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TigecyclineThis page contains recent news articles, when available, and an overview of Tigecycline but does not offer medical advice. You should contact your physician with regard to any health issues or concerns....being hotly contested by currently marketed products (eg Wyeth's Tygacil (tigecycline), Cubist's Cubicin (daptomycin) and Pfizer's Zyvox (linezolid)), Pharmaceutical Business Review Nontuberculous Mycobacterial Infections - Aug 30, 2008 Additional testing for newer agents such as linezolid, moxifloxacin, and tigecycline can be considered, although there is little clinical experience with RedOrbit, Rib-X Initiates Phase II Skin Infection Trial - Jul 16, 2008 The study's primary endpoint is the assessment of RX-3341 efficacy, safety and tolerability at the two different doses compared to that of tigecycline's RedOrbit, Rib-X Pharmaceuticals Initiates Phase 2 Trial For RX-3341 In ... - Jul 16, 2008 The study's primary endpoint is the assessment of RX-3341 efficacy, safety and tolerability at the two different doses compared to that of tigecycline's Medical News Today (press release), Diabetic Foot Infection - Jul 15, 2008 The efficacy and safety of tigecycline in the treatment of skin and skin-structure infections: results of 2 double-blind phase 3 comparison studies with RedOrbit, Basilea: ceftobiprole wins first regulatory approval - Jul 2, 2008 ...pathogens have been introduced in the past few years, including linezolid (Zyvox), daptomycin (launched in 2003) and tigecycline (launched in 2005). Pharmaceutical Business Review TYGACIL Approved For Treatment of Patients with Community-Acquired ... - 02 Jun 2008 Wyeth Pharmaceuticals has announced that the FDA has issued an approvable letter for the first-in-class antibiotic TYGACIL (tigecycline) for the treatment Pharmaceutical Processing, Wyeth Receives Approvable Letter from FDA for TYGACIL for the ... - May 29, 2008 The two studies (N=418, N=434) were conducted at 116 sites in 28 countries across the globe and evaluated the efficacy and safety of tigecycline compared PR Newswire (press release), Wyeth Withdraws European Application For Tygacil - 23 Apr 2008 ...a unit of Wyeth (WYE), is withdrawing its application for an extension to the European Marketing Authorization for Tygacil, or tigecycline. CNNMoney.com More Clinical Data Required to Support European Approval of CAP ... - 23 Apr 2008 ...announced today that it is withdrawing its application for an extension to the European Marketing Authorization for TYGACIL(R) (tigecycline). CNNMoney.com (press release) The incorrigible bugs - Apr 3, 2008 Other available drugs for such resistant bacteria are daptomycin (Cubist Pharma) and tigecycline (Wyeth Labs). However, resistance has been now also been Express Pharma, Methicillin-resistant Staphylococcus aureus in the Community and ... - Apr 9, 2008 ...[29] Likewise, a trial of tigecycline, which is approved for intraabdominal and skin infections, failed to meet the study's primary endpoint in Medscape (subscription) Treatment of Acute and Chronical Bacterial Prostatitis Caused by ... - Apr 8, 2008 ...oxazolidinones (linezolid), carbapenems (LY 333328 ie Oritavancin )(11), everninomicins (SCH 27899) (12) , and glycylcyclines ( tigecycline ie GAR-936 ScienceBlog.com, Targanta Announces Highlights of Oritavancin Data to Be Presented ... - Apr 18, 2008 ...vancomycin, moxifloxacin, linezolid and tigecycline) against an SCV strain that was isolated from a cystic fibrosis patient in a human airway model, StreetInsider.com (subscription), Wyeth Reports Earnings Results for the 2007 Fourth Quarter and ... - Jan 31, 2008 New Drug Application for its first-in-class antibiotic TYGACIL (tigecycline) for the treatment of patients with community- acquired pneumonia. FOXBusiness Wyeth braces itself for earnings slip in 2008 due to generics - Feb 1, 2008 Nevertheless, Wyeth still has high hopes for its pipeline and expects its first-in-class antibiotic Tygacil (tigecycline), for the treatment of patients Pharma Times (subscription), New Report Explores New Drug Innovation