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ReglanThis page contains recent news articles, when available, and an overview of Reglan but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.Overview: Reglan (when available) Metoclopramide, although chemically related to procainamide, does not possess local anesthetic or antiarrhythmic properties. Metoclopramide is used to enhance GI motility, to treat diabetic gastroparesis, as an antinauseant, and to facilitate intubation of the small bowel during radiologic examination. Metoclopramide may be used to treat chemotherapy-induced emesis and as a radiosensitizing agents in the treatment of non-small cell lung carcinoma and glioblastomas in the future. For the treatment of gastroesophageal reflux disease (GERD) Mechanism Of Action: Metoclopramide inhibits gastric smooth muscle relaxation produced by dopamine, therefore increasing cholinergic response of the gastrointestinal smooth muscle. It accelerates intestinal transit and gastric emptying by preventing relaxation of gastric body and increasing the phasic activity of antrum. Simultaneously, this action is accompanied by relaxation of the upper small intestine, resulting in an improved coordination between the body and antrum of the stomach and the upper small intestine. Metoclopramide also decreases reflux into the esophagus by increasing the resting pressure of the lower esophageal sphincter and improves acid clearance from the esophagus by increasing amplitude of esophageal peristaltic contractions. Metoclopramide's dopamine antagonist action raises the threshold of activity in the chemoreceptor trigger zone and decreases the input from afferent visceral nerves. Studies have also shown that high doses of metoclopramide can antagonize 5-hydroxytryptamine (5-HT) receptors in the peripheral nervous system in animals. News Articles on Metoclopramide The Mulligan Law Firm is Evaluating Reglan® Injury Cases and ... - Aug 29, 2009 The Mulligan Law Firm announces that it is evaluating and investigating cases where usage of the prescription drug Reglan® has led to the development of a Advertiser Talk Reglan Patient Describes Side Effects - Aug 18, 2009 Casa Grande, AZ: Donna H. (name withheld) says she expected her doctor would tell her about any serious Reglan side effects, so she was surprised to learn Lawyers and Settlements Does the Pot Pill Work? - Aug 4, 2009 Since Marinol did nothing for me the only help my doctors can give me is Reglan/Metoclopramide. When he handed my Reglan prescription to me my doctor said, CBS News Twitches, Shakes and Tremors: What's Causing Your Symptoms or Side ... - Aug 25, 2009 Reglan: Metoclopramide sold under brand names Reglan, Octamide, and Maxolon, is used to treat heartburn in people with gastroesophageal reflux disease US Recall News (press release) LegalView Announces Reglan Information Portal Launch - Aug 8, 2009 The newest addition to the LegalView family is a Reglan information portal, providing information concerning potential Reglan side effects which could PR-USA.net (press release) Breastfeeding 101: What things can you take/eat to increase your ... - Aug 4, 2009 Ritchie says those include Motilum and Reglan. Nurse Practitioner Barb Dehn says also remember to increase your fluid intake! Examiner.com Men Who Breastfeed - Aug 13, 2009 ...still that it might occur spontaneously in a man NOT on a prolactin-increasing drug (for example, Reglan -- a common acid reflux medicine -- does this, Momlogic.com Kathy's Caregiver Notes - Aug 5, 2009 Reglan should help with digestion and nausea. Lasix (furosemide) is a diuretic. And Silvadene is a cream for skin sores. We