Serevent

This page contains recent news articles, when available, and an overview of Serevent but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Serevent (when available)

Pharmacology and use:
Salmeterol, a highly selective beta(2)-agonist, is used to treat asthma and to prevent bronchospasm in patients with reversible obstructive airway disease. For the treatment of Asthma and chronic obstructive pulmonary disease (COPD).

Mechanism Of Action:
Salmeterol's long, lipophilic side chain binds to exosites near beta(2)-receptors in the lungs and on bronchiolar smooth muscle, allowing the active portion of the molecule to remain at the receptor site, continually binding and releasing. Beta(2)-receptor stimulation in the lung causes relaxation of bronchial smooth muscle, bronchodilation, and increased bronchial airflow.

News Articles on Salmeterol

Treating COPD Early Improves Outcomes  -  ‎Aug 28, 2009‎
Patients were also receiving the bronchodilator salmeterol (Serevent) or the anticholinergic Spiriva. The researchers found that adding Daxas to treatment U.S. News & World Report

Early Treatment off COPD May Increase Life Expectancy  -  ‎Aug 29, 2009‎
Those patients who were randomly assigned to receive Daxas also received the bronchodilator Serevent (salmeterol) or Spiriva. HealthNews

Experts Question Study's Asthma Drug Safety Claim  -  ‎Aug 19, 2009‎
The medications involved are called long-acting beta agonists, and they include Serevent (salmeterol, GlaxoSmithKline) and Foradil (formoterol, Schering). ABC News

Balancing the Benefits and Risks of Inhaled Long-Acting Beta ...  -  ‎Apr 15, 2009‎
1 The FDA responded by requiring a black-box warning on the Serevent and Advair labels, and in July 2005 the SMART results and those of a phase 4 study of New England Journal of Medicine (subscription)

AstraZeneca Experiences Approval Delays with Symbicort for Children  -  ‎Apr 6, 2009‎
Other LABAs, such as Serevent and Foradil, do not contain a steroid. Those taking a corticosteroid, either alone or with a LABA, increased their risk of Newsinferno.com

GSK courts diabetes drug war with hefty price cut  -  ‎Apr 2, 2009‎
Asthma medicines (Serevent) have gone down by an average of 62 per cent. GSK said some children medicines in this category have gone down to Sh548 per month Business Daily Africa

Statins good for asthma too  -  ‎Mar 15, 2009‎
...long-acting beta-agonists, such as Serevent, whose actions can persist for 12 hours or longer; and leukotriene modifiers, such as Singulair, Los Angeles Times

Asthma inhalers: Which one's for you?  -  ‎Mar 2, 2009‎
They include salmeterol (Serevent) and formoterol (Foradil). Corticosteroids. Used long term to prevent asthma attacks, these medications include WTHI

How Much Did Biases in the Study of Chronic Obstructive Pulmonary ...  -  ‎Mar 16, 2009‎
Other: DH Au (Assessing the Impact of Recent Updates for Advair and Serevent Special Issues Board). 1. Anthonisen NR, Connett JE, Enright PL, Manfreda J; Annals of Internal Medicine

Massachusetts Bans Industry Gifts to Docs  -  ‎Mar 12, 2009‎
I avoided problems with avandia, vioxx, and serevent using that technique. Pharmaceuticals are part of our health care costs. How will our employers and tax Wall Street Journal Blogs

ASMA: FDA, DUBBI SULLA SICUREZZA DI 4 FARMACI  -  ‎Feb 27, 2009‎
Gli studi clinici con il solo Serevent rappresentavano quasi 43.000 pazienti. Dall'analisi e' emerso che i pazienti in eta' pediatrica (4-11 ann ) e gli AGI - Agenzia Giornalistica Italia

Advisory committee recommends restrictions on Serevent, Foradil ...  -  Jan 30, 2009
...the panels recommended that the FDA restrict the use of two single-ingredient asthma medications, Serevent and Foradil (see table for panel’s vote). AAP News (subscription)

Schmidt & Clark, LLP Announces Launch of Advair, Foradil, Serevent ...  -  Jan 10, 2009
Michael E. Schmidt, Managing Partner of Schmidt & Clark, LLP, has noticed an alarming number of inquiries to the firm related to Advair, Foradil, Serevent PR Leap (press release),

