Proventil

This page contains recent news articles, when available, and an overview of Proventil but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Proventil
(when available)

Pharmacology and use:
Vincristine is a vinca alkaloid antineoplastic agent used as a treatment for various cancers including breast cancer, Hodgkin's disease, Kaposi's sarcoma, and testicular cancer. The vinca alkaloids are structurally similar compounds comprised of 2 multiringed units, vindoline and catharanthine. The vinca alkaloids have become clinically useful since the discovery of their antitumour properties in 1959. Initially, extracts of the periwinkle plant (Catharanthus roseus) were investigated because of putative hypoglycemic properties, but were noted to cause marrow suppression in rats and antileukemic effects in vitro. Vincristine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death. Vincristine has some immunosuppressant effect. The vinca alkaloids are considered to be cell cycle phase-specific. For treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, acute panmyelosis

Mechanism Of Action:
The antitumor activity of Vincristine is thought to be due primarily to inhibition of mitosis at metaphase through its interaction with tubulin. Like other vinca alkaloids, Vincristine may also interfere with: 1) amino acid, cyclic AMP, and glutathione metabolism, 2) calmodulin-dependent Ca2+-transport ATPase activity, 3) cellular respiration, and 4) nucleic acid and lipid biosynthesis.

News Articles on Vincristine

US runners show physical toll of world championship marathon  -  ‎Aug 23, 2009‎
..."I think I'm going to pass out," Moody told medical staff around her as they rushed to get her emergency Proventil inhaler while trying to calm her down. Los Angeles Times

BUY CHEAP PROVENTIL ONLINE  -  ‎Jul 12, 2009‎
12, 2009 at 3:03 PM Proventil is a bronchodilator that relaxes muscles in the airways and increases air flow to the lungs. Proventil is used to treat or Cleveland Indy Media

NEWS | SAN DIEGO Something to Share With You  -  ‎Jun 22, 2009‎
At 9:38 pm the respiratory therapist gave a breathing treatment of Proventil via a mask. The patient's heart rate was elevated up to the 120's before and San Diego Daily Transcript (subscription)

Link Could Exist Between Arthritis Drug, Pediatric Cancer  -  ‎Apr 14, 2009‎
Three HFA-propelled albuterol inhalers have been approved by the FDA: Proair HFA Inhalation Aerosol, Proventil HFA Inhalation Aerosol and Ventolin HFA ADVANCE for LPNs

Statins good for asthma too  -  ‎Mar 15, 2009‎
...but more severe cases may also require short-acting beta-agonists or rescue medicines, such as Albuterol and Proventil; long-acting beta-agonists, Los Angeles Times

Asthma inhalers: Which one's for you?  -  ‎Mar 2, 2009‎
These medications, including albuterol (Proventil, Ventolin) and pirbuterol (Maxair), provide immediate relief of asthma symptoms. WTHI

Doctors Hear Gripes About HFA Inhalers  -  ‎Mar 11, 2009‎
ProAir has ethanol and Proventil has ethanol and oleic acid. Xopenex has dehydrated alcohol and oleic acid. Sander says many of the complaints her MedPage Today

Schering-Plough Q4 2008 Earnings Call Transcript  -  Feb 3, 2009
We also saw higher sales of REMICADE, NASONEX, PROVENTIL and TEMODAR. Offsetting this growth, were sales declines for CLARINEX, AVELOX and PEGINTRON. Seeking Alpha,

New inhalers cause problems for some asthma sufferers  -  Jan 19, 2009
Williams’ doctor Todd Freudenberger put her on Proventil. Although the new inhalers work as well or better than the old CFC delivery systems, Sammamish Review,

New Rules for Inhalers Start With New Year  -  Dec 11, 2008
To date, the FDA has approved three HFA-propelled albuterol inhalers: Proair HFA Inhalation Aerosol, Proventil HFA Inhalation Aerosol and Ventolin HFA AAFP News Now

Are You Taking the Right Asthma Medication?  -  Dec 9, 2008
The most commonly used rescue inhaler is known as Proventil (albuterol), which relaxes the muscles around the airways in the lungs. FOXNews

How to use new asthma inhalers  -  Dec 13, 2008
HFA inhaler manufacturers: Proventil: Schering Plough, proventilhfa.com, 877-HFA-7768. Ventolin: GlaxoSmithKline, ventolin.com, 888-825-5249. Sun-Sentinel.com,

Breathe easy? Green inhalers are good for the environment, but are ...  -  Dec 4, 2008
There are three green albuterol inhalers: GlaxoSmithKline's Ventolin HFA, Schering Plough's Proventil HFA and Teva Specialty Pharmaceuticals' ProAir HFA. Scientific American

