Temazepam

This page contains recent news articles, when available, and an overview of Temazepam but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Temazepam (when available)

Pharmacology and use:
Temazepam is a benzodiazepine used as a hypnotic agent in the management of insomnia. Temazepam produces CNS depression at limbic, thalamic, and hypothalamic levels of the CNS. Temazepam increases the affinity of the neurotransmitter gamma-aminobutyric acid (GABA) for GABA receptors by binding to benzodiazepine receptors. Results are sedation, hypnosis, skeletal muscle relaxation, anticonvulsant activity, and anxiolytic action. For the short-term treatment of insomnia (generally 7-10 days).

Mechanism Of Action:
Benzodiazepines bind nonspecifically to benzodiazepine receptors, which affects affects muscle relaxation, anticonvulsant activity, motor coordination, and memory. As benzodiazepine receptors are thought to be coupled to gamma-aminobutyric acid-A (GABA_A) receptors, this enhances the effects GABA by increasing GABA affinity for the GABA receptor. Binding of the inhibitory neurotransmitter GABA to the site opens the chloride channel, resulting in a hyperpolarized cell membrane that prevents further excitation of the cell.

News Articles on Temazepam

Sleeping pill risks found to outweigh benefits  -  11 Aug 2008
...profile of zolpidem or zopiclone is more favourable than that of short-acting benzodiazepines (such as temazepam)," the NPS position statement says. The Australian,

Suicide GP accepts ban over death drugs  -  Aug 10, 2008
He said she got rid of the pills but seven years later, at 87, overdosed on Temazepam. Kerr prescribed more of the drug and she killed herself 11 days later Glasgow Sunday Mail,

GP gave sleeping pills to suicidal patient  -  Jul 24, 2008
Patient A killed herself in December 2005, aged 87, using a cocktail of Temazepam, antihistamines and painkillers. The GMC heard she made a failed suicide Independent,

Heath Ledger Investigation Closed; Mary-Kate Olsen Won't Have To ...  -  Aug 6, 2008
In addition to Oxycontin and Vicodin, Ledger's autopsy also found the presence of Xanax, Valium, Temazepam and Doxylamine. MTV.com

Doctor 'gave suicidal pensioner sleeping pills'  -  Jul 15, 2008
She later died of an overdose of three other drugs, including a dose of temazepam which the hearing was told he also gave her. Telegraph.co.uk,

Colne dad's confusion over pill dose led to death  -  Aug 8, 2008
...consultant pathologist at Burnley General Hospital, who performed the post-mortem examination, said he found high levels of the drug temazepam and an Pendle Today,

Patient death GP action 'illegal'  -  Jul 17, 2008
And he also criticised Dr Kerr for prescribing his patient with Temazepam, just days after she tried to kill herself with the drug. BBC News,

Mary-Kate Avoids Potential Subpoena  -  Aug 7, 2008
Ledger’s autopsy results found the actor had Oxycontin, Vicodin, Xanax, Valium, Temazepam and Doxylamine present in his system. “Despite tabloid speculation andPOP,

Olympic spirit  -  Jul 31, 2008
BBC commentators are, I suspect, already being force-fed a diet of sugar and temazepam. By the time a Briton comes third in the men's 10m air pistol, New Statesman,

Suicide Pill Row GP Criticised By Expert Hearing Told Doc Was ...  -  Jul 21, 2008
Dr Peter also criticised Dr Kerr for prescribing Patient A with temazepam just days after she tried to kill herself using this medicine. RedOrbit,

The Dark Night: Hollywood and Sleeping Pills  -  Jul 21, 2008
Heath Ledger had Temazepam, Alprazolam, Diazepam, Hydrocodone and Oxycodone (painkillers) and Doxylamine (antihistamine) in his body at the time of his PR Web (press release),

GP 'Said He Was in Euthanasia Society'  -  Jul 17, 2008
Patient A died after taking an overdose, including the sedative temazepam, on December 12, 2005. She had survived a suicide attempt with the same drug less RedOrbit,

Heath Ledger drug investigation 'dropped'  -  Aug 7, 2008
...“Mr Ledger died as the result of acute intoxication by the combined effects of oxycodone, hydrocodone, diazepam, temazepam, alprazolam, and doxylamine," Times Online,

New in Brief  -  Jul 23, 2008
The same ruling was made against the Glasgow GP for failing to refer the retired businesswoman to hospital after she overdosed on Temazepam tablets in Times Online,

Dozens of drug, sex charges dropped for Hot Chocolate Rapist  -  Jul 28, 2008
It is alleged he laced his victim's drinks with Rohypnol, Xanax, Temazepam and other unspecified drugs to knock them out before raping or indecently Melbourne Herald Sun,

