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Toprol-XLThis page contains recent news articles, when available, and an overview of Toprol-XL but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.Overview: Toprol-XL (when available) Metoprolol, a competitive, beta1-selective (cardioselective) adrenergic antagonist, is similar to atenolol in its moderate lipid solubility, lack of intrinsic sympathomimetic activity (ISA), and weak membrane stabilizing activity (MSA). For the treatment of hypertension and angina pectoris Mechanism Of Action: Like betaxolol and atenolol, metoprolol competes with adrenergic neurotransmitters such as catecholamines for binding at beta(1)-adrenergic receptors in the heart and vascular smooth muscle. Beta(1)-receptor blockade results in a decrease in heart rate, cardiac output, and blood pressure. News Articles on Metoprolol Watson Says FDA May Approve Generic Toprol-Xl Soon - Aug 7, 2009 Approval of generic Toprol-XL (metoprolol succinate) in 25- and 50-mg strengths may come first, and the company expects FDA approval for the 100- and 200-mg FDA news (subscription) Par reports 2Q profit on generic Toprol sales - Aug 4, 2009 Par's revenue included $306 million in sales of generic Toprol XL, or metoprolol. The company makes the authorized generic version of the product, Forbes Some points to ponder in considering Obamacare - Aug 28, 2009 Why did the Department of Veterans Affairs reject my prescription for Toprol XL while an evil, greedy, private insurance company provided 17 refills without Cape Cod Times Watson's Metoprolol Could Hurt Par Pharmaceutical - Aug 26, 2009 Par Pharmaceuticals has generated substantial revenues from its Metoprolol succinate ER (Toprol-XL®) product over the past year. In fact, the generic drug Sumfolio.com Toprol OK's a boon for Watson amid shortage - Aug 4, 2009 Watson Pharmaceuticals could reap big benefits from the approval of its version of the blood pressure med Toprol XL, because two rival generic drugs were FiercePharma Guest column: Poison center saves much anxiety - Aug 7, 2009 I took Toprol XL by mistake. I was supposed to take it once a day, and I had taken one that morning. I attempted to contact my cardiologist and had to leave Shreveport Times Pharmacutical downgraded to "above average" - Aug 6, 2009 Pharmacutical's results were driven by higher-than-expected sales of generic Toprol XL and Imitrex, the analysts say. The company is expected to increase newratings.com Fitch Rates Watson Pharmaceuticals' Proposed Sr. Unsecured Notes ... - Aug 18, 2009 ...including generic Toprol XL, the recently launched Gelnique and Rapaflo, and several pending patent challenges with exclusivity such as Mucinex D. Earthtimes (press release) 阿斯利康五大产å“?ä¾?然畅销 - Aug 14, 2009 ...该公å?¸çš„五项主è¦?产å“?(Crestorã€?Nexiumã€?Seroquelã€?Symbicort å’ŒArimidex)å? 了该公å?¸ä¸Šå?Šå¹´æ€»é”€å”®é¢?的一å?Šä»¥ä¸Šï¼Œå…¶ä¸èƒ†å›ºé†‡ç±»è?¯Crestor和心血管类è?¯Toprol XL销售 新浪网 Лучше, чем ожидалоÑ?ÑŒ: «AstraZeneca» объÑ?влÑ?ет результаты за ІІ кв. - Aug 5, 2009 Мировые продажи блокатора бета-адренорецепторов Ñ? пролонгированным выÑ?вобождением Seloken/Toprol-XL/Топрол-XL (метопролола Ñ?укцинат) повыÑ?илиÑ?ÑŒ более чем на Аптека online WORDS TO LIVE BY FOR YOUR - Jun 18, 2009 For people whose doctors have prescribed a beta-blocker called TOPROL-XL or its generic formulation, metoprolol succinate extended-release tablets, North American Press Syndicate Generic drugs come under scrutiny - Jun 23, 2009 Readers of this column have noted some apparent differences in quality among generic drugs: "I was prescribed Toprol-XL 50 mg for high blood pressure and an Pottstown Mercury Caraco cuts half its workforce on production stoppage - Jul 6, 2009 L) blood pressure medicine Toprol XL, resulting in a better-than-expected sales of the branded drug. Last year, bigger players in the space, like Novartis Reuters AstraZeneca's Pipeline Must Deliver - Jun 29, 2009 The company is facing a number of challenges as it enters 2009, most notably generic competition to Toprol-XL, Nexium, Casodex and Pulmicort. Seeking Alpha Soy milk may be key to sex problem - Jul 7, 2009 They include diuretics like hydrochlorothiazide and beta blockers such as atenolol (Tenormin) and metoprolol (Toprol-XL). Since your medicine is controlling Hartford