Zyrtec

This page contains recent news articles, when available, and an overview of Zyrtec but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Zyrtec (when available)

Pharmacology and use:
Cetirizine, the active metabolite of the piperazine H₁-receptor antagonist hydroxyzine, is used to treat chronic idiopathic urticaria, perennial allergic rhinitis, seasonal allergic rhinitis, allergic asthma, physical urticaria, and atopic dermatitis. For the relief of symptoms associated with seasonal allergic rhinitis, perennial allergic rhinitis and the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria

Mechanism Of Action:
Cetirizine competes with histamine for binding at H₁-receptor sites on the effector cell surface, resulting in suppression of histaminic edema, flare, and pruritus. The low incidence of sedation can be attributed to reduced penetration of cetirizine into the CNS as a result of the less lipophilic carboxyl group on the ethylamine side chain.CetirizineZyrtec.txt" -->Brand Names/Synonyms:
Zyrtec is also known by the following brand names and/or synonymsAlerlisin; CHEMBANK1856; Cetirizina [Spanish]; Cetirizine; Cetirizinum [Latin]; Cetrizine Hcl; Cetryn; Formistin; Hitrizin Film Tablet; Reactine; Setir; Virlix; Ziptek; Zirtek; Zyrlex; Zyrtec

Drug Category:
Zyrtec is categorized under the following by the FDA: Anti-allergic Agents; Antihistamines; ATC:R06AE07; ATC:R06AE09

Dosage Forms:
tablets

Absorption:
mean peak plasma concentration (Cmax) of 114 ng/mL at a time (Tmax) of 2.2 hours postdose was observed for cetirizine

Interactions:
Interactions for Cetirizine:

Pharmacokinetic interaction studies with cetirizine in adults were conducted with pseudoephedrine, antipyrine, ketoconazole, erythromycin and azithromycin. No interactions were observed. In a multiple dose study of theophylline (400 mg once daily for 3 days) and cetirizine (20 mg once daily for 3 days), a 16% decrease in the clearance of cetirizine was observed. The disposition of theophylline was not altered by concomitant cetirizine administration.

Drug-Drug Interactions: No clinically significant drug interactions have been found with theophylline at a low dose, azithromycin, pseudoephedrine, ketoconazole, or erythromycin. There was a small decrease in the clearance of cetirizine caused by a 400-mg dose of theophylline; it is possible that larger theophylline doses could have a greater effect.

Chemical IUPAC Name:
2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]aceticacid

Commissioners approve insurance actuary study  -  16 Sep 2008
This plan also provides coverage for over-the-counter allergy medications (ie Claritin, Alavert, Zyrtec) that Health Choice does not cover. Alva Review-Courier,

Child's runnynose shows vbody's defenses  -  Sep 14, 2008
Newer second generation antihistamines like Claritin, Allegra, or Zyrtec usually have little or no sedative effect and therefore are good choices for Evansville Courier & Press,

Grab the tissues: Ragweed a troublesome, common allergen  -  Sep 12, 2008
Also effective for some untreated patients in the throes of the pollen season are Claritin and Zyrtec, once prescription allergy drugs that now are Norwich Bulletin,

Generic drugs hurt Longs Drug Stores pharmacy sales  -  Sep 4, 2008
...fell 1.4 percent overall at Longs in August. The switch of an allergy medicine, Zyrtec, from prescription to over-the-counter also cut into pharmacy sales. Bizjournals.com,

2008 Fall Allergy Capitals(TM) Reveal Most Challenging US Cities ...  -  Sep 4, 2008
..."Allergy sufferers should know what allergens trigger their symptoms and, if appropriate, manage them by taking a medication like ZYRTEC(R) that can Earthtimes (press release),

Drug Retailers May Show Weakness  -  Sep 2, 2008
Economic weakness, the transition of Zyrtec to over-the-counter, safety concerns on certain drugs, and a general lack of innovation continue to weigh on Barron's

UCB to cut 17% of work force as part of revamp  -  Aug 28, 2008
The company also said that within a year, its patents on its two biggest drugs, Zyrtec and Keppra, will expire. Zyrtec treats allergy symptoms while Keppra MarketWatch

The You Docs: Six things you must know about your medications  -  Aug 20, 2008
Many drugs sound the same -- witness Zyrtec (for allergies) and Zyprexa (schizophrenia and bipolar disorder). Their generic names (cetirizine and Seattle Post Intelligencer

Small Patients, Big Consequences in Medical Errors  -  Sep 14, 2008
Karen Rhodes was giving her 2-year-old daughter, Lanie, the prescription medication Zyrtec for allergies three times a day, as the label indicated. New York Times,

Somehow, DC Rates Relatively Well on Allergy List  -  Sep 4, 2008
Today the Asthma and Allergy Foundation of America unveiled its 2008 Fall Allergy Capitals list, which is sponsored by the makers of allergy medicine Zyrtec DCist.com,

