Toprol XL

This page contains recent news articles, when available, and an overview of Toprol XL but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

AstraZeneca's Toprol Raises Risk of Death, Stroke, Study Says  -  May 12, 2008
By Trista Kelley May 13 (Bloomberg) -- AstraZeneca Plc's Toprol XL, given before surgery to prevent heart complications, increases the danger of stroke or Bloomberg

KV Pharmaceutical gets FDA approval for generic Toprol  -  May 15, 2008
Toprol-XL in the 50 mg strength recorded total branded and generic dollar volume in 2007 of $585 million, KV said, citing IMS America. Hemscott,

POISE study questions value of perioperative beta-blockers  -  May 15, 2008
The publication of a large-scale randomised trial with extended-release metoprolol succinate (AstraZeneca’s Toprol XL) has re-ignited a debate over whether Pharma Times (subscription),

KV Pharmaceutical gets FDA approval for generic heart drug dosage  -  May 15, 2008
...its 50 mg strength of a generic version of hypertension and heart failure drug Toprol-XL, a branded product of drug maker AstraZeneca (NYSE: AZN). Bizjournals.com,

Generic Heart Drug Dosage Approved  -  May 21, 2008
This product is a generic version of AstraZeneca's Toprol-XL. Metoprolol succinate extended-release tablets are indicated for the treatment of hypertension FDA news (subscription),

FDA Lifts Warning Letter for Watson Facility, Key Approvals to Follow  -  May 16, 2008
Watson Pharmaceuticals expects to launch generic versions of Toprol-XL and Prilosec this year now that the FDA has lifted a warning letter for the firm’s FDA news (subscription),

Betting on beta blockers  -  May 13, 2008
Many others have come along since, including atenolol (Tenormin), bisoprolol (Zebeta), and metoprolol (Lopressor, Toprol XL). If you're not sure whether a Gather.com,

Boost in generic drugs means greater savings  -  May 10, 2008
...medications such as cholesterol-reducing Zocor, antihypertensive Toprol-XL and antidepressant Zoloft — more generics are available than ever before. Deseret News,

FDA Lifts Warning Letter for Watson Facility, Key Approvals to Follow  -  May 6, 2008
Watson Pharmaceuticals expects to launch generic versions of Toprol-XL and Prilosec this year now that the FDA has lifted a warning letter for the firm’s FDA news (subscription),

Why Are So Many Pills Used To Treat Heart Failure?  -  May 23, 2008
The most effective beta-blockers for heart failure are carvedilol (Coreg) and metoprolol succinate (Toprol XL). At first, patients on a beta blocker may Tampa Tribune,

Beta Blockers Linked to 800000 Deaths  -  May 18, 2008
Half were given the beta-blocker metoprolol—sold by AstraZeneca as Toprol XL—two to four hours before and 30 days following surgery. Newsinferno.com,

KV Pharmaceutical Company Announces Approval For The 50 mg  -  May 16, 2008
This product is a generic version of AstraZeneca's branded product, Toprol-XL and the 50 mg strength recorded total branded and generic dollar volume in Pharmaceutical Online (press release),

European Stock Futures Gain: SocGen, Corporate Express May Rise  -  May 12, 2008
AstraZeneca Plc may move after researchers said the drugmaker's Toprol XL, given before surgery to prevent heart complications, increases the danger of Bloomberg

Daily Briefing  -  May 14, 2008
AstraZeneca PLC's Toprol XL, given before surgery to prevent heart complications, increases the danger of stroke or death, researchers said. The News Journal,

Market Report -- In Play (KV.A)  -  May 15, 2008
KV Pharmaceutical announces approval for the 50 mg strength of generic version of Toprol-XL Co announces that it has received final approval from the US MSN Money

Banks suffer after RBS rights issue  -  23 Apr 2008
...complex" as they will be distorted by internal restructuring, the acquisition of MedImmune and the move to make generic versions of Toprol XL in the US. Telegraph.co.uk,

FDA Investigation of Generic Drug Called Inadequate by ConsumerLab ...  -  Apr 16, 2008
It reported last month that generic versions of anti-hypertensive Toprol XL do not all dissolve like the original and vary in composition. PharmaLive.com (press release),

Personal Health Hypertension: In Retreat, but Hardly Vanquished  -  Apr 22, 2008
...a combination of a diuretic and angiotensin II receptor blocker; Norvasc, a calcium channel blocker; and Toprol XL, a beta blocker. New York Times,

