cefuroxime axetil

This page contains recent news articles, when available, and an overview of cefuroxime axetil but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

cefuroxime axetil (when available)

Pharmacology and use:
Cefuroxime, a second-generation cephalosporin, is used to treat severe upper and lower respiratory tract infections, skin infections, otitis media, and surgical prophylaxis. For the treatment of the following infections (respiratory, skin, soft tissue, urinary tract infections, ear, nose, throat infectsion) caused by; S. pneumoniae, H. influenzae, staphylococci, S. pyogenes (group A ß-hemolytic streptococci), E. coli, P. mirabilis, Klebsiella sp, coagulase-negative staph. Also used to treat acute bacterial bronchitis in patients with COPD

Mechanism Of Action:
Cefuroxime, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that cefuroxime interferes with an autolysin inhibitor.

News Articles on Cefuroxime

Effectiveness and Safety of Short-Course Vs Long-Course Antibiotic ...  -  Aug 5, 2008
Short course therapy with cefuroxime axetil for group A streptococcal tonsillopharyngitis in children. Pediatr Infect Dis J. 1998;17(6):452-457. 25. RedOrbit,

Personal Health A Threat in a Grassy Stroll: Lyme Disease  -  Jul 15, 2008
Other options include cefuroxime axetil (Ceftin) and erythromycin. But these guidelines are controversial. They have been challenged by a nonprofit medical New York Times,

Q&A: DISEASE'S CAUSE, CURES  -  03 Jul 2008
Most people can be cured with a few weeks of oral antibiotics such as doxycycline, amoxicillin, or cefuroxime axetil. Those diagnosed with later stages of Newsday,

Rosiglitazone may Slow Progression of Diabetic Retinopathy  -  Jun 26, 2008
Some of their products include Albenza (albendazole), Ceftin (cefuroxime axetil), Flonase (fluticasone proprionate), and Paxil (paroxetine hydrochloride). Medi News Direct,

Beware of Bug Bites and Stings  -  Jun 19, 2008
Antibiotics commonly used for oral treatment include doxycycline, amoxicillin, or cefuroxime axetil (Ceftin). People with certain illnesses related to the Food Consumer,

Orchid Chemicals gains on strong FY 2008 numbers  -  May 29, 2008
...received approval from the US Food & Drug Administration (US FDA) for its abbreviated new drug application for cefuroxime axetil tablets. NDTV.com,

Sheriff ramps up prescription drug battle  -  May 31, 2008
Cefuroxime axetil is an antibiotic. Pravastatin is a cholesterol medication. Diclofenac sodium is an anti-inflammatory drug. Cymbalta treats depression. Princeton Times Leader,

Aurobindo Pharma receives nine product approval from MCC - South ...  -  May 12, 2008
Product Name : Zinoxime Active ingredient : Cefuroxime Axetil Dosage Form : Tablet Strength: 125mg, 250mg,500mg Category : Anti-infective 5. Equity Bulls,

Ranbaxy's net profit at USD 39mn (Rs 1530 mn), + 19%  -  Apr 22, 2008
During the quarter, Ranbaxy received approval from the US FDA to manufacture and market Cefuroxime Axetil Oral Suspension USP, 125 mg/5mL and 250 mg/5mL. Moneycontrol.com (press release),

Information about Lyme Disease Treatment  -  Mar 27, 2008
Oral antibiotics — usually doxycycline for adults and children older than 8, or amoxicillin or cefuroxime axetil for adults, younger children and pregnant Los Angeles Chronicle,

Injectable Antibiotic Protects Against Lyme Disease in Mice  -  Apr 4, 2008
As for treatment, the CDC suggests that two to four weeks of repeated oral antibiotics -- such as doxycyline, amoxicillin, and cefuroxime axetil -- can U.S. News & World Report,

Emerging Antimicrobial Resistance in Neisseria gonorrhoeae: Urgent ...  -  Apr 14, 2008
Cefuroxime axetil, 1 g, also meets the less stringent efficacy criteria, but it has poor pharmacodynamic characteristics that may select for stepwise Annals of Internal Medicine

Orchid receives US FDA approval for Cefuroxime Axetil ANDA  -  Feb 20, 2008
2008 has announced that it has received approval from the US FDA for its ANDA (Abbreviated New Drug Application) for Cefuroxime Axetil Tablets. Equity Bulls,