Walgreens August Sales Increase 6.0 Percent  -  Sep 3, 2008
In addition to the calendar day shifts, August prescriptions filled were negatively impacted by 0.6 percentage points due to the switch of Zyrtec from Business Wire (press release),

No Place Is Free From Allergies In America, According To The ...  -  Aug 22, 2008
..."Allergy sufferers should know what allergens trigger their symptoms and, if appropriate, manage them by taking a medication like ZYRTEC® that can alleviate North American Press Syndicate,

New Report on Pfizer Inc.  -  Sep 2, 2008
Overview 162 Sales forecast 163 Zyvox 165 Overview 166 Sales forecast 167 Selzentry 169 Overview 170 Sales forecast 171 Respiratory 173 Zyrtec/Zyrtec D IT Business Net,

Longs Drug Stores August Same-Store Sales Down 1.4% - Update  -  Sep 4, 2008
In addition, a reduction in cold, flu, and allergy prescriptions, primarily due to the impact of the switch of the prescription allergy medicine Zyrtec to RTT News,

Benadryl Tops In Brand Buzz As Hay Fever Season Begins  -  Aug 18, 2008
Claritin was a close second with 30% having heard recently about the brand, and 25% said they had heard of Zyrtec. (Responses are from daily polling of 5000 MediaPost Publications,

UCB Pharma to Rebrand as Specialty Company  -  Sep 3, 2008
...to compensate for two blockbuster drugs going off-patent—the allergy drug Zyrtec (cetirizine) and the epilepsy treatment Keppra (levetiracetam). PharmExec.com,

More Pharma Job Losses At UCB And J&J  -  Aug 28, 2008
UCB faces eroding sales as patents expire on its two biggest meds, the Zyrtec antihistamine and Keppra treatment for epilepsy. Pharmalot,

UPDATE 2-Belgian drugmaker UCB to cut 2000 jobs worldwide  -  Aug 28, 2008
In UCB's case, this requires moving from reliance on older drugs such as hayfever medicine Zyrtec and epilepsy drug Keppra, which face patent expiry in the Reuters

UCB revamps with 2000 job cuts  -  Aug 28, 2008
The allergy drug Zyrtec also went off patent in the US at the end of 2007. "Patent expires are challenging times," said Roch Doliveux, CEO of UCB. FiercePharma,

It usually starts with a sneeze around 4 pm  -  Aug 25, 2008
I've tried Flonase, Benadryl and even Zyrtec, the last of which gave me real hope since it used to be available only by prescription. Examiner.com

Pollen levels to stay high  -  Aug 24, 2008
Over-the-counter antihistamines such as Claritin and Zyrtec also can provide relief, but Cookingham said immunotherapy may be the best bet in the long run. Port Huron Times Herald,

The You Docs tips for the week  -  Aug 23, 2008
Many drugs sound the same - witness Zyrtec (for allergies) and Zyprexa (schizophrenia and bipolar disorder). Their generic names (cetirizine and olanzapine) Telegraph-Journal,

What's Going Around  -  Aug 21, 2008
Physicians recommend trying over the counter allergy medications such as Claritin or Zyrtec. If they don’t work to control symptoms, see your doctor for KAKE,

North Queensland, September 6  -  Sep 6, 2008
Novice (332 Horses Judge S Schoo): P Comiskey, Suzie Acres, 177, D Cogill, Rivoli Romulus, 173, W Head, Emma, 170, T Paton, Fiddler, 169, K Brown, Zyrtec, Courier Mail,

No Place Safe From Allergies  -  Sep 5, 2008
...but there are also indoor triggers such as pet dander and dust mites. The report was paid for by McNEIL-PPC Inc., maker of the allergy drug Zyrtec. Washington Post,

Over-the-Counter Relief for Investors  -  Sep 5, 2008
...version of the heartburn drug Prilosec, and Cetirizine, which has the same active ingredient found in Pfizer's allergy medication, Zyrtec. Barron's

UCB plans to cut 2000 jobs as part of revamping  -  Aug 28, 2008
The company also said that within a year, its patents on its two biggest drugs, Zyrtec and Keppra, will expire. It also recently was cleared by the US to MarketWatch

Watch out for drug names that look, sound alike  -  Sep 1, 2008
Or the patient misspells or mispronounces one of his drugs, and a health worker assumes it's the schizophrenia drug Zyprexa, not the antihistamine Zyrtec. The Associated Press

Health checkup: Drug mix-ups  -  Sep 10, 2008
Some other frequently mixed-up drugs are Sarafem (to treat severe premenstrual symptoms) and Serophene (infertility); Zyprexa (antipsychotic) and Zyrtec Rochester Democrat and Chronicle,

Drugstore Rebate Report: August 2008  -  Sep 9, 2008
Specific promotions included: a back-to-school incentive from J&J's McNeil Consumer Healthcare rewarding shoppers who buy two Children's Zyrtec products In-Store Marketing Institute (Subscription),

