Proscar

This page contains recent news articles, when available, and an overview of Proscar but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Proscar
(when available)

Pharmacology and use:
Finasteride is indicated for the treatment of male pattern hair loss (androgenetic alopecia) in men only. Finasteride is a competitive and specific inhibitor of Type II 5a-reductase, an intracellular enzyme that converts the androgen testosterone into DHT. Two distinct isozymes are found in mice, rats, monkeys, and humans: Type I and II. Each of these isozymes is differentially expressed in tissues and developmental stages. In humans, Type I 5a-reductase is predominant in the sebaceous glands of most regions of skin, including scalp, and liver. Type I 5a-reductase is responsible for approximately one-third of circulating DHT. The Type II 5a-reductase isozyme is primarily found in prostate, seminal vesicles, epididymides, and hair follicles as well as liver, and is responsible for two-thirds of circulating DHT. For the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate to: Improve symptoms, reduce the risk of acute urinary retention, reduce the risk of the need for surgery including transurethral resection of the prostat

Mechanism Of Action:
The mechanism of action of Finasteride is based on its preferential inhibition of Type II 5a-reductase, an intracellular enzyme that converts the androgen testosterone into DHT. Inhibition of Type II 5a-reductase blocks the peripheral conversion of testosterone to DHT, resulting in significant decreases in serum and tissue DHT concentrations.

News Articles on Finasteride

Drink Less: Heavy alcohol use may increase risk of prostate cancer  -  ‎Aug 25, 2009‎
Also, among men who had been randomly assigned to take finasteride (Proscar, Propecia) as part of other research to test the drug's ability to prevent Winston-Salem Journal

(Maryland) OhNine OnLine for August 3--Mayoral Forum to Focus on ...  -  ‎Aug 3, 2009‎
...[b]Proscar (Finasteride) is an androgen hormone inhibitor used in men to treat Benign Prostatic Hyperplasia (BPH) which is swelling of the prostate. Politicker

Dr. Oz talks about saw palmetto for enlarged prostate, or BPH  -  ‎Aug 11, 2009‎
In recent studies, saw palmetto had a similar effectiveness as finasteride (Proscar®), the drug most commonly prescribed in the US Though it can take 4 to 6 Examiner.com

Beth Israel Deaconess Medical Center Correspondent  -  ‎Aug 20, 2009‎
Newer drugs such as Avodart or Proscar, in the category known as 5a-reductase inhibitors, actually work to shrink the prostate itself. Boston Channel.com

Hair today can be gone tomorrow  -  ‎Aug 17, 2009‎
There are only two FDA approved products that have been clinically proven to stop or prevent hair loss, according to the AHLA: Finasteride (Proscar and Frederick News Post (subscription)

Congress Mulling Ban on Drug Ads  -  ‎Aug 11, 2009‎
FDA regulators, reported the Star Tribune, said the claim is bogus and in a letter to Glaxo's US officials, wrote that Merck's Proscar reduces prostate size Newsinferno.com

Treatment for prostate debated  -  ‎Aug 7, 2009‎
Dear Dr. Donohue — I just learned of a new feature of finasteride (Proscar). It is likely that it is a deterrent for prostate cancer. St. Louis Post-Dispatch

Drinking Moderately or More Ups Men's Cancer Risk  -  ‎Aug 7, 2009‎
...developing aggressive prostate cancer in men while undermining the effectiveness of the popular prostate cancer prevention drug finasteride (Proscar). Atlanta Journal Constitution

Uống rượu nhiá»?u có nguy cÆ¡ bị ung thư nhiếp há»™ tuyến cao  -  14 Jul 2009
Nghiên cứu còn cho thấy dược chất finastoride được bán ngoài thị trưá»?ng dưới tên như Proscar, Propecia, Fincar, Finpecia, Finax, Finast, Finara, Finalo, Người Việt

Heavy Drinking Linked to Aggressive Prostate Cancer  -  ‎Jul 13, 2009‎
...on prostate cancer risk but rather to test the effectiveness of finasteride (Proscar, Propecia), a drug prescribed to prevent prostate cancer. Forbes