Treating your asthma from day to day  -  Jan 21, 2009
Available at http://www.fda.gov/medwatch/SAFETY/2003/serevent.htm (accessed on 15 October 2007). US Food and Drug Administration. guardian.co.uk,

Salmeterol or formoterol from an inhaler as an extra treatment  -  Jan 21, 2009
The brand name for salmeterol is Serevent. Brand names for formoterol include Foradil and Oxis. Your child takes them using an inhaler. guardian.co.uk,

Combination of drugs found most effective asthma treatment  -  Jan 11, 2009
Inhalers such as Serevent Diskus and Foradil Aerolizer, which contain only a long-acting beta agonist, are not good choices for treating asthma. American Medical News (subscription)

I lékárníci dávají „slevu“  -  Feb 3, 2009
Jak se platilo Znojmo Lékárna Nemocnice (krajská): Plavix 75 MG: doplatek 95,Serevent diskus: nemají Detralex 30 tablet: doplatek 150,Lékárna U Radnice MF DNES,

U lékaře platit chtějí, v lékárně ne  -  Feb 3, 2009
Porovnání doplatků za vybrané léky na předpis Lékárna Masarykovy nemocnice Ústí nad Labem (bez poplatku) plavix 75 mg 203 K�? serevent diskus nevedou MF DNES,

Új csataterek az asztmakezelésben  -  Jan 27, 2009
A Serevent és a Foradil egyedüli hatóanyaga egy-egy LABA, a Seretide és a Symbicort azonban tartalmaznak inhalálható kortikoszteroidot is. Weborvos,

천�?·COPD 치료�? 세레타�?�드 밀리나  -  Jan 19, 2009
...�?한, 노바티스가 개발 중�?� 새로운 LABA '�?�다카테롤'(indacaterol)�?� '세레벤트'(Serevent, salmeterol)보다 �??기능�?� 개선시키는 것으로 �?�가�?�며, 디지틀보사,

FDA Panel: Serevent, Foradil Risks Outweigh Benefits  -  Dec 11, 2008
The panel said the risks of GlaxoSmithKline PLC 's (GSK) asthma drug Serevent as well as Novartis AG's (NVS) and Schering-Plough Corp. CNNMoney.com

Asthma medications: What you need to know  -  Dec 19, 2008
In December, a panel of experts from the Food and Drug Administration recommended to ban two drugs from being used for asthma: salmeterol (Serevent) and Modern Medicine,

Warning Given on Use of 4 Popular Asthma Drugs, but Debate Remains  -  Dec 5, 2008
Glaxo also sells Serevent, which had $538 million in sales last year. Symbicort is made by AstraZeneca and Foradil by Novartis. Whatever the committee’s New York Times,

Vaccine may block recurrence of lung cancer  -  Dec 16, 2008
A panel of experts last week said the drugs Serevent and Foradil should be banned as asthma treatments, but that Advair and Symbicort should continue to be Belleville News Democrat,

FDA advisers weigh risks of asthma drugs  -  Dec 10, 2008
At issue are four inhaler medications: Advair, Foradil, Serevent and Symbicort. Within the FDA, opinions appear to be divided. The Associated Press

FDA Advisers Consider Safety of Long-Acting Beta Agonist Inhalers  -  Dec 10, 2008
...(See: "Salmeterol (Serevent) Increases Serious Adverse Events in Chronic Asthma" ) David Graham, MD, associate director for science and medicine in the MedPage Today,

FDA Documents Say Drugs Increase Risk of Asthma-Related Death  -  Dec 5, 2008
Glaxo-Smith-Kline, which markets the salmeterol-containing products Advair and Serevent, defended the safety of its asthma drugs in its own set of briefing MedPage Today,

Asthma, breast cancer and the flu  -  Dec 11, 2008
It is recommending that the drugs Foradil and Serevent no longer be used to treat asthma. The two drugs work by relaxing airway muscles, but that may mask 7Online.com,