New 'Green' Inhalers May Be Confusing, Pricey  -  Dec 17, 2008
The CFC-free options: GlaxoSmithKline's Ventolin HFA, Schering Plough's Proventil HFA and Teva Specialty Pharmaceuticals' ProAir HFA all contain albuterol. FOXNews

Schering-Plough Touts Pipeline Over Competitors'  -  Dec 1, 2008
Despite all the news about promising future products and its much-improved finances, the maker of hepatitis drugs, the Proventil and Asmanex asthma inhalers Pharmaceutical Processing,

ACAAI: Newer Albuterol Inhalers Not Created Equal  -  Nov 10, 2008
Explain to interested patients that the Proventil brand of HFA-driven albuterol inhalers may be more prone to clogging than other brands if not washed MedPage Today,

The inhaler squeeze  -  Nov 21, 2008
...which began producing the environmentally friendly Ventolin HFA in 2002, and Schering-Plough, which introduced its Proventil HFA in 1996, didn't compete Rocky Mountain News,

Latest research on diagnosis and treatment of allergic diseases  -  Nov 11, 2008
This study evaluates the risk for clogging if ProAir, Proventil, and Ventolin are not cleaned through the life of the device. All three products did not News-Medical.net,

Changes coming for inhaler users  -  Nov 11, 2008
A Proventil inhaler has been around for about a year now, and has proven to be just as effective as the old inhalers. The one difference - you have to prime 7Online.com,

CHEST: Arformoterol Passes Six-Month Safety Test in COPD  -  Oct 30, 2008
At six months, patients had reduced use of ipratropium bromide (Atrovent) and levalbuterol (Xopenex) or albuterol (ProAir, Proventil) by means of 0.9 to 1.3 MedPage Today,

Schering-Plough Reports Financial Results for Third Quarter of 2008  -  21 Oct 2008
ELOCON 45 40 12% 137 119 15% ASMANEX 40 36 12% 131 121 9% NOXAFIL 40 24 62% 111 60 85% PROVENTIL / ALBUTEROL CFC 38 52 (26%) 127 166 (23%) MERCILON c/ PR Newswire (press release),

Test your lungs – know your numbers  -  Oct 19, 2008
Medications, called bronchodilators and commonly known as Albuterol, Proventil and Xopenex are aimed at decreasing airway swelling and wheezing. Wilmington News Journal, OH,

New asthma inhalers out of reach for some  -  Oct 4, 2008
We are being offered Pro Air HPA, Xopenex HPA and Proventil HPA, and the cheapest that I was able to find one of these in Abilene was for around $25. Abilene Reporter-News,

'Greener' asthma inhalers have issues of their own  -  Oct 8, 2008
Renold said better results have been had with Ventolin HFA, which has a dosage counter, and with Proventil HFA. He said there have been some difficulties The Courier News,

Environmental concerns force asthma inhaler off the market  -  Sep 26, 2008
The old Albuterol inhalers, which use are the generic forms of Ventolin and Proventil inhalers, will no longer be available after Dec. 31. Abilene Reporter-News,

Senior Dimensions Lowers Prescription Drug Co-Payments on Many ...  -  Sep 24, 2008
...both used to treat hypertension; Actos and Lantus, used to treat diabetes; Symbicort, used to treat COPD; and Proventil HFA, for COPD and asthma. RedOrbit,

New asthma inhalers better for environment, but not for pocketbook  -  Aug 24, 2008
Like the CFC inhalers, the HFA inhalers sold under the brand names ProAir, Ventolinand Proventil contain albuterol, a medicine that relaxes the muscles that Barre Montpelier Times Argus,

Finding the right asthma inhaler  -  Aug 8, 2008
Proventil, Pro Air, and Xopenex do use ethanol as an excipient. If you are experiencing more difficulty than usual breathing with your new inhaler, Rutland Herald,

A new asthma inhaler that's better for environment  -  Aug 6, 2008
Like the CFC inhalers, the HFA inhalers sold under the brand names ProAir, Ventolinand Proventil contain albuterol, a medicine that relaxes the muscles that Rutland Herald,

Working out a Diagnosis  -  Jul 28, 2008
A short-acting inhaled medicine such as albuterol (Proventil, Ventolin, ProAir) or pirbuterol (Maxair), used 15 minutes before exercise to prevent symptoms Dubuque Telegraph Herald,

Swimmer Jessica Hardy's Competitors Are Permitted to Use Similar ...  -  Jul 25, 2008
Some examples of LABAs approved by WADA for therapeutic purposes include Advair Diskus, Advair HFA, Brovana, Foradil, Perforomist, Proventil, Bleacher Report,

