Skelaxin

This page contains recent news articles, when available, and an overview of Skelaxin but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Skelaxin (when available)

Pharmacology and use:
Metaxalone is a skeletal muscle relaxant indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. Metaxalone does not directly relax tense skeletal muscles in man. For the treatment of painful musculoskeletal conditions

Mechanism Of Action:
The mechanism of action of metaxalone in humans has not been established, but may be due to general central nervous system depression.

News Articles on Metaxalone

Analyst upgrades, downgrades and initiations: AMZN, RS, JNJ, NFLX ...  -  20 Apr 2009
UBS upgraded King Pharmaceuticals (NYSE: KG) to Buy from Sell based on expectations that Sandoz will settle patent litigation regarding Skelaxin after last BloggingStocks

Analysts' Upgrades, Downgrades: Citigroup  -  20 Apr 2009
Expect a higher probability of Skelaxin settlement with SGP. Quicksilver Resources downgraded to sector perform from outperform and price target reduced to TheStreet.com

King Pharma shares rise on Goldman recommendation  -  ‎Apr 8, 2009‎
She said it's also possible that generic competition for King's muscle relaxant Skelaxin will be delayed, as the company could come to a settlement with Forbes

高盛将国王制�?�评级定为强力买进  -  ‎Apr 8, 2009‎
...这�?分�?师进一步指出，国王制�?�肌肉�?�弛剂Skelaxin的仿制�?�竞争�?�能延迟，该公�?��?�能�?�将与诺�?�制�?�达�?�??议。Skelaxin的专利�?�已于今年一月到期。中国证券网

高盛將國王製藥評級定為強力買進  -  ‎Apr 8, 2009‎
...這�?分�?師進一步指出，國王製藥肌肉鬆弛劑Skelaxin的仿製藥競爭�?�能延�?�，該公�?��?�能�?�將與諾�?�製藥�?��?�?�議。Skelaxin的專利權已於今年一月到期。新浪網

Wachovia Upgrades King Pharmaceuticals (KG) to Outperform  -  ‎Mar 16, 2009‎
Wachovia analyst says, "KGâ€™s emerging pipeline of abuse-deterrent opioids could overcome the top line pressure stemming from generic entry of Skelaxin and StreetInsider.com (subscription)

King Reports Fourth-Quarter Loss on Alpharma Purchase  -  ‎Feb 26, 2009‎
...“It’s too early to get constructive on King, given that Embeda and Remoxy approval timing is in doubt and as generic Skelaxin could be approved Bloomberg

Seeking Gain From Pain  -  ‎Mar 3, 2009‎
Second, King recently lost a legal challenge to two patents covering the muscle relaxant Skelaxin, its current best-seller. In January, a federal district Motley Fool

10-K: KING PHARMACEUTICALS INC  -  ‎Mar 2, 2009‎
6407128 and 6683102, two patents related to Skelaxin(R). The Order was issued without the benefit of a hearing in response to Eon Labs' motion for summary MarketWatch (press release)

Drug Stocks Are Bargains After Plunge: John Dorfman (Correct)  -  ‎Mar 9, 2009‎
For example, King’s patents on its muscle relaxant Skelaxin, its biggest selling drug, were found invalid. Its experimental morphine capsule Embeda hasn’t Bloomberg

King slashes jobs after Alpharma buyout, Skelaxin ruling  -  04 Feb 2009
The company plans to eliminate 380 sales jobs and 140 corporate posts in light of the Skelaxin ruling. Job cuts tied to the Alpharma takeover will involve SmartBrief,

King Pharmaceuticals Cuts 22% of Work Force  -  Feb 3, 2009
The Skelaxin-related job cuts involve 380 field sales positions and 140 corporate positions. Additionally, 240 people will be laid off tied to King's $1.6 Wall Street Journal

King Pharma slides on Skelaxin patent verdict  -  Jan 21, 2009
...based company said a US District Court in New York issued a summary judgment that the two patents on the muscle relaxant Skelaxin were not valid. Forbes,

Buy skelaxin  -  Jan 17, 2009
Weird buy skelaxin in should buy skelaxin imitrex active sedative buy skelaxin phentermine for pharmacokinetics cheapest blood buy skelaxin Zooloft buy Griggs County Courier,

King Pharmaceuticals to lay off 70 at Bristol headquarters  -  Jan 30, 2009
Citing a court decision last week that could hasten the entry of a generic competitor to its muscle relaxer Skelaxin, a King Pharmaceuticals spokesman said Kingsport Times News,

BRIEF-King Pharma says plans to appeal Skelaxin judgment  -  Jan 21, 2009
The copying, republication or redistribution of Reuters News Content, including by framing or similar means, is expressly prohibited without the prior Forbes,