are canceling the Zantac because EmpowHer Drug-induced diarrhea can be deadly - Aug 5, 2009 ..."He decided to quit taking his beloved Cialis. Lo and behold! His digestive tract improved: No more Questran, no more Reglan, Librax or. San Bernardino Sun Fondo sojero: el PJ quiere más aportes para comunas - Aug 11, 2009 El 30 %, de conformidad a la ley provincial Nº 7457 y modificatorias (que reglan la distribución de la Coparticipación Federal), a todos los municipios y ElLitoral.com الصداع.. المخاوÙ? ووسائل العلاج - 14 Jul 2009 كما قد يعزز دواء «ميتوكلوبراميد» metoclopramide (ريغلان Reglan) من تأثير الأدوية غير الستيرويدية. وعندما تكون هناك Øاجة للأدوية الموصوÙ?Ø© طبيا، يلجأ الكثير النيلين Reglan Adverse Events Events Jump Dramatically - Jul 7, 2009 The adverse events associated with Reglan involve a muscle disorder tardive dyskinesia. The increase precedes Reglan's black box warning. InjuryBoard.com Reglan recall is another reason to try herbal treatment - Jun 29, 2009 The primary active ingredient in Reglan, metoproclamide, is supposed to increase stomach muscle movement to aid digestion, Recently, it has been linked to Examiner.com Quick Study - Jun 29, 2009 THIS STUDY analyzed data on 81703 infants, including 3458 whose mothers had taken Reglan (metoclopramide) to relieve nausea and vomiting during the first Washington Post Reglan Users Beware, Temporary Reflux Relief May Lead to Incurable ... - Jun 26, 2009 Both groups make up the estimated 2 million users who were prescribed and may be currently taking Reglan. Reglan is the brand name for metoclopramide. InjuryBoard.com Attorney Weighs in on Reglan Investigation - Jun 25, 2009 Austin, TX: If you thought the number of people who reported suffering Reglan side effects was small, you might have to think again. Lawyers and Settlements A Little of This, A Little of That - Jul 2, 2009 I still get abdominal bloating and discomfort when I eat and have low-grade nausea not completely controlled by the Reglan. It's finally starting to make my EmpowHer Hanging In There - Jun 18, 2009 We are going to try Reglan on the theory that my entire digestive tract just isn't moving like it's supposed to. I thought I was going to have the EmpowHer "Deaths From Medical Marijuana v. 17 FDA Approved Drugs" from ... - Jul 3, 2009 The drugs use in the comparison that are prescribed in lieu of cannabis were the antiemetics Compazine, Reglan, Marinol, Zofran, Anzemet, Kytril and Tigan; Daily Kos Recién en agosto resolverÃan si Pereyra queda o no en libertad - Jul 7, 2009 24.390 y la 25.430 (reglan los plazos de prisión preventiva) establecen que un imputado debe ser liberado al cumplir 3 años de encierro sin sentencia. Diario de Cuyo FDA requires black box warning-Reglan may cause permanent injury! - Apr 14, 2009 Reglan and other metoclopramide containing drugs are used to treat gastroesophageal reflux disease (GERD) and gastroparesis. Both medical conditions are NewYorkInjuryNews Motion Filed to Consolidate Reglan Tardive Dyskinesia Lawsuits - Apr 8, 2009 The plaintiffs in all of the known tardive dyskinesia lawsuits filed against the makers of Reglan and other Metoclopramide-containing drugs, AboutLawsuits.com The Mulligan Law Firm is Evaluating and Investigating Possible ... - Apr 14, 2009 The Mulligan Law Firm is very pleased to announce that Reglan® has been added to its extensive list of prescription-based drug injury cases that it is Emediawire (press release) Three Days on Reglan, A Lifetime of Pain - Apr 13, 2009 Osceola Mills, PA: Patients who have suffered from Reglan side effects know how serious those complications can be. Now that a link has been found between