Schering-Plough Reports Financial Results for Second Quarter of 2008  -  Jul 21, 2008
77 - - PROVENTIL / ALBUTEROL CFC 38 61 (37%) 89 114 (22%) NOXAFIL 38 20 91% 72 36 101% FORADIL 25 26 (1%) 51 52 (2%) Other Pharmaceuticals 755 438 72% PR Newswire (press release),

CFC-propelled inhalers to be discontinued  -  02 Jun 2008
Three HFA-propelled albuterol inhalers have been approved by the FDA: Teva's Proair HFA, Schering-Plough's Proventil HFA, and GlaxoSmithKline's Ventolin HFA Prescribing Reference,

Health Buzz: Kennedy's Brain Surgery, Asthma Inhalers, and Other ...  -  02 Jun 2008
Three such inhalers are available: ProAir HFA Inhalation Aerosol, Proventil HFA Inhalation Aerosol, and Ventolin HFA Inhalation Aerosol. U.S. News & World Report,

Embracing Change In Asthma Treatments  -  02 Jun 2008
...“The good news is there are four ozone-safe products on the market: Proventil® HFA, ProAir® HFA, Ventolin® HFA and Xopenex HFA®. Xopenex HFA is different North American Press Syndicate,

FDA: Patients Should Switch to HFA Inhalers  -  02 Jun 2008
The albuterol HFA inhalers approved by the FDA include Teva Pharmaceutical Pharmaceutical Industries Ltd's ProAir HFA, Schering-Plough Corp's Proventil HFA eFluxMedia

FDA Advises Patients to Switch to HFA-Propelled Albuterol Inhalers Now  -  02 Jun 2008
Three HFA-propelled albuterol inhalers have been approved by the FDA: Proair HFA Inhalation Aerosol, Proventil HFA Inhalation Aerosol, and Ventolin HFA Media Newswire (press release),

FDA: Time for asthma patients to switch inhalers  -  May 30, 2008
CFC-free albuterol inhaler options include GlaxoSmithKline's Ventolin HFA, Schering Plough's Proventil HFA and Teva Specialty Pharmaceuticals' ProAir HFA. The Associated Press

New Environment-Friendly Asthma Inhalers To Replace The Current ...  -  May 31, 2008
...by drug companies like GlaxoSmithKline's Ventolin HFA. Other options include Schering Plough's Proventil HFA and Teva Specialty Pharmaceuticals' ProAir HFA. AHN

Allergy sufferers: your inhaler is about to change, get more expensive  -  May 20, 2008
The new HFA albuterol inhalers include ProAir by Teva, Proventil by Schering-Plough and Ventolin by GlaxoSmithKline. Manufacturers of the new inhalers also KARE,

Ozone-Depleting Inhalers Being Phased Out  -  May 30, 2008
Three HFA-propelled albuterol inhalers have been approved by the FDA: Proair HFA Inhalation Aerosol; Proventil HFA Inhalation Aerosol; and Ventolin HFA Washington Post,

Rough Transition to a New Asthma Inhaler  -  May 14, 2008
The four HFA inhalers are Ventolin by GlaxoSmithKline, ProAir by Teva, Proventil by Schering-Plough and Xopenex by Sepracor. (Xopenex uses a different New York Times,

US alerts asthma patients about inhaler switch  -  May 30, 2008
Schering-Plough Corp (nyse: SGP - news - people )'s Proventil HFA and GlaxoSmithKline (nyse: GSK - news - people ) Plc's Ventolin HFA. Forbes,

FDA: Time for asthma patients to switch inhalers  -  May 30, 2008
CFC-free albuterol inhaler options include GlaxoSmithKline‘s Ventolin HFA, Schering Plough‘s Proventil HFA and Teva Specialty Pharmaceuticals‘ ProAir HFA. Prescott Herald,

Asthmatics Should Switch Over To Hydrofluroalkane Inhalers  -  May 30, 2008
According to FDA, CFC-free albuterol inhaler options include GlaxoSmithKline's Ventolin HFA, Schering Plough's Proventil HFA and Teva Specialty TopNews,

Asthma inhalers are changing  -  Feb 12, 2008
About your concern: Proventil HFA and ProAir HFA contain ethanol in small amounts, but Ventolin HFA is ethanol-free. The latter product, then, Kentucky.com,

ViroPharma enters new era  -  Feb 28, 2008
...in cold and allergy remedy medicines, with such labels as Coricidin, Nasonex, Claritin and Proventil in its armory — for development as a nasal spray. Chester DailyLocal.com,