Effectiveness of generics called into question  -  Apr 10, 2008
In March independent testing centre ConsumerLab.com urged the FDA to review the performance of a generic equivalent to AstraZeneca's Toprol XL (metoprolol In-PharmaTechnologist.com,

Bad Timing for AstraZeneca's Good Data  -  Apr 2, 2008
But even so, AstraZeneca needed the good news it got, since generic competition against its Toprol-XL compound has eaten into its sales this year. Motley Fool

Merck sales edge up, net nearly doubles  -  Apr 22, 2008
With the payment, Merck's ownership stakes in Toprol-XL, Pulmicort, Rhinocort and Symbicort ends, according to an AstraZeneca statement. Philadelphia Inquirer,

After the switch to generics, then what?  -  Apr 7, 2008
Since 2004, Autrey, 52, had controlled his high blood pressure with Toprol XL, a brand-name medication made by AstraZeneca. So had his elderly mother, Bradenton Herald,

Generics called into question  -  Apr 4, 2008
...of a new generic for Toprol XL, a once-a-day version of a high blood pressure drug that is the fifth-most-prescribed medicine in the United States. Albany Democrat Herald,

Save Money on Prescriptions  -  Apr 8, 2008
...antihypertensive Toprol-XL and antidepressant Zoloft -- more generics are available than ever before, and chances are your medication is among them. Kiplinger.com,

Officials Question Safety Of Overseas Drug Manufacturers  -  Apr 1, 2008
...lowering Lipitor, narcotic pain reliever acetominiphin with hydrocodone, antibiotic amoxicillen and high blood pressure fighters, Toprol-XL and Norvasc. NBC 4.com,

Merck Still Cashing In On AstraZeneca Deal  -  Feb 28, 2008
In 2008, Merck had no choice but to give up the $182 million that has been coming in annually for Toprol-XL, Pulmicort, Rhinocort and Symbicort. Forbes,

2nd UPDATE: AstraZeneca: Merck To Keep Interest In Some Products  -  Feb 28, 2008
The deal, originally signed in 1982, covers the sale and distribution of several AstraZeneca's drugs, including heart drug Toprol XL, asthma treatment CNNMoney.com

AstraZeneca Provides An Update on the Status of its Arrangements ...  -  Feb 28, 2008
The products covered by the Partial Retirement include Toprol-XL™, Pulmicort™, Rhinocort™ and Symbicort™. AstraZeneca made contingent payments in respect of PharmaLive.com (press release),

FDA starts inspecting stalled Watson facility  -  Feb 18, 2008
...hyperactivity disorder, and of the antihypertensives Cardizem LA (extended-release diltiazem) and Toprol XL (extended-release metoprolol succinate). OutSourcing-Pharma.com,

KV Pharmaceutical Company (KV-A) Completes Unaudited Fiscal 2007 ...  -  Feb 18, 2008
...the subsequent approval and launch after fiscal 2007 year-end of metoprolol succinate extended release tablets (generic alternative to Toprol-XL(R), Lifescience-online,

Proper handwashing isn't a waste of time  -  Feb 6, 2008
Q: My doctor prescribed Toprol-XL several years ago, and it worked well. Last week, my pharmacist refilled my prescription with generic metoprolol succinate Daily Press,

Manhattan Research Ranks the Top Pharmaceutical Branded Websites ...  -  Feb 4, 2008
Seasonale, Seroquel, Singulair, Strattera, Tamiflu, Topamax, Toprol XL, Tricor, Valtrex, Vytorin, Yasmin, Yaz, Zocor, Zoloft, Zomig, Zyprexa and Zyrtec. FOXBusiness

Astra profits fall on jobs cuts  -  Jan 31, 2008
...in the "low to mid-single digits" this year, although it is braced for further impact from generic competition for its Toprol-XL treatment in the US. The Press Association

AstraZeneca warns of tough market  -  Jan 31, 2008
It said gains from MedImmune would be offset by lower sales in the US of Toprol-XL, a heart drug, which has lost patients to a generic alternative. Financial Times,

Intestinal bleeding requires some care immediately  -  Feb 2, 2008
I was then placed on Toprol XL. After several weeks, I started to get dizzy and lightheaded. I was told to monitor my pressure, which I do. San Gabriel Valley Tribune,

Shell expecting profits rise  -  Jan 25, 2008
Sales of Toprol-XL, a treatment for angina, heart failure and high blood pressure, dived 43% in the third quarter, after generic competition launched in The Press Association

