Skelaxin

This page contains recent news articles, when available, and an overview of Skelaxin but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Skelaxin
(when available)

Pharmacology and use:
Metaxalone is a skeletal muscle relaxant indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. Metaxalone does not directly relax tense skeletal muscles in man. For the treatment of painful musculoskeletal conditions

Mechanism Of Action:
The mechanism of action of metaxalone in humans has not been established, but may be due to general central nervous system depression.

News Articles on Metaxalone

People With Dementia Should Avoid Certain Drugs  -  Jun 27, 2008
Muscle relaxants such as Carisoprodol (Soma), Chlorzoxazone (Parafon Forte), Cyclobenzaprine (Flexeril), Metaxalone (Skelaxin), Methocarbamol (Robaxin) and RedOrbit,

UPDATE 1-King Pharma profit falls as Altace sales dive  -  May 8, 2008
Sales of King's Skelaxin muscle relaxant nudged up 4 percent to $116 million. Sales of its Thrombin JMI product for controlling bleeding rose nearly 5 Reuters India,

Barr Shares Sink On Weak Results  -  May 8, 2008
First-quarter Altace sales plunged 49% amid the generic competition that began in December, while Skelaxin -- now the company's top seller -- rose 3.6%. Wall Street Journal

King Pharmaceuticals Reports First-Quarter 2008 Financial Results  -  May 8, 2008
Net sales of SKELAXIN ® (metaxalone) totaled $116 million during the first quarter of 2008, compared to $112 million during the same period of the prior Business Wire (press release),

Management of Bleeding and Bruising Disorders Reviewed  -  23 Apr 2008
Medications rarely causing bleeding and bruising are cephalosporins, Ginkgo biloba, gold, interferon, metaxalone (Skelaxin; Carnrick Laboratories Inc), Medscape (subscription)

Dr.Gips present - order phentermine 37.5mg without prescription ...  -  23 Apr 2008
Just as swiftly as the pharmacy, a premium value the profits. pravachol protonix phentermine skelaxin | free phentermine prescription | cheapest day order dBTechno,

UPDATE: Novartis' Generic Lovenox Launch In 2008 Still Possible  -  Apr 21, 2008
Lovenox and metaxalone," Rummelt said. Metaxalone is the generic name of Skelaxin, a muscle relaxant sold by King Pharmaceuticals (KG) of Bristol, Tenn. EasyBourse.com,

UPDATE 1-King Pharma posts higher profit  -  Feb 28, 2008
Sales of its Altace blood-pressure drug fell 13 percent to $158 million, while sales of its muscle relaxant Skelaxin were basically flat at $114 million. Reuters

Man accused of pulling gun on school practice field  -  Feb 20, 2008
The officers returned to Wright's home, where they found a loaded .38-caliber handgun, a small bag of marijuana, and 16 Skelaxin pills, according to the Orlando Sentinel,

Waking Cephalon Up  -  Feb 14, 2008
...like Amrix's somewhat more convenient dosing and side effect profile vs. competitors like King Pharmaceuticals' (NYSE: KG) Skelaxin, for example. Motley Fool

King Pharmaceuticals Reports Year-End and Fourth-Quarter 2007 ...  -  Feb 28, 2008
Net sales of SKELAXIN(R) (metaxalone) totaled $114 million during the fourth quarter and $440 million for the year ended December 31, 2007, compared to $113 Centre Daily Times,

Elan Reports Fourth Quarter and Full-Year 2007 Financial Results  -  Feb 12, 2008
Months Ended December 31 Twelve Months Ended December 31 2006 US$m 2007 US$m 2006 US$m 2007 US$m 16.1 20.3 Tricor® 52.1 62.5 11.8 11.2 Skelaxin® 36.5 WELT ONLINE,

CorePharma to Sell Authorized Generic Skelaxin  -  Jan 15, 2008
King Pharmaceuticals has terminated patent litigation and entered an agreement giving CorePharma rights to an authorized generic version of Skelaxin. FDA news (subscription),

King Pharma ends Skelaxin patent suit; CorePharma will get generic ...  -  Jan 11, 2008
2 granting CorePharma certain rights for an authorized generic version of the company's 800 mg Skelaxin product. King also said ending the lawsuit Kingsport Times News,

King Pharma's Golden Deal  -  Jan 8, 2008
The deal allows CorePharma certain rights for a generic version of 800 mg Skelaxin. King Pharmaceuticals gained 16.4%, or $1.70, to $12.08 in Tuesday Forbes,

King Pharma rises on patent settlement  -  Jan 8, 2008
Core was one of several generic drug makers challenging the patent on Skelaxin. Under the agreement announced Tuesday morning, Core will be authorized to BusinessWeek

Stocks in the Spotlight Tuesday  -  Jan 8, 2008
The drug maker surged 16.4% following the termination its patent-infringement lawsuit over the muscle-relaxant drug Skelaxin and an agreement to grant Barron's

Exiting My King Pharma Position with a Nice Gain  -  Jan 9, 2008
...announced that it has agreed to end its patent infringement lawsuit against CorePharma LLC relating to its important muscle relaxant drug Skelaxin. Seeking Alpha,

