Zyrtec

This page contains recent news articles, when available, and an overview of Zyrtec but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Zyrtec
(when available)

Pharmacology and use:
Cetirizine, the active metabolite of the piperazine H1-receptor antagonist hydroxyzine, is used to treat chronic idiopathic urticaria, perennial allergic rhinitis, seasonal allergic rhinitis, allergic asthma, physical urticaria, and atopic dermatitis. For the relief of symptoms associated with seasonal allergic rhinitis, perennial allergic rhinitis and the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria

Mechanism Of Action:
Cetirizine competes with histamine for binding at H1-receptor sites on the effector cell surface, resulting in suppression of histaminic edema, flare, and pruritus. The low incidence of sedation can be attributed to reduced penetration of cetirizine into the CNS as a result of the less lipophilic carboxyl group on the ethylamine side chain.CetirizineZyrtec.txt" -->Brand Names/Synonyms:
Zyrtec is also known by the following brand names and/or synonymsAlerlisin; CHEMBANK1856; Cetirizina [Spanish]; Cetirizine; Cetirizinum [Latin]; Cetrizine Hcl; Cetryn; Formistin; Hitrizin Film Tablet; Reactine; Setir; Virlix; Ziptek; Zirtek; Zyrlex; Zyrtec

Drug Category:
Zyrtec is categorized under the following by the FDA: Anti-allergic Agents; Antihistamines; ATC:R06AE07; ATC:R06AE09

Dosage Forms:
tablets

Absorption:
mean peak plasma concentration (Cmax) of 114 ng/mL at a time (Tmax) of 2.2 hours postdose was observed for cetirizine

Interactions:
Interactions for Cetirizine:

Pharmacokinetic interaction studies with cetirizine in adults were conducted with pseudoephedrine, antipyrine, ketoconazole, erythromycin and azithromycin. No interactions were observed. In a multiple dose study of theophylline (400 mg once daily for 3 days) and cetirizine (20 mg once daily for 3 days), a 16% decrease in the clearance of cetirizine was observed. The disposition of theophylline was not altered by concomitant cetirizine administration.

Drug-Drug Interactions: No clinically significant drug interactions have been found with theophylline at a low dose, azithromycin, pseudoephedrine, ketoconazole, or erythromycin. There was a small decrease in the clearance of cetirizine caused by a 400-mg dose of theophylline; it is possible that larger theophylline doses could have a greater effect.





Chemical IUPAC Name:
2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]aceticacid

Huckaby tied to January missing girl report  -  21 Apr 2009
...mom had consumed alcohol and had some kind of pills - I doubt they were benzos, else she WOULD have gotten popped (maybe Zyrtec "drugs"- Keystone cops. Tracy Press

(Pennsylvania) Torture. Waterboarding. Disgusting.  -  21 Apr 2009
...[color=white]Zyrtec vs allegra Can you take albuterol with allegra When symptoms develop, they may be confused with those of flu may accompany these Politicker

Johnson & Johnson 1Q Net Drops 2.5% On Falling Sales  -  ‎Apr 14, 2009‎
...slipped 2.5% as a stronger dollar ate into foreign sales and prior-year revenue was boosted by the over-the-counter debut of the allergy drug Zyrtec. Wall Street Journal

Seasonal allergies increase in spring  -  ‎Apr 14, 2009‎
Falkenberry said he takes Zyrtec and it is just as effective. Martin said he uses non-drowsy antihistamines to stop congestion, Benadryl to help him sleep Daily O'Collegian

Itchy eyes? Watery nose? Blame the trees  -  ‎Apr 2, 2009‎
...“There are many newer medications in the last 20 years that are now available over the counter — Zyrtec, Claritin and generic forms. Auburn Journal

Allergy Alert!  -  ‎Apr 16, 2009‎
A stop at Safeway for Claritin, Zyrtec or Allegra can also provide fast relief. “If it's enough to want to do something about it then Claritin or the other Whitman Pioneer

Private-label OTC Drugs Post Solid Gains in 2008, According to Kline  -  ‎Apr 8, 2009‎
...asthma, and sinus medications were up 17.3% as a result of strong sales from Johnson & Johnson's Zyrtec brand, as well as its equivalent private-label PR Newswire (press release)

10 questions for Dr. Kenneth Backman  -  ‎Apr 12, 2009‎
The newer ones, like Claritin and Zyrtec, are actually very safe. Claritin is a little less potent that Zyrtec. The older ones, like Benadryl, work OK, Connecticut Post

More variety in today's pollen count  -  ‎Apr 15, 2009‎
According to the Zyrtec allergy medication homepage www.zyrtec.com tree pollens are among the worst culprits in human allergy symptoms. Cedartown Standard

Avoidance, pills, shots can help with spring allergies  -  ‎Apr 10, 2009‎
Dunn advises allergy sufferers to try first over-the-counter allergy medicines -- like Claritin, Zyrtec or the cheaper generic brands. WRAL.com