US FDA panel says two asthma drugs risky  -  Dec 11, 2008
N: Quote, Profile, Research) Serevent and Novartis AG's (NOVN.VX: Quote, Profile, Research) Foradil pose serious risks that outweigh their benefits for Reuters UK,

Healthwatch for December 8, 2008  -  Dec 8, 2008
If you suffer from asthma, federal health officials are recommending you stay away from the drug known as Serevent. Researchers say the drug produces a WBOY-TV,

News Minute: It's up to Bush...Daschle gets nod for health job ...  -  Dec 11, 2008
...a top-selling medication. Outside experts advising the Food and Drug Administration say Foradil and Serevent no longer should be used for asthma. Fox 12 Boise,

Some asthma meds. do not benefit kids  -  Dec 10, 2008
...(NBC) - The asthma medications Serevent and Foradil don't have a clear benefit in children, according to a review of published studies. WWLP 22News,

Cancer likely to be #1 killer by 2030  -  Dec 10, 2008
A recent review found inhalers, like Advair, Serevent, Foradil and Symbicort, do improve lung function for children, but had provided no change in improving NECN,

AP NewsAlert  -  Dec 11, 2008
WASHINGTON (AP) — FDA advisers recommend that drugs Serevent and Foradil no longer be used for asthma. The Associated Press

Health Highlights: Dec. 7, 2008  -  Dec 7, 2008
Dr. Katharine Knobil, global clinical vice president for GlaxoSmithKline, which markets both Advair and Serevent, told the Times that the FDA's drug-safety Forbes,

Experts Highlight New Tool as a Timely Addition to Asthma Treatment  -  Dec 10, 2008
Symbicort, Serevent and Foradil, Dr. Philip Marcus, Chief, Division of Pulmonary Medicine, St. Francis Hospital, and Dr. James Wolfe, of Allergist, MarketWatch

Obama will inherit new endangered-species rules  -  Dec 11, 2008
Outside experts advising the Food and Drug Administration said that Foradil and Serevent no longer should be used for asthma. Winston-Salem Journal,

US FDA Panel Recommends Restrictions on Two Asthma Drugs  -  Dec 15, 2008
A US Food and Drug Administration (FDA) panel has called for restrictions on two asthma drugs, Serevent and Foradil and said the widely prescribed drug TopNews,

Are You Taking the Right Asthma Medication?  -  Dec 9, 2008
Examples include Serevent or Flovent, and they are known as bronchodilators — they relax the smooth muscles in the walls of the airways. FOXNews

Monday Health News: December 15  -  Dec 15, 2008
GlaxoSmithKline PLC's Serevent and Novartis AG's Foradil where the two drugs ruled to pose serious health risks by the FDA panel on Thursday, December 11th. Chiropractic News (press release)

FDA: asthma drugs pose increased risks  -  Dec 5, 2008
The safety of the drugs -- Serevent manufactured by GlaxoSmithKline PLC, Symbicort made by AstraZeneca, and Foradil from Novartis AG -- will be reviewed by Trading Markets (press release),

Around the nation  -  Dec 5, 2008
But a less widely used medication, Serevent, had a significantly higher rate of complications when compared with older treatments, the Food and Drug Arizona Daily Star,

FDA review: Long-acting asthma drugs pose serious risks  -  Dec 9, 2008
...a panel of outside experts this week to evaluate the safety of AstraZeneca's Symbicort, Novartis AG's Foradil and GlaxoSmithKline's Advair and Serevent. SmartBrief,

Paris jewelry robbers net $108 million  -  Dec 6, 2008
But a less widely used medication, Serevent, had a significantly higher rate of complications when compared to older treatments, the Food and Drug Fort Wayne Journal Gazette,

Business Briefly  -  Dec 5, 2008
But a less widely used medication, Serevent, had a significantly higher rate of complications when compared to older treatments, the Food and Drug LubbockOnline.com,

FDA review: Long-acting asthma drugs pose serious risks  -  Dec 8, 2008
...a panel of outside experts this week to evaluate the safety of AstraZeneca's Symbicort, Novartis AG's Foradil and GlaxoSmithKline's Advair and Serevent. SmartBrief,

