Ranitidine Hydrochloride drug substance by EDQM, the European markets have opened for access for the Business Standard,

Market Live  -  Nov 2, 2008
11:50 am: Marksans Pharma Ltd has received certificate of suitability for Ranitidine Hydrochloride drug substance from the European Directorate for the Economic Times,

Brookstone Pharmaceuticals Launches Generic to Zantac Syrup  -  Jul 17, 2008
Brookstone Pharmaceuticals, LLC today announced the introduction of Ranitidine Syrup, a generic equivalent to Zantac® Syrup (ranitidine hydrochloride). PharmiWeb.com (press release),

Terahertz radiation sheds light on pharmaceutical analysis  -  Mar 25, 2008
Terahertz spectral features of the drug ranitidine hydrochloride, polymorphic forms I and II. Signature peaks for each form can be identified easily using SPIE Newsroom,

[an error occurred while processing this directive] [an error occurred while processing this directive] [an error occurred while processing this directive] Brand Names/Synonyms:
ranitidine hydrochloride is also known by the following brand names and/or synonymsAchedos; Acidex; Atural; Axoban; Coralen; Curan; Duractin; Ezopta; Gastrial; Gastrosedol; HSDB 3925; Istomar; Logast; Mauran; Melfax; Microtid; Noctone; Ptinolin; Quantor; Quicran; RND; Radinat; Randin; Raniben; Ranidine; Ranin; Raniogas; Raniplex; Ranisen; Raniter; Ranitidina [Inn-Spanish]; Ranitidine; Ranitidine Base; Ranitidine Hcl; Ranitidine Hydrochloride; Ranitidine [Usan:Ban:Inn]; Ranitidinum [Inn-Latin]; Ranitiget; Rantacid; Rantidine; Rantidine Hcl; Ratic; Raticina; Sampep; Sostril; Taural; Terposen; Trigger; Tritec; Ul-Pep; Ulceranin; Ulcex; Ultidine; Urantac; Verlost; Vesyca; Vizerul; Weichilin; Weidos; Xanidine; ZANTAC; Zantab; Zantac; Zantac 150; Zantac 75; Zantac in Plastic Container; Zantadin; Zantic; [Inn-Latin]

Drug Category:
ranitidine hydrochloride is categorized under the following by the FDA: Anti-ulcer Agents; Histamine Antagonists; ATC:A02BA02; ATC:A02BA07

Dosage Forms:
CAPSULE; LIQUID; SOLUTION; TABLET

Absorption:
50% absorbed after oral administration

Interactions:
Interactions for Ranitidine:

Coadministration of TRITEC with clarithromycin resulted in increased plasma ranitidine concentrations (57%), increased plasma bismuth trough concentrations (48%), and increased 14- hydroxy- clarithromycin plasma concentrations (31%). Coadministration with aspirin results in a slight decrease in the rate of salicylate absorption that is clinically unimportant. Coadministration with a high dose of antacid (170 mEq) results in a 28% decrease in plasma concentrations of ranitidine and may decrease plasma concentrations of bismuth from TRITEC. These effects are clinically insignificant.

For information on drug interactions associated with ranitidine, refer to the ZANTAC ® package insert.





Chemical IUPAC Name:
N'-[2-[[5-(dimethylaminomethyl)-2-furyl]methylsulfanyl]ethyl]-N-methyl-2-nitro-ethene-1,1-diamine

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