AstraZeneca’s 2007 earnings come in ahead of target  -  Jan 31, 2008
The group booked a sales increase of 7% (at constant exchange rates) to $30 billion, as a drop in US sales of the blood pressure drug Toprol XL (metoprolol) Pharma Times (subscription),

ROUNDUP AstraZeneca's strengthened pipeline fails to impress as ...  -  Jan 31, 2008
...chief financial officer Simon Lowth predicted that revenues from MedImmune would cancel out losses incurred from generic competition to Toprol-XL in 2008. Forbes,

Special kind of back arthritis usually appears in men's 20s  -  Jan 26, 2008
DONOHUE: I am 77 and have taken Toprol-XL for five years. Last year my blood sugar was raised — 6.2, 6.3. When it reached 6.4, my doctor sent me to an SouthCoastToday.com,

AstraZeneca PLC, Fourth Quarter and Full Year Results 2007  -  Jan 31, 2008
The inclusion of MedImmune more than offset the decline in Toprol-XL™ sales in the US. Reported sales in the US were up 8 percent. PharmaLive.com (press release),

Increase in Generic Fill Rate Saved Upstate New York More Than ...  -  Jan 10, 2008
...“In 2007 there were several significant brand name drugs that became available in a generic form, including Norvasc and Toprol XL for high blood pressure ReadMedia (Press Release),

Drugs and Treatments - Toprol XL Oral  -  Nov 5, 2007
If you have chest pain (angina) or heart disease (eg, coronary artery disease, ischemic heart disease, high blood pressure), do not stop using this drug WebMD

Consumers dispute FDA claims about generic drugs  -  Nov 6, 2007
MC wrote to tell us: "My doctor prescribed Toprol-XL several years ago to control hypertension. All went well. Last week my pharmacist refilled my Asbury Park Press,

astrazeneca Q3 2007 Earnings Call Transcript  -  Nov 1, 2007
We faced generic competition across the entire dosage range for Toprol-XL in the US beginning in August, so that certainly affected the top line performance Seeking Alpha,

astrazeneca Third-Quarter Net Falls 15% on Generics (Update4)  -  Nov 1, 2007
...astrazeneca confirmed its 2007 earnings target of $3.60 to $3.75 a share, excluding sales of Toprol XL and restructuring costs. Restructuring costs for the Bloomberg

astrazeneca hit by generic challenge to Crestor  -  Nov 1, 2007
...astrazeneca is expected to unveil earnings of 85.4 cents on a reported basis, including amortization charges, Toprol XL and restructuring costs, Washington Post,

'Big five' still selling well as astrazeneca posts steady results  -  Nov 2, 2007
...astrazeneca’s earnings for the third quarter have been hit hard bygeneric competition to Toprol XL and charges but the Anglo-Swedishdrugmaker can take Pharma Times (subscription),

astrazeneca's earnings fall even as sales rise  -  Nov 1, 2007
...astrazeneca authorized a generic drug company to sell a generic version of its Toprol-XL high-blood pressure drug. “We’re cooperating and providing all the The News Journal,

Medco survey: drug costs hurt savings  -  Nov 13, 2007
...of some generic medications, including versions of the popular high blood-pressure treatments Toprol XL and Coreg, as well as strong mail-order volume. BusinessWeek

Astra profits hit by cheaper rivals  -  Nov 1, 2007
Sales of Toprol-XL, a treatment for angina, heart failure and high blood pressure, dived by 43% in the quarter, after generic competition launched in August The Press Association

Medco Health 3Q Profit Up 16 Percent  -  Nov 1, 2007
The jump in net income reflected the early release of certain generic medications, including a generic version of high blood-pressure treatment Toprol XL, Forbes,

Astra's Crestor faces generic threat  -  Nov 1, 2007
...full-year targets for underlying earnings per share in the range of $3.60 to $3.75, excluding restructuring costs and US sales of heart drug Toprol XL. Reuters UK,

astrazeneca's net skids; 2007 target affirmed  -  Nov 1, 2007
This forecast excludes restructuring costs and the US contribution from Toprol-XL, the company said. Shares of astrazeneca inched up 0.5% in London trading. MarketWatch

astrazeneca beats pretax estimates, delays restructuring costs UPDATE  -  Nov 1, 2007
Its target for earnings per share remains in the range of 3.60 usd to 3.75 usd, excluding restructuring costs and the US contribution from Toprol XL. Hemscott,