UK at a Glance-UK Stocks -- Factors to watch on Dec 12  -  Dec 11, 2008
Two asthma drugs, GlaxoSmithKline's Serevent and Novartis AG's Foradil, pose serious risks that outweigh their benefits for treating adults, adolescents and Hemscott,

Swiss stocks - Factors to watch on Dec 12  -  Dec 11, 2008
Evidence of asthma-related deaths and serious complications have led a US advisory panel of experts to warn against continued use of Glaxo's Serevent and Interactive Investor,

FDA review: Long-acting asthma drugs pose serious risks  -  Dec 8, 2008
...a panel of outside experts this week to evaluate the safety of AstraZeneca's Symbicort, Novartis AG's Foradil and GlaxoSmithKline's Advair and Serevent. SmartBrief,

Nation/World briefs  -  Dec 10, 2008
An unusually large panel of some 30 medical and scientific advisers will vote today on whether the risks of the drugs -- Advair, Foradil, Serevent and DetNews.com,

AP Business NewsBrief at 9:35 am EST  -  Dec 5, 2008
The agency analyzed reams of clinical data on four drugs: Advair, Foradil, Serevent, and Symbicort. All carry strong warnings already, but the findings TMCnet

مخاطر من استخدام مح�?زات بيتا لمعالجة الربو  -  Dec 24, 2008
يذكر ان لجنة استشارية من خارج الهيئة قد صوتت على سحب مستحضري (Serevent) و (Foradil) مع الإبقاء على المستحضرين (Seretide) و (Symbicort). باب,

FDA sugere proibição dos fármacos Serevent e Foradil  -  Dec 16, 2008
A autoridade norte-americana que regula os medicamentos (FDA) sugere a proibição do uso dos medicamentos Serevent (GlaxoSmithKline) e Foradil (Novartis) Fábrica de Conteúdos,

Recomiendan retirar dos fármacos contra el asma de efecto extendido  -  Dec 12, 2008
Expertos independientes que asesoran a la Administración de Fármacos y Alimentos (FDA) dijeron que Foradil y Serevent no deberían seguir siendo usados El Nuevo Herald,

EEUU ve riesgos en fármacos para el asma, pide consejo a panel  -  Dec 5, 2008
Entre los LABA se encuentran Advair y Serevent de GlaxoSmithKline Plc, Symbicort de AstraZeneca Plc y Foradil de Novartis AG, que en Estados Unidos Reuters América Latina,

Les États-Unis recommandent le retrait de deux médicaments pour l ...  -  Dec 11, 2008
Les conseillers médicaux et scientifiques de la Food and Drug Administration (FDA) ont recommandé jeudi que les médicaments Foradil et Serevent soient La Presse Canadienne,

FDA pode banir drogas para asma  -  Dec 13, 2008
Especialistas da FDA (agência norte-americana que regulamenta a aprovação de alimentos e fármacos) sugeriram a proibição do uso dos medicamentos Serevent e 24Horas News,

FDA-Gutachter fordern Verbot bestimmter Asthmamedikamente  -  Dec 12, 2008
Washington – Ein Gutachtergremium empfiehlt der Food and Drug Administration (FDA), den Einsatz der Medikamente Serevent® und Foradil® beim Asthma Deutsches Ärzteblatt,

Голо�?ование FDA запретило два лекар�?тва от а�?тмы  -  Dec 19, 2008
Эк�?перты определили, что ри�?к от и�?пользовани�? лекар�?твенный �?ред�?тв Серевент (Serevent) и Форадил (Foradil), и�?пользуемых дл�? ингал�?ций при а�?тме, МЕДСТРИМ.РУ - кон�?ультации врачей, ново�?ти медицины,

ASTRAZENECA: FDA-KOMMITTÉ STÖDER SYMBICORT (OMS)  -  Dec 11, 2008
Däremot röstade kommittén att riskerna överstiger fördelarna med Glaxosmithklines astmaläkemedel Serevent. Även Novartis astmaläkemedel Foradil fick tummen Dagens Nyheter,

衛生署�??醒氣喘用藥之安全性  -  Dec 15, 2008
...衛生署核准使立穩(Serevent �?��?�醫療網,

GlaxoSmithKline "underweight" - JP Morgan Securities  -  Dec 15, 2008
Das Komitee habe jedoch gegen eine Monotherapie mit "Serevent" gestimmt, weshalb die FDA die Asthma-Indikation vermutlich vom Label des Produkts nehmen Stock World,