Sneeze the day  -  ‎Apr 4, 2009‎
..."Zyrtec is a miracle drug for me for coughing and sneezing," she says. "Claritin doesn't work for me, but with Zyrtec I have absolutely no side effects. Martinsburg Journal

Cold Snap Helps Allergy Patients  -  ‎Apr 7, 2009‎
He says over the counter medicines like Claritin or Zyrtec help some people. He recommends getting tested to see what you are allergic to. WDEF News 12

The Best Medicine  -  ‎Apr 19, 2009‎
A new product focus is especially relevant as Johnson & Johnson begins shipping a new three-count convenience pack of its Zyrtec allergy medication, CSP Daily News

Risks and potential in the polypill  -  ‎Apr 1, 2009‎
In the evenings I take another niacin, generic simvastatin, a baby aspirin, and generic Zyrtec (to offset a side-effect of the morning’s heart pill). ZDNet

Johnson & Johnson's 1Q In Line  -  ‎Apr 14, 2009‎
...the prior-year period, as its over-the-counter division faced a tough prior-year comparison because of Zyrtec stocking in the first quarter of 2008. Morningstar.ca

Seasonal change spurs students' sniffles, sneezes  -  ‎Apr 8, 2009‎
Claritin and Zyrtec are good for daytime relief, and Benadryl can help at night, Matthews said. The recent thunderstorms, Matthew said, have caused new Echo Online (subscription)

Sneezy, runny? 5 tips to tame allergies  -  ‎Apr 8, 2009‎
Medications such as antihistamines (ie Benadryl, Claritin, Allegra, Zyrtec, etc.) may be prescribed and will help stop the itchy eyes and runny nose. ABC15.com (KNXV-TV)

About this author:  -  ‎Mar 31, 2009‎
Nike (NKE), J. Crew (JCG), Viva (owned by Kimberly-Clark, KMB), Tylenol and Zyrtec (owned by JNJ), Estee Lauder (EL), and All State (ALL). Seeking Alpha

Too busy to see your GP? Then ask me  -  ‎Apr 4, 2009‎
Avoid antihistimines with a sedating side-effect, such as chlorphenamine (Piriton), in favour of “non-drowsy� treatments such as cetirizine (Zyrtec). Times Online

Common drugs can help allergic rhinitis  -  ‎Mar 29, 2009‎
Second-generation anti-histamines have been developed such as Xyzal, Zyrtec, Allegra, Claritin, Clarinex, and Alavert that do not cross the Daytona Beach News-Journal

Johnson & Johnson F1Q09 (Qtr End 03/29/09) Earnings Call Transcript  -  ‎Apr 14, 2009‎
The first quarter results for 2008 included the launch of Zyrtec OTC. Excluding the impact of Zyrtec the Consumer business grew approximately 1% Seeking Alpha

Is it a cold?  -  ‎Apr 3, 2009‎
Over the counter antihistamines can be very effective and recently 2 of them that were prescription only have become available without; Zyrtec (certirizine) YourHub.com

Gear Guide to California Wildflowers  -  ‎Apr 2, 2009‎
Zyrtec Allergy Relief: Just cause you’re allergic to nature’s love dust doesn’t mean that you should be prevented from bathing in the beauty of Marin’s Tips from the T-List

Springtime wreaks havoc on allergy sufferers  -  ‎Apr 18, 2009‎
The most common over-the-counter medications used by allergy sufferers include Claritin, Zyrtec, Benadryl, Chlortrimeton, Tavist, Drixoral and Nasalcrom. Nevada Appeal

Actress and Mom Alison Sweeney Teams Up With the American ...  -  ‎Apr 2, 2009‎
..."I initially didn't realize the medicines that I've relied on, SUDAFED(R) and ZYRTEC-D(R) made by McNeil Consumer Healthcare Division of McNEIL-PPC, Inc., PR Newswire (press release)

Problematic pollen  -  ‎Apr 17, 2009‎
Claritin and Zyrtec are two OTCs recommended by Lovick, who said both are non-sedating and require a single dose each day. Children under the age of two ENC Today

Five Fabulous Finds: Kids music, burgers and CFL bulbs free!  -  ‎Apr 17, 2009‎
How about freebies like a trial pair of Acuvue Contact Lenses, Nature Made Liquid Softgels, Zyrtec or Prilosec OTC. Even get free subscriptions to Yachting, WalletPop

Allergic rhinitis: market evolution  -  ‎Apr 3, 2009‎
In the United States, loratadine (Claritin and Alavert) and cetirizine (Zyrtec) have been the major antihistamine entrants into the OTC market. Nature.com (subscription)

Consumer Packaged Goods Invited to Enter Largest Innovation Survey ...  -  ‎Apr 15, 2009‎
Unilever, Dr Pepper Snapple, Duracell, Oust, Pantene, Olay, Zyrtec, CoverGirl and other brands, by entering the 2010 Product of the Year USA awards. Business Wire (press release)

