Temazepam

This page contains recent news articles, when available, and an overview of Temazepam but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Temazepam (when available)

Pharmacology and use:
Temazepam is a benzodiazepine used as a hypnotic agent in the management of insomnia. Temazepam produces CNS depression at limbic, thalamic, and hypothalamic levels of the CNS. Temazepam increases the affinity of the neurotransmitter gamma-aminobutyric acid (GABA) for GABA receptors by binding to benzodiazepine receptors. Results are sedation, hypnosis, skeletal muscle relaxation, anticonvulsant activity, and anxiolytic action. For the short-term treatment of insomnia (generally 7-10 days).

Mechanism Of Action:
Benzodiazepines bind nonspecifically to benzodiazepine receptors, which affects affects muscle relaxation, anticonvulsant activity, motor coordination, and memory. As benzodiazepine receptors are thought to be coupled to gamma-aminobutyric acid-A (GABA_A) receptors, this enhances the effects GABA by increasing GABA affinity for the GABA receptor. Binding of the inhibitory neurotransmitter GABA to the site opens the chloride channel, resulting in a hyperpolarized cell membrane that prevents further excitation of the cell.

News Articles on Temazepam

Dimond: The Addict, the Enabler and Us  -  ‎Aug 29, 2009‎
But there they were: bottles of Valium, Tamsulosin, Lorazepam, Temazepam, Clonazepam, Trazodone and Tizanidine. Drugs used as hypnotic sedatives, INDenverTimes.com

One-Time Seizes a Lil Twenty Twen Twen from mj's Crib  -  ‎Aug 28, 2009‎
Two bags of marijuana, a bottle of temazepam (used to treat sleeplessness), empty bottles of the sedatives lorazepam and diazepam were discovered during the Bossip

Report: Michael Jackson Death Ruled Homicide  -  ‎Aug 24, 2009‎
Other drugs confiscated in the search of Jackson's Holmby Hills mansion included Valium, Tamsulosin, Lorazepam, Temazepam, Clonazepam, Trazodone, Rap-Up.com

Married GP 'refused to give me anti-depressants unless I agreed to ...  -  ‎Aug 25, 2009‎
She claimed that in order to maintain her prescriptions for Temazepam and Valium she would have to have sex with him almost every time she went to the Daily Mail

Cocaine a Contributing Cause of Billy Mays' Death  -  ‎Aug 10, 2009‎
...oxycodone (painkiller), alprazolam (Xanax), nordiazepam (Valium), benzoylecgonine (byproduct of cocaine) and temazepam (anti-anxiety). New York Post

Cocaine contributed to death at 50 of hyperactive OxiClean ...  -  ‎Aug 7, 2009‎
The other tablets are benzodiazepines, both to aid sleep (temazepam) and relieve anxiety (Xanax and Valium). What is interesting to note is that he had Telegraph.co.uk

Mum's 2400 painkillers from Pakistan  -  ‎Aug 22, 2009‎
Magistrates were told that Angela Vanes, 42, ordered the Temazepam tablets to relieve her pain and help her sleep while waiting for a back operation after Hartlepool Today

Driver who took sleeping pills smashed into cars  -  ‎Aug 22, 2009‎
But a blood test showed trace of diazepam and temazepam. Prior pleaded guilty to two offences of leaving the scene of an accident and one of driving while Sunderland Echo

In a world obsessed with staying young, a refreshingly honest ...  -  ‎Aug 14, 2009‎
But recently, I woke at 9am - that's what happens when you take a quarter of a Temazepam (see 'Free Drugs' below) and a mug of Horlicks at 4.30am because Daily Mail

Heroin in Michael Jackson's home?  -  ‎Aug 28, 2009‎
According to the newest search warrant, there were other drugs found, including two bags of marijuana, the generic form of Valium, a bottle of temazepam TheCelebrityCafe.com

£500 cocaine suspect denies being a dealer  -  ‎Aug 7, 2009‎
They also found some Temazepam tablets, £3690 cash and a book containing names and figures, a Durham Crown Court jury was told. But Ian Swift, an employee Northern Echo

