|
 |
Primatene MistThis page contains recent news articles, when available, and an overview of Primatene Mist but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.Overview: Primatene Mist (when available) Epinephrine is indicated for intravenous injection in treatment of acute hypersensitivity, treatment of acute asthmatic attacks to relieve bronchospasm, and treatment and prophylaxis of cardiac arrest and attacks of transitory atrioventricular heart block with syncopal seizures (Stokes-Adams Syndrome). The actions of epinephrine resemble the effects of stimulation of adrenergic nerves. To a variable degree it acts on both alpha and beta receptor sites of sympathetic effector cells. Its most prominent actions are on the beta receptors of the heart, vascular and other smooth muscle. When given by rapid intravenous injection, it produces a rapid rise in blood pressure, mainly systolic, by (1) direct stimulation of cardiac muscle which increases the strength of ventricular contraction, (2) increasing the heart rate and (3) constriction of the arterioles in the skin, mucosa and splanchnic areas of the circulation. When given by slow intravenous injection, epinephrine usually produces only a moderate rise in systolic and a fall in diastolic pressure. Although some increase in pulse pressure occurs, there is usually no great elevation in mean blood pressure. Accordingly, the compensatory reflex mechanisms that come into play with a pronounced increase in blood pressure do not antagonize the direct cardiac actions of epinephrine as much as with catecholamines that have a predominant action on alpha receptors. For the treatment of Anaphylatic reactions Mechanism Of Action: Epinephrine works via the stimulation of alpha and beta-1 adrenergic receptors, and a moderate activity at beta-2 adrenergic receptors. News Articles on Epinephrine FDA: Asthma inhaler ban is coming - May 14, 2008 The makers of Primatene Mist are requesting the FDA delay the ban since the company says it won't be until 2009 or 2010 until their replacement product can WKYC-TV, Primatene Mist will be banned next year - Nov 29, 2007 Set to be banned outright by the Food and Drug Administration next year, Primatene Mist has already become scarce because of a shortage of a material used Billings Gazette, Public Meeting Scheduled for Ozone-Depleting Substance Ban - Nov 6, 2007 ...metered-dose inhalers (mdis) to include products containing epinephrine, such as Wyeth’s Primatene Mist. This article is viewable by subscribers only. FDA news (subscription), The Seven Wonders of the city of Stockton - 15 Oct 2007 Wonders of the Ancient World were all big, man made, and so breathtaking that they invariably made ancient travelers reach for their Primatene Mist. Stockton Record, Epinephrine CFC inhalers on the way out - Sep 25, 2007 Wyeth Consumer Healthcare, which has some three million US users of its Primatene Mist, would remove the product from shelves as of December 31, 2010, US-PharmaTechnologist.com, FDA Expands Ban on Ozone-Depleting Substances - Sep 25, 2007 At the meeting, Wyeth said it had been trying to reformulate Primatene Mist so it does not emit ODSs but ran into difficulties while avoiding patented FDA news (subscription), Over the Counter Asthma Inhalers Being Phased Out - Sep 25, 2007 Now, the FDA is proposing an expansion of the CFC ban to over the counter epinephrine inhalers, such as Primatene Mist. They would be removed from the About - News & Issues, Business news in brief - Sep 21, 2007 The proposal affects Primatene Mist, made by Wyeth, and other nonprescription inhalers used by millions of Americans.- Bloomberg News Melvyn Weiss, Philadelphia Inquirer, An unfriendly season - Jul 10, 2007 Norwich Bulletin,Some people rely on Primatene Mist, the only over-the-counter inhaler on the market, but Bundy warns this drug has been associated with heart problems. 