Propecia Proscar Avodart Cheapen Prices  -  ‎Jun 27, 2009‎
...expression Federation Federation Pharmaceuticalof preferenceto Dotted the and Dotted nature Propecia Proscar Avodart Cheapen Prices use World excepted, Västerbottens Folkblad

The Drug Finasteride Proscar Propecia Hair Loss  -  ‎Jun 27, 2009‎
Or whatsoever agreement.endorsed International The Drug Finasteride Proscar Propecia Hair Loss boundaries. lines not of any not yet Organization initial of Västerbottens Folkblad

Actavis Launches Finasteride As Patent Expires In France  -  ‎Jun 24, 2009‎
Finasteride, used for the treatment of prostate cancer, is the generic equivalent of Merck's Proscar. Finasteride Actavis is available in tablets of 5mg in Pharmaceutical Business Review

New Report Just Published: World Prostate Cancer Therapeutics ...  -  ‎Jul 7, 2009‎
...to Introduce IGRT II-66 Immunomedics Introduces Immunotoxin for Treatment of Prostate and Lung Cancer II-66 Barr Unveils Generic Version of Proscar(R) PR Newswire (press release)

Prostate Shrinkage May Reveal High-Grade Cancer  -  ‎Jul 7, 2009‎
...in a detection bias in the finasteride (Proscar/Propecia) arm of the Prostate Cancer Prevention Trial (PCPT), data from a large patient series suggest. MedPage Today

BUYINS.NET: MRK, CMN, SYNO, SUI, COMS. Top Losing Stocks With ...  -  ‎Jul 9, 2009‎
Proscar to treat symptomatic benign prostate enlargement; and Emend for the prevention of chemotherapy-induced and post-operative nausea and vomiting. Trading Markets (press release)

Medicinal chemist honored nationally  -  ‎Jun 28, 2009‎
...high blood pressure; the antibiotic Primaxin; cholesterol-lowering Mevacor; Proscar for enlarged prostates; and Ivomec, used to combat river blindness. Philadelphia Inquirer

WhisperfromWallStreet.com Afternoon Shakers - MRK - Merck  -  ‎Jul 9, 2009‎
Proscar to treat symptomatic benign prostate enlargement; and Emend for the prevention of chemotherapy-induced and post-operative nausea and vomiting. TransWorldNews (press release)

Medtronic subpoenaed on accused doc; FDA eyes Depakote effects on ...  -  ‎Jun 24, 2009‎
Report > Actavis launched the generic prostate cancer treatment Finasteride in France Monday, the day Merck's patent on the branded version Proscar expired. FiercePharma

Ralph Hirschmann Dies At 87  -  ‎Jun 23, 2009‎
They include Vasotec, Lisinopril, Primaxin, Mevacor, Proscar, and Ivomec. In 1987, after his mandatory retirement from Merck at age 65, Hirschmann joined Chemical & Engineering News

Generic finasteride  -  ‎Jul 2, 2009‎
Finasteride belongs to the volume discount proscar hypersensitivity to any contact with finasteride. Pharmacy costs, generic finasteride were analyzed. Tiscali.cz

Prostate, Brain & Kidney Cancers  -  ‎Jun 18, 2009‎
In 2003, another 5-alpha reductase inhibitor called Proscar (finasteride) was shown to lower the risk of prostate cancer after seven years, but in men with Curetoday.com (press release)

Red je haar (4 - slot)  -  ‎Jun 24, 2009‎
In dat geval heet het medicijn geen Propecia maar Proscar en is de dosering niet 1 maar 5 mg finasteride. Miljoenen vijftigplussers slikken al minstens Gaysite.nl

El fármaco «reciclado» sanea el balance de sus fabricantes  -  ‎Jun 25, 2009‎
Este medicamento, formulado para tratar la alopecia androgenética (la predominante en el varón) es un 'remake' de Proscar, diseñado para tratar la elmundo.es

GAZZETTA UFFICIALE: SOMMARIO (2)  -  ‎Jun 19, 2009‎
Autorizzazione all'immissione in commercio del medicinale per uso umano "Proscar". Autorizzazione all'immissione in commercio del medicinale per uso umano ANSA Valle d'Aosta

