Pravachol

This page contains recent news articles, when available, and an overview of Pravachol but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Pravachol
(when available)

Pharmacology and use:
Pravastatin, an antilipemic agent, is used to treat primary hypercholesterolemia. Unlike lovastatin and simvastatin, pravastatin is relatively hydrophilic and does not require hydrolysis for activation. For the treatment of hypercholesterolemia to reduce the risk of myocardial infarction.

Mechanism Of Action:
Like lovastatin and simvastatin, pravastatin inhibits hydroxymethylglutaryl-CoA (HMG-CoA) reductase. As HMG-CoA is necessary for the intracellular synthesis of cholesterol, its inhibition results in increased clearance of circulating LDL. Pravastatin also inhibits hepatic synthesis of VLDL, the precursor for LDL, reducing circulating cholesterol and LDL cholesterol.

News Articles on Pravastatin

Statin drugs do not prevent dementia  -  20 Apr 2009
Left to right, Lipitor (atorvastatin calcium), Pravachol (prevastatin), and Zocor (simvastatin). NEW YORK (Reuters Health) - Statin drugs, Canada.com

Statins work better in summer  -  ‎Apr 19, 2009‎
Drugs such as Levacor, Zocor, Pravachol, Lipitor, and Crestor, classified as statins, reduce the risk of developing atherosclerosis and subsequent PRESS TV

Statins Cut Stroke Risk by One-Fifth in Meta-Analysis  -  ‎Apr 14, 2009‎
Other drugs tested in the trials included rosuvastatin (Crestor), pravastatin (Pravachol), atorvastatin (Lipitor), and lovastatin (Mevacor). MedPage Today

Study: Cholesterol drug lowers blood clot risk  -  ‎Mar 29, 2009‎
Its sales have been rising even though two statins — Zocor and Pravachol — are now available in generic form. Researchers do not know whether the benefits The Associated Press

Helping the Unemployed Save Money and Protect Their Health  -  ‎Apr 10, 2009‎
A 90 day supply of generic Pravastatin (Pravachol) is available for $10 at www.walmart.com. About the author: Dr. Michael Cecil is a cardiologist with six NewsBlaze

Grapefruit and Prescription Drugs: Mix Carefully  -  ‎Mar 30, 2009‎
...prescribed drugs for lowering cholesterol have been added to the list -- well-known drugs such as Lipitor, Mevacor, and Zocor (but not Pravachol). Online - International News Network

Salute/ Le statine riducono il rischio formazione dei trombi  -  ‎Mar 30, 2009‎
...il prezzo piuttosto alto: 3.45 dollari al giorno contro meno di un dollaro del farmaco generico con lo stesso principio attivo (del Zocor o Pravachol). Wall Street Italia

Cholesterol Drugs Linked to Increased Fatigue  -  ‎Mar 12, 2009‎
...prove that the medications make people tired, and heart specialists remain skeptical about the study, which focused on two statins, Pravachol and Zocor. U.S. News & World Report

Satin drugs: A health hazard?  -  ‎Mar 16, 2009‎
According to news reports, statin drugs (Lipitor, Zocor, Pravachol, Crestor, Lescol and Mevacor) are the most effective cholesterol-lowering drugs available Merinews

Statins could hurt your sex life  -  ‎Mar 10, 2009‎
Pravastatin, or Pravachol, reduced LDL less and didn't have a significant effect on orgasms. The study was presented at a conference of the American Chicago Sun-Times

Bristol-Myers Squibb Co. (BMY)  -  ‎Mar 12, 2009‎
The Pharmaceutical segment manufactures and sells branded pharmaceutical drugs such as Pravachol for cholesterol reduction, Plavix for hypertension and Zacks.com

Study: Statins Lower Sexual Pleasure Along With Cholesterol  -  ‎Mar 6, 2009‎
Some were given Zocor or Pravachol and some took a placebo. Those posting the biggest drop in their bad cholesterol level also reported having more trouble Ozarks First