Courant Generic drugs industry is damaged by quality fears - Jul 3, 2009 Earlier this year, AstraZeneca had a sales boost to its blood pressure drug Toprol XL when one of its generic rivals was criticised by the US watchdog the This is London Zacks Analyst Blog Highlights: AstraZeneca, Darden Restaurants ... - Jun 29, 2009 The company is facing a number of challenges as it enters 2009, most notably generic competition to Toprol-XL, Nexium, Casodex and Pulmicort. Earthtimes (press release) Glädjedatum pÃ¥ gÃ¥ng för Astrazeneca - Jun 23, 2009 Konkurrenter har i USA avvaktat med att lansera lÃ¥gpriskopior pÃ¥ Astrazenecas läkemedel Toprol XL mot högt blodtryck. Det gäller även lÃ¥gpriskopior pÃ¥ Realtid.se AstraZeneca Expands Supply of Brand Toprol-XL - Apr 17, 2009 AstraZeneca has ramped up production of its beta-blocker Toprol-XL and is removing certain restrictions it established for purchases of the drug because FDA news (subscription) FDA Safety Changes: Toprol XL, Revlimid, Fludara - Apr 15, 2009 On February 12, the FDA approved safety labeling revisions for metoprolol succinate (Toprol-XL extended-release tablets; AstraZeneca LP) to provide Medscape AstraZeneca a Hold for Now - Apr 13, 2009 The company is facing a number of challenges as it enters 2009, most notably generic competition to Toprol-XL, Nexium, Casodex and Pulmicort. Zacks.com Shortage of pain-relief drug hits region - Apr 13, 2009 Current drug shortages include two popular cardiac drugs, Toprol XL and Indur, causing cardiologists and heart patients to scramble in recent months to find Pittsburgh Post Gazette Orbus Announces Signing Of Anda Development, Manufacturing and ... - Mar 30, 2009 The product is a generic form of Astra Zeneca's branded product, Toprol XL, which had annual sales in the United States of approximately $2.3 billion in FOXBusiness Zacks Analyst Blog Highlights: Lattice Semiconductor, Moog Inc ... - Apr 14, 2009 The company is facing a number of challenges as it enters 2009, most notably generic competition to Toprol-XL, Nexium, Casodex and Pulmicort. Business Wire (press release) Zacks Analyst Blog Highlights: Lattice Semiconductor, Moog Inc ... - Apr 14, 2009 The company is facing a number of challenges as it enters 2009, most notably generic competition to Toprol-XL, Nexium, Casodex and Pulmicort. Trading Markets (press release) The People's Pharmacy - Mar 4, 2009 The doctor prescribed Coumadin and Toprol XL. I would like to... By Joe Graedon and Teresa Graedon‚ Ph.D. Q: I was recently diagnosed with an irregular Seattle Times Goldman reaffirms 'Sell' rating on Watson - Mar 3, 2009 ..."Solid management execution and anticipation over approval of generic Toprol XL have led shares 6 percent higher against a 19 percent decline in the S&P 500 MSNBC AstraZeneca Filling Supply Gap For Blood Pressure Drug - Feb 20, 2009 Last year, Sandoz, the generic unit of Novartis AG (NVS), recalled 6 million bottles of generic Toprol XL after the Food and Drug Administration sent a EasyBourse.com Recall of generic blood-pressure drug causing confusion - Mar 2, 2009 A recall on the generic version of the popular blood-pressure medication Toprol XL has worried patients calling local pharmacies looking for answers. Canton Repository (subscription) Drug recall leaves shortage of prescriptions - Feb 26, 2009 ETHEX Corp. recalled dozens of drugs recently as a precautionary measure, including the generic form of the blood pressure medicine Toprol XL that it KTKA.com Watson Pharmaceuticals Reports Fourth Quarter and Full Year 2008 ... - Feb 20, 2009 This forecast includes only a modest contribution from Watson's sales of generic Micro-K(R) and generic Toprol XL(R). Due to production issues experienced Lifescience-online Watson 4th-qtr profit, 2009 view top expectations - Feb 19, 2009 ...products remain similar and should Watson gain timely approval for one of the products, a generic version of AstraZeneca Plc's heart drug Toprol XL. Alibaba News Channel Metoprololo nell'ipertensione pediatrica - Feb 22, 2009 Toprol-XL Pediatric Hypertension Investigators. Efficacy and Safety of Extended Release Metoprolol Succinate in Hypertensive Children 6 to 16 Years of Age: Pillole.org Toprol-XL Competitors Hampered by Production Issues - Feb 2, 2009 AstraZeneca is the