and the Strategy to Combat ... - Jan 21, 2008 Whilst these remain important first-line antibiotics and others such as Vancomycin and more recently Zyvox (Pfizer), Tigecycline (Wyeth) and Daptomycin Business Wire (press release), Drug Resistant Infections - Nov 14, 2007 It's called Tigecycline, an IV drug that's part of the Tetracycline family. The second antibiotic is called Telavancin. They couldn't come soon enough. XETV FOX6 San Diego, Wyeth seeks OK to market Tygacil for pneumonia - Oct 24, 2007 Tygacil, whose chemical name is tigecycline, was approved in mid-2005 for treatment of intra-abdominal infections and complicated skin and skin structure Reuters FDA Accepts Wyeth's Supplemental New Drug Application for Tygacil ... - Oct 24, 2007 Anaphylaxis/anaphylactoid reactions have been reported with nearly all antibacterial agents, including tigecycline, and may be life threatening. CNNMoney.com FDA Accepts Wyeth’s Supplemental New Drug Application for Tygacil - Oct 24, 2007 Study data showed Tygacil (tigecycline) cured 89.7 percent of patients while levofloxacin, an existing treatment option for CAP, cured 86.3 percent. FDA news (subscription), Tougher than MRSA, they beat most drugs - Nov 7, 2007 Tigecycline, approved two years ago, was developed by Wyeth specifically to attack a range of drug-resistant bacteria. But the toughest strains appear to Philadelphia Inquirer, Patients might avoid surgeries - Nov 2, 2007 Tigecycline came out 91 percent effective against many of those bacteria and another class of bacteria that also includes some of the most difficult to Augusta Chronicle (subscription), Staph bacteria resists medicines - Oct 31, 2007 Today we have a variety of antibiotics that effectively treat these MRSA, including linezolid, tigecycline, daptomycin, vancomycin and often clindamycin and Aiken Standard (subscription), FDA accepts Wyeth's Tygacil snda for review - Oct 25, 2007 Study data showed that Tygacil (tigecycline) cured 89.7% of patients hospitalized with community-acquired pneumonia (CAP), and levofloxacin, Trading Markets (press release), Astellas/Theravance: FDA delays telavancin approval - Oct 25, 2007 Telavancin is targeting an already crowded market dominated by established competitors including Pfizer's Zyvox (linezolid), Wyeth's Tygacil (tigecycline) Pharmaceutical Business Review FDA Accepts Wyeth's Supplemental New Drug Application for Tygacil ... - Oct 24, 2007 Application (snda) for its first-in-class antibiotic Tygacil(R) (tigecycline) for the treatment of patients with community-acquired pneumonia (CAP). PharmaLive.com (press release), Over-prescribing boosts superbugs - Oct 20, 2007 Ohio State is working to limit doctors' use of nine antibiotics, including Colistin, Tigecycline and Aztreonam. Physicians who want to prescribe any of the Columbus Dispatch, Selecting Anti-infective Agents for the Treatment of Bone ... - Oct 11, 2007 Tigecycline (Tygacil; Wyeth, Madison, NJ) is the only currently available member of the glycylcycline class of antimicrobials, a class that is structurally Ortho SuperSite, Deadly mystery disease follows troops home - Oct 7, 2007 It took doctors about two weeks to narrow down his treatment to a relatively new intravenous antibiotic, tigecycline. Doctors operated on him nearly every San Francisco Chronicle, Research and Markets: Antibiotics and Drug Resistance 2007 - Drug ... - Aug 20, 2007 Whilst these remain important first-line antibiotics and others such as Vancomycin and more recently Zyvox (Pfizer), Tigecycline (Wyeth) and Daptomycin Business Wire (press release), Wyeth to File for FDA Approval of Tygacil for the Treatment of ... - Jul 6, 2007 PharmaLive.com (press release),Anaphylaxis/anaphylactoid reactions have been reported with nearly all antibacterial agents, including tigecycline, and may be life-threatening. Wyeth to File for FDA Approval of Tygacil for the Treatment of ... - 06 Jul 2007 PharmaLive.com (press release),Anaphylaxis/anaphylactoid reactions have been reported with nearly all antibacterial agents, including tigecycline, and may be life-threatening. Need for new drugs to