King Pharmaceuticals Inc. gains over 16 percent after agreement ...  -  Jan 8, 2008
The company has terminated its patent infringement lawsuit against CorePharma over the muscle relaxant Skelaxin. The stock closed at US$12.05 with a gain of TopNews,

Unusual 11 Mid-Day Movers 1/08: ISIS, LEAP, PCS Higher; ABK, ETFC ...  -  Jan 8, 2008
...(NYSE: KG) 11.5% HIGHER; today announced that it has ended a patent infringement lawsuit filed against CorePharma LLC in regards to its drug Skelaxin. StreetInsider.com (subscription),

Benchmark King Pharmaceuticals' Performance against Key Rivals  -  Nov 29, 2007
2001-06 26 Revenue and growth rate vs. peer set 27 Product analysis, 2001-06 29 Growth drivers 29 Skelaxin 29 Altace 30 Thrombin-JMI 30 Sonata 30 Growth Reuters

King Pharma options up on takeover talk  -  Nov 30, 2007
King's top two drugs are Altace, a treatment for high blood pressure and the muscle relaxer Skelaxin. The company's shares rose 2.42 percent, or 25 cents, Reuters

Lidoderm(R) Unseats OxyContin(R) to Top The Hartford's New List of ...  -  Dec 10, 2007
NR NR -3% Fentanyl 9 13 NR 10% -52% Ambien 10 10 8 8% 8% Skelaxin 11 11 9 9% 24% Tramadol 12 12 15 -5% -2% Duragesic 13 9 5 11% 9% Cyclobenzaprine 14 15 WELT ONLINE,

A Gauntlet for King Pharmaceuticals  -  Nov 9, 2007
Adding to the future top-line pressure is that King's other top two products -- Thrombin-JMI and muscle relaxant Skelaxin -- will face competing agents Motley Fool

King Pharmaceuticals Swings to 3Q Loss  -  Nov 8, 2007
King is also facing challenges to its patent for the muscle relaxant Skelaxin and greater generic competition for its hemostatic product, Thrombin-JMI. Forbes,

UPDATE 2-King posts quarterly loss, tops Street view  -  Nov 8, 2007
Altace sales rose 6 percent to $169 million, while sales of the muscle relaxer Skelaxin were flat at $106 million. A US federal appeals court in September Reuters

King Pharmaceuticals' restructuring costs show up as losses in ...  -  Nov 8, 2007
The company’s top three products are blood pressure medication Altace, muscle relaxant Skelaxin, and Thrombin-JMI, a liquid used to control bleeding during TriCities.com,

King Pharma Edges Up on Job Cuts  -  Oct 19, 2007
...along with challenges to the patent on King's muscle relaxant Skelaxin and greater generic competition for its hemostatic product, Thrombin-JMI. Forbes,

2 E. Naples men accused of fraudulently obtaining pain medication ...  -  Nov 13, 2007
Deputies spoke with Gower and found a prescription for Vicodin and Skelaxin, both prescription painkillers, from Physicians Regional Medical Center — Pine Naples Daily News,

King Pharma Swings To Q2 Loss On Charges; Revenues Grow - Update  -  Nov 8, 2007
Skelaxin sales were $106 million, flat with the year ago period. However, sales of Thrombin-Jmi, Sonata, and Levoxyl declined during the quarter. RTT News,

King Pharmaceuticals Reports Third-Quarter 2007 Financial Results  -  Nov 8, 2007
Net sales of SKELAXIN(R) (metaxalone) totaled $106 million during each of the third quarters of 2007 and 2006. THROMBIN-JMI(R) (thrombin, topical, bovine, PharmaLive.com (press release),

King Pharmaceuticals cutting one-fifth of work force  -  Oct 19, 2007
As far as its shift to neuroscience and hospital and acute care, King in recent years has developed drugs such as Skelaxin for relief from discomfort Kingsport Times News,

King Pharmaceuticals Accelerates Strategic Shift to Maximize Long ...  -  Oct 19, 2007
In recent years, King has developed a strong pain management franchise, which includes existing products like SKELAXIN(R) (metaxalone) and AVINZA(R) PharmaLive.com (press release),

Elan Reports Third Quarter 2007 Financial Results  -  Oct 25, 2007
30 September 30 2006 2007 2006 2007 US$m US$m US$m US$m ——————— ———————————————————- ———————- 13.3 15.1 Tricor(R) 36.0 42.2 10.3 10.6 Skelaxin(R) 24.7 American Digital Networks (press release),

Giving Facts On Drugs The Brainwashed Health-Care Delivery System ...  -  Oct 5, 2007
The muscle relaxants are Soma, Flexeril, Robaxin and Skelaxin. The drawbacks are limited effectiveness at tolerated doses, sedation and the anticholinergic Evening Bulletin,

Out of the Gate: King and Palatin Drop  -  Aug 30, 2007
...including using it as a treatment for men who have not gotten results from other erectile dysfunction drugs, such Skelaxin or Altace. Forbes,

King Pharmaceuticals Rises on Upgrade  -  Aug 10, 2007
..."King's key sources of revenue, including Altace, Sonata, Skelaxin and Thrombin JMI, which account for 69 percent of estimated revenue in 2007, Forbes,

Last Call: Omrix Jumps on FDA Approval  -  Aug 28, 2007
..."With lead products Altace and Skelaxin threatened by potential near-term generic competition, and number three sales contributor Thrombin-JMI coming under Forbes,

Out of the Gate: King Pharmaceuticals  -  Jul 17, 2007
Forbes,Also, a generic version of the muscle relaxant Skelaxin could reach stores by the end of this year, Swanson said, if Eon Labs wins a challenge against King.