Merck Generics offers generic propecia  -  20 Apr 2009
Proscar the generic propecia has everything for your hairs. Generic propecia provides energy needs of your hairs. Most of hair problems, especially male Merinews

Phì đại nhiếp tuyến  -  20 Apr 2009
Có nhiá»?u dược phẩm làm nhiếp tuyến teo (Proscar) hoặc làm thư giãn cÆ¡ thịt ở vùng xương chậu (Hytrin), khiến tiểu tiện được thông. Thời Báo Online

Propecia: Genuine solution to hail loss problem  -  ‎Apr 18, 2009‎
Now, try propecia proscar to enable your hair to enjoy the best of health. Proscar is made in beautiful packing in one mg tablet form that you can use it Merinews

Changes Made In Blood Donation Criteria  -  ‎Apr 10, 2009‎
Some exclusions still remain in effect. Donors taking Proscar, Avodart, Propecia, Accutane, Soriatane, Tegison, growth hormones, The Chattanoogan

For Men Only  -  ‎Apr 2, 2009‎
Saw palmetto, the drugs Proscar and Flomax all appear to work by a similar mechanism, inhibition of DHT production but saw palmetto also inhibits binding of Ada Evening News

Best drug for your hair: Propecia  -  ‎Apr 5, 2009‎
No sooner than in 97s FDA , USA clinically tested propecia or proscar and accepted it as sole caretaker of male pattern hair loss problem. Merinews

Reduce hair loss with Propecia  -  ‎Apr 7, 2009‎
Propecia, generally renowned as proscar has visible results according to an independent panel of dermatologists, whic assessed photographs after the use of Merinews

Aurobindo Pharma secures first nod for Finasteride APL Tablets  -  ‎Apr 8, 2009‎
The drug is generic equivalent of MERCK & CO., Inc's Proscar Tablet. Finasteride APL Tablet 5mg is used alone or in combination with another medication to TopNews

"'아보다트' 전립선암 예방 ì ?ì?‘ì¦? 기대"  -  ‎Apr 14, 2009‎
...ì?´ëŸ° í?¬ë§?ì—?ë?„ 불구하고 지난 2003ë…„ 실시ë?œ 유사한 ìž„ìƒ?시험ì—?서는 머í?¬ì?˜ ‘프로스카(Proscar)'ê°€ 전립선암 위험성ì?€ 낮췄지만 진행성 종양ì?˜ 위험ì?€ 높ì?´ëŠ” 것으로 데일리팜

Tabela reajustada de remédios vai chegar nas farmácias na próxima ...  -  ‎Apr 10, 2009‎
Entre eles, estão medicamentos como: Proscar (tratamento de próstata), Adalat (hipertensão) e os antibióticos Benzetacil, Cefamox e Daktarin. SRZD

DẦU DỪA CHá»®A Ä?Ủ THỨ BỆNH  -  ‎Apr 14, 2009‎
Lúc đ�c trên mạng biết biến chứng của thuốc là khó thở, tôi đổi thuốc, uống Saw Palmetto extract (dược thảo), vì có công dụng như thuốc tây (Proscar). Take2Tango

è€?年病用è?¯éœ€æ±‚é‡?ä¸?断增长å‰?列腺用è?¯â€œå¢žç”Ÿâ€?  -  ‎Apr 2, 2009‎
...é?žé‚£é›„胺(finasteride,商å“?å??Proscar)é?žé‚£é›„胺由美国默沙东公å?¸å¼€å?‘,1992年率先在英国上市,1994年获得批准进å?£ï¼Œå•†å“?å??为“ä¿?列治â€?,在国内主è¦?ç”±æ?­å·žé»˜æ²™ä¸œå…¬å?¸åˆ† 搜狐

Existen medicamentos que podrían prevenir el cáncer de próstata  -  ‎Mar 29, 2009‎
El estudio se ha realizado con un medicamento denominado Proscar, cuyo principio activo Finasteride, también se utiliza, a mitad de dosis, para la caída del Vivir Mejor