Armed against allergies  -  ‎Apr 6, 2009‎
Allergy medicines were among the most asked about by pharmacy shoppers, and the antihistamine Claritin, closely followed by Zyrtec, were among the top drugs Baltimore Sun

Spring Allergy Survival Guide: When Do You Need To See The Doctor?  -  ‎Apr 18, 2009‎
Longer-lasting alternatives are loratidine (Claritin) or cetirizine (Zyrtec), which typically don't cause drowsiness and come in once-a-day formulas. Medical News Today (press release)

Advice for the allergy  -  ‎Apr 13, 2009‎
The doctor also recommends Claritin and Zyrtec. Other stronger medications are available by prescription. "If it's driving you nuts certainly go to see your WAVY-TV

Use only as directed  -  ‎Apr 5, 2009‎
Of those 17 spots, 12 were for (in order): Zyrtec, an over-the-counter allergy medication; Citrucel Fiber Supplement With Calcium; Advil PM, a combination Boston Globe

Bless you! Is your misery index up? Must be allergies  -  ‎Apr 10, 2009‎
He suggested Zyrtec and Claritin as “pretty good to start,� and Zaditor antihistamine eye drops for itchy, red eyes and a saline rinse. Anderson Independent Mail

PBMs Are Taking New Steps to Influence Consumer Behavior, Push ...  -  ‎Apr 8, 2009‎
He points, as an example, to the brand allergy medicine Zyrtec (cetirizine), which costs $91 as a brand, $25 as an OTC brand, and $16 as the CVS generic OTC Atlantic Information Services, Inc.

Editorial: State drug price Web site cries out for improvement  -  ‎Apr 11, 2009‎
...really charging $15654 for an Rx of amoxicillin, $860603 for a 30-day supply of Ambien or $24729 for Zyrtec), but evidence of flat-out noncompliance. Schenectady Gazette

Sorting Out Allergy Treatments  -  ‎Apr 8, 2009‎
Claritin or Zyrtec The more traditional ones are Chloropheniramine (Chlor-Trimeton, Pediacare, Triaminic) or diphenhydramine (Benadryl) cause drowsiness but EmpowHer

BEFORE THE BELL: US Stk Futures Flat To Lower  -  ‎Apr 14, 2009‎
...slipped 2.5% as a stronger dollar ate into foreign sales and prior-year revenue was boosted by the over-the-counter debut of the allergy drug Zyrtec. Wall Street Journal

Tháng tư và bệnh dị ứng phấn hoa  -  ‎Apr 16, 2009‎
Thuốc chống dị ứng bao gồm có các loại thuốc kê đơn và không cần kê đơn như Benadryl, Clarinex, Zyrtec hay Allegra; các loại thuốc giảm xung huyết há»?ng như Dân Trí

الحبوب Ù?ÙŠ أصابع اليد .. التشخيص والعلاج  -  ‎Mar 30, 2009‎
...cream)ØŒ مع استخدام مضاد للحساسية مثل (zyrtec) قرص واحد يومياً، ÙˆÙ?ÙŠ حال كون الإصابة قوية ولا تستجيب للعلاج Ù?قد نحتاج إلى أخذ أقراص كورتيزون Ù„Ù?ترة محددوة. الشبكة الإسلامية

强生公布2009年第一季度业绩  -  ‎Apr 14, 2009‎
...由於与2008年推出ZYRTEC 相关的贸易首次产生存货,销售é¢?比照å?—到负é?¢å½±å“?。 强生第一季度全ç?ƒè?¯å“?销售é¢?为58亿美元,较上年å?ŒæœŸä¸‹é™?了10.1%,其中ç»?è?¥ä¸šç»©ä¸‹é™? 凤凰网

Starker US-Dollar drückt Ergebnis von Johnson & Johnson  -  ‎Apr 14, 2009‎
Im Vorjahr hatte allerdings der Start des rezeptfreien Handels mit dem Anti-Allergikum Zyrtec den Umsatz getrieben. Mit einem Ergebnis je Aktie von Frankfurter Allgemeine Zeitung

I na cestovní lékárniÄ?ce se dá uÅ¡etÅ™it  -  ‎Apr 13, 2009‎
Zyrtec, originální antihistaminikum, které je běžnÄ› dostupné ve vÅ¡ech lékárnách bez lékaÅ™ského pÅ™edpisu za cenu cca 100 KÄ?. Bolest u dÄ›tí: ŘeÅ¡ením, tn.cz

強生公佈2009年第一季度業績  -  ‎Apr 14, 2009‎
...由於與2008年推出ZYRTEC 相關的貿易首次產生存貨,銷售é¡?比照å?—到負é?¢å½±éŸ¿ã€‚ 強生第一季度全ç?ƒè—¥å“?銷售é¡?為58億美元,較上年å?ŒæœŸä¸‹é™?了10.1%,其中經營業績下é™? 財華網

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