Last year, nearly four million Britons used illicit drugs  -  Jul 20, 2008
Maybe eggs - temazepam capsules - which are great for sleeping. But I usually rely on the goodness of doctors. I'm stocked up at the moment, but in a month, guardian.co.uk,

WIFE DRUGGED HUSBAND'S FOOD  -  Jul 30, 2008
Truro Magistrates Court previously heard that after the third incident, Lees told police that she had put the sedative temazepam in his tea. Western Morning News,

So desperate for a good night’s sleep  -  Jul 30, 2008
...“In the past, I have been on triple strength sleeping tablets, diazepam, temazepam, but they didn’t work and, in any event, I don’t want to rely on drugs. Liverpool Echo,

Drug Deaths Soar 360 Percent  -  Jul 28, 2008
A toxicology report found acute intoxication by the combined effects of oxycodone and hydrocodone (painkillers), diazepam (Valium, anti-anxiety), temazepam InjuryBoard.com,

Primary insomnia is a condition on its own  -  Jul 27, 2008
Specific drugs which promote sleep are the benzodiazepines such as temazepam, oxazepam, and lorazepam. Newer drugs (zolpidem in the US; zopiclone and Canoe.ca,

Benzodiazepines-Dangerous Drug Addiction  -  Jul 26, 2008
Shorter-acting benzodiazepines used to manage insomnia include estazolam (ProSom®), flurazepam (Dalmane®), temazepam (Restoril®), and triazolam (Halcion®). TransWorldNews (press release),

Thug Who Escaped Five Rape Charges In Fifteen Months  -  Jul 23, 2008
She claimed he gave her Temazepam, known as jellies and a favourite with junkies, and she was repeatedly raped, forced to perform other sex acts and she got Glasgow Daily Record,

Pro-Life News: British Assisted Suicide, California Abortion ...  -  Jul 21, 2008
Kerr's patient, who had osteoporosis and chronic lower back pain and feared becoming a burden on her family, killed herself using a combination of Temazepam LifeNews.com,

4 Overdoses Since '06 Linked To Doctor  -  Jul 18, 2008
A medical examiner's report found Michael Grogan died of an accidental overdose of morphine, alprazolam, carisoprodol, temazepam and doxepin. Tampa Tribune,

Accidental Overdose Killed Heath Ledger  -  Jul 18, 2008
The cause of death was "acute intoxication by the combined effects of oxycodone, hydrocodone, diazepam, temazepam, alprazolam and doxylamine," a spokeswoman Buzzle,

2008-07-16 17:57:17 - Undiagnosed Sleep Disorder Market Offers ...  -  Jul 16, 2008
Major products are Ambien, Ambien CR, Lunesta, Temazepam, and Zolpidem. Respironics and ResMed are the leading competitors in the continuous positive airway PR-Inside.com (Pressemitteilung),

Consumer Reports Survey: 44% of Americans Are 'Problem Sleepers ...  -  Aug 4, 2008
...aren't necessarily better than older, cheaper drugs such as estazolam or temazepam for many people who need a sleep aid for just a night or two. PR Newswire (press release),

Scozia. Sei mesi di sospensione ad un medico per il suicidio assistito  -  Jul 25, 2008
Poi nel 2005 la visito', dopo che la donna aveva tentato il suicidio, ma non la porto' in ospedale, anzi le prescrisse delle pillole di Temazepam, ADUC Salute,

Mary Kate pide inmunidad antes de declarar a policía sobre muerte ...  -  Aug 7, 2008
...hidrocodona, diazepam, temazepam, alprazolam y doxylamina, una combinación de antidepresivos, analgésicos, ansiolíticos y calmantes. El Universal (Venezuela),

Atriz Mary-Kate Olsen nega ligação com fornecimento de drogas a ...  -  Aug 5, 2008
...morreu acidentalmente intoxicado por um coquetel de seis medicamentos: oxycodona, hidrocodona, diazepam, temazepam, alprazolam e doxylamina, AFP

Heath Ledger a ostatní  -  Aug 3, 2008
Išlo konkrétne o oxycodon, hydrocodon, diazepam, temazepam, alprazolam a doxylamin, �?iže smrteľnú kombináciu liekov na spanie, proti bolesti a prostriedkov SME online,

Esperando a los ídolos  -  Jul 25, 2008
...hidrocodona, diazepam, temazepam, alprazolam y doxylamina, es decir, una combinación de antidepresivos, analgésicos, ansiolíticos y calmantes. El País (España),

Biografía no autorizada del fallecido actor astraliano Heath ...  -  Aug 2, 2008
...fue una intoxicación accidental, resultado del abuso de medicamentos prescritos (oxicodona, hidrocodona, diazepam, temazepam, alprazolam y doxilamina). Impulso Baires,

Joker: Un ser agobiado y siniestro  -  Jul 16, 2008
Una intoxicación accidental resultado del abuso de medicamentos prescritos: oxicodona, hidrocodona, diazepan, temazepam y alprazolam. Vanguardia (México),