Remédios aumentam até 5,91% a partir de terça-feira no Rio  -  ‎Apr 11, 2009‎
Dentre eles, estão medicamentos para tratamento da próstata, como o Proscar; de hipertensão, como o Adalat; e antibióticos, como Benzetacil, Terra Brasil

Remédios mais caros na terça-feira  -  ‎Apr 9, 2009‎
Entre eles, estão Proscar (tratamento de próstata), Adalat (hipertensão) e os antibióticos Benzetacil, Cefamox e Daktarin. Outros 17 da lista pesquisada O Dia Online

Propecia Proscar-One Name That Can Regrow Hair  -  ‎Mar 16, 2009‎
Resultantly, world wide pharmaceuticals retained the authority to produce proscar or generic propecia and serve humanity. Now you can order propecia to buy NewDesignWorld (press release)

Propecia Proscar: The best hair protection  -  ‎Mar 9, 2009‎
It is also significant, in order to completely enjoy the benefits of proscar, a specific time should be given to the consumption of drug. Merinews

Drug May Help Prevent Prostate Cancer  -  ‎Feb 24, 2009‎
24, 2009 -- Millions of healthy men may benefit from talking to their doctors about taking the drug Proscar to prevent prostate cancer, according to new WebMD

FDA Says Glaxo Prostate Drug Ad Misleads  -  ‎Feb 27, 2009‎
The agency pointed out that Merck's(MRK Quote - Cramer on MRK - Stock Picks) Proscar, another drug approved to treat symptoms of benign prostatic TheStreet.com

Risk may offset reward in prostate cancer pill  -  ‎Mar 6, 2009‎
There is a drug called finasteride (known by the brand names of Proscar and Propecia) that works somewhat for all of these issues. Globe and Mail

Propecia prescription one drug for all requirements of hair  -  ‎Mar 4, 2009‎
Proscar or generic propecia is available now to give you a thousand hairs at a spot of your hair. Propecia prescription is applicable to all kinds of your BigNews.biz (press release)

NATION IN BRIEF: Solis confirmed for Labor  -  ‎Feb 25, 2009‎
The advice stops short of saying men should take the drug finasteride, sold in generic form and as Proscar. It has not been widely prescribed as a cancer Atlanta Journal Constitution

Propecia: A drug to control male pattern hair loss  -  ‎Mar 13, 2009‎
The dullness, which has been acquired by your hairs, due to DHT enzyme can be treated in a certain time period with help of propecia proscar. Merinews

GSK ads for Avodart are misleading, says FDA  -  ‎Mar 3, 2009‎
...consumer safety officer, said in the letter, citing Merck's Proscar, another drug approved for the treatment of symptomatic benign prostatic hyperplasia Medical Marketing and Media

Briefs: raising a glass of cheer raises cancer risk among women  -  ‎Feb 25, 2009‎
Finasteride, sold in generic form and as Proscar, can cut the odds of being diagnosed with prostate cancer by about 25 percent, according to reports by Tampabay.com

HealthWatch: Drug May Help Prevent Prostate Cancer  -  ‎Mar 13, 2009‎
That major stride lies in a little blue pill, an inexpensive generic drug called finasteride – brand name Proscar. Finasteride has been used for years to WCBS-TV New York

Health checkup: Prostate cancer  -  ‎Mar 11, 2009‎
Finasteride is marketed under the name Proscar or Propecia; it is a testosterone inhibitor and was initially used to reduce urologic symptoms related to an Rochester Democrat and Chronicle

Sandoz to pay $78.4M in Medicaid case; Dr Reddy's winding down non ...  -  ‎Feb 25, 2009‎
...healthy men who are regularly screened for prostate cancer to consider taking Merck's Proscar or its generic form finasteride to prevent the disease. FiercePharma

Trials of Synta's melanoma drug suspended and stock sinks  -  ‎Mar 2, 2009‎
However, Merck & Co's Proscar (finasteride), which is also available generically, does reduces prostate size, the FDA said. The agency added that it is� not Pharma Times