BRIEF-King Pharma says plans to appeal Skelaxin judgment  -  Jan 21, 2009
Interactive Investor Trading Limited, trading as "Interactive Investor", is authorised and regulated by the Financial Services Authority. Interactive Investor,

Stocks on the move: Allegheny, American Axle, Cree, Jabil, PNC  -  Jan 21, 2009
The pharmaceutical company said the US District Court for the Eastern District of New York issued an order invalidating two patents relating to Skelaxin. San Mateo County Times,

Preview from Europe: Another Bear Market Bounce, or Bottoming?  -  Jan 22, 2009
Elan (ELN) says its Tricor/Trilipix franchise grew strongly in Q4 2008, but patent expiration is looming for its Skelaxin drug. Seeking Alpha,

Business briefs: Jan. 22  -  Jan 21, 2009
...based company said a US District Court in New York issued a summary judgment that the two patents on the muscle relaxant Skelaxin were not valid. Knoxville News Sentinel,

킹, 특허 잃고 대대�? �?�력�?축  -  Feb 3, 2009
...킹 파마슈티컬스(King Pharmaceuticals)가 주력 제품�?� 근육 �?�완제 ‘스켈�?�신’(Skelaxin, metaxalone)�?� 특허를 잃고 대대�? �?�력�?축�?� 실시한다. 디지틀보사,

King Pharmaceuticals extends Alpharma buyout offer  -  Dec 22, 2008
A key goal of the deal is to expand King's pain drug franchise, which consists of the chronic pain treatment Avinza and the muscle relaxant Skelaxin. MSNBC

Alpharma accepts King's $1.6 billion bid  -  Nov 30, 2008
A key goal of the deal is to expand King's pain drug franchise, which consists of the chronic pain treatment Avinza and the muscle relaxant Skelaxin. Belleville News Democrat,

キングファーマ�?�サンドを骨格筋弛緩剤�?�特許侵害�?��??訴  -  Dec 8, 2008
...キング・ファーマシューティカルズ�?��?Pharmaceutical IP Holdings�?�ら独�?�的ライセンスを�?��?��?��?�る骨格筋弛緩剤「スケラキシン（Skelaxin）�?�?��?��?��?��?サンド�?�後発 IP NEXT ニュース,

King Pharma swings to profit in Q3 on lower charges, despite ...  -  Nov 6, 2008
Altace net sales were $30 million, sharply down from $169 million in the third quarter of 2007, while Skelaxin sales were $110 million, marginally up from RTT News,

Earnings Preview: King Pharmaceuticals  -  Nov 5, 2008
Positive factors for this quarter include the recent patent settlement for Skelaxin and higher sales from Avinza. Negative risks to earnings is continued Seeking Alpha,

Man robbed while walking down street  -  Nov 19, 2008
...the theft of her prescription medication from her home, including Diazepam, Endocet and Skelaxin (valium, pain medication and a muscle relaxer). Richmond Register,

King Pharmaceuticals Posts Better-Than-Expected Third Quarter Profits  -  Nov 6, 2008
King Pharmaceuticals posted higher profits than expected by analysts, due to sales of its injectable products such as skeletal muscle relaxant Skelaxin. Network Médica,

King Pharmaceuticals Inc. Q3 2008 Earnings Call Transcript  -  Nov 7, 2008
However, we continue to see consistent performance from our key promoted products including Skelaxin, Thrombin-JMI and Avinza. Seeking Alpha,

King Pharmaceuticals Reports Third-Quarter 2008 Financial Results  -  Nov 6, 2008
Net sales of SKELAXIN ® (metaxalone) totaled $110 million during the third quarter of 2008, compared to $106 million during the same period of the prior istockAnalyst.com (press release),

King rises after analyst upgrades on lower risk  -  Oct 9, 2008
The analyst said King stock could be strong if the company keeps patent protection on its muscle relaxant Skelaxin through 2009, or if regulators appear to Forbes,

King Extends Bid for Rival  -  Oct 13, 2008
Alpharma makes pain drugs Kadian and Flector, while King's products include the Skelaxin muscle relaxant. This copy is for your personal, non-commercial use Wall Street Journal

Alpharma Rejects Sweetened Bid  -  Sep 27, 2008
King, the Bristol, Tenn., maker of Skelaxin muscle relaxant and other drugs, initially proposed to acquire Alpharma for $33 a share in August. Wall Street Journal

国王制�?�评级�?�至买进股价大涨10%  -  Oct 9, 2008
...戴维斯指出，如果能将肌肉�?�弛剂Skelaxin 新浪网,

國王制藥評級�?�至買進股價大漲10%  -  Oct 11, 2008
...戴維斯指出，如果能將肌肉蟆弛劑Skelaxin 新浪網,

When pain arrives - and help does not  -  Sep 14, 2008
Skelaxin, a muscle relaxant, made me sleepy and nauseous. Percocet worked fairly well, but only for three hours at a time. Even the over-the-counter pills Boston Globe,