BHA set to relax totting-up rules  -  ‎Aug 26, 2009‎
Also on the BHA's agenda today is the case of Wrighty Almighty, who tested positive for Temazepam at Brighton on 22 May, when he was the 2-1 favourite. guardian.co.uk

What I learned at doggy boot camp  -  ‎Aug 13, 2009‎
And here, with my darling temazepam, I have a heavenly sleep. Which is lucky, because the dogs are first up again in the morning, at 6.05am. Horrid. guardian.co.uk

A pizza, garlic bread and Tamiflu, anyone?  -  ‎Aug 6, 2009‎
...“A special offer on temazepam? No thanks. When can you deliver my order by? Can you make it for eight?�? This phone order business is also putting the health News & Star

US Judge Denies Covidien Effort To Block Generic Sleep Drug  -  ‎Aug 5, 2009‎
1, 2006, seeking approval to make and sell the drug, which is known generically as temazepam. A 30-month stay on FDA approval of that application is set to Wall Street Journal

What happened to the Trainspotting generation?  -  ‎Aug 14, 2009‎
..."Culturally, a lot of people prefer depressing drugs like opiates – heroin, Temazepam. The problem is if you take these drugs in combination and add alcohol guardian.co.uk

Scottish drug deaths reach record level  -  ‎Aug 12, 2009‎
There was a "marked fall" in the number of deaths involving temazepam, once one of Scotland's most abused drugs by younger people, while ecstasy was guardian.co.uk

Ledger's 'Imaginarium' Trailer Debuts  -  ‎Aug 11, 2009‎
The coroner reported that Ledger died of an accidental overdose "by the combined effects of oxycodone, hydrocodone, diazepam, temazepam, alprazolam, Popeater

Biotech/Pharma Docket  -  ‎Aug 11, 2009‎
5211954, is directed to a low-dose temazepam composition. The original suit, filed by Covidien's predecessor Tyco Healthcare Group LP against URL Patent Docs

hooked at birth  -  ‎Aug 16, 2009‎
...mums-to-be are taking heroin and methadone, while 29 per cent use cannabis and 11 per cent knock back sedatives such as Diazepam and Temazepam. The Sun

Former college chief pays tribute to cliff plunge man  -  ‎Aug 14, 2009‎
It read: “Kevin was depressed and took an overdose of Temazepam in May and spent two weeks in hospital. “He was severely depressed and kept saying there was Whitby Today

Michael Jackson: Uri Geller says he was 'killing himself slowly ...  -  ‎Aug 25, 2009‎
Following Jackson's death other drugs reportedly confiscated in the search at the star's residence included tamsulosin, temazepam, clonazepam, trazodone and Telegraph.co.uk

Scottish drug deaths soar due to legacy of addiction  -  ‎Aug 13, 2009‎
The only positive notes in the report were a fall in deaths of people aged under 25 and a decrease in deaths due to temazepam. Heroin and/or morphine were OnMedica

Paramedic denies sex in public accusation  -  ‎Aug 12, 2009‎
The panel also went into closed session to discuss Mr Brammer's health and psychological issues after being told he was using the sedative temazepam at the Yorkshire Post

College chief died in plunge at cliffs  -  ‎Aug 11, 2009‎
The statement said: "Kevin was depressed and took an overdose of Temazepam in May and spent two weeks in hospital. He was severely depressed and kept saying Yorkshire Post

Reclaim the right to your grief  -  ‎Aug 5, 2009‎
Not sleeping - how about some Temazepam? No energy? Try some uppers. Feeling depressed? Here's a script for Zoloft. (In Mum's case, I downed a bottle of Daily Telegraph

08-25-09 EUR ALL ON ONE PAGE  -  ‎Aug 25, 2009‎
Other drugs that were confiscated in the search included valium, tamsulosin, lorazepam, temazepam, clonazepam, trazodone and tizanidine. Eurweb.com