Asthma inhalers to change in December  -  Jan 30, 2008
The newer HFA-based albuterol inhalers include Proventil HFA, ProAir HFA, and Ventolin HFA. To speak to your worry: Though Proventil HFA and ProAir HFA Biloxi Sun Herald,

Six Stocks to Keep You, and Your Portfolio Healthy  -  Dec 18, 2007
Clarinex for allergic rhinitis, Foradil and Asmanex for asthma, Proventil for bronchospasm, Avelox for respiratory and skin infections. Seeking Alpha,

Asthma - pediatric  -  Nov 2, 2007
These include: Short-acting bronchodilators (inhalers), such as Proventil, Ventolin, Xopenex, and others. Although these are the same medications used to New York Times,

Don't stop asthma meds while pregnant  -  Nov 6, 2007
Quick-relief inhaled medicines like albuterol (Ventolin, Proventil) are considered safe. The inhaled long-acting bronchodilators such as salmeterol Times Daily (subscription),

Schering-Plough Reports Financial Results for Third Quarter of 2007  -  Oct 22, 2007
61 57 7% 176 180 (2%) REBETOL 60 72 (16%) 206 237 (13%) SUBUTEX / SUBOXONE 55 51 8% 163 152 7% PROVENTIL / ALBUTEROL CFC 52 45 16% 166 148 12% ELOCON 40 PR Newswire (press release),

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MORE BOMB THAN BALM  -  Oct 2, 2007
...blood-thinning warfarin, again increasing the risks of bleeding and bruising. nausea prescription drug phenergan, or proventil, an asthma medication. New York Post,

Environmental concerns fuel transition from CFC to HFA asthma inhalers  -  Oct 1, 2007
Pediatricians increasingly have been asked by pharmacies to select one of the four available HFA substitutes/brands (ProAir, Ventolin HFA, Proventil HFA and AAP News (subscription)

FDA phases out CFCs in asthma inhalers  -  Sep 28, 2007
Several popular inhalers, including Xoponex, Proventil and Flovent, which use albuterol and rely on CFCs to propel the drug, will no longer be on shelves Gary Post Tribune,

FDA Expands Ban on Ozone-Depleting Substances  -  Sep 25, 2007
In addition, the FDA highlighted 3M’s success in reformulating Proventil (albuterol) as an ozone-safe formulation. The FDA proposed banning the use of ODSs FDA news (subscription),

Phasing out generic, CFC-powered asthma inhalers  -  Sep 3, 2007
Brand names such as ProAir HFA, Proventil HFA and Ventolin HFA all contain albuterol, but they do cost more than the old, generic CFC-powered inhalers. Los Angeles Times,

Asthma medicines sometimes spurned  -  Sep 5, 2007
They are being replaced by an alternative propellant called fluoroalkane, known as HFA, under brand names such as ProAir HFA, Proventil HFA and Ventolin HFA Rochester Democrat and Chronicle,

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Schering-Plough Reports Financial Results for Second Quarter of 2007  -  Jul 23, 2007
PR Newswire (press release),74 86 (14%) 146 164 (11%) CAELYX 65 53 23% 127 104 22% PROVENTIL/ALBUTEROL CFC 61 63 (4%) 114 104 10% INTRON A 55 64 (13%) 115 124 (7%) SUBUTEX/SUBOXONE

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Brand Names/Synonyms:
Proventil is also known by the following brand names and/or synonymsIndole alkaloid; LCR; Leurocristine; Onco TCS; Oncovin; VCR; VIN; Vincasar PFS; Vincrex; Vincristina [DCIT]; Vincristine; Vincristine Sulfate; Vincristine Sulfate PFS; Vincristinum [INN-Latin]; Vincrstine; Vincrystine; Vinkristin; 22-Oxovincaleukoblastine; EINECS 200-318-1; Oncovin (1:1 sulfate salt); Vincaleukoblastine, 22-oxo-; Vincasar (1:1 sulfate salt); Vincrex (1:1 sulfate salt); Z-D-Val-Lys(Z)-OH

Drug Category:
Proventil is categorized under the following by the FDA: Antineoplastic Agents; ATC:L01CA02

Dosage Forms:
LIQUID; SOLUTION

Absorption:
Not Available

Interactions:
Interactions for Vincristine: The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. Dosage adjustment should be based on serial blood level monitoring. The contribution of vincristine sulfate to this interaction is not certain. The interaction may result from reduced absorption of phenytoin and an increase in the rate of its metabolism and elimination.



Chemical IUPAC Name:
Not Available

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