Celebrity health: Steve Tyler  -  07 Jul 2008
...prescription drugs dependency while actor Heath Ledger overdosed on a combination of painkillers that included temazepam, doxylamine and diazepam. Irish Independent,

Magistrate as of July 5  -  Jul 5, 2008
At that time he was under the influence of alprazolam, temazepam, cocaine and methadone, according to the report. Lewandowski was stopped the second time by Daily American Online (subscription),

Pharmacist accused of stealing drugs in Blackpool  -  Jul 4, 2008
Zayna Polakovs, 54, of Orkney Road, Blackpool, is charged with stealing nitrazepam, diazepam and temazepam from Whitworths Chemist, Blackpool. Blackpool Gazette,

FDA Safety Changes: Atripla, Halcion, Restoril  -  Jul 2, 2008
Describe the risks associated with the use of sedative-hypnotic agents such as triazolam and temazepam. Disclosure: Yael Waknine has disclosed no relevant Medscape (subscription)

‘My moment of madness’  -  Jun 25, 2008
He was found to have temazepam and cocaine in his system. Representing himself, he told the court he had had an argument with his girlfriend, describing his Whitehaven News,

Housebound mother took drugs with friends  -  Jun 8, 2008
When police executed a search warrant at the home of Susan Hannon, 43, they seized quantities of Amphetamines, cannabis and Temazepam. Northern Echo,

No rest for the busy  -  Jun 21, 2008
In the 18th Century insomniacs took opium, and later, in the 19th, potassium bromide, while they now guzzle zopiclone, valium and temazepam - doctors write BBC News,

Prescription Drugs: Rock's New Coke and Heroin?  -  Jun 28, 2008
...and Dark Knight star Heath Ledger overdosed in January from a deadly cocktail of oxycodone, hydrocodone, diazepam, temazepam, alprazolam and doxylamine. Wired Blogs

Drug addict admits new charges  -  Jun 17, 2008
The tablets were later found to be class A diamorphine and class C temazepam. During questioning, Gilligan, 26, told police he needed to pick up a methadone Northern Echo,

President Bush Inducted Into Druggie Hall Of Fame  -  Jun 12, 2008
...taking a break from cleaning his railroad, said: 'It ain't our fault George is so dumb, he's always been dumb, don't blame it on the temazepam, The Spoof (satire),

The day I was told I had lung cancer, by the brother of Radio 4's ...  -  Jun 16, 2008
That prescription might help - it was for temazepam. And will there be much pain? I don't think I'm keen on pain. It has to be said, I'm scared. Daily Mail,

Rescuing lost pup could cost man his liberty  -  02 Jun 2008
He was off work with depression and stress and had been prescribed temazepam to help him sleep and referred to a counsellor. The full article contains 257 Mansfield Chad,

Anesthesia and memory loss  -  02 Jun 2008
She takes prescription sleeping pills, alternating between Lunesta, Ambien CR and temazepam. They have not helped her sleep through the night. Seattle Times,

Bungling nurse given caution over sleeping pill overdose  -  May 30, 2008
Lucille Nwokocha, 65 of Wandsworth, gave the two elderly men double their required doses of Temazepam while on duty on the Jones Ward at the Royal Chelsea Epsom Guardian,

Young father died after cocktail of drink and drugs  -  May 29, 2008
An inquest at Halifax heard that Mr Jones, who has a young daughter, was also found to have a fatal mix of heroin, cocaine and Temazepam in his bloodstream. Hebdenbridge Today,

Commission rules against Gilbert  -  May 26, 2008
Eccles said Gilbert took valium, which breaks down into nordiazepam, oxazepam and temazepam. Gilbert also tested positive for amphetamine, nordiazepam, Tahoe Daily Tribune,

Commission rules against Gilbert  -  May 24, 2008
Eccles said Gilbert took Valium, which breaks down into nordiazepam, oxazepam and temazepam. Gilbert also tested positive for amphetamine, nordiazepam, Nevada Appeal,

Coming soon: the old geezer show  -  May 14, 2008
...in a field when half of Hollywood's young actors are busy mainlining Temazepam and Red Bull while stuffing their anorexic stomachs with kitchen roll. Times Online,

Drugs lost  -  May 14, 2008
The bag contained quantities of flupentixol, Temazepam, Diazepam and other medication. The tablets may be dangerous if taken without prescription and anyone ic Wales,

Pharmacist accused of forgery  -  May 16, 2008
Higher payments were made to Cristals Chemists for numerous prescriptions involving various medicines including tranquilisers Temazepam and Diazepam. Hertfordshire Mercury,

Dunn Police Make Drug Trafficking Bust  -  May 19, 2008
Officers found possession of 52.6 grams of oxycodone, 39.96 grams of Endocet, 10.4 grams of Temazepam, and 2.6 grams of hydrocodone. Dunn Daily Record,

