Tamsulosin

This page contains recent news articles, when available, and an overview of Tamsulosin but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Tamsulosin (when available)

Pharmacology and use:
Tamsulosin, an alpha-adrenoceptor blocker with enhanced specificity for the alpha-adrenoceptors of the prostate, is commonly used to treat benign prostatic hyperplasia (BPH). Used in the treatment of signs and symptoms of benign prostatic hyperplasia.

Mechanism Of Action:
Tamsulosin is a selective antagonist at alpha-1A and alpha-1B-adrenoceptors in the prostate, prostatic capsule, prostatic urethra, and bladder neck. At least three discrete alpha1-adrenoceptor subtypes have been identified: alpha-1A, alpha-1B and alpha-1D; their distribution differs between human organs and tissue. Approximately 70% of the alpha1-receptors in human prostate are of the alpha-1A subtype. Blockage of these receptors causes relaxation of smooth muscles in the bladder neck and prostate.

News Articles on Tamsulosin

Dimond: The Addict, the Enabler and Us  -  ‎Aug 29, 2009‎
But there they were: bottles of Valium, Tamsulosin, Lorazepam, Temazepam, Clonazepam, Trazodone and Tizanidine. Drugs used as hypnotic sedatives, INDenverTimes.com

Jacko: It WAS homicide  -  ‎Aug 24, 2009‎
Other drugs confiscated in the raid included valium, tamsulosin, lorazepam, temazepam, clonazepam, trazodone and tizanidine. Tamsulosin is used to treat an The Sun

Obama & God LLP  -  ‎Aug 21, 2009‎
We don't even know what "wee weed up" means, although the president's comment does lead us to wonder if ObamaCare would cover Tamsulosin prescriptions. Wall Street Journal

Astellas results healthy, links up with AstraZeneca  -  ‎Aug 4, 2009‎
Turnover was driven by the immunosuppressant Prograf (tacrolimus), down 0.4% to 52.00 billion yen, and Harnal (tamsulosin) for benign prostatic hyperplasia, Pharma Times

Michael Jackson: Uri Geller says he was 'killing himself slowly ...  -  ‎Aug 25, 2009‎
Following Jackson's death other drugs reportedly confiscated in the search at the star's residence included tamsulosin, temazepam, clonazepam, trazodone and Telegraph.co.uk

Charles Bonnet syndrome: visual loss and hallucinations  -  ‎Aug 3, 2009‎
He was also taking tamsulosin and dutasteride for benign prostatic hypertrophy and allopurinol for gout. None of his medications had been changed before the CMAJ

08-25-09 EUR ALL ON ONE PAGE  -  ‎Aug 25, 2009‎
Other drugs that were confiscated in the search included valium, tamsulosin, lorazepam, temazepam, clonazepam, trazodone and tizanidine. Eurweb.com

La mort de Michael Jackson attribuée au Propofol  -  ‎Aug 24, 2009‎
Craignant une addiction, il avait diminué les doses à 25 mg par jour, combinées à d'autres sédatifs : Valium, Tamsulosin, Lorazepam, Temazepam, Clonazepam, France Info

Wenn Äskulap dichtet Medizin und Wahnsinn (92)  -  ‎Aug 15, 2009‎
Tamsulosin und Tandaradei, wer will so etwas lesen? Nach dem Samenerguss kommt der Autor umstandslos zur Seifenbürstenmassage im Friedrichsbad in sueddeutsche.de

�?列腺肥大的藥物治療  -  ‎Aug 9, 2009‎
...目�?臨床上使用於BPH的α-阻斷劑包括prazosine�?terazosin�?alfuzosin�?�tamsulosin等，這些藥物�?�具有�?�?�的�?�體特異性�?�藥效�?久性，此外在病患�?用�?�?�性上有些許 uho優活健康網

Quentin Tarantino tem melhor estreia de sua carreira  -  ‎Aug 24, 2009‎
Na mansão onde ele morreu, a polícia encontrou Propofol, Valium, Tamsulosin, Lorazepam, Temazepam, Clonazepam, Trazodone e Tizanidine. (Planet Pop) Abril

Conférence de 13 heures du Mardi, 25 Août 2009  -  ‎Aug 25, 2009‎
Craignant une addiction, il avait diminué les doses à 25 mg par jour, combinées à d'autres sédatifs : Valium, Tamsulosin, Lorazepam, Temazepam, Clonazepam, MediaPart

