Percocet

This page contains recent news articles, when available, and an overview of Percocet but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Percocet
(when available)

Pharmacology and use:
Oxycodone, a semisynthetic opiate agonist derived from the opioid alkaloid, thebaine, is similar to other phenanthrene derivatives such as hydrocodone and morphine. Oxycodone is available in combination with aspirin or acetaminophen to control pain and restless leg and Tourette syndromes. For the treatment of diarrhoea, pulmonary oedema; For the relief of moderate to moderately severe pain

Mechanism Of Action:
Oxycodone acts as a weak agonist at OP1, OP2, and OP3 opiate receptors within the central nervous system (CNS). Oxycodone primarily affects OP3 receptors, which are coupled with G-protein receptors and function as modulators, both positive and negative, of synaptic transmission via G-proteins that activate effector proteins. Binding of the opiate stimulates the exchange of GTP for GDP on the G-protein complex. As the effector system is adenylate cyclase and cAMP located at the inner surface of the plasma membrane, opioids decrease intracellular cAMP by inhibiting adenylate cyclase. Subsequently, the release of nociceptive neurotransmitters such as substance P, GABA, dopamine, acetylcholine, and noradrenaline is inhibited. Opioids such as Oxycodone also inhibit the release of vasopressin, somatostatin, insulin, and glucagon. Opioids close N-type voltage-operated calcium channels (OP2-receptor agonist) and open calcium-dependent inwardly rectifying potassium channels (OP3 and OP1 receptor agonist). This results in hyperpolarization and reduced neuronal excitability.

News Articles on Oxycodone

AP couple arrested for trafficking drugs  -  30 Aug 2009
SEBRING - An Avon Park couple tried to pass off a fraudulent prescription for 120 Percocet and wound up in jail after pharmacists Tampa Tribune

A Local Life: Emily Dao, 20  -  30 Aug 2009
She took Percocet, an oral opiate painkiller, every three to four hours. The chemotherapy and medications made her nauseated. Every day she vomited what Washington Post

Sub Base CO Wants 'Two-Way Street'  -  30 Aug 2009
Denno referred to the incident as “my percocet story,� and joked, “The Coast Guard interview went badly, I am told, because I'm not sure I was there for it. TheDay

MoxDuo(TM) IR Demonstrates Fewer Side Effects Than Percocet(R)  -  ‎Aug 26, 2009‎
When compared at equianalgesic doses with Percocet(R), the second most widely prescribed opioid in the US, MoxDuo(TM) IR demonstrated greater overall PR Newswire (press release)

Ex-nurse stole drugs at hospital, attorney general says  -  ‎Aug 28, 2009‎
Nurse Gray checked the computerized system that dispenses and tracks patients' pain medication and found her patient had Percocet signed out to him multiple Sharon Herald

MoxDuoIR Demonstrates Fewer Side Effects than Percocet  -  ‎Aug 24, 2009‎
...four to six hours over a 48hour period. The study enrolled a total of 44 patients at dosing regimen of MoxDuoTM IR against a fixed low dose (3/2mg). Sydney Morning Herald

Man allegedly found with drugs  -  ‎Aug 28, 2009‎
A police search revealed he was carrying 3.5 grams of cocaine and three generic Percocet pills, Saccente said. He was charged with possession of narcotics, New Britain Herald

Some patients concerned over new recommendations for acetaminophen use  -  ‎Aug 24, 2009‎
..."Acetaminophen works as a great adjunct with narcotic painkillers, like the main ingredient in Lortab or Percocet. It has a synergistic effect," he said, StandardNet

Vicodin, Tylenol among drugs FDA scrutinizing  -  ‎Aug 14, 2009‎
For example, a single dose of Percocet can contain 650 milligrams of acetaminophen, which is just 350 milligrams short of the current recommended maximum San Francisco Chronicle

A Nurse Reviews 'Nurse Jackie'  -  ‎Aug 5, 2009‎
At the start of the series Jackie's use of prescription painkillers was used for dramatic effect (for example, crushing Percocet to sprinkle into her New York Times

QrxPharma's MoxDuoâ„¢ IR drug demonstrates fewer side effects than ...  -  ‎Aug 24, 2009‎
When compared at equianalgesic doses with Percocet®, the second most widely prescribed opioid in the US, MoxDuo™ IR demonstrated greater overall Proactive Investors Australia

Youth prescription drug abuse on the rise in Vt  -  ‎Aug 21, 2009‎
The Times Argus reports Cimaglio said the prescription drugs involved usually are prescribed for pain, including OxyContin, Percocet, Vicodin and Darvon. Newsday

Courtney Love: If the Hooker Shoe Fits...  -  ‎Aug 21, 2009‎
Love also says Dawn admitted to "drug and alcohol abuse" and even tried to get Courtney to take cocaine and Percocet. Courtney says she spilled Dawn's beans TMZ.com

14 targeted in Franklin drug sweep  -  ‎Aug 26, 2009‎
...detectives bought crack and powder cocaine, and various prescription pills, including OxyContin, Percocet, hydrocodone, Lortab and liquid morphine. Kentucky.com

Broward man on alcohol, drugs in St. Lucie drives erratically ...  -  ‎Aug 27, 2009‎
Hyshon J. Pittman, 33, admitted ingesting vodka, Percocet and Xanax several hours before the traffic stop near Indrio Road and Kings Highway, TCPalm

Heidi Montag: Heir To Britney's Crown!  -  ‎Aug 24, 2009‎
At least Britney had champagne and Percocet to hang her crown on -- what's Heidi's excuse? Take a gander at the horrific video below and decide if "The New York Post

Lindale man arrested on drug charges  -  ‎Aug 25, 2009‎
...nervous on Avenue C. When stopped for questioning, Bell allegedly kept grabbing his pants pocket. He was found with Percocet pills, a schedule II drug. Rome News Tribune

York dentist forced to give up license  -  ‎Aug 19, 2009‎
...attempted delivery of a controlled substance. Authorities said he wrote a prescription for the pain reliever Percocet for a woman whom he never examined. KHAS-TV

Cancer I Can't Afford  -  ‎Aug 12, 2009‎
The first bill arrived while I lay in bed in a post-operative Percocet-induced haze: $13805 for outpatient, same-day surgery. “That's just a statement, New York Times

Flexcin Arthritis Remedy Proves Worthy Substitution for Acetaminophen  -  ‎Aug 26, 2009‎
Acetaminophen, along with prescription pain medications like Vicodin and Percocet, have all recently made headlines attracting consumers' attention because Earthtimes (press release)

Nurse fired for stealing pills from patient's purse  -  ‎Aug 26, 2009‎
On several occasions in 2005, the nurse had falsified medication control forms in order to acquire Percocet and Supeudol pills. She also stole medication The Kingston Whig-Standard

Docs cringe at the thought of painkillers taken off the market  -  ‎Aug 19, 2009‎
In July, an advisory panel recommended to the FDA the ban of the painkillers Vicodin and Percocet. A month later, the one thing the experts still haven't Medill Reports: Washington

Shots Fired Lead To Man's Arrest On Drug Charges  -  ‎Aug 25, 2009‎
When police confronted him, he allegedly dropped two bags; one containing Percocet pills, the other marijuana. He's facing two counts of possession as a WCPO

Disabled man says he was robbed on Jensen Beach Causeway  -  ‎Aug 25, 2009‎
Between that time and 3 am, the man said someone stole $248 from his wallet, his cell phone and two bottles of Oxycontin and Percocet from him, Stuart News (subscription)

Stolen prescription forms used to get drugs