only drug company manufacturing its former blockbuster hypertension treatment Toprol-XL because compliance issues related to good FDA news (subscription), Generic Toprol XL Scarce, After Problems at Novartis and KV - Jan 28, 2009 If you take generic Toprol XL for high blood pressure, you may have noticed it’sa little hard to come by these days. AstraZeneca is boosting production of Wall Street Journal Blogs, Metoprolol Succinate Recalled: Brand Name Drug Scarce But Still ... - Jan 30, 2009 The original, brand name version, Toprol XL, is in very low supply. PharmacyChecker.com finds that consumers can obtain Toprol XL from licensed pharmacies PR Web (press release), US shortage of blood pressure drug affects Tulsans - Jan 31, 2009 She was told the warehouse hadn't shipped new supplies of the generic version of Toprol XL she needed. But she wasn't told why. "Seven days went by, Tulsa World, Manhattan Research Releases Top Pharma Brand Product Sites by ... - Feb 3, 2009 Singulair, Strattera, Tamiflu, Topamax, Toprol XL, TriCor, Valtrex, Viagra, Vytorin, Wellbutrin XL, Yasmin, Yaz, Zocor, Zoloft, Zomig, and Zyprexa. PR Web (press release), MedImmune boosts AstraZeneca profits - Jan 29, 2009 The company was hit by soaring sales of competing generic versions of its Toprol-XL drug, which rung up 70 percent fewer sales in the United States from Bizjournals.com, Clearing the record - Jan 31, 2009 Toprol XL is used to treat hypertension and angina, not depression. A Business story yesterday about HF (Gerry) Lenfest's charitable giving incorrectly Philadelphia Inquirer, Correction: KV Pharmaceutical recall - Jan 29, 2009 28 story about KV Pharmaceutical Co., The Associated Press erroneously described Toprol XL as an antidepressant. It is used to treat hypertension and The Associated Press KV Pharmaceutical recalls dozens of drugs - Jan 28, 2009 Products named in the recall include generic versions of the antidepressant Toprol XL, hypertension drugs Norvasc and Cardura, a variety of painkillers International Herald Tribune, Market Report -- Short Stories (WPI) - Jan 22, 2009 Stanford Research upgrades WPI to Buy from Hold and sets target price at $31, based on a new opportunity in generic Toprol XL competitive landscape, MSN Money Can sex cause a heart attack? - Jan 16, 2009 ...not to my heart medications," says Saldana, who was on the beta-blocker Toprol-XL (metoprolol) before suffering a heart aneurysm in July. CNN KV, Novartis problems spawn drug shortage; UK starts stockpiling ... - Jan 29, 2009 Generic Toprol XL, a treatment for high blood pressure, is in short supply after manufacturing problems at Novartis and KV Pharma--two big suppliers in the FiercePharma, AstraZeneca 4Q Net Profit $1.25 Billion, Targets $5.15-$5.45 '09 ... - Jan 29, 2009 Sales in the US were up 3%, as the adverse impact from generic competition for Toprol-XL is now annualised. Sales in the Rest of World were up 5%. EasyBourse.com, BREAKING NEWS: Sales rise but more job cuts at AstraZeneca - Jan 29, 2009 In geographic terms, US sales were up 3%, despite the erosion of revenues from the blood pressure drug Toprol XL/Seloken (metoprolol), which has suffered Pharma Times, AstraZeneca: BPA 2008 'en ligne' de 5,10 dollars. - Jan 29, 2009 ...l'effet de l'arrivée d'un générique de son traitement de la pression artérielle, Toprol-XL, étant désormais effacé. 'AstraZeneca a délivré une solide BFM radio, December 2008 Mayo Clinic Health Letter Highlights: Colorectal ... - Dec 9, 2008 ...legs syndrome -- Toprol-XL (metoprolol succinate) for blood pressure, heart failure and angina -- Zyrtec-D (cetirizine/pseudoephedrine) for allergies. MarketWatch Letter: Wide prescription choice requires intelligent study - Nov 30, 2008 However, many drugs in this tier have a full price that is less than $95, such as Hyzaar, $87; Fosamax, $78; Xalatan, $69; and Toprol XL, $29. TCPalm, Generic Drugs are as Good as Brand Names for Heart Problems - Dec 2, 2008 A long-acting beta-blocker metoprolol also worked as well as brand-name Toprol XL. And Zocor, a statin used to reduce cholesterol, performed no better than HealthNewsDigest.com, Double Trouble for AstraZeneca - Nov 20, 2008 Losing heartburn medication Prilosec, beta blocker Toprol-XL, and now Pulmicort Respules to generic competition