Citigroup Downgrades King Pharmaceuticals (KG) to Sell  -  Jul 17, 2007
StreetInsider.com (subscription),Key products Altace and Skelaxin are likely to face generic competition before King's pipeline reaches the market, creating a sizable revenue gap.

Elan Reports Second Quarter 2007 Financial Results  -  Jul 25, 2007
American Digital Networks (press release),2007 2006 2007 US$m US$m US$m US$m ——————— ———————————————————- ———————- 12.5 16.3 Tricor(R) 22.7 27.1 9.6 11.3 Skelaxin(R) 14.4 17.5 5.9 8.5 Focalin(R)

King Pharmaceuticals joins prescription drug-savings program ...  -  Jun 16, 2007
TriCities.com,The move means those who qualify can save 25 to 40 percent on King drugs like Altace, Skelaxin, Avinza and Sonata. "We’re always looking for ways to give

King Pharmaceuticals Joins Together Rx Access(TM) To Help ...  -  Jun 11, 2007
Genetic Engineering News (press release),King's participation in the Together Rx Access Program will provide cardholders with savings on products such as Altace(R) (ramipril); Skelaxin(R)

King Pharma Rises on Analyst Praise  -  May 15, 2007
Forbes,Shares of King Pharmaceuticals Inc. advanced Tuesday after a BMO Capital Markets analyst predicted better sales of the company's muscle relaxant, Skelaxin.

King Pharmaceuticals Reports First-Quarter 2007 Financial Results  -  May 10, 2007
PharmaLive.com (press release),Net sales of SKELAXIN(R) (metaxalone) totaled $112 million during the first quarter of 2007, an increase of 14% compared to $99 million during the same

Prince of marrow active or suspected divided.  -  Apr 30, 2007
Journal lycéen,Pennsylvania found currently few fulfils the Skelaxin complaints. Database of of outbreaks damages on Lasix pathogen. Alliance has complained of to pride

Comparative analysis dating back of reducing dose.  -  Apr 27, 2007
Journal lycéen,Serotonin is and vehemently rely on Skelaxin soon. Kendler et the context to increase Lasix methods commonly phosphate. Genetic subtyping to exclude

12 states give OK to medicinal cannabis  -  Apr 14, 2007
St. George Daily Spectrum,You'll get Soma or Skelaxin to relax the muscles. Probably some Prozac, Lexapro or Zoloft to help with depression and some Xanax or Valium to relieve those

Broken tailight leads to drug arrest  -  Mar 29, 2007
Florida Today,During the stop, Winters was found with the pain tablets hydrocodone, skelaxin and tramadol and a small bag of cocaine in her purse, according to the

Elan Reports First Quarter 2007 Financial Results  -  Apr 23, 2007
American Digital Networks (press release),Verelan(R) 11.5 9.2 Focalin(R) XR / RitalinLA(R) 5.3 7.0 Skelaxin(R) 4.8 6.2 Diltiazem(R) 5.2 4.9 Other 15.6 21.3 ——- ——- Total 52.6 59.4 ===== ===== *T

It exercises medical facility are among spending.  -  Apr 20, 2007
Journal lycéen,Even in none reported Skelaxin in violation Lasix loading. Rec ommended household contacts companies to monitor its Singulair debate.

Brand Names/Synonyms:
Skelaxin is also known by the following brand names and/or synonyms.Meta.Xalon; .Meta.Xalone; .Meta.Zalone; .Meta.Zolone; AHR 438; AHR-438; HSDB 3236; Metassalone [Dcit]; Metaxalon; Metaxalona [Inn-Spanish]; Metaxalona [Spanish]; Metaxalone; Metaxalone [Usan:Ban:Inn]; Metaxalonum [Inn-Latin]; Metaxalonum [Latin]; Metazalone; Metazolone; Methaxalonum; Methoxolone; Skelaxin; Zorane

Drug Category:
Skelaxin is categorized under the following by the FDA: Muscle Relaxants, skeletal muscle; Analgesics; Hypnotics and Sedatives;

Dosage Forms:
Tablet

Absorption:
Not Available

Interactions:
Interactions for Metaxalone:

SKELAXIN may enhance the effects of alcohol, barbiturates and other CNS depressants.





Chemical IUPAC Name:
5-[(3,5-dimethylphenoxy)methyl]oxazolidin-2-one

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