Generic drugs give Medco earnings a lift  -  Nov 1, 2007
The generic version of the blood pressure medicine Toprol XL and a growing number of generics purchased through the Medicare Part D prescription plan also The Star-Ledger - NJ.com,

Astra falls as generic threat overshadows results  -  Nov 1, 2007
...but the firm said its target EPS remains in the range of $3.60 to $3.75, which excludes restructuring costs and the US contribution from Toprol-XL. ShareCast,

astrazeneca PLC: Third Quarter and Nine Months Results 2007  -  Nov 1, 2007
Excluding US sales of Toprol-XL™ from the current and the prior year quarter, sales increased 9 percent. The inclusion of medimmune increased sales 2 PharmaLive.com (press release),

Stocks Plunge In Broad Sell-Off  -  Nov 1, 2007
Medco MHS credited a generic version of blood pressure drug Toprol XL and high mail-order volume. Medco makes more money on generics than branded drugs. CNNMoney.com

Medco Health 3Q Profit Up 16 Percent  -  Nov 1, 2007
Medco managers credited the early release of some generic medications, including versions of the popular high blood-pressure treatments Toprol XL and Coreg, Houston Chronicle,

Fitch Affirms Watson Pharmaceuticals's IDR at 'BBB-'; Outlook Stable  -  Oct 29, 2007
The generic pipeline includes copies of Concerta; Toprol-XL (50mg); Cardizem LA; Lovenox (with Amphastar), and Prilosec delayed-release. Business Wire (press release),

astrazeneca celebrates Crestor approval for atherosclerosis  -  Nov 9, 2007
...a vital earner as the firm suffers a slowdown in sales to the generic threat to drugs such as the blood pressure treatment Toprol XL (metoprolol). Pharma Times (subscription),

poised to change the guidelines on perioperative use of beta blockers?  -  Nov 7, 2007
...(CR) beta blocker metoprolol (Toprol XL, astrazeneca) in patients undergoing noncardiac surgery has shown that although the drug reduced the risk of MI, TheHeart.Org,

AHA: Surgery with Beta-Blockers Onboard May Be Risky  -  Nov 7, 2007
Perioperative metoprolol (Lopressor, Toprol-XL) started two to four hours before surgery prevented 15 mis, three revascularizations, and seven atrial MedPage Today,

Global Investing Roundup  -  Nov 1, 2007
This helped offset the drop in sales of such other key drugs such as Nexium and Toprol XL. According to an Associated Press report, astrazeneca Chief Money Morning

astrazeneca Struggles Against Generics  -  Nov 1, 2007
Toprol-XL, another cardiovascular treatment, is already paying the consequences of the full launch of generic competition in the US market. The Business Magazine,

Novartis delivers record earnings in first nine months of 2007  -  Oct 19, 2007
...and ondansetron (Zofran®)[1] as well as generics of the difficult-to-make products metoprolol succinate ER (Toprol-XL®)[1] and cefdinir (Omnicef®)[1]. Prdomain Business Register (press release),

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Buy Drugs Without Prescription. Safe and Secure Ordering.  -  Oct 3, 2007
...diabetes and toprol, toprol xl anxiety, toprol xl generic, medication toprol xl, side effects of toprol xl medication, substitution for toprol xl 25mg, LIVE-Wintersport.com,

Business news in brief  -  Oct 5, 2007
US sales of Toprol-XL contributed $670 million, or 27 cents a share, in the first six months of 2007 to London-based AstraZeneca's revenue. The News Journal,

News published by Sandoz officials updates activities.  -  Oct 4, 2007
Judge Rodney Sippel invalidating patent protection on Toprol XL(R), a beta blocker used to treat angina, heart failure, and high blood pressure. Therapeutics Daily (subscription) (press release),

21st Annual Report: Belt tightens on big pharma  -  Sep 17, 2007
...expected to lose patent exclusivity in 2007, including the widely prescribed sleep medication Ambien and the antihypertensives Norvasc and Toprol-XL. Med Ad News (subscription),

Biotech holds the cards  -  07 Sep 2007
...including sleep medication Ambien and hypertension drugs Norvasc and Toprol XL, according to a report by Medco Health Solutions,Inc. and based on the Business Gazette,

Premera Celebrates Rising Generic Drug Usage; Offers Cutting-Edge ...  -  Aug 22, 2007
This rate is expected to continue climbing with generic versions of blockbuster medications like Ambien, Norvasc and Toprol-XL becoming available in 2007. Insurance News Net,

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