Drug Deaths On The Rise  -  ‎Aug 26, 2009‎
Of the 13, seven were found to have taken diazepam, four methadone, two cocaine and one temazepam. None were found with traces of amphetamines or ecstasy. Cumnock Chronicle

Maconha é encontrada na casa de Michael Jackson  -  ‎Aug 28, 2009‎
Dois sacos de maconha, embalagem do medicamento temazepam - usado para tratar insônia - e embalagens dos sedativos lorzaepam e diazepam foram descobertas O Globo

警方�?�查文件解�? �?�克逊家中�?�现大麻  -  ‎Aug 28, 2009‎
...具体包括：两包大麻，一瓶替马西泮(temazepam，用于治疗失眠)，镇�?�剂lorzaepam和diazepam的空瓶，还有4个�?知�?�装过什么的空瓶。 �?�查文件中说，警方担心，�?�克逊去世黑龙江新闻网

米高冥壽新蠟�?開幕  -  ‎Aug 28, 2009‎
...藥瓶分別盛載�?�，鎮�?�劑Lorzaepam 和Diazepam�?Temazepam（治療失眠）�?異丙酚等，�?�在米高�?�房發�?�海洛英。首席助�?�驗�?官Ed Winte指米高驗�?�?果未公布�?，他�?能新報

Maconha é encontrada na casa de Michael, diz site  -  ‎Aug 28, 2009‎
Os sedativos lorzaepam, diazepam e temazepam, este último usado no tratamento de insônia, foram descobertos quatro dias depois da morte do rei do pop, Diário do Grande ABC

La mort de Michael Jackson attribuée au Propofol  -  ‎Aug 24, 2009‎
Craignant une addiction, il avait diminué les doses à 25 mg par jour, combinées à d'autres sédatifs : Valium, Tamsulosin, Lorazepam, Temazepam, Clonazepam, France Info

Tìm thấy cần sa trong nhà Michael Jackson  -  ‎Aug 27, 2009‎
Cảnh sát thu được hai túi cần sa, một l�? thuốc chữa chứng mất ngủ temazepam, một số l�? thuốc giảm đau lorzaepam và diazepam đã dùng hết tại nhà của Báo Đất Việt

Medic acuzat ca a facut sex cu o pacienta in cabinet, in timp ce ...  -  ‎Aug 25, 2009‎
In timp, Rusling ia prescris o serie de medicamente, printre care Temazepam si Valium, de care femeia a devenit dependenta. El a amenintat-o ca-i va retrage Ziua

Weed gevonden bij huis Michael Jackson  -  ‎Aug 28, 2009‎
Politieagenten hebben kort na de dood van de King of pop twee zakjes met weed en lege potjes temazepam, lorzaepma en diazepam gevonden. Bruno.nl

Lekarz wykorzystywał pacjentkę, a mąż siedział za ścianą  -  ‎Aug 25, 2009‎
Cała sprawa zaczęła się w 2004 roku, kiedy kobieta przyszła do lekarza po receptę na psychotropowy lek Temazepam, od którego była uzależniona. Wirtualna Polska

警方�?�查文件解�? 迈克尔�?�克逊家中�?�现大麻  -  ‎Aug 27, 2009‎
...具体包括：2包大麻，一瓶替马西泮（temazepam，用于治疗失眠），镇�?�剂lorzaepam 和diazepam的空瓶，还有4个�?知�?�装过什么的空瓶。 �?�查文件中说，警方担心，�?�克逊北青网

Policia achou maconha e varios vidros de remédios na casa de Jackson  -  ‎Aug 28, 2009‎
Os medicamentos eram temazepam (usado para insônia), lorzaepam e diazepam (sedativos). Havia ainda vidros vazios e nao identificados que nao permitiam saber Blue Bus

Marihuana gevonden in huis van Jackson  -  ‎Aug 28, 2009‎
Agenten troffen twee zakjes met marihuana aan en verpakkingen van de slaap- en kalmeringsmiddelen temazepam, lorzaepam en diazepam. Stentor