尸检结果：�?�克逊死于他�?�(组图)  -  ‎Aug 25, 2009‎
...�?�洛新胶囊（Tamsulosin）：治疗�?列腺增生。氯�?安定（Clonazepam）：长效肌肉放�?�剂。氯哌三唑酮（Trazodone）：抗抑�?�?�。替扎尼定（Tizanidine）：治疗肌肉和讯网

Michael Jackson morto per una dose letale di Propofol  -  ‎Aug 24, 2009‎
Tra i farmaci sequestrati dalla polizia ci sono: il valium, il tamsulosin, il lorazepam, il temazepam, il clonazepam, il trazodone e il tizanidine. In dies

Niveles letales" de anestésico causaron la muerte de Michael Jackson  -  ‎Aug 24, 2009‎
La policía también encontró Valium, Tamsulosin, Lorazepam, Temazepam, Clonazepam, Trazodone y Tizanidine, junto con el Propofol. Varios de esos medicamentos SDP Noticias

Tamsulosin use linked with postop cataract surgery complications  -  ‎Jul 10, 2009‎
The use of tamsulosin to treat prostate enlargement and urinary symptoms was linked with an elevated risk of complications after cataract surgery, OSN SuperSite

The Risk of Fracture With Taking Alpha Blockers for Treating ...  -  ‎Jul 8, 2009‎
Doxazosin and tamsulosin showed the increased risk of fractures, whereas terazosin did not. After stratification using the defined daily doses, a protective UroToday

Prostate Condition Symptoms Linked to Ejaculation Problems Review ...  -  ‎Jul 7, 2009‎
...were also associated with ejaculatory dysfunction, such as transurethral resection of the prostate or use of the drugs tamsulosin and silodosin. Modern Medicine

ASTELLAS ANNOUNCES SUBMISSION OF PEDIATRIC DATA FOR FLOMAX ...  -  ‎Jul 1, 2009‎
Tamsulosin hydrochloride was invented and developed by Astellas for the treatment of the signs and symptoms of benign prostatic hyperplasia (BPH) and has PipelineReview.com (press release)

Serenoa Repens for Benign Prostatic Hyperplasia - Abstract  -  ‎Jun 18, 2009‎
Serenoa repens was not superior to finasteride (MD -0.05 nocturnal visits, 95% CI -0.49 to 0.39, P > 0.05; 1 trial), or to tamsulosin (per cent improvement) UroToday

Ejaculatory Dysfunction in Men with Lower Urinary Tract Symptoms ...  -  ‎Jun 28, 2009‎
Men with previous BPH-related surgery and men treated with a 5alpha-reductase inhibitor plus an alpha(1)-blocker or tamsulosin alone showed the highest UroToday

'플로맥스' 美서 소아임�?�?��?�터 제출  -  ‎Jul 1, 2009‎
...배뇨장애 개선제 '플로맥스'(FLOMAX, tamsulosin)�?� 소아임�?�?��?�터가 미국 FDA�? 제출�??다. �?�본 아스텔�?�스제약�?� 최근 제휴회사�?� 베�?거�?�겔하임�?� 미국 메디파나뉴스

Kidney stones can cause intense pain, nausea  -  ‎Apr 19, 2009‎
Tamsulosin (Flomax), a medication that relaxes muscles in the ureter, can help, too. Because kidney stones are among the most painful conditions you're Detroit Free Press

FDA Rules on Drug Ads Sow Confusion as Applied to Web  -  ‎Apr 17, 2009‎
...which results in ads like, “Flomax® (tamsulosin HCl) www.4FLOMAX.com Capsules, 0.4 mg - Official Site for Important Product Information. New York Times

Evaluation of Selective and Non-Selective Alpha-Andrenergic ...  -  ‎Apr 7, 2009‎
Patients in Group 3 were given the selective α 1a -adrenergic receptor blocker Tamsulosin (0.4 mg) once daily in addition to the standard treatment. UroToday International Journal

Postlithotripsy Agents Improve Stone Outcomes  -  ‎Apr 2, 2009‎
MET agents used in the trials were tamsulosin, nifedipine, and Phyllanthus niruri extract. Trevor D. Schuler, MD, and colleagues at St. Michael's Hospital Renal and Urology News