Orchid gets US FDA approval for Cefuroxime Axetil ANDA  -  Feb 19, 2008
Orchid Chemicals & Pharmaceuticals has got US FDA approval for its ANDA (Abbreviated New Drug Application) for cefuroxime axetil tablets. Myiris.com,

Orchid receives two US FDA approvals  -  Mar 9, 2008
Apart from granisetron hydrochloride tablets, Orchid also got approval for its Abbreviated New Drug Application (ANDA) cefuroxime axetil tablets. Express Pharma,

Orchid Chemicals cleared by FDA to make, market generic version of ...  -  Feb 19, 2008
Cefuroxime Axetil is an orally administered antibiotic used to treat mild-to-moderate infections. The current market size of the tablets is around 40 mln Euro2day,

Glaxo's fatal jab  -  Feb 22, 2008
Ceftazidime which is used for the most serious infections, and Cefuroxime Axetil which is an ear, nose and throat infection tablet or syrup. NW Evening Mail,

Orchid gets US FDA approval for its drug  -  Feb 20, 2008
...and Pharmaceuticals Ltd Wednesday said it has received an approval from US Food and Drug Administration (US FDA) for its Cefuroxime Axetil tablets. Thaindian.com,

FDA Approves Ranbaxy’s Generic Ceftin  -  Feb 13, 2008
The FDA’s Office of Generic Drugs has approved Indian drugmaker Ranbaxy Laboratories’ generic pediatric formulation of the antibiotic cefuroxime axetil, FDA news (subscription),

Ranbaxy Labs receives USFDA for Cefuroxime Axetil  -  06 Feb 2008
MUMBAI: Ranbaxy Laboratories has received approval from the US Food and Drug Administration to manufacture and market Cefuroxime Axetil for Oral Suspension Economic Times,

Symptoms by treatment, Part 1  -  Sep 18, 2007
Antibiotics, such as cephalexin, clarithromycin, cefuroxime axetil, cefixime and a host of other generic names, may cause inflammation of the intestinal Sun.Star,

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cefuroxime axetil is also known by the following brand names and/or synonymsAncef; Biofuroksym; Ceclor; Ceclor Cd; Cedax; Cefditoren; Cefizox; Cefotan; Ceftin; Ceftizoxime Sodium; Cefurax; Cefuril; Cefuroxim; Cefuroxime; Cefuroxime Axetil; Cefuroxime Free Acid; Cefuroxime Sodium; Cefuroxime Sodium Salt; Cefuroxime [Usan:Ban:Inn]; Cefuroxime and Dextrose in Duplex Container; Cefuroximo [Inn-Spanish]; Cefuroximum [Inn-Latin]; Cefzil; Cephuroxime; Ceptaz; Duricef; Elobact; Fortaz; Keflex; Keftab; Kefurox; Kefurox in Plastic Container; Kerurox; Mandol; Maxipime; Mefoxin; Monocid; Omnicef; Oraxim; Rocephin; Sharox; Tazicef; Vantin; Velosef; Zinacef; Zinacef Danmark; Zinacef in Plastic Container; Zinat; Zinnat

Drug Category:
cefuroxime axetil is categorized under the following by the FDA: Anti-bacterial Agents; Cephalosporins; ATC:J01DC02

Dosage Forms:
POWDER; POWDER FOR SOLUTION; TABLET

Absorption:
Well absorbed from the GI tract (bioavailability is 37-52%)

Interactions:
-->Interactions for Cefuroxime:

Drug/Laboratory Test Interactions: A false-positive reaction for glucose in the urine may occur with copper reduction tests (Benedictís or Fehlingís solution or with ClinitestÒ tablets) but not with enzyme-based tests for glycosuria. As a false-negative result may occur in the ferricyanide test, it is recommended that either the glucose oxidase or hexokinase method be used to determine blood plasma glucose levels in patients receiving cefuroxime.

Cefuroxime does not interfere with the assay of serum and urine creatinine by the alkaline picrate method.

Chemical IUPAC Name:
4-(carbamoyloxymethyl)-8-[2-(2-furyl)-2-methoxyimino-acetyl]amino-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylic acid

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