wouldn't be so bad if the company wasn't Motley Fool AstraZeneca posts 29% profit rise - Oct 30, 2008 Sales in the US overall were flat in the quarter as the company also integrated a sharp drop in sales of cardiovascular drug Toprol-XL. Toprol-XL quarterly MarketWatch KV takes 2Q loss on sliding sales and higher costs - Nov 17, 2008 Metoprolol is a generic version of AstraZeneca (nyse: AZN - news - people )'s drug Toprol XL. Overall, revenue from KV's Ethex brand products, which include Forbes, Astra lifts earnings target - Oct 30, 2008 ...non-US business offsetting flat growth in America after its high blood pressure treatment Toprol-XL was hit by competition from cheaper generic rivals. The Press Association AstraZeneca reports sizable jump in profits - Oct 30, 2008 ...which the company attributed to a $141 million decline in sales of its blood pressure drug Toprol-XL due to generic competition. The News Journal, Drug to Protect Surgery Patients Causes Strokes - Nov 17, 2008 Some of the most widely prescribed beta-blockers include atenolol (Tenormin), metoprolol (Lopressor, Toprol-XL) and propranolol (Inderal, Inderal LA) . Natural News.com, AstraZeneca goes on the hunt - Oct 30, 2008 Sales of the Toprol-XL treatment for hypertension, for instance, dropped $141m as a result of competition from generic versions. guardian.co.uk, Astrazeneca shares up on higher earnings expectation - Oct 30, 2008 In the USA, sales of high blood pressure treatment Toprol-XL fell by £85.5m after cheaper generic rivals came on the market. Astrazeneca, which employs 6500 Crain's Manchester Business, AstraZeneca reports strong third quarter - Oct 31, 2008 A $141 million loss of Toprol XL (metoprolol succinate) sales to generic competition counteracted the 5% increase in the rest of the US business Scrip World Pharmaceutical News (subscription), AstraZeneca 3Q profits up 29 percent - Oct 30, 2008 ...where the company is facing tough generic competition to its products were unchanged as a $141 million decline in sales of Toprol-XL overshadowed 5 The Associated Press Zacks Analyst Blog Highlights: Pride International, Lexicon ... - Nov 4, 2008 AstraZeneca Plc (NYSE: AZN) is facing a number of challenges, most notably from generic competition to Toprol-XL and Nexium. Management is determined to Business Wire (press release), Zacks Analyst Blog Highlights: Pride International, Lexicon ... - Nov 4, 2008 AstraZeneca Plc (NYSE: AZN | Quote | Chart | News | PowerRating) is facing a number of challenges, most notably from generic competition to Toprol-XL and Trading Markets (press release), 阿斯利康第三å£ç›ˆåˆ©å¢žé•¿29% - Oct 30, 2008 ...ä¸?过,å?—心血管è?¯ç‰©Toprol-XL 新浪网, 阿斯利康第三å£ç›ˆåˆ©å¢žé•·29% - Oct 30, 2008 ...ä¸?é?Žï¼Œå?—心血管藥物Toprol-XL 新浪網, Sandoz Gets Warning Letter for Generic Toprol XL Production Operations - Sep 26, 2008 The FDA is questioning a decision by Novartis subsidiary Sandoz to continue distributing generic versions of Toprol XL after it found the company did not FDA news (subscription), Sandoz Factory Cited in South Africa - Oct 17, 2008 NC, facility for various GMP deficiencies, including inadequate validation of the production process for generic Toprol XL (metoprolol succinate). FDA news (subscription), Brand Names/Synonyms: Toprol-XL is also known by the following brand names and/or synonymsBeloc; Betaloc; CGP 2175; H 93/26; H-23/96; LOPRESSOR HCT; Lopresor; Lopresoretic; Lopressor; Metoprolol; Metoprolol Tartrate; Metroprolol; Prelis; Selo-Zok; Seloken; Selopral; Toprol; Toprol-Xl Drug Category: Toprol-XL is categorized under the following by the FDA: Sympatholytics; Antihypertensive Agents; Antiarrhythmic Agents; Adrenergic Agents; ATC:C07AB02; ATC:C07AB52 Dosage Forms: Tablets Absorption: rapid and complete, 50% Interactions: Interactions for Metoprolol: Catecholamine-depleting drugs (e.g., reserpine) may have an additive effect when given with beta-blocking agents. Patients treated with extended release metoprolol succinate plus a catecholamine depletor should therefore be closely observed for evidence of hypotension or marked bradycardia, which may produce vertigo, syncope, or postural hypotension. Chemical IUPAC Name: 1-[4-(2-methoxyethyl)phenoxy]-3-(1-methylethylamino)propan-2-ol : |
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