Valium/Diazepam online pharmacies. Buy valium onli  -  ‎Feb 21, 2009‎
Tadalafil and proscar is Yes we do! The pain nausea or diagnosis. Sleep last these Jason Sweat on 16 no prescription. Buy wellbutrin online or register. Divadlo.cz

La Finasteride non sembra essere associata al rischio di frattura ...  -  ‎Mar 16, 2009‎
Finasteride [ Proscar ] ) per ipertrofia prostatica benigna e fratture dell’anca. Lo studio caso-controllo è stato realizzato utilizzando i dati provenienti XagenaSalute

Medicamento contra cáncer de próstata luce prometedor  -  ‎Feb 24, 2009‎
La nueva directriz no llega a ser una recomendación directa para tomar el fármaco finasterida, que se conoce comercialmente como Proscar, porque tiene sus Univisión

治禿柔沛新療效兼防æ”?護腺癌  -  ‎Feb 26, 2009‎
...低劑é‡?抗禿頭高劑é‡?æ‰?能抗癌低劑é‡?柔沛目å‰?被用為抗禿頭藥,高劑é‡?柔沛上市藥å??為「波斯å?¡ã€?(Proscar),孕峖b治療æ”?護腺腫大,都是美國默克藥廠所生產。 中天新聞

é ?測å‰?列腺癌風險的新方法  -  ‎Mar 2, 2009‎
Roobolå?šå£«è¡¨ç¤ºï¼Œå¦‚果未來的風險很高,你å?¯èƒ½æœƒè€ƒæ…®ä½¿ç”¨èƒ½å¤ æ¸›å°‘罹患å‰?列腺癌風險的藥物,例如Proscar。 ã€?PSAå’Œå‰?列腺癌風險】 為了進行這篇研究,Roobolå?šå£«å’Œå?Œäº‹å€‘ 臺灣新浪網

The best hair protection  -  04 Feb 2009
Your hairs will get acceleration in growth and get multiply to thousands due to proscar or generic propecia. Few online portals offer cheap propecia which NewDesignWorld (press release),

Pecharroman “Este deporte es demasiado duro para cargar con lo que ...  -  04 Feb 2009
...le impuso el Comité de Competición de la Federación Española de Ciclismo tras un positivo por ‘Proscar’, un medicamente para tratar casos de alopecia. Daimiel Noticias,

CAS overturns Pecharromán ban  -  Jan 27, 2009
Pecharromán admitted to taking a medicine called “Proscar� (marketed as Propecia in the United States) under advice from his doctor to treat apolecia, VeloNews,

Enlarged prostate: what treatments are there?  -  Jan 21, 2009
Drugs in this group are dutasteride (brand name Avodart) and finasteride (Proscar). Side effects can include problems getting an erection, guardian.co.uk,

Buy propecia online with best quality to control hair fall  -  Jan 28, 2009
Generic propecia or proscar is available in 1 mg tablets form to better the health of your hair. Propecia has a wonderful influence on male pattern hair NewDesignWorld (press release),

Polycystic ovary syndrome  -  Jan 21, 2009
These drugs include spironolactone (Aldactone) and finasteride (Proscar). They should only be prescribed by a specialist. You have to be careful not to get guardian.co.uk,

Overcoming the barriers  -  Jan 31, 2009
...launch of generic versions of the blockbuster drugs Zocor and Proscar, providing the company with 180-day market exclusivity for the generic versions. Pharmaceutical Technology Europe,

Incontinence, common among elderly, can be controlled  -  Jan 15, 2009
Urine outflow also can be improved by decreasing the size of the prostate with finasteride (Proscar) and dutasteride (Avodart). Great Falls Tribune,

Merck Announces Fourth-Quarter and Full-Year 2008 Financial Results  -  Feb 3, 2009
Other reported products comprise: ARCOXIA, CANCIDAS, COSOPT, CRIXIVAN, EMEND, FOSAMAX, INVANZ, ISENTRESS, MAXALT, PRIMAXIN, PROPECIA, PROSCAR, STOCRIN, Trading Markets (press release),

BUYINS.NET: Market Maker Surveillance Report. Top 6 Highest Net ...  -  Jan 30, 2009
Maxalt, an acute migraine product; Proscar to treat symptomatic benign prostate enlargement; Propecia for the treatment of male pattern hair loss; Trading Markets (press release),