Lawyers and Settlements Black Box Warning for Reglan | InjuryBoard Philadelphia - Mar 31, 2009 Reglan will soon get a boxed warning of the risks of long term and high dose use, as recently required by the FDA. Reglan is one of a group of drugs InjuryBoard.com Putting Drug Research in Legal Jeopardy - Apr 3, 2009 But then she filed suit in California state court against Wyeth, the inventor of Reglan, though she had never taken Wyeth’s product. City Journal Court Rules Brand-Drug Makers Not Liable for Generics’ Labeling - Mar 30, 2009 Pharma to warn patients about potential risks associated with taking generic versions of the heartburn drug Reglan manufactured by other companies. FDA news (subscription) Drug-Induced Dementia and Delirium Common in Seniors But Often ... - Apr 1, 2009 ...metoclopramide (Reglan); and drugs in the benzodiazepine category such as popular sleeping pills Ambien (zolpidem) and Lunesta (eszopiclone). Common Dreams (press release) Denunciado penalmente el alcalde DÃazgranados Pinedo por el ex ... - Apr 12, 2009 ...generara una interinidad en la Gerencia de la entidad, burlando claras e imperativas normas que reglan el proceso de escogencia aludido y procederá al El Informador - Santa Marta El dictador - Apr 5, 2009 Asà se explica que el proyecto de cada dictador es destruir las relaciones polÃticas que reglan la vida de cada nación, imponiendo su cultura, Analítica Reglan, Similar Heart Burn Drugs to Have Black Box For Movement ... - Feb 27, 2009 Heart burn drugs that contain metoclopramide, including Reglan Tablets, Reglan Oral Disintegrating Tablets, Metoclopramide Oral Solution and Reglan Newsinferno.com Courts, Post-Conte, Decline to Recognize Innovator Liability Theory - Mar 17, 2009 Despite Conte, the Schrock, Cousins and Huck courts each ruled, on summary judgment, that name brand manufacturers of Reglan® (a prescription drug used to Mondaq News Alerts (registration) Land, housing prices bite dust in Panchkula too - Mar 17, 2009 ...is something to suit everybody's pocket in the market. That makes this the right time for buying," said promoter of Reglan Infrastructures Ritu Singhal. Times of India Reglan Issued "Black Box" Warning - Mar 5, 2009 What is Reglan?? Reglan is used for the short-term treatment of heartburn (caused by gastroesophageal reflux) in patients who have already tried other InjuryBoard.com Reglan Side Effects "Frightening" - Mar 3, 2009 Flushing, NY: Shelee H. says she may have been suffering from Reglan side effects for the past year but never realized it. She was prescribed the drug Lawyers and Settlements FDA Requires Boxed Warning for Metoclopramide Products - Mar 11, 2009 Produced in several formulations, metoclopramide is marketed as Reglan and is used by more than 2 million Americans, according to the FDA. AAFP News Now Caloric deficit is key for a diet's success - Mar 10, 2009 In last week's article, "Common drug causes spastic movements," I remarked that the drug Reglan (as well as Phenergan) belonged to the phenothiazine class Great Falls Tribune Gastrointestinal drug gets 'black box' warning - Mar 6, 2009 Also sold as Reglan, Octamide and Maxolon, metoclopramide is used to treat certain gastrointestinal problems. If taken chronically, it can cause a serious Los Angeles Times California Appeals Court Ruling May Lead to Direct Liability for ... - Mar 5, 2009 Conte claimed that Wyeth knew, or should have known, that physicians prescribe Reglan and its generic equivalents for periods exceeding the 12-week period Linex Legal The Mulligan Law Firm Is Now Evaluating Potential Reglan® Injury Cases - Feb 28, 2009 The Mulligan Law Firm announces the addition