How to treat an insect sting  -  Sep 8, 2008
Local itching and burning can be treated with any type of antihistamine, including Benadryl, Claritin and Zyrtec. Use ibuprofen or acetaminophen for pain. Southtown Star,

Longs Reports Preliminary August Retail Drug Store Sales  -  Sep 4, 2008
In addition, a reduction in cold, flu, and allergy prescriptions, primarily due to the impact of the switch of the prescription allergy medicine Zyrtec to Earthtimes (press release),

Fall allergies? Things could be a lot worse  -  Sep 3, 2008
Although rankings might mean little for the miserable allergy sufferer, doctors say over-the-counter medications such as Claritin and Zyrtec can help. Colorado Springs Gazette,

Nothing to sneeze at  -  Sep 3, 2008
By DANIELLE HATCH Cross Canadian Ragweed sounds like something you'd pick up while camping in the woods, but there's no need to reach for the Zyrtec just Peoria Journal Star,

Asthma treatments have plenty of puff  -  Sep 3, 2008
...behaviour and competition from anti-histamines such as Pfizer's (PFE) Zyrtec, now sold over-the-counter by New York-listed Johnson & Johnson (JNJ). Interactive Investor,

Growth Amid Pharma Cutbacks  -  Aug 31, 2008
...operations as it prepares for generic competition to its allergy drug Zyrtec and its epilepsy drug Keppra, which will lose patent protection next year. Chemical & Engineering News

Older People in Danger from Common Drugs  -  Aug 28, 2008
Consider cetirizine (Zyrtec), fexofenadine (Allegra) and loratadine (Claritin) as alternatives. • Doxazosin (Cardura), prazosin (Vasoflex), and Terazosin NewsMax.com,

Pfocus on Pfizer: Still an attractive pharmaceutical company  -  Aug 27, 2008
PFE drugs that recently lost patent protection (Norvasc, Zyrtec, and Camptosar) all saw sales declines of from 16%–75%. With half of US drugs coming off Stockhouse,

Drugs Manufactured By Indian Company Win Approval Even During ...  -  Aug 27, 2008
Ranbaxy is India’s largest drug maker and brought these eighteen generic drugs to the market, including Zyrtec and the cholesterol drug Pravachol. InjuryBoard.com,

Woman presents with visual disturbance in left eye  -  Aug 22, 2008
She had a rash in the past associated with penicillins and was on Zyrtec (cetirizine, Pfizer) for seasonal allergies. Social history was significant for a OSN SuperSite (subscription),

Ragweed misery: How to find relief  -  Aug 20, 2008
Visiting the corner drugstore can be helpful since many allergy medications, such as Claritin and Zyrtec, are available over the counter. Louisville Courier-Journal,

Turning the Business Over to the Staff  -  Aug 18, 2008
...“In the last year, we were responsible for Johnson & Johnson’s [product display] launch of Zyrtec,�? he says. Stores featuring displays created by NJBIZ,

Loma Linda University Medical Center Announces 'Everyday ...  -  Aug 18, 2008
Speaking of Women's Health is supported by National Sponsors Wal-Mart, Lifetime, Tylenol, Zyrtec, Kellogg's, L'Oreal Paris, Mabelline New York, Garnier, Earthtimes (press release),

Sneeze alert (AUDIO)  -  Aug 18, 2008
McAndrew had tried over-the-counter antihistamines like Claritin and Zyrtec, which work well for people with mild ragweed allergies. GoErie.com,

Perrigo Company F4Q08 (Qtr End 06/28/08) Earnings Call Transcript  -  Aug 18, 2008
Cetirizine was launched in January ahead of the launch of the national brand Zyrtec. Despite six competitive Cetirizine approvals at market formation, Seeking Alpha,

Doctor: Allergy season now reaching its peak  -  Sep 4, 2008
A whole slew of options are available, many of which are now over-the-counter drugs such as Claritin or Zyrtec. However, what works for one person may not Janesville Gazette,

UCB to slash 17% of work force  -  Aug 29, 2008
The move is also in preparation for the expiration of patents on the drugmaker's Zyrtec, an antihistamine, and Keppra, an epilepsy medicine. SmartBrief,

Johnson & Johnson's Vice Chairman Poon To Retire In March  -  Sep 12, 2008
The consumer products business benefited from the new nonprescription allergy pill -- Zyrtec, which now has 27% share of the non-prescription allergy market Trading Markets (press release),

UCB计划�?员17%  -  Aug 28, 2008
UCB还称，公�?�最�?�?两�?�?�物Zyrtec 新浪网,

Alergie dokáže potrápit i na podzim  -  Sep 2, 2008
Pokud nás ještě žádná alergie nepřekvapila, měli bychom si pro jistotu s sebou na chalupu přibalit lék první pomoci při alergické reakci – například Zyrtec. Novinky,

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