Alpharma Rejects King's Advances  -  Aug 22, 2008
King's key revenue drivers include Avinza, which treats chronic pain, and Skelaxin, a muscle relaxant. The drugs had sales of $653 million and $440 million, Forbes,

Walk the Portland way  -  Sep 4, 2008
Skelaxin," by Zachary Howard is on view at the Corduroy Surf Boutique. While you're there you can listen to DJ Mr. Dereloid spin his signature beat. MaineToday.com,

Police: Man tries to swallow evidence  -  Aug 22, 2008
He also had an orange pill bottle containing several pills each of Naproxen and Skelaxin -- both prescription pain killers -- and Seroquel, a prescription The Union Leader,

King's Unstoppable Urge to Merge  -  Sep 12, 2008
Hypertension treatment Altace has begun to face generic competition, and muscle relaxant Skelaxin will face generic competition sooner than expected. Motley Fool

King says Alpharma rebuffed a $1.4B buyout bid  -  Aug 22, 2008
King's key products include Avinza, which treats chronic pain and Skelaxin, a muscle relaxant. The drugs had sales of $653 million and $440 million, The Associated Press

Blotter: Accident kills one, injures one in Shreveport  -  Aug 27, 2008
A search of his vehicle led to the discovery of opened bottles of alcoholic beverages and a pill bottle containing one Skelaxin tablet, two Flexeril tablets Shreveport Times,

UPDATE 1-King Pharma profit below view; stock plunges  -  Aug 7, 2008
Sales of the muscle relaxant Skelaxin fell roughly 1 percent to $107 million. King shares fell to $10.50 in premarket trading, down from a Wednesday close Reuters

King Pharmaceuticals Reports Second-Quarter 2008 Financial Results  -  Aug 7, 2008
Net sales of SKELAXIN(R) (metaxalone) totaled $107 million during the second quarter of 2008, compared to $108 million during the same period of the prior Trading Markets (press release),

People With Dementia Should Avoid Certain Drugs  -  Jun 27, 2008
Muscle relaxants such as Carisoprodol (Soma), Chlorzoxazone (Parafon Forte), Cyclobenzaprine (Flexeril), Metaxalone (Skelaxin), Methocarbamol (Robaxin) and RedOrbit,

UPDATE 1-King Pharma profit falls as Altace sales dive  -  May 8, 2008
Sales of King's Skelaxin muscle relaxant nudged up 4 percent to $116 million. Sales of its Thrombin JMI product for controlling bleeding rose nearly 5 Reuters India,

Barr Shares Sink On Weak Results  -  May 8, 2008
First-quarter Altace sales plunged 49% amid the generic competition that began in December, while Skelaxin -- now the company's top seller -- rose 3.6%. Wall Street Journal

King Pharmaceuticals Reports First-Quarter 2008 Financial Results  -  May 8, 2008
Net sales of SKELAXIN ® (metaxalone) totaled $116 million during the first quarter of 2008, compared to $112 million during the same period of the prior Business Wire (press release),

Management of Bleeding and Bruising Disorders Reviewed  -  23 Apr 2008
Medications rarely causing bleeding and bruising are cephalosporins, Ginkgo biloba, gold, interferon, metaxalone (Skelaxin; Carnrick Laboratories Inc), Medscape (subscription)

Dr.Gips present - order phentermine 37.5mg without prescription ...  -  23 Apr 2008
Just as swiftly as the pharmacy, a premium value the profits. pravachol protonix phentermine skelaxin | free phentermine prescription | cheapest day order dBTechno,

UPDATE: Novartis' Generic Lovenox Launch In 2008 Still Possible  -  Apr 21, 2008
Lovenox and metaxalone," Rummelt said. Metaxalone is the generic name of Skelaxin, a muscle relaxant sold by King Pharmaceuticals (KG) of Bristol, Tenn. EasyBourse.com,

UPDATE 1-King Pharma posts higher profit  -  Feb 28, 2008
Sales of its Altace blood-pressure drug fell 13 percent to $158 million, while sales of its muscle relaxant Skelaxin were basically flat at $114 million. Reuters

Man accused of pulling gun on school practice field  -  Feb 20, 2008
The officers returned to Wright's home, where they found a loaded .38-caliber handgun, a small bag of marijuana, and 16 Skelaxin pills, according to the Orlando Sentinel,

Waking Cephalon Up  -  Feb 14, 2008
...like Amrix's somewhat more convenient dosing and side effect profile vs. competitors like King Pharmaceuticals' (NYSE: KG) Skelaxin, for example. Motley Fool

