Tagamet

This page contains recent news articles, when available, and an overview of Tagamet but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Tagamet
(when available)

Pharmacology and use:
Cimetidine is a histamine H2-receptor antagonist. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. It is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Cimetidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Cimetidine include an increase in gastric bacterial flora such as nitrate-reducing organisms. For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion

Mechanism Of Action:
Cimetidine binds to an H2-receptor located on the basolateral membrane of the gastric parietal cell, blocking histamine effects. This competitive inhibition results in reduced gastric acid secretion and a reduction in gastric volume and acidity.

News Articles on Cimetidine

Calcium curious: How much is enough?  -  ‎Aug 10, 2009‎
People taking medications that reduce stomach acid -- such as the proton-pump inhibitors (Prevacid, Prilosec) or the H2 blockers (Tagamet, Zantac) -- should Chicago Tribune

Medications to avoid when trying to get pregnant  -  ‎Aug 12, 2009‎
For men, the list of potential culprits includes the heartburn medication cimetidine (Tagamet), the rheumatoid arthritis drug (Azulfidine), Examiner.com

Teacher connects with students using humor  -  ‎Aug 27, 2009‎
..."Where's Tagamet? Ryan Taggarse," he called out to another. And just like that -- like hundreds of students before them -- David and Ryan had just been Ellicott City View

Federal study finds traces of drugs in Fanno Creek  -  ‎Aug 26, 2009‎
...in the nation's urban waterways, and a 2007 story in The Oregonian highlighted the presence of caffeine, Prozac and Tagamet in Portland-area rivers. OregonLive.com

Munch goes to Dormont Dogs  -  ‎Aug 26, 2009‎
Tagamet sold separately. Meanwhile LBOM, beefing up for a season as the starting nose tackle for the Carrick Raiders, did yeoman's work on the Pizza Dog Pittsburgh Post Gazette

Taking care of stomach ulcers  -  ‎Aug 25, 2009‎
...blocker (H-2 blocker) such as Zantac, Pepcid, Tagamet or Axid. An antacid may also be included to neutralize existing acids and give quick pain relief. Enid News & Eagle

7 Common Digestive Problems and How to End Them  -  ‎Aug 19, 2009‎
...such as the proton pump inhibitors Aciphex, Nexium, Prevacid, Prilosec, and Protonix and the H2 blockers Axid, Pepcid, Tagamet, and Zantac. Hartford Courant

Why Single-Payer Health Care Can't Work  -  ‎Aug 11, 2009‎
The first breakthrough was Tagamet, the first antacid that actually reduced the production of stomach acid. Smith, Kline & French -- now GlaxoSmithKline Minyanville.com

ЗаболÑ?ваниÑ? на хранопровода- Ñ?имптоми, възможни уÑ?ложнениÑ? и лечение  -  ‎Aug 21, 2009‎
Такива извеÑ?тни лекарÑ?тва Ñ?а например: Nexium, Tagamet, Omeprazole, Prevacid и други. Те Ñ?е предпиÑ?ват за период от време 6- 8 меÑ?еца, а понÑ?кога по-дълго. България Сега

Calcium curious: How much is enough?  -  ‎Jul 13, 2009‎
People taking medications that reduce stomach acid -- such as the proton-pump inhibitors (Prevacid, Prilosec) or the H2 blockers (Tagamet, Zantac) -- should Newsday

Virtues and Character Markings of Future Leaders  -  ‎Jul 9, 2009‎
His lab is famous for forming action-learning teams that create discoveries like Tagamet and Beta blockers. He modestly described his leadership style, Huffington Post

'You'll see him smilin',' but is he really?  -  ‎Jun 26, 2009‎
We were shocked when told monstrous quantities of Maalox and Tagamet are poured regularly into dolphins' holding tanks to help alleviate physical and mental Sonoma Valley Sun

Les antiacides augmentent les risques de fracture  -  ‎Jun 22, 2009‎
Très communs, les médicaments Prilosec, Prevacid, Nexium et ceux vendus sans ordonnance, Pepcid, Tagamet et Zantac, soulagent les reflux gastro-œsophagiens. El Moudjahid

