Trimethadione

This page contains recent news articles, when available, and an overview of Trimethadione but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Trimethadione (when available)

Pharmacology and use:
Paramethadione and trimethadione are anticonvulsants indicated in the control of absence (petit mal) seizures that are refractory to treatment with other medications. Dione anticonvulsants are used in the treatment of epilepsy. They act on the central nervous system (CNS) to reduce the number of seizures. Used in the control of absence (petit mal) seizures that are refractory to treatment with other medications.

Mechanism Of Action:
Dione anticonvulsants reduce T-type calcium currents in thalamic neurons, including thalamic relay neurons. This raises the threshold for repetitive activity in the thalamus, and inhibits corticothalamic transmission. Thus, the abnormal thalamocortical rhythmicity, which is thought to underlie the 3-Hz spike-and-wave discharge seen on electroencephalogram(EEG) with absence seizures, is dampened.

News Articles on Trimethadione

Brand Names/Synonyms:
Trimethadione is also known by the following brand names and/or synonymsA 2297; Absentol; Absetil; Convenixa; Convexina; Edion; Epidione; Epidone; Epixal; Etydion; Mino-Aleviatin; Minoaleuiatin; Minoaleviatin; Neo-Absentol; Petidion; Petidon; Petilep; Petimalin; Pitmal; Ptimal; Tioxanona; Tredione; Tricione; Tridilona; Tridion; Tridione; Tridone; Trilidona; Trimedal; Trimedone; Trimetadione; Trimethadion; Trimethadione; Trimethdione; Trimethin; Trimetin; Trioxanona; Triozanona; Tromedone; Troxidone

Drug Category:
Trimethadione is categorized under the following by the FDA: Anticonvulsants; ATC:N03AC02

Dosage Forms:
TABLET

Absorption:
Not Available

Interactions:
Not Available

Chemical IUPAC Name:
3,5,5-trimethyloxazolidine-2,4-dione

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