FDA-Mitarbeiter fordern Verbot von Asthmamedikamenten  -  Dec 9, 2008
Dieses Risiko war für drei einzelne Medikamente (Foradil®, Serevent®, Symbicort®) nachweisbar, das Signifikanzniveau wurde aber nur für Serevent® erreicht, Deutsches Ärzteblatt,

FDA�?문위�?, '어드바�?�어'OK, '세레벤트' NO  -  Dec 11, 2008
11�?� 열린 FDA �?문위�?회�?서 �?��?들�?� ''아드바�?�어(Advair)'와 '심비코트(Symbicort)'는 천�?치료�? 사용�?� 지지한 반면 '�?��?�딜(Foradil)'과 '세레벤트(Serevent)' 메디게�?�트뉴스,

- Ikke bruk for mye  -  Dec 12, 2008
Torsdag skrev ABC Nyheter at legemiddelverket i USA, Food and Drug Administration (FDA), advarer mot de to astmamedisinene Foradil og Serevent. ABC Nyheter,

FDA Gremium empfiehlt Rückzug von Novartis Asthma Medikament  -  Dec 5, 2008
Dasselbe empfahl die Behörde einer internen Mitteilung vom Freitag zufolge auch für Serevent des britischen Herstellers GlaxoSmithKline(GSK.L: Kurs). Reuters Deutschland,

LÄKEMEDEL:FÖRHÖJD RISK FÖR BEHOV AV VÅRD VID ASTMABEHANDL -FDA  -  Dec 5, 2008
En statistiskt signifikant förhöjd risk observerades i studier med Glaxosmithklines Serevent. Även för Astrazenecas Symbicort och Novartis Foradil var Dagens Nyheter,

“GSK '어드바�?�어'등 천�?약 사�? 위험 까지�?  -  Dec 7, 2008
...�?헬스코리아뉴스】GSK�?� '어드바�?�어(Advair)' '세레벤트(Serevent)' 아스트�?�제네카�?� '심비코트(Symbicort)' 노바티스�?� '�?��?�딜(Foradil)'등 지�?형 베타2 천�? 헬스코리아뉴스,

AKTIEN EUROPA/Ausblick: Talfahrt erwartet - Negatives aus Auto ...  -  Dec 12, 2008
Die Risiken der beiden Mittel Foradil (Novartis) und Serevent (GSK) würden deren Nutzen bei der Behandlung von Erwachsenen, Jugendlichen und Kindern Handelszeitung Online,

Besorgnis über Asthma-Medikamente  -  Dec 16, 2008
Es folgten Warnhinweise, die auch auf andere Präparate mit der gleichen Wirkstoffgruppe ausgedehnt wurden - darunter "Serevent", "Advair", "Foradil" und Deutschlandradio,

Brand Names/Synonyms:
Serevent is also known by the following brand names and/or synonymsAeromax; Arial; Astmerole; CHEMBANK1801; SEREVENT; Salmetedur; Salmeterol; Salmeterol Xinafoate; Salmeterol [Usan:Ban:Inn]; Salmeterolum [Latin]; Serevent; [Usan:Ban:Inn]

Drug Category:
Serevent is categorized under the following by the FDA: Bronchodilator Agents; Sympathomimetic; Adrenergic beta-Agonists;

Dosage Forms:
METERED-DOSE (AEROSOL); POWDER

Absorption:
Because of the small therapeutic dose, systemic levels of salmeterol are low or undetectable after inhalation of recommended doses (50 mcg of salmeterol inhalation powder twice daily). Following chronic administration of an inhaled dose of 50 mcg of salmeterol inhalation powder twice daily, salmeterol was detected in plasma within 5 to 45 minutes in 7 patients with asthma; plasma concentrations were very low, with mean peak concentrations of 167 pg/mL at 20 minutes and no accumulation with repeated doses.

Interactions:
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Chemical IUPAC Name:
2-(hydroxymethyl)-4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]-phenol

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