Plavix: alcuni pazienti rispondono meno bene all'antiaggregante ...  -  ‎Jun 29, 2009‎
Zantac, Pepcid, Tagamet e Axid ) o gli antiacidi, interferiscano con l'attività antiaggregante piastrinica del Clopidogrel. ( Xagena Medicina ) XagenaSalute

Medicines turn off acid pump  -  ‎Mar 30, 2009‎
Those medicines are Tagamet, Pepcid, Axid and Zantac, all over-the-counter medicines. You have to take approaches to stomach-acid control that aren't South Coast Today

GLENN'S STRATEGIES FOR WELL-BEING: How drugs work in the body  -  ‎Apr 2, 2009‎
Or let's say it's in the evening and he takes some Tagamet (which is available over-the-counter) for heartburn and a Valium to help him sleep. Eurweb.com

論傳統中醫發展困境的根本解決辦法  -  ‎Apr 11, 2009‎
...西方社會�智慧財産的�障�是��餘力,以西藥中胃藥泰胃美(Tagamet)爲例,它的開發�程耗資巨�,投注無數人力與心血,但是一旦開發�功,因爲�得專利權的�障, NOWnews

Stimulus bill a horribly priced ‘placebo’  -  ‎Feb 28, 2009‎
I went in to my quack, who prescribed some Tagamet. I bought a jar of these pills for $35, which seemed like a fortune, but the pain went away after I’d The Tennessean

Plavix-heartburn drug combo found fatal  -  ‎Mar 4, 2009‎
They also reported the absence of such correlation in patients taking plavix along with non-PPI drugs such as Zantac, Pepcid, Axid and Tagamet; they however PRESS TV

Gastrointestinal drug gets 'black box' warning  -  ‎Mar 6, 2009‎
There are prescription-strength drugs for reflux that reduce gastric acid rather than increase motility, such as the H2 blockers Zantac and Tagamet and the Los Angeles Times

타는듯한 ì†?쓰림 ì‹?사습관 ê³ ì³?ë?¼  -  ‎Mar 9, 2009‎
...위산 ìƒ?성ì?„ 줄ì?´ëŠ” 치료제로는 타가멧(Tagamet HB), 펩시드(Pepcid AC), 액시드(Axid AR), ìž°íƒ?(Zantac 75) 등ì?´ 있는ë?° ì?´ë“¤ 성분ì?€ 처방전용보다 용량ì?„ 반으로 미주 한국일보

Tomar anticoagulantes y medicamentos para la acidez gástrica ...  -  ‎Mar 10, 2009‎
...debemos considerar probablemente recetar a estos pacientes bloqueadores de H2 [como Zantac o Tagamet] en lugar de inhibidores de la bomba de protones, Info7

Heart Burn: Causes and Treatments  -  Feb 3, 2009
Another good over the counter treatment for heart burn is an H-2-receptor blocker, such as Tagamet HB or Pepcid AC. These medicines work from the antacids, 마�드스�츠올림피아드,

FDA Reviewing Side Effects of Plavix with Prilosec and Other Drugs  -  Jan 27, 2009
Other drugs that can be used to reduce stomach acid, such as H2 blockers like Zantac, Pepcid, Tagamet and Axid, or antacids to not appear to interfere with AboutLawsuits.com

Certain acid reflux medication may be dangerous for some heart ...  -  Jan 30, 2009
Other reflux medications such as Tagamet and Zantac did not affect heart attack risk because they do not interfere with PLAVIX. WWAY NewsChannel 3,

What treatments work for GORD?  -  Jan 21, 2009
Some common names (and brand names) are ranitidine (Zantac), nizatidine (Axid), famotidine (Pepcid) and cimetidine (Tagamet). You can buy some of these guardian.co.uk,

What treatments work for warts?  -  Jan 21, 2009
...[11] Cimetidine (brand name Tagamet) is a drug that's usually used for people with stomach ulcers. The theory behind this treatment is that it helps your guardian.co.uk,

Courier & Press employees, friends share favorite recipes  -  Dec 23, 2008
I won't lie: You'll probably want to take a Tagamet just before or just after the meal. It's spicy, and you're going to want a lot of it. Henderson Gleaner,

Use yohimbe under doctor's care  -  Dec 1, 2008
There is also the option of taking over-the-counter cimetidine (Tagamet HB). Although studies of cimetidine have had mixed results, some readers report that Jackson Clarion Ledger,