of Reglan® to their list of prescription drug injury cases they are investigating / evaluating to potentially Emediawire (press release) Amicus halts trial enrollment; FDA wants more Televancin data; - Feb 27, 2009 Report > FDA is slapping a black-box warning on Reglan (metoclopramide) drugs, widely used by patients with chronic heartburn and other gastrointestinal FierceBiotech National Digest - Feb 27, 2009 The Food and Drug Administration said the drug, widely known as Reglan, has been shown to cause spasms and tics when used for long periods of time or at Annapolis Capital Is botulinum toxin injection of the pylorus during Ivor–Lewis ... - Mar 11, 2009 Metoclopramide (Reglan, Baxter Pharmaceutical), erythromycin, and esomeprazol (Nexium, AstraZeneca Pharmaceuticals) were started on the day of the operation The Journal of Thoracic and Cardiovascular Surgery Iowa state senator seeks to legalize medical marijuana - Mar 9, 2009 He’s reluctant to take Reglan, which can cause irreversible Parkinsons-like shakes and tremors, and Marinol is ineffective for him. DesMoinesRegister.com ì†?쓰린ë?° 먹는 약, 블랙박스 ê²½ê³ - Mar 1, 2009 ...â€˜ë ˆê¸€ëž€(Reglan)’ì?´ë?¼ 불리는 ì?´ 약ì?€ 근육발작, ì•ˆë©´ê²½ë ¨ë“±ì?„ ì?¼ìœ¼í‚¤ëŠ” 것으로 나타났다. FDA는 지난 달 28ì?¼ â€œë ˆê¸€ëž€(성분명 metoclopramid)ì?„ 장기복용하거나 헬스코리아뉴스 Liberarán internet, pero hay dudas sobre servicio de VoIP - Mar 7, 2009 ...“La concesión que posee la Copaco para prestar dicho servicio significa el tener derechos, como obligaciones que cumplir, al existir normativas que reglan La Nación (Paraguay) 타는듯한 ì†?쓰림 ì‹?사습관 ê³ ì³?ë?¼ - Mar 9, 2009 ...ìœ„ìž¥ìž¥ì• ì¹˜ë£Œì œë¡œ ì“°ì?´ëŠ” ë©”í† í?´ë¡œí”„ë?¼ë§ˆì?´ë“œ 성분ì?´ 들어 있는 약물로는 브랜드명 ë ˆê¸€ëž€(Reglan), 옥타마ì?´ë“œ(Octamide), ë§¥ì†”ë¡ (Maxolon) 등으로 위 ìš´ë?™ ê°œì„ ì œ 미주 한국일보 Inseguridad y las drogas, los temas ausentes - Mar 1, 2009 ...público debe estar subordinada a las leyes, y resolvà asistir para no incumplir las disposiciones de la Constitución que reglan mi mandatoâ€?, argumentó. La Gaceta Tucumán Neil Barret Womenswear Autumn Winter 2009 - Mar 11, 2009 Soffici maniche reglan tipo cardigan per cappotti dal taglio sartoriale, giacche, abiti e sportswear. Flanelle di jersey, nappa stretch iridescente e con Fashionblog Cal. Court Approves Suit vs. Brand-Name Drug Maker for Injuries ... - 04 Feb 2009 Pharmaceuticals failed to provide adequate warnings about the risks of developing tardive dyskinesia from the generic version of Wyeth’s drug, Reglan. Attorney at Law Wyeth Held Liable in Case Where Patient Never Took the Company’s Drug - Jan 22, 2009 Her doctor prescribed her Wyeth’s Reglan for the disease, but every time she filled her prescription it was switched for a generic, made by Teva, BNET, California Becomes First State to Recognize Innovator Liability - Jan 29, 2009 In Conte, the appellate court held that Wyeth, a name brand manufacturer of Reglan® (a prescription drug used to treat gastroesophageal reflux disease), Mondaq News Alerts (registration), Wyeth decision is Rx for litigation - Jan 28, 2009 The case involves Wyeth's pioneer drug Reglan, which the firm stopped making in 2001. The plaintiff's doctor prescribed Reglan, but the pharmacist filled NewsBlaze (press release), Calif. Supreme Court OKs lawsuit against Wyeth - Jan 23, 2009 The case was brought originally by Elizabeth Conte, who claimed she took the generic version of Wyeth's anti-heartburn drug Reglan for four years to treat Legal News Line, How dangerous is Marijuana? - Jan 18, 2009 This includes 196 deaths caused by taking anti emetics (Compazine, Reglan, Marinol, Zofran, Anzemet, Kytril, Tigan), 118 for taking anti-spasmodics Denver Post, Pregnancy can cause