'It could happen anywhere' - Jun 27, 2007 The Navasota Examiner,Primatene Mist asthma inhaler is a chemical cousin of adrenalin. Other over-the-counter medications can also be abused. That's not saying they're as bad as Expected Ban on Primatene Mist Raises Some Concerns May 11, 2006 Off the Shelf Primatene Mist, an asthma inhaler available without a prescription, could be removed from shelves because it uses an ozone-depleting propellant. ... - New York Times DAILY CHECK-UP May 14, 2006 ...superbugs.". Primatene Mist could be the next asthma inhaler banned because it uses a propellant harmful to the earth's ozone layer. ... - Kentucky.com Fired coach sues Loyola Apr 26, 2006 The documents say that Dirrigl was not using illegal drugs, but an over-the-counter inhaler called Primatene Mist for physical symptoms of stress and anxiety ... - Loyola College Greyhound (subscription) Environmental worries put pinch on inhalers Apr 6, 2006 Last month, an advisory panel to the FDA recommended that the agency ban the sale of CFC-powered Primatene Mist and similar over-the-counter inhalers used by ... - SunHerald.com Asthma inhalers in short supply, but local doctor talks silver ... Mar 14, 2006 The over-the-counter version of Primatene mist is a perfect example. Ponder says it's a popular low-cost substitute for the prescription Albuterol. ... - WATE.com Toilet Socialism 07 Mar 2006 ...yet another GOP contribution to limited government, an advisory committee at the Food and Drug Administration has recommended a ban on Primatene Mist, an over ... - National Review Online, Squeeze put on asthma inhalers Feb 27, 2006 Last month, an advisory panel to the FDA recommended that the agency ban the sale of CFC-powered Primatene Mist and similar over-the-counter inhalers used by ... - Monterey County Herald, EDITORIAL: Breathless Arrogance at the FDA Feb 11, 2006 11--An advisory panel to the US Food and Drug Administration has recommended that an over-thecounter asthma inhaler sold as Primatene Mist be taken off the ... - International News Service, Catching your breath Feb 18, 2006 In yet another Republican contribution to limited government, a Food and Drug Administration advisory committee has recommended a ban on Primatene Mist, an over ... - Washington Times, CFC ban ratchets up cost of asthmatics' rescue inhalers Feb 21, 2006 Last month, an FDA advisory panel recommended that the agency ban the sale of CFC-powered Primatene Mist and similar over-the-counter inhalers. ... - Chicago Tribune, Lobato: Breathe deep, the gathering gloom Feb 1, 2006 Primatene Mist, an over-the-counter inhaler for asthma, looks to be banned by the FDA soon, thanks to the "heroic" dual efforts of environmentalists and doctors ... - Broomfield Enterprise (subscription), Woe to an asthmatic Republican Feb 18, 2006 GOP contribution to limited government, an advisory committee for President Bush's Food and Drug Administration has recommended a ban on Primatene Mist, an over ... - Ocala.com, Brand Names/Synonyms: Primatene Mist is also known by the following brand names and/or synonymsADROP; Adnephrine; Adrenal; Adrenalin; Adrenalin Chloride; Adrenalin in Oil; Adrenalin-Medihaler; Adrenalina [Dcit]; Adrenaline; Adrenaline/Epinephrine; Adrenalinum; Adrenamine; Adrenan; Adrenapax; Adrenasol; Adrenatrate; Adrenine; Adrenodis; Adrenohorma; Adrenor; Adrenosan; Adrenutol; Adrin; Adrine; Aktamin; Alphacaine Hcl W/ Epinephrine; Ana-Guard; Antiasthmatique; Arterenol; Asmatane Mist; Asthma Meter Mist; Asthma-Nefrin; Asthmahaler Mist; Asthmanefrin; Astmahalin; Astminhal; Balmadren; Bernarenin; Biorenine; Bosmin; Brevirenin; Bronkaid; Bronkaid Mist; Bronkaid Suspension Mist; Bupivacaine Hcl and Epinephrine; CCRIS 4812; Chelafrin; Citanest Forte; Corisol; D-Adrenaline; D-Epifrin; D-Epinephrine; Drenamist; Duranest; Dylephrin; Dyspne-Inhal; Epi E Z Pen Jr; Epifrin; Epiglaufrin; Epinefrin; Epinefrin [Czech]; Epinefrina; Epinefrina [Inn-Spanish]; Epinephran; Epinephrine; Epinephrine