Digestive difficulties can be simply treated  -  Dec 16, 2008
...such as the proton pump inhibitors Aciphex, Nexium, Prevacid, Prilosec, and Protonix and the H2 blockers Axid, Pepcid, Tagamet, and Zantac. Newsday,

Top 10 Global Personal Care Products Makers  -  Dec 4, 2008
Some of GSK’s brands are Tagamet, Flonase, Aquafresh, etc. The other companies in the above list Svenska Cellulosa Aktiebolaget, Kao Corporation and L’Oreal Seeking Alpha,

Gradeons: Prescribing placebos  -  Nov 30, 2008
There is also the option of taking over-the-counter cimetidine (Tagamet HB). Although studies of cimetidine have had mixed results, some readers report that Houston Chronicle,

7 Common Digestive Problems and How to End Them  -  Nov 19, 2008
...such as the proton pump inhibitors Aciphex, Nexium, Prevacid, Prilosec, and Protonix and the H2 blockers Axid, Pepcid, Tagamet, and Zantac. U.S. News & World Report,

A new heads-up for GERD sufferers  -  Oct 30, 2008
Today, we have histamine-2 blockers, such as Pepcid, Tagamet and Zantac, which make the stomach produce less acid. We also have proton pump inhibitors USA Weekend

Dr. Murray Feingold: Burning issues of reflux  -  Nov 17, 2008
Medications that reduce type 2 histamine are Tagamet, Pepcid, Axil and Zantac. Then came proton-pump inhibitors. The proton-pump is needed in order for acid Taunton Daily Gazette,

Saving on the drugs bill  -  Nov 10, 2008
There is a precedent here: the first generation acid suppressants (Tagamet and Zantac) can now be bought over the counter. Patients who take the latest Irish Times,

Treat mouth tenderly to reduce canker sores  -  Nov 10, 2008
The heartburn drug cimetidine (Tagamet) also may help relieve symptoms. For larger, more painful canker sores, there are several prescription medicines that The Star-Ledger - NJ.com,

McCain Misreads the Mood--Again  -  Oct 15, 2008
All of which is great news for the makers of Prozac and Tagamet--but sucks big time for the rest of us. When people are brassed off, they want a fighter. The Plank on TNR.com,

Easy tips to beat heartburn  -  Sep 29, 2008
H2 blockers (some brand names: Pepcid, Tagamet, Zantac) reduce the amount of stomach acids. Several are available without a prescription. The News International,

From the Los Angeles Times  -  Oct 7, 2008
Zantac 75, Pepcid AC, Tagamet HB and Axid AR are some of the products available without a prescription. A second medication is the proton pump inhibitor, Baltimore Sun,

Nothing funny with economy  -  Oct 14, 2008
I sat down to write something humorous and instead I’m sitting here gobbling Tagamet and Pepcid AC tablets like they were M and M’s while I wonder how I’m Reporter-Times,

US Food & Drug Administration Approved the use of REYATAZ(R ...  -  Oct 1, 2008
Prevacid ® (lansoprazole), Prilosec ® (omeprazole), Protonix ® (pantoprazole), Axid ® (nizatidine), Pepcid AC ® (famotidine), Tagamet ® (cimetidine), WELT ONLINE,

Many medications, diseases can cause vitamin B12 deficiency  -  Oct 5, 2008
...and others) or H2 receptor blockers (Tagamet, Pepcid, Zantac), which are used to treat gastroesophageal reflux disease (GERD) and peptic ulcer disease. KPCnews.com,

ОблыÑ?ение и методы борьбы Ñ? ним  -  Oct 8, 2008
Циметидин (Tagamet) - антагониÑ?Ñ‚ гиÑ?таминового Ð?2-рецептора, который иÑ?пользуетÑ?Ñ? длÑ? лечениÑ? Ñ?зв желудка и 12-перÑ?тной кишки. Лоцман,

Somnus Therapeutics, Inc. Announces Initial Board of Directors  -  16 Sep 2008
Gary Cupit's pharmaceutical industry experience also includes many product launches (eg, Tagamet(R), Androderm(R) and Hycamtin(R)). MarketWatch