Marijuana trouvée à la maison de Michael Jackson  -  ‎Aug 28, 2009‎
En plus de la marijuana, une bouteille de temazepam, utilisé pour contrer les problèmes d'insomnie, et plusieurs flacons vides des sédatifs lorzaepam et Canoë

Consumía cocaína Billy Mays antes de morir  -  ‎Aug 7, 2009‎
...oxicodona (analgésico), alprazolam (Xanax), nordiazepam (Valium), benzoilecgonina (subproducto de la cocaína) y temazepam (contra la ansiedad). Akro Noticias

Polícia encontrou maconha no quarto de Michael Jackson  -  ‎Aug 28, 2009‎
De acordo com mandados de busca divulgados esta semana, também foram achados na mansão dele em Beverly Hills um frasco de temazepam (usado para o tratamento Abril

Fant marihuana i Michael Jacksons hjem  -  ‎Aug 28, 2009‎
Totalt skal politiet ha funnet to poser marihuana, en boks temazepam, som brukes mot søvnløshet, tomme bokser lorazepam som brukes mot angst, Dagbladet.no

Michael Jackson: Wichtige Zeugen wurden noch nicht vernommen  -  ‎Aug 28, 2009‎
Bei der Durchsuchung fand man zwei Tüten mit der Droge, eine Flasche des Schlafmittels Temazepam, leere Schachteln der Beruhigungsmittel Lorazepam und Gala.de

Quentin Tarantino tem melhor estreia de sua carreira  -  ‎Aug 24, 2009‎
Na mansão onde ele morreu, a polícia encontrou Propofol, Valium, Tamsulosin, Lorazepam, Temazepam, Clonazepam, Trazodone e Tizanidine. (Planet Pop) Abril

Michael Jackson morto per una dose letale di Propofol  -  ‎Aug 24, 2009‎
Tra i farmaci sequestrati dalla polizia ci sono: il valium, il tamsulosin, il lorazepam, il temazepam, il clonazepam, il trazodone e il tizanidine. In dies

�?окаутирующие капли  -  ‎Aug 13, 2009‎
GBL), а также Benzodiazepine, Flunitrazepam и Temazepam (�?пециально перечи�?л�?ем �?ти названи�?: в пре�?тупном мире они и без того изве�?тны, а вот родител�?м Русская Германия

Oproep: gevaarlijke medicijnen verloren  -  ‎Aug 9, 2009‎
De medicijnen kunnen zeer gevaarlijk zijn. Het gaat om Fluanxol, Paroxetine, Temazepam, Abilify, Akeniton, Amitriptyline, Buspiron en Clozapine. RTV Utrecht

Brand Names/Synonyms:
Temazepam is also known by the following brand names and/or synonymsApo-Temazepam; Cerepax; Crisonar; ER 115; Euhypnos; Euipnos; Gelthix; Hydroxydiazepam; K-3917; Levanxene; Levanxol; Levanzene; Mabertin; Methyloxazepam; N-Methyloxazepam; Normison; Novo-Temazepam; Oxydiazepam; Perdorm; Planum; Remestan; Restoril; Signopam; Temaz; Temazepam; WY 2917; Wy-3917

Drug Category:
Temazepam is categorized under the following by the FDA: Anti-anxiety Agents; Adjuvants, Anesthesia; Benzodiazepines; GABA Modulators; ATC:N05CD07

Dosage Forms:
CAPSULE (7.5 mg, 15 mg, and 30 mg)

Absorption:
Well absorbed, minimal first-pass metabolism.

Interactions:
Interactions for Temazepam:

The pharmacokinetic profile of temazepam does not appear to be altered by orally administered cimetidine dosed according to labeling.

Chemical IUPAC Name:
10-chloro-4-hydroxy-6-methyl-2-phenyl-3,6-diazabicyclo[5.4.0]undeca-2,8,10,12-tetraen-5-one

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