tackle 'superbugs' - Jun 7, 2007 Pharmaceutical Business ReviewHowever, the MRSA market is likely to become increasingly crowded with drugs such as daptomycin, launched in 2003, tigecycline, launched in 2005, Tygacil to take a shot at drug-resistant bacterial infections - Jun 22, 2007 Livemint,The drug, known as Tigecycline in generic terms, is indicated for use in complicated drug-resistant bacterial skin infections and complicated Astellas Pharma: telavancin enters EU battle for MRSA market share - May 2, 2007 Pharmaceutical Business Review...shows limited tissue penetration and requires patient monitoring but dosed once daily) and Wyeth’s Tygacil (tigecycline, good empiric activity apart Efficacy of Tigecycline Compared to Levofloxacin for Treating ... - Apr 5, 2007 DG NewsFurther, in the patients with CAP and Streptococcus pneumoniae bacteraemia, tigecycline achieved clinical cure rates similar to those seen in GSK meet no resistance for new antibacterial - Apr 16, 2007 DrugResearcher.com,In recent months, new antibiotics from the likes of Wyeth (Tygacil; tigecycline) Pfizer (Zyvox; linezolid) and Novartis/Cubist (Cubicin; daptomycin) have Scientific Results Presented at ECCMID Demonstrate Well ... - Apr 5, 2007 WebWire (press release),In vitro activity of ceftobirpole, dalbavancin and tigecycline against methicillin-resistant Stahpylococcus aureus strains from hospital patients in Belgium Scientific Results Presented At ECCMID Demonstrate Well ... - Apr 3, 2007 PharmaLive.com (press release),P784 In vitro activity of ceftobiprole, dalbavancin and tigecycline against methicillin-resistant Staphylococcus aureus strains from hospitalised patients Scientific Results Presented At ECCMID Demonstrate Well ... - Apr 2, 2007 Primenewswire (press release),D. Balis, R. Strauss, B. Murthy, H. Tiian, G. Noel (Raritan, US) P784 In vitro activity of ceftobiprole, dalbavancin and tigecycline against Antibacterials: narrow-spectrum strategy could change market - Mar 29, 2007 Pharmaceutical Business ReviewSince the majority of more recently introduced hospital antibacterials are broad spectrum agents - such as Wyeth's Tigecycline and Cubist/Novartis' Wyeth kicks off CMO agreement with Crucell - Dec 20, 2006 OutSourcing-Pharma.com,Prevnar (Pneumococcal 7-valent Conjugate Vaccine) for the prevention of serious pneumococcal diseases in young children, and Tygacil (tigecycline IV) a Superbug Warning: New Report Warns MRSA Is Reaching Epidemic ... - Dec 15, 2006 Medical News Today (press release),Tigecycline is one of a limited number of new broad-spectrum antibiotics available in Europe which can be used when the causative bacteria are still unknown.(6 ... Wyeth kicks off CMO agreement with Crucell - Dec 20, 2006 In-PharmaTechnologist.com,Prevnar (Pneumococcal 7-valent Conjugate Vaccine) for the prevention of serious pneumococcal diseases in young children, and Tygacil (tigecycline IV) a new ... Superbug Warning: New Report Warns MRSA is Reaching Epidemic ... - Dec 12, 2006 Earthtimes.orgTigecycline is one of a limited number of new broad-spectrumantibiotics available in Europe which can be used when the causative bacteriaare still unknown.(6). ... Many Diagnostics (eg, Phenotypic Tests, Molecular Tests) Are Now ... Nov 7, 2006 ...use of current drugs? Will it increase or decrease use of drugs such as daptomycin, linezolid, and tigecycline? -- Impact of drug ... -Genetic Engineering News (press release), Foro de Shell Security - Seguridad informática Oct 26, 2006 These oncogenes can be activated by tigecycline chromosomal translocations (ie, the genetic hallmark of lymphoid tikosyn alignancies), or tumor suppressor loci ... -Shell Security, Most infections acquired in ICU, study reveals Sep 14, 2006 ...treatments because of the high cost. This fall, a new antibiotic, tigecycline, will be available in Canada. It has been used in ... -Winnipeg Free Press (subscription) Broad Spectrum Antibiotic Available for Antibiotic Resistant ... 