King Pharmaceuticals Reports Year-End and Fourth-Quarter 2007 ...  -  Feb 28, 2008
Net sales of SKELAXIN(R) (metaxalone) totaled $114 million during the fourth quarter and $440 million for the year ended December 31, 2007, compared to $113 Centre Daily Times,

Elan Reports Fourth Quarter and Full-Year 2007 Financial Results  -  Feb 12, 2008
Months Ended December 31 Twelve Months Ended December 31 2006 US$m 2007 US$m 2006 US$m 2007 US$m 16.1 20.3 Tricor® 52.1 62.5 11.8 11.2 Skelaxin® 36.5 WELT ONLINE,

CorePharma to Sell Authorized Generic Skelaxin  -  Jan 15, 2008
King Pharmaceuticals has terminated patent litigation and entered an agreement giving CorePharma rights to an authorized generic version of Skelaxin. FDA news (subscription),

King Pharma ends Skelaxin patent suit; CorePharma will get generic ...  -  Jan 11, 2008
2 granting CorePharma certain rights for an authorized generic version of the company's 800 mg Skelaxin product. King also said ending the lawsuit Kingsport Times News,

King Pharma's Golden Deal  -  Jan 8, 2008
The deal allows CorePharma certain rights for a generic version of 800 mg Skelaxin. King Pharmaceuticals gained 16.4%, or $1.70, to $12.08 in Tuesday Forbes,

King Pharma rises on patent settlement  -  Jan 8, 2008
Core was one of several generic drug makers challenging the patent on Skelaxin. Under the agreement announced Tuesday morning, Core will be authorized to BusinessWeek

Stocks in the Spotlight Tuesday  -  Jan 8, 2008
The drug maker surged 16.4% following the termination its patent-infringement lawsuit over the muscle-relaxant drug Skelaxin and an agreement to grant Barron's

Exiting My King Pharma Position with a Nice Gain  -  Jan 9, 2008
...announced that it has agreed to end its patent infringement lawsuit against CorePharma LLC relating to its important muscle relaxant drug Skelaxin. Seeking Alpha,

King Pharmaceuticals Inc. gains over 16 percent after agreement ...  -  Jan 8, 2008
The company has terminated its patent infringement lawsuit against CorePharma over the muscle relaxant Skelaxin. The stock closed at US$12.05 with a gain of TopNews,

Unusual 11 Mid-Day Movers 1/08: ISIS, LEAP, PCS Higher; ABK, ETFC ...  -  Jan 8, 2008
...(NYSE: KG) 11.5% HIGHER; today announced that it has ended a patent infringement lawsuit filed against CorePharma LLC in regards to its drug Skelaxin. StreetInsider.com (subscription),

Benchmark King Pharmaceuticals' Performance against Key Rivals  -  Nov 29, 2007
2001-06 26 Revenue and growth rate vs. peer set 27 Product analysis, 2001-06 29 Growth drivers 29 Skelaxin 29 Altace 30 Thrombin-JMI 30 Sonata 30 Growth Reuters

King Pharma options up on takeover talk  -  Nov 30, 2007
King's top two drugs are Altace, a treatment for high blood pressure and the muscle relaxer Skelaxin. The company's shares rose 2.42 percent, or 25 cents, Reuters

Lidoderm(R) Unseats OxyContin(R) to Top The Hartford's New List of ...  -  Dec 10, 2007
NR NR -3% Fentanyl 9 13 NR 10% -52% Ambien 10 10 8 8% 8% Skelaxin 11 11 9 9% 24% Tramadol 12 12 15 -5% -2% Duragesic 13 9 5 11% 9% Cyclobenzaprine 14 15 WELT ONLINE,

Brand Names/Synonyms:
Skelaxin is also known by the following brand names and/or synonyms.Meta.Xalon; .Meta.Xalone; .Meta.Zalone; .Meta.Zolone; AHR 438; AHR-438; HSDB 3236; Metassalone [Dcit]; Metaxalon; Metaxalona [Inn-Spanish]; Metaxalona [Spanish]; Metaxalone; Metaxalone [Usan:Ban:Inn]; Metaxalonum [Inn-Latin]; Metaxalonum [Latin]; Metazalone; Metazolone; Methaxalonum; Methoxolone; Skelaxin; Zorane

Drug Category:
Skelaxin is categorized under the following by the FDA: Muscle Relaxants, skeletal muscle; Analgesics; Hypnotics and Sedatives;

Dosage Forms:
Tablet

Absorption:
Not Available

Interactions:
Interactions for Metaxalone:

SKELAXIN may enhance the effects of alcohol, barbiturates and other CNS depressants.

Chemical IUPAC Name:
5-[(3,5-dimethylphenoxy)methyl]oxazolidin-2-one

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