Loss of Power Could Stem From Medication  -  ‎Mar 11, 2009‎
He writes: “Statin drugs (Lipitor, Zocor, Pravachol, Crestor, Lescol and Mevacor) are the most effective cholesterol-lowering drugs available. Korea Times

Cholesterol Drugs May Help Asthma Patients  -  ‎Mar 16, 2009‎
The other patients were on Pravachol, Mevacor, Lescol, or a combination of drugs. Over a one-year period, 20.5% of patients taking statins were hospitalized WebMD

FDA: Ranbaxy falsified data on drug applications  -  ‎Feb 25, 2009‎
...pravastatin (Pravachol) and imvastatin (simvastatin), and the antihistamine pheniramine (Avil), the agency said in a teleconference today. FiercePharma

Do cholesterol drugs really work?  -  ‎Feb 25, 2009‎
...(Statins are: Zocor, Pravachol, Crestor, Lescol, Mevacor and Lipitor.) Muscle pain occurs in 1 in 1000 users. Muscle damage occurs in much fewer. Payson Roundup

Health insurers push generics, but what are patients getting?  -  ‎Mar 8, 2009‎
For example, the alternatives for cholesterol-lowering Lipitor include simvastatin (generic for Zocor) and pravastatin (generic for Pravachol). Chicago Tribune

Statins Cut Deaths From Prostate Cancer  -  ‎Feb 26, 2009‎
Zocor, and Crestor were linked to a lower risk of dying from prostate cancer even more than weaker statins like Mevacor, Pravachol, and Lescol. WebMD

Can herpes carrier have safe sex?  -  ‎Mar 2, 2009‎
Zocor and Lipitor are affected by grapefruit, but Pravachol and Crestor are not. In their column, Joe and Teresa Graedon answer letters from readers. Seattle Times

New study supports statin's anti-dementia effects  -  ‎Mar 2, 2009‎
An example of a water soluble statin is pravastatin (Pravachol). The protective effect of statin use against Alzheimer's disease was also similar for Canada.com

Статины могут вызывать повышенную утомлÑ?емоÑ?ть  -  ‎Mar 15, 2009‎
Два лекарÑ?тва Pravachol и Zocor были изучены в Ñ?том иÑ?Ñ?ледовании. Ученые не утверждают, что препараты провоцируют упадок Ñ?ил. «У наÑ? нет доказательÑ?тва МЕДСТРИМ.РУ - консультации врачей, новости медицины

스타틴 복용하는 사람, 피로ê°? 잘 ëŠ?ê»´  -  ‎Mar 12, 2009‎
...성ì?¸ 1016명ì?„ 세 그룹으로 나눠 한 그룹ì?€ 20mg 'ì¡°ì½”(Zocor)'를 ë‘?번째 그룹ì?€ 40mg '프ë?¼ë°”콜(Pravachol)', 나머지 그룹ì?€ 위약ì?„ 6개월 ë?™ì•ˆ 복용하게 했다. 데일리팜

Le statine fanno bene al colesterolo, ma fanno male al sesso  -  ‎Mar 8, 2009‎
In Italia questo farmaco è venduto sotto diversi marchi tra cui Elisor, Pravachol, Pravasin, Pravastatin, Pravastatin sodium, Pravastatina, Pravastatine, La Stampa

The Tale of 2 Drugmakers  -  04 Feb 2009
AstraZeneca's (NYSE: AZN) Crestor, or generic versions of statins such as Merck's Zocor or Bristol-Myers Squibb's (NYSE: BMY) Pravachol. Motley Fool

Attacking high cholesterol  -  04 Feb 2009
...we have atorvastatin (Lipitor), cerivastatin (Baycol, Lipobay), fluvastatin (Lescol), pravastatin (Pravachol), rosuvastatin (Crestor), and simvastatin Jamaica Gleaner,

New study finds downplay of drug side effects  -  Jan 28, 2009
Golomb urged patients and doctors to look more closely at the list of possible side effects from such drugs as Lescol, Pravachol, Zocor and Lipitor, La Jolla Light,

Steven Nissen: Which Statin Is Right for Me?  -  Jan 26, 2009
And the most commonly used statins that are generic are pravastatin (known as Pravachol), or simvastatin (brand name Zocor). Pravachol is a relatively weak U.S. News & World Report,

Excess cholesterol controlled by lipitor  -  Feb 1, 2009
Lipitor pravachol is a real lipitor drug that has concentrated ingredients that removes LDL, a lipoprotein which paces risk of heart diseases, NewDesignWorld (press release),

Kidney, Heart Problems May Be Linked  -  Jan 21, 2009
The study, originally started to learn whether the medication pravastatin (Pravachol), a statin, affected the development of cardiovascular disease, Washington Post,

Manhattan Research Releases Top Pharma Brand Product Sites by ...  -  Feb 3, 2009
Paxil, Plavix, Pravachol, Prevacid, Protonix, Provigil, Pulmicort, , Restasis, Risperdal, Rozerem, Seasonale, Seroquel, Singulair, Strattera, Tamiflu, PR Web (press release),

CoQ10, ubiquinol same nutrient, but differ in quality, brands  -  Jan 17, 2009
Leg cramps and muscle pain can be the result of the drug mugging effect of statin cholesterol medicines such as Advicor, Pravachol, Zocor, Lipitor, Tulsa World,

Firm joins drug giant in venture  -  Jan 13, 2009
Many pharmaceuticals are polyketides, such as the anti-cholesterol drugs Mevacor, Pravachol and Zocor; the anticancer drugs Torisel and Ixempra; Pharmacy Europe,

Bristol-Myers Swings To 4Q Profit;Plavix, Abilify Sales Grow  -  Jan 27, 2009
Another cholesterol drug, Pravachol, reported a 70% drop as generic versions take greater hold in the market. Abilify, an antipsychotic treatment, CNNMoney.com

Pharmas offer gloomy 2009 forecasts  -  Jan 27, 2009
Plavix revenues rose by 7 percent, helping to take up the slack from a 70 percent loss of Pravachol sales because of generic competition. FiercePharma,

New study supports statin's anti-dementia effects  -  Jan 9, 2009
An example of a water soluble statin is pravastatin (Pravachol). The protective effect of statin use against Alzheimer's disease was also similar for MSNBC

Millions More Americans Might Be Placed on Statins  -  Jan 13, 2009
Statins include blockbuster medications such as Crestor, Lipitor, Pravachol and Zocor. But what about people who have normal levels of LDL cholesterol, Washington Post,

Thanks for Nothing, FDA  -  Jan 9, 2009
AstraZeneca's (NYSE: AZN) Crestor, or generic versions of statins such as Merck's Zocor or Bristol-Myers Squibb's (NYSE: BMY) Pravachol. Motley Fool

What you can do after a heart attack  -  Jan 21, 2009
...[2] Some common statins are atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Mevacor), pravastatin (Pravachol) and simvastatin (Zocor). guardian.co.uk,

Supplements: Are they worth it?  -  Jan 20, 2009
...foreign countries -- all of which depletes important nutrients, she says. n Statin drugs (Lipitor, Zocor, Pravachol) deplete antioxidant coenzyme Q10. Brantford Expositor,

Production and Purification of Esters of Polyunsaturated Fatty Acids  -  Jan 22, 2009
LIPITOR (atorvastatin calcium), LESCOL (fluvastatin), LOPID (gemfibrozil), or PRAVACHOL (pravastatin sodium)); policosanols; fibrates; Clioquinol; FLEXNEWS,

Nuevo estudio respalda efectividad de estatinas contra demencia  -  Jan 14, 2009
Un ejemplo de la estatina soluble en agua es la pravastatina (Pravachol). El efecto protector de las estatinas frente al Alzheimer se mantuvo en personas Buena Salud

Millones más de estadounidenses podrían empezar a tomar estatinas  -  Jan 16, 2009
Entre las estatinas se encuentran medicamentos de gran éxito de ventas como Crestor, Lipitor, Pravachol y Zocor. ¿Pero qué pasa por con las personas que Info7,

LÄKEMEDEL: RANBAXY KAN FLYTTA VISS PRODUKTION TILL USA  -  Jan 15, 2009
Bland de preparat som blockerades ingick en kopieversion av Bristol-Myers Squibbs kolesterolpreparat Pravachol. Dagens Nyheter,

El colesterol es tu mejor amigo  -  Jan 28, 2009
...a surgir todos los efectos secundarios del veneno que es Crestor (y todas las otras statinas como Lipitor, Vytorin, Mevacor, Pravachol, Zocor y Caduet). Claridad,

Why Statins Don't Work in 1 in 5 People  -  Dec 17, 2008
If they're taking a less powerful statin, like Pravachol or Zocor, they would probably benefit from switching to a more powerful drug like Crestor or U.S. News & World Report,

Should statins be available for everyone?  -  Dec 19, 2008
All six statins available today -- atorvastatin (Lipitor), rosuvastatin (Crestor), simvastatin (Zocor), lovastatin (Mevacor), pravastatin (Pravachol) and Los Angeles Times,

Gene mutations linked to statin resistance  -  Dec 21, 2008
The statins tested included atorvastatin (Lipitor), simvastatin (Zocor), and pravastatin (Pravachol). Researchers wanted to study statins at two dose levels The Virtual Medical Centre,

Generic drug maker suit against federal government reaches trial stage  -  Dec 15, 2008
The generics point to lower-cost equivalents of popular medicines such as the antidepressants Zoloft and Wellbutrin, or Pravachol, a drug that lowers The Canadian Press,

Ellen McDonald Joins Regado Biosciences as Senior Vice President ...  -  Dec 2, 2008
She was responsible for leading the growth in sales of Plavix(R), the second-largest-selling drug in the world last year, Pravachol(R) and Avapro(R). MarketWatch

The Power of Statins  -  Dec 6, 2008
This concept led to the development of cholesterol-lowering statins, such as Mevacor (lovastatin), Zocor (simvastatin), Pravachol (pravastatin), Lipitor, Newsweek

Bristol-Myers Squibb Co.  -  Dec 10, 2008
The Pharmaceutical segment manufactures and sells branded pharmaceutical drugs such as Pravachol for cholesterol reduction, Plavix for hypertension and Zacks.com,

Can Bristol-Myers Squibb Co. Break Through Resistance?  -  Dec 10, 2008
Some of the firm's cardiovascular drugs include heart disease drug Plavix, as well as Pravachol (which lowers cholesterol) and Avapro (for hypertension). Schaeffers Research,

Médicaments génériques: la Cour fédérale se penche sur les règlements  -  Dec 15, 2008
...si les règlements avaient été en place avant 2006, tels que les antidépresseurs Zoloft et Wellbutrin, et le Pravachol, censé réduire le taux de cholestérol. La Presse Canadienne,

10 أخبار صحية كبرى.. لعام 2008  -  Dec 20, 2008
وقد انطلقت الادوية باسماء اصلية نتيجة اسباب عديدة، منها ان العقاقير العملاقة (مثل Fosamax, Pravachol, Zocor, Zoloft) قد Ù?قدت حماية براءات اختراعها Ù?ÙŠ الشرق الاوسط,

Brand Names/Synonyms:
Pravachol is also known by the following brand names and/or synonymsCCRIS 7557; Compactin; Elisor; Lipostat; Lovastatin; Mevalotin; Mevastatin; Mevinolin; Oliprevin; Pravachol; Pravaselect; Pravastatin; Pravastatin Sodium; Pravastatina [Spanish]; Pravastatine [French]; Pravastatinum [Latin]; Selectin; Selipran; Vasten

Drug Category:
Pravachol is categorized under the following by the FDA: Anticholesteremic Agents; HMG-CoA Reductase Inhibitors; ATC:C10AA03

Dosage Forms:
TABLET

Absorption:
Average oral absorption of pravastatin is 34% and absolute bioavailability is 17%.

Interactions:
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Chemical IUPAC Name:
3,5-dihydroxy-7-[6-hydroxy-2-methyl-8-(2-methylbutanoyloxy)-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-heptanoicacid

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