grave illness for some women - Jan 10, 2009 Doctors prescribed anti-nausea medications: first Reglan, and then Compazine suppositories, both of which prevent dopamine, a neurotransmitter, Leader-Telegram, Abogados reglan nuevo Jus - Jan 13, 2009 A pedido de este Colegio de Abogados de la Primera Circunscripción Judicial, por Acordada Ordinaria N° 42/08 punto Noveno, el STJ fijó el Jus en $ 101,87 Momarandu.com, Reglan el blanqueo de personal - Jan 22, 2009 El ministerio de Trabajo reglamentó los artÃculos de la ley de la moratoria fiscal que establecen beneficios a las empresas que regularicen hasta 10 Noticias de Quilmes, Las letras sacuden Cartagena - Jan 28, 2009 Vila matas, o Amis y que aún asà le reglan grandiosas charlas a Cartagenaâ€?, comenta por su parte, el escritor colombiano Antonio GarcÃa. El Espectador (Colombia), Santa Fe se sumará a la Agencia Nacional de Seguridad Vial - Jan 18, 2009 Se refiere a iniciativas presentadas en la Legislatura, a la normativa vigente asà como al sinnúmero de ordenanzas que reglan la cuestión en cada lugar del ElLitoral.com, ¿Prescribió o no prescribió? - Dec 16, 2008 ...“...el ámbito de aplicación de las normas que reglan el instituto de la prescripción a supuestos no contemplados en el ordenamiento jurÃdicoâ€?. Diario Judicial, Brand Names/Synonyms: Reglan is also known by the following brand names and/or synonymsApo-Metoclop; CHEMBANK734; Cerucal; Clopra; Clopra-Yellow; Clopromate; DEL; DEL 1267; DEL-1267; Duraclamid; Elieten; Emetid; Emperal; Eucil; Gastrese; Gastro-Timelets; Gastrobid; Gastromax; Gastronerton; Gastrosil; Gastrotablinen; Gastrotem; Imperan; M0763; M117; Maxeran; Maxolon; Meclopran; Metaclopramide; Metaclopromide; Metamide; Methochlopramide; Methoclopramide; Metochlopramide; Metoclol; Metoclopramida [Inn-Spanish]; Metoclopramide; Metoclopramide Hcl; Metoclopramide Hydrochloride; Metoclopramide Intensol; Metoclopramide Omega; Metoclopramidum [Inn-Latin]; Metocobil; Metramid; Moriperan; Mygdalon; Neu-Sensamide; Nu-Metoclopramide; Octamide; Parmid; Paspertin; Peraprin; Plasil; Pms-Metoclopramide; Pramiel; Pramin; Primperan; Reclomide; Reglan; Reliveran; Terperan Drug Category: Reglan is categorized under the following by the FDA: Antiemetics; Prokinetic Agents; Dopamine Antagonists; ATC:A03FA01 Dosage Forms: LIQUID; SYRUP; TABLET Absorption: Rapidly and well absorbed (oral bioavailability 80±15.5%). Interactions: DRUG INTERACTIONS The effects of metoclopramide on gastrointestinal motility are antagonized by anticholinergic drugs and narcotic analgesics. Additive sedative effects can occur when metoclopramide is given with alcohol, sedatives, hypnotics, narcotics, or tranquilizers. The finding that metoclopramide releases catecholamines in patients with essential hypertension suggests that it should be used cautiously, if at all, in patients receiving monoamine oxi-dase inhibitors. Absorption of drugs from the stomach may be diminished (e.g., digoxin) by metoclopramide, whereas the rate and/or extent of absorption of drugs from the small bowel may be increased (e.g., acetaminophen, tetracycline, levodopa, ethanol, cyclosporine). Gastroparesis (gastric stasis) may be responsible for poor diabetic control in some patients. Exogenously administered insulin may begin to act before food has left the stomach and lead to hypoglycemia. Because the action of metoclopramide will influence the delivery of food to the intestines and thus the rate of absorption, insulin dosage or timing of dosage may require adjustment. Chemical IUPAC Name: 4-amino-5-chloro-N-(2-diethylaminoethyl)-2-methoxy-benzamide : |
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