El Tribunal de Arbitraje Deportivo anula su sanción de nueve meses  -  Jan 26, 2009
...por el uso del medicamento, 'Proscar', común para tratar casos de alopecia y que contiene finasteride, un enmascarador de los anabolizantes. El Mundo Deportivo,

Brand Names/Synonyms:
Proscar is also known by the following brand names and/or synonymsCCRIS 7438; Chibro-Proscar; Finasterida [Inn-Spanish]; Finasteride; Finasteride [Usan:Ban:Inn]; Finasteride and Its Intermediates; Finasteridum [Inn-Latin]; Finastid; Finpecia; HSDB 6793; MK-0906; MK-906; Propecia; Proscar; Prostide

Drug Category:
Proscar is categorized under the following by the FDA: Anti-baldness Agents; Antihyperplasia Agents; Skin and Mucous Membrane Agents (84:92.00); ATC:D11AX10; ATC:G04CB01

Dosage Forms:
TABLET

Absorption:
Not Available

Interactions:
-->Interactions for Finasteride:

No drug interactions of clinical importance have been identified. Finasteride does not appear to affect the cytochrome P450-linked drug-metabolizing enzyme system. Compounds that have been tested in man include antipyrine, digoxin, propranolol, theophylline, and warfarin and no clinically meaningful interactions were found.

Other concomitant therapy

Although specific interaction studies were not performed, finasteride doses of 1 mg or more were concomitantly used in clinical studies with acetaminophen, acetylsalicylic acid, a-blockers, analgesics, angiotensin-converting enzyme (ACE) inhibitors, anticonvulsants, benzodiazepines, beta blockers, calcium-channel blockers, cardiac nitrates, diuretics, H2 antagonists, HMG-CoA reductase inhibitors, prostaglandin synthetase inhibitors (also referred to as NSAIDs), and quinolone anti-infectives without evidence of clinically significant adverse interactions.

Drug/Laboratory Test Interactions

Finasteride had no effect on circulating levels of cortisol, thyroid-stimulating hormone, or thyroxine, nor did it affect the plasma lipid profile (e.g., total cholesterol, low-density lipoproteins, high-density lipoproteins and triglycerides) or bone mineral density. In studies with finasteride, no clinically meaningful changes in luteinizing hormone (LH), follicle-stimulating hormone (FSH) or prolactin were detected. In healthy volunteers, treatment with finasteride did not alter the response of LH and FSH to gonadotropin-releasing hormone indicating that the hypothalamic-pituitary-testicular axis was not affected.

In clinical studies with PROPECIA (finasteride, 1 mg) in men 18-41 years of age, the mean value of serum prostate-specific antigen (PSA) decreased from 0.7 ng/mL at baseline to 0.5 ng/mL at Month 12. Further, in clinical studies with PROSCAR (finasteride, 5 mg) when used in older men who have benign prostatic hyperplasia (BPH), PSA levels are decreased by approximately 50%. These findings should be taken into account for proper interpretation of serum PSA when evaluating men treated with finasteride.





Chemical IUPAC Name:
Not Available

:
 
Web health.mongabay.com/health


Health Home | Conditions | Cancer | Medications | Surgery | Vaccines

mongabay.com


Disclaimer:

Contact a physician with regard to health concerns. Email requests for further health information will be discarded.

The materials contained on this Web site are for informational purposes only and do not constitute health or medical advice. Use of information on this site does not create or constitute any kind of agreement or contract between you and the owners or users of this site, the owners of the servers upon which it is housed, or anyone else who is in any way connected with this site.

Many links on health.mongabay.com/health lead to other sites. health.mongabay.com/health does not sponsor, endorse or otherwise approve of the materials appearing in such sites. Nor is health.mongabay.com/health responsible for dead or misdirected links.

IF YOU NEED A LINK/TEXT REMOVED FROM THIS PAGE, PLEASE CONTACT: mongabay (at) gmail.com


COPYRIGHT 2007 MONGABAY.COM