22 Jul 2006 Tygacil (tigecycline)is a new, expanded broad-spectrum IV antibiotic that can be used for the treatment of a wide range of infections including those caused by ... -MedIndia Antibiotic use backed in MRSA fight Jul 11, 2006 The Scottish Medicines Consortium (SMC) is recommending using the antibiotic Tygacil, also known as tigecycline, to treat severe hospital infections. ... -ic Ayrshire.co.uk Scots to get first use of superdrug Jul 11, 2006 A new drug, tigecycline, has been approved by the Scottish Medicines Consortium for use in patients who do not respond to more common antibiotics. ... -Glasgow Evening Times Dr. George Ellestad Receives ACS Medicinal Chemistry Award Jun 28, 2006 This insight was further expanded by the medicinal chemistry team as part of the strategy which led to the discovery of Tygacil® (tigecycline), the first in a ... -Yahoo! News New Broad-spectrum Antibiotic Tygacil* (tigecycline) Receives ... May 4, 2006 Tygacil* (tigecycline) is the first antibiotic in a new class called glycylcyclines approved in Europe. Tygacil is produced by Wyeth ... - Medical News Today New Broad-spectrum Antibiotic Tygacil (tigecycline) Receives ... May 3, 2006 MAIDENHEAD, England, May 2, 2006 – Tygacil* (tigecycline) is the first antibiotic in a new class called glycylcyclines approved in Europe . ... - PharmaLive.com New Broad-Spectrum Antibiotic Tygacil[x] (tigecycline) Receives ... May 2, 2006 Tygacil[x] (tigecycline) is the first antibiotic in a new class called glycylcyclines approved in Europe. Tygacil is produced by ... - PR Newswire UK International Approvals: Tygacil, DepoDur, and Zyvox May 8, 2006 May 8, 2006 — The European Commission has approved tigecycline injection for the treatment of complicated intra-abdominal infections and complicated skin and ... - Medscape (subscription) Natural Products Reemerge May 10, 2006 ...changed. Last June, Wyeth launched Tygacil (tigecycline IV), which Koehn says is a fifth or sixth generation tetracycline. "While ... - Drug Discovery & Development (subscription) (PRN) - RR Donnelley Reports First-Quarter 2006 Results ... [+] May 2, 2006 Obligations ... [+. PRN) - New Broad-Spectrum Antibiotic Tygacil[x] (tigecycline) Receives Approval for Use in Europe Today ... [+. ... - Bolsamania.com Bad Bugs, Few Drugs May 3, 2006 A chilling example is the delay of an injectable antibiotic called Tigecycline, for infections caused by antibiotic-resistant pathogens. ... - TCS Daily Novel antibiotic from Wyeth gets green light in Europe May 3, 2006 Tygacil (tigecycline) has been approved by the European Medicines Agency for use in complicated infections of the skin and soft tissue and complicated intra ... - Pharma Times (subscription) Tigecycline in Vitro Activity Against Often Difficult to Treat ... Apr 4, 2006 NICE, FRANCE -- April 4, 2006 -- The activity of the new glycylcycline antibiotic tigecycline (GAR-936) against a wide spectrum of pathogens shows promise for ... - DG News 11th Annual Antibacterial Drug Discovery & Development Summit ... Mar 24, 2006 Sessions focus on pre-clinical and clinical development, including clinical updates on Dalbavancin from Pfizer, Tigecycline from Wyeth, and Televancin from ... - HTScreening Wyeth Pharmaceuticals' Antibiotic Tygacil (Tigecycline) Receives ' ... Mar 2, 2006 ...today that it has received a "positive opinion" recommending approval for the introduction of its first-in- class antibiotic Tygacil® (tigecycline) to the ... - DG News CMPH - Initial Marketing Authorisation Applications,Europe ... Feb 24, 2006 ...fractures. EMEA review began on 14 March 2005 with an active review time of 224 days. -- Tygacil (tigecycline), Wyeth Europa Ltd. Tygacil ... - Medical News Today, European Medicines Agency: Committee for Medicinal Products for ... Feb 23, 2006 ...fractures. EMEA review began on 14 March 2005 with an active review time of 224 days. Tygacil (tigecycline), Wyeth Europa Ltd. Tygacil ... - PharmaLive.com, Scientists re-engineer antibiotic to counter drug resistance Feb 9, 2006 The product, tigecycline (Tygacil) joins the oxazolidinones, (Pfizer's linezolid) and lipopeptides (Cubist's daptomycin) in a small but growing arsenal against ... - DrugResearcher.com, : |
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