Finasteride's prostate benefits confirmed  -  ‎Apr 14, 2009‎
Of the 23320 men, 1754 men (7.5%) had used finasteride and 3848 (16.5%) had used an alpha blocker (either tamsulosin or alfuzosin). Cortlandt Forum

A Broader Role for 5ARIs in Prostate Disease? Existing Evidence ...  -  ‎Mar 29, 2009‎
...while the ongoing CombAT trial (dutasteride/tamsulosin) has for the first time shown benefit in improving symptoms for combination therapy over UroToday

A Broader Role For 5ARIs In Prostate Disease? Existing Evidence ...  -  ‎Apr 14, 2009‎
Dutasteride in combination with tamsulosin (CombAT trial) is underway and interim analysis suggests similar superiority to either agent alone. Medical News Today (press release)

브랜드 항우울-제네릭 항염제 �?��?  -  ‎Apr 19, 2009‎
...다�?�으로 ‘웰부트린'�?� 21%, ‘루네스타'(Lunesta, eszopiclone)가 20.3%, ‘카타푸레스'가 19.3%, ‘플로맥스'(Flomax, tamsulosin)가 19.1%, ‘리�?�'�?� 19%�?� 순으로 디지틀보사

�?年病用�?�需求�?�?断增长�?列腺用�?�“增生�?  -  ‎Apr 2, 2009‎
...�?�洛新(tamsulosin)�?�洛新由日本山之内公�?�(Yamanouchi)开�?�，1993年以商�?�??“Harnal�?首次上市，在欧洲商�?�??为“Flomax�?。该�?�于1996年投入我国市场，国内商�?�??为“哈搜狐

AOK schlägt weiter zu  -  ‎Apr 17, 2009‎
Die Wirkstoffe Alendronsäure, Tamsulosin und Molsidomin teilen sie sich mit anderen Herstellern. Weitere Rabattverträge über einzelne Wirkstoffe und apotheke-adhoc

Reduce Ranbaxy Laboratories, target of Rs 155: IIFL  -  18 Mar 2009
..."We also expect the management to successfully shift the location of filing for the valacyclovir and tamsulosin exclusivities that are due to come through Moneycontrol.com

Effect Of Tamsulosin On Systemic Blood Pressure And Nonneurogenic ...  -  ‎Mar 16, 2009‎
UroToday.com - A study by Brian VanderBrink et al. evaluated the effect of tamsulosin on systemic blood pressure in children and non-neuropathic Medical News Today (press release)

Adding Tamsulosin Does Not Aid Ureteral Stone Passage  -  ‎Feb 26, 2009‎
Adding tamsulosin to ibuprofen and oxycodone does not improve outcomes in patients treated for ureteral stones in the emergency department (ED), Renal and Urology News

Research and Markets: Gain Insight into the Flomax Case Study ...  -  ‎Mar 9, 2009‎
Prostatic Hyperplasia) indicated product, Flomax/Tamsulosin, to differentiate the product and to boost disease awareness to expand the product market. MarketWatch (press release)

Effect of Discontinuation of 5alpha-Reductase Inhibitors on ...  -  ‎Mar 2, 2009‎
The patients were randomized into 2 groups: group 1 received finasteride 5 mg plus alfuzocin 10 mg or tamsulosin 0.2 mg daily, and group 2 received UroToday

Health column: Reader's craving for ice leads to cancer diagnosis  -  ‎Feb 24, 2009‎
A. Flomax (tamsulosin) relieves prostate problems by helping smooth muscle relax and improving urine flow. In 2005, ophthalmologists reported that patients Pottstown Mercury

�?�?�?藥�?�多胡言亂語籲藥事照護�?入長照體系  -  ‎Mar 12, 2009‎
...症�?心臟病，一天�?�?�必須�?�上�??一種藥�?，北縣執業藥師張玉錦指出，因為�?先生�?�?�進很多藥�?，憂鬱症的錠劑Venlafaxine-xR�?��?護腺肥大的藥�?Tamsulosin�?容易�?� uho優活健康網

Two Drugs Better than One for LUTS  -  Jan 22, 2009
Combination therapy with tamsulosin and extended-release oxybutynin is superior to tamsulosin alone in treating men with lower urinary tract symptoms (LUTS) Renal and Urology News,

NPA Backs Tamsulosin Switch, UK  -  Jan 23, 2009
The NPA supports the proposed POM to P switch of tamsulosin, for the treatment of lower of benign prostatic hyperplasia (BPH) - which causes lower urinary Medical News Today (press release),

Prescription Meds Over-the-Counter  -  Jan 16, 2009
The drugs in question are trimethoprim, an antibiotic often used to treat women with urinary infection cystitis, and tamsulosin (Flomax), used to treat KCEN-TV,

What's the evidence for saw palmetto plant extracts?  -  Jan 21, 2009
Comparison of a phytotherapeutic agent (Permixon) with an a-blocker (tamsulosin) in the treatment of benign prostatic hyperplasia: a 1-year randomized guardian.co.uk,

Providing prescription drugs over the counter 'will not help patients'  -  Jan 13, 2009
64.5 per cent, said trimethoprim should not be available in pharmacies without prescription, and 79.7 per cent said the same about tamsulosin. Telegraph.co.uk,

What treatments work for chronic prostatitis?  -  Jan 21, 2009
...[4] But in a larger study, tamsulosin didn't help men who had severe symptoms for many years, and who had tried lots of different treatments. guardian.co.uk,

What's the evidence for alpha-blockers?  -  Jan 21, 2009
Wilt TJ, MacDonald R, Nelson D. Tamsulosin for treating lower urinary tract symptoms compatible with benign prostatic obstruction: a systematic review of guardian.co.uk,

Two Thirds Of Doctors Against Moving Antibiotic Trimethoprim To OTC  -  Jan 19, 2009
The survey also found that nearly 80% of doctors opposed the switching of the drug tamsulosin for benign prostatic hyperplasia (BPH), which is also Medical News Today (press release),

savvy senior  -  Jan 26, 2009
GERD drugs Prevacid (lansoprazole) and Aciphex (rabeprazole), and enlarged prostrate drug Flomax (tamsulosin). Many chains like Wal-Mart, Target, Seymour Herald,

Savvy Senior  -  Jan 24, 2009
GERD drugs Prevacid (lansoprazole) and Aciphex (rabeprazole), and enlarged prostrate drug Flomax (tamsulosin). Many chains like Wal-Mart, Target, Fergus Falls Daily Journal,

Incontinence, common among elderly, can be controlled  -  Jan 15, 2009
These include terazosin (Hytrin), doxazosin (Cardura), alfuzosin (Uroxatral), and tamsulosin (Flomax). Some of the older agents in this group can decrease Great Falls Tribune,

Ärzte kritisieren OTC-Freigabe  -  Jan 16, 2009
Berlin - Ärzte in Großbritannien stehen den Plänen der britischen Arzneimittelbehörde MHRA, das Antibiotikum Trimethoprim und den alpha-1-Blocker Tamsulosin apotheke-adhoc,

한국아스텔�?�스제약 ‘EMU 심�?�지엄’  -  Jan 28, 2009
...환�?들�?게 �?� 치료로 얼마나 좋아졌는가를 질문했�?� 때 플�?�시보 군�?서는 61.7%, tolterodine only 군 65.6%, tamsulosin only 군 77.5%, 콤비네�?�션 군�?서는 80% 디지틀보사,

「石�?在惱人談尿路�?石  -  Jan 14, 2009
...研究也發�?�，傳統�?護腺用藥的α-1a甲型阻斷劑（學�??Tamsulosin 中時電�?報,

GlaxoSmithKline Files Duodart Euro Marketing Authorisation  -  Dec 19, 2008
This MAA file is based on positive two year results results from the Combination of AvodartR and Tamsulosin (CombAT) study, and studies showing EasyBourse.com,

Firm applies for prostate treatment to be over the counter  -  Dec 2, 2008
Enlarged prostate treatment tamsulosin could be made available over the counter (OTC), following an application by Boehringer-Ingelheim to have Flomax Healthcare Republic (press release),

英 전립선비대약 OTC 전환 고려  -  Dec 3, 2008
...�?국�?서 전립선비대�? 치료제�?� ‘플로맥스’(Flomax, tamsulosin)�? 대한 OTC 전환�?� 고려�?�고 있다. �?국�?� �?�약품 규제당국�?� MHRA는 최근 �?��? 대한 �?�견�?� 듣기 디지틀보사,

Conservative Treatment Is the Answer  -  Nov 21, 2008
Medics considered this fact and suggested using conservative treatment – patients received a drug, which was an improved form of tamsulosin. Russia-InfoCenter,

Recordati SpA SUBMITS FILE FOR APPROVAL OF SILODOSIN TO THE EMEA  -  Nov 21, 2008
Furthermore, in theactive-controlled study conducted in Europe, silodosin 8mg once daily wasnot inferior to tamsulosin 0.4mg once daily, with an adjusted International Business Times,

21/11/08 11:58 Recordati SpA : RECORDATI DEPOSE UNE DEMANDE D ...  -  Nov 21, 2008
Furthermore, in the active-controlled study conducted in Europe, silodosin 8mg once daily was not inferior to tamsulosin 0.4mg once daily, with an adjusted TF1,

Ask the Eye Guy: Medicines can have impact on cataract surgery  -  Nov 9, 2008
The other group of medications are alpha adrenergic blockers such as Flomax (tamsulosin). This dilates blood vessels and also relaxes muscles tissue in the Annapolis Capital,

「氰�?「石�?難安從三�?�氰胺談尿路�?石治療  -  Nov 11, 2008
...若無明顯症狀，�?�多�?水加上�?�當�?�動�?��?律追蹤，待石頭自行排出；若石頭滾�?�至輸尿管，症狀�?��?嚴�?，�?�加上藥物治療（如甲型交感神經阻斷劑Tamsulosin 中時電�?報,

Floppy iris syndrome manageable with the right viscoadaptive OVD  -  Oct 8, 2008
The relaxing effect of tamsulosin on the pupil may cause damage in what might at first appear to be a standard cataract surgery. OSN SuperSite (subscription),

BPH Drugs May Differ in Effects on Fracture Risk  -  Oct 7, 2008
Examples of selective alpha-blockers include tamsulosin (Flomax) and alfuzosin (UroXatral). The authors pointed out that "a well-known adverse effect of MedPage Today,

「一箭雙雕�? �?護腺藥一藥兩用  -  Oct 7, 2008
...症狀，�?��?�增加�?石排出的機會；用於�?石的病患身上，通常以�?�擇�?血壓作用很�?的α-1a甲型阻斷劑（學�??Tamsulosin 中時電�?報,

هل يؤثر التوتر �?ي تضخم البروستاتا؟  -  Oct 4, 2008
...(Hytrin «دوكسازوسين» (كاردورا)(doxazosin (Cardura «تامسولاسين» (�?لوماكس) tamsulosin (Flomax)، «ال�?وزوسين» (يوراكساترول)(alfuzosin (Uroxatrol. الشرق الاوسط,

Brand Names/Synonyms:
Tamsulosin is also known by the following brand names and/or synonymsFlomax; Harnal; Omnic; Pradif; TAMSULOSIN; Tamsolusin; Tamsulosin; Tamsulosina [Inn-Spanish]; Tamsulosine [Inn-French]; Tamsulosinum [Inn-Latin]

Drug Category:
Tamsulosin is categorized under the following by the FDA: Antineoplastic Agents; ATC:G04CA02

Dosage Forms:
CAPSULE (SUSTAINED-RELEASE)

Absorption:
Absorption of tamsulosin HCI from capsules 0.4 mg is essentially complete (>90%) following oral administration under fasting conditions.

Interactions:
Interactions for Tamsulosin:

Drug-Drug Interactions: The pharmacokinetic and pharmacodynamic interactions between FLOMAX capsules and other alpha-adrenergic blocking agents have not been determined. However, interactions may be expected and FLOMAX capsules should NOT be used in combination with other alpha-adrenergic blocking agents.

The pharmacokinetic interaction between cimetidine and FLOMAX capsules was investigated. The results indicate significant changes in tamsulosin HCI clearance (26% decrease) and AUC (44% increase). Therefore, FLOMAX capsules should be used with caution in combination with cimetidine, particularly at doses higher than 0.4 mg.

Results from limited in vitro and in vivo drug-drug interaction studies between tamsulosin HCI and warfarin are inconclusive. Therefore, caution should be exercised with concomitant administration of warfarin and FLOMAX capsules.

Chemical IUPAC Name:
5-[2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulfonamide

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