Bitartrate; Epinephrine [Usan:Inn:Jan]; Epinephrinum [Inn-Latin]; Epipen; Epipen Auto-Injector; Epipen E Z Pen; Epipen Jr.; Epipen Jr. Auto-Injector; Epirenamine; Epirenan; Epirenin; Epitrate; Eppy; Esphygmogenina; Exadrin; Glaucon; Glaucosan; Glauposine; Glycirenan; HSDB 4289; Haemostasin; Haemostatin; Hektalin; Hemisine; Hemostasin; Hemostatin; Hypernephrin; Hyporenin; IOP; Intranefrin; Iontocaine; Isoptoepinal; Kidoline; L-Adrenalin; L-Adrenaline; L-Adrenaline Base; L-Adrenaline Gr; L-Arterenol; L-Epinephine; L-Epinephrine; L-Epirenamine; L-Methylaminoethanolcatechol; L-Noradrenaline; L-Norepinephrine; Levarterenol; Levo-Methylaminoethanolcatechol; Levoarterenol; Levoepinephrine; Levonor; Levonoradrenaline; Levonorepinephrine; Levophed; Levorenen; Levorenin; Levorenine; Lidocaine Hcl W/ Epinephrine; Lidocaine Hcl and Epinephrine; Lidocaton; Lyophrin; Medihaler-Epi; Metanephrin; Methylaminoethanolcatechol; Methylarterenol; Micronefrin; Mucidrina; Myosthenine; Mytrate; Nephridine; Nephron; Nieraline; Nor-Epirenan; Noradrenalin; Noradrenaline; Norartrinal; Norepinephrine; Norepinephrine Bitartrate; Norepirenamine; Octocaine; Paranephrin; Primatene Mist; Procaine Hcl W/ Epinephrine; Rcra Waste No. P042; Rcra Waste Number P042; Renagladin; Renaglandin; Renaglandulin; Renaleptine; Renalina; Renoform; Renostypricin; Renostypticin; Renostyptin; S-2; Scurenaline; Septocaine; Simplene; Sindrenina; Soladren; Sphygmogenin; Stryptirenal; Styptirenal; Supracapsulin; Supradin; Supranefran; Supranephrane; Supranephrine; Supranol; Suprarenaline; Suprarenin; Suprel; Surenine; Surrenine; Sus-Phrine; Susphrine; Sympathin E; Sympathin I; Takamina; Takamine; Tokamina; Tolansin; Tolax; Tolcil; Tolhart; Tonogen; Twinject; Twinject 0.30; Vaponefrin; Vasoconstrictine; Vasoconstrictor; Vasodrine; Vasoton; Vasotonin; Xylocaine W/ Epinephrine Drug Category: Primatene Mist is categorized under the following by the FDA: Vasoconstrictor Agents; Mydriatics; Bronchodilator Agents; Sympathomimetic; ATC:A01AD01; ATC:B02BC09; ATC:C01CA03; ATC:C01CA24; ATC:R01AA14; ATC:R03AA01; ATC:S01EA01 Dosage Forms: CORD; DROPS; LIQUID; METERED-DOSE (AEROSOL); PAD; PELLET; PELLET (DENTAL); SOLUTION; SPRAY Absorption: Usually this vasodilator effect of the drug on the circulation predominates so that the modest rise in systolic pressure which follows slow injection or absorption is mainly the result of direct cardiac stimulation and increase in cardiac output. Interactions: Interactions for Epinephrine: Epinephrine should be used cautiously in patients with hyperthyroidism, hypertension and cardiac arrhythmias. All vasopressors should be used cautiously in patients taking monoamine oxidase (MAO) inhibitors. Epinephrine should not be administered concomitantly with other sympathomimetic drugs (such as isoproterenol) because of possible additive effects and increased toxicity. Combined effects may induce serious cardiac arrhythmias. They may be administered alternately when the preceding effect of other such drug has subsided. Administration of epinephrine to patients receiving cyclopropane or halogenated hydrocarbon general anesthetics such as halothane which sensitize the myocardium, may induce cardiac arrhythmia.. When encountered, such arrhythmias may respond to administration of a beta-adrenergic blocking drug. Epinephrine also should be used cautiously with other drugs (e.g., digitalis, glycosides) that sensitize the myocardium to the actions of sympathomimetic drugs. Diuretic agents may decrease vascular response to pressor drugs such as epinephrine. Epinephrine may antagonize the neuron blockade produced by guanethidine resulting in decreased antihypertensive effect and requiring increased dosage of the latter. Chemical IUPAC Name: 4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol : |
|
Health Home | Conditions | Cancer | Medications | Surgery | Vaccines mongabay.com
COPYRIGHT 2007 MONGABAY.COM |