Area woman caught with opiates  -  May 20, 2008
The women were caught last week in a convenience store parking lot with 52.6 grams of oxycodone, 39.96 grams of Endocet, 10.4 grams of Temazepam, Myrtle Beach Sun News,

OAP JAILED OVER 'LONELY HEARTS' RAPE  -  May 19, 2008
The court heard that the victim had been given enough of the sedative temazepam to debilitate her. Mr Hart said: "She was not taking a similar drug herself; Evening Post,

Nurse fell asleep on first night of work  -  May 19, 2008
Dodgson is even said to have made a patient suck a dissolving Temazepam from her finger. Care assistant Susan Bowman, who was working under Dodgson on that Bolton News,

Nurse axed for record keeping error  -  May 13, 2008
The independent panel was told he administered temazepam to the wrong patient and then recorded the dose in the incorrect record book. Hospital Healthcare Europe,

Teenager died after cocktail of drugs  -  May 12, 2008
A post mortem on 14-year-old Dane Edgar revealed he had traces of diazepam, temazepam, ecstasy, Piriton, and opiate substitute methadone in his blood. New Post Leader,

Patients’ details get lost in hospital thefts  -  May 9, 2008
...identity tags, ward keys and identity passes as well as thousands of pounds worth of drugs, such as methadone, morphine and temazepam. Gulf Times,

Use Caution When Stopping Meds  -  May 31, 2008
Sleeping pills: Ambien (zolpidem), Sonata, Lunesta and Restoril (temazepam) and Klonopin (clonazepam). Most sleepers are physically addictive, Best of Times,

Man on 7 drug deal charges  -  May 7, 2008
Substances allegedly found at his house in Banff Road, Greenock, on Friday were cocaine, cannabis resin, amphetamines, ecstasy, lysergide, temazepam and Greenock Telegraph,

Twisted Killer Visited His Pal's Girl Friend While On Release From ...  -  May 29, 2008
When out on a work placement, he was found smuggling 200 Temazepam into the jail and was sent back to Saughton. Some prison staff thought McGinlay was Glasgow Daily Record,

Mad Or Bad?  -  May 29, 2008
Some psychiatrists said he was sane but suffered a personality disorder, made worse by the consumption of booze and Temazepam. Others said he suffered from Glasgow Daily Record,

Experts cite lack of regulations  -  May 24, 2008
Benzodiazepines particularly alprazolam, clonazepam, temazepam and nimetazepam, he informed, adding that semi-synthetic and fully synthetic opiates like The News - International,

Pharmacist struck off for forgery  -  May 19, 2008
...relating to numerous prescriptions involving various medicines such as painkillers Temazepam - a Class C controlled drug - and Diazepam. Hertfordshire Mercury,

Motorbike death pair took drugs – inquest  -  May 15, 2008
...while his girlfriend, Ms Arthur, of South William Street, Workington, had taken amphetamine, cannabis, temazepam and paracetamol in her system. NW Evening Mail,

Koncept Analytics Report on Undiagnosed Sleep Disorder Market  -  May 6, 2008
Major products are Ambien, Ambien CR, Lunesta, Temazepam, and Zolpidem. Respironics and ResMed are the leading competitors in the continuous positive airway PR-Inside.com (Pressemitteilung),

America’s Chemically Modified 21st Century Soldiers  -  May 4, 2008
For side-effects like insomnia, the Air Force issues “no-go�? pills like temazepam alongside its “go�? pills. Psychosis, though, is a wee bit trickier. RINF.COM,

Brand Names/Synonyms:
Temazepam is also known by the following brand names and/or synonymsApo-Temazepam; Cerepax; Crisonar; ER 115; Euhypnos; Euipnos; Gelthix; Hydroxydiazepam; K-3917; Levanxene; Levanxol; Levanzene; Mabertin; Methyloxazepam; N-Methyloxazepam; Normison; Novo-Temazepam; Oxydiazepam; Perdorm; Planum; Remestan; Restoril; Signopam; Temaz; Temazepam; WY 2917; Wy-3917

Drug Category:
Temazepam is categorized under the following by the FDA: Anti-anxiety Agents; Adjuvants, Anesthesia; Benzodiazepines; GABA Modulators; ATC:N05CD07

Dosage Forms:
CAPSULE (7.5 mg, 15 mg, and 30 mg)

Absorption:
Well absorbed, minimal first-pass metabolism.

Interactions:
Interactions for Temazepam:

The pharmacokinetic profile of temazepam does not appear to be altered by orally administered cimetidine dosed according to labeling.

Chemical IUPAC Name:
10-chloro-4-hydroxy-6-methyl-2-phenyl-3,6-diazabicyclo[5.4.0]undeca-2,8,10,12-tetraen-5-one

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