Do some foods stop drugs working?  -  Sep 12, 2008
For example, cimetidine (Tagamet and Zantac) helps to treat stomach ulcers and heartburn by lowering the acidity in our stomachs. This can have the knock-on Times Online,

Jinx McAllister: For a woman like me, baldness is more than a ...  -  Sep 11, 2008
I have tried injections of steroids into my scalp, Rogaine, topical creams, massive doses of Tagamet and acupuncture. Nothing worked, but I did learn from IdahoStatesman.com,

Health Officials Say Campus Bay Safe for Current Use, Not Homes  -  Aug 21, 2008
...cited the interactions “between certain pesticides and herbicides and Tagamet,� a prescription medication commonly prescribed for ulcers. Berkeley Daily Planet,

Xìu Tại Thuốc  -  Aug 29, 2008
Cimetidine (Tagamet) trị bệnh bao tử. Có thể gây rối loạn cương hoặc làm cho vú nở to ra. - Nhóm thuốc � phiện (Opioids) chống đau nhức có thể làm giảm Take2Tango

Drug blockbusters: a measure of pharma success  -  11 Aug 2008
...after morphing into SmithKline & Becton and then SmithKline & Beecham) that had the first blockbuster, an anti-ulcer drug called Tagamet (cimetadine). WTN News,

Hooray for Blockbuster Drugs  -  Aug 1, 2008
Take Tagamet, the granddaddy of all blockbusters. Until the 1970s, peptic ulcers could cause severe stomach lacerations, bleeding, and even death; City Journal,

Heartburn Drugs Can Speed Up Aging  -  Jul 25, 2008
Two types of drugs, proton-pump inhibitors (such as Prevacid and Prilosec) and H2 blockers (Tagamet, Zantac, and Pepcid) are very effective at reducing Stop Aging Now,

Tastes Nasty, But the upshot is it works!  -  Jul 22, 2008
In large doses this substance can lead to some serious stuff for people on ery common drugs, such as Tagamet and birth control pills. In very large doses, Examiner.com

Going-Concern Statement  -  Aug 6, 2008
Pepcid AC(R) (famotidine), Tagamet(R) (cimetidine), or Zantac(R) (ranitidine), Advair(R) (fluticasone propionate and salmeterol inhalation powder), FOXBusiness

Dr. Mayer Eisenstein Offers a New Paradigm for Acid Reflux by ...  -  Aug 7, 2008
To relieve their symptoms people turn to Tums®, Rolaids®, Zantac®, Tagamet®, or the more dangerous, PPIs [Proton Pump Inihibitors] (Nexium®, Prevacid®, NewsReleaseWire.com (press release)

The dinner club  -  Jul 16, 2008
Another time she prepared a hot and spicy Thai beef dish that sent Pat Neylon reaching for the Tagamet. "Oh yeah, that was the night Pat had fire in his Columbia Daily Tribune,

销售å?‡å†’å??牌è?¯å“?296万元  -  Jul 21, 2008
...�年11月9日,公安人员在石�区将陈������抓获,并缴获Tagamet 中山日报,

Heartburn drug "cured" her warts  -  Jun 8, 2008
A: The cimetidine (Tagamet) "cure" for warts was first written about in the early 1990s. This was an unusual use; Tagamet was a popular prescription drug Seattle Times,

Popular Prescriptions Can Cause Drug Dependence  -  Jun 12, 2008
A: The cimetidine (Tagamet) "cure" for warts was first written about in the early 1990s. This was an unusual use; Tagamet was a popular prescription drug RedOrbit,

Medications Can Rob Body and Cause Zinc Deficiency  -  Jul 1, 2008
These include antacids, antibiotics birth control pills, hormone replacement drugs for hot flashes, acid-blocking drugs (Nexium, Prilosec, Tagamet, Zantac, RedOrbit,

From Infectious Diseases to Cancer: 60 Years of Pharmaceutical Growth  -  Jun 30, 2008
...gastrointestinal (ulcers, which spawned the first blockbuster drug Tagamet) and arthritis (non-steroidal anti-inflammatories) commanded our attention. MidwestBusiness.com,

From infectious diseases to cancer - 60 years of pharmaceutical ...  -  Jun 30, 2008
...spawning the first blockbuster drug Tagamet) and arthritis (non-steroidal anti-inflammatories otherwise known as NSAID’s) commanded our attention. WTN News,

Hidden costs of private drug insurance  -  Jun 1, 2008
Older heartburn drugs like Tagamet or Zantac, and other drugs available over the counter at a fraction of the price often get bypassed if you have a private Common Ground.ca,

AGS: A Little Anticholinergic Burden Can Be Disabling  -  May 6, 2008
Patients who were taking one moderately anticholinergic drug, such as cimetidine (Tagamet), or two mildly anticholinergic drugs -- such as furosemide and MedPage Today,

ASK DR. WEIL: Counting on creatine?  -  May 13, 2008
Using creatine with drugs that can affect the kidneys, such as Tagamet and ibuprofen, could potentially increase the risk of kidney damage. Lancaster Newspapers,

Health Q&A on GERD  -  May 10, 2008
Over-the-counter antacids such as Zantac or Tagamet are recommended for mild symptoms. For more severe cases, prescription medications are available. Appleton Post Crescent,

Somnus Therapeutics, Inc. Announces CEO and Formation of Executive ...  -  May 22, 2008
CEO and Director Gary Cupit, PharmD, has more than 20 years of pharmaceutical industry experience, including several product launches (eg, Tagamet ® Business Wire (press release),

NPS Appoints Dr. Bo Joelsson as Head of Clinical Research  -  May 13, 2008
He has led the clinical development of several major gastrointestinal products, including Tagamet® (cimetidine), Prilosec® (omeprazole), Business Wire (press release),

Brand Names/Synonyms:
Tagamet is also known by the following brand names and/or synonymsAcibilin; Acinil; CIMETIDINE A/AB; Carbamazapine; Cimal; Cimetag; Cimetidine; Cimetidine Hcl; Cimetum; Dyspamet; Edalene; Eureceptor; FPF 1002; Gastromet; Peptol; Tagamet; Tagamet Hb; Tagamet Hb 200; Tametin; Tratul; Ulcedin; Ulcedine; Ulcerfen; Ulcimet; Ulcofalk; Ulcomedina; Ulcomet; Ulhys

Drug Category:
Tagamet is categorized under the following by the FDA: Analgesics; Anti-ulcer Agents; Adjuvants; Histamine Antagonists; ATC:A02BA01

Dosage Forms:
Tablets; Oral solution

Absorption:
Rapid 60-70%

Interactions:
-->Interactions for Cimetidine:

Tagamet, apparently through an effect on certain microsomal enzyme systems, has been reported to reduce the hepatic metabolism of warfarin-type anticoagulants, phenytoin, propranolol, nifedipine, chlordiazepoxide, diazepam, certain tricyclic antidepressants, lidocaine, theophylline and metronidazole, thereby delaying elimination and increasing blood levels of these drugs.

Clinically significant effects have been reported with the warfarin anticoagulants; therefore, close monitoring of prothrombin time is recommended, and adjustment of the anticoagulant dose may be necessary when Tagamet is administered concomitantly. Interaction with phenytoin, lidocaine and theophylline has also been reported to produce adverse clinical effects.

However, a crossover study in healthy subjects receiving either Tagamet 300 mg q.i.d. or 800 mg h.s. concomitantly with a 300 mg b.i.d. dosage of theophylline (Theo-Dur®, Key Pharmaceuticals, Inc.) demonstrated less alteration in steady-state theophylline peak serum levels with the 800 mg h.s. regimen, particularly in subjects aged 54 years and older. Data beyond 10 days are not available. (Note: All patients receiving theophylline should be monitored appropriately, regardless of concomitant drug therapy.)

Dosage of the drugs mentioned above and other similarly metabolized drugs, particularly those of low therapeutic ratio or in patients with renal and/or hepatic impairment, may require adjustment when starting or stopping concomitantly administered Tagamet to maintain optimum therapeutic blood levels.

Alteration of pH may affect absorption of certain drugs (e.g., ketoconazole). If these products are needed, they should be given at least 2 hours before cimetidine administration.

Additional clinical experience may reveal other drugs affected by the concomitant administration of Tagamet.

 




Chemical IUPAC Name:
1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine

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