Tridihexethyl

This page contains recent news articles, when available, and an overview of Tridihexethyl but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Tridihexethyl (when available)

Pharmacology and use:
Tridihexethyl is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. Tridihexethyl is an antimuscarinic, anticholinergic drug. Used as an adjunct in the treatment of peptic ulcer disease

Mechanism Of Action:
Tridihexethyl binds the muscarinic acetylcholine receptor. It may block all three types of muscarinic receptors including M-1 receptors in the CNS and ganglia, M-2 receptors in the heart (vagus) and M-3 receptors at the parasympathetic NEJ system. The muscarinic acetylcholine receptors mediate various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Tridihexethyl inhibits vagally mediated reflexes by antagonizing the action of acetylcholine. This in turn reduces the secretion of gastric acids in the stomach.

News Articles on Tridihexethyl

Brand Names/Synonyms:
Tridihexethyl is also known by the following brand names and/or synonymsPathilon; Propethonum; Tridihexethyl; Tridihexethyl Chloride

Drug Category:
Tridihexethyl is categorized under the following by the FDA: Antispasmodics; Anticholinergic Agents; ATC:A03AB08

Dosage Forms:
TABLETS; CAPSULES

Absorption:
Not Available

Interactions:
Not Available

Chemical IUPAC Name:
(3-cyclohexyl-3-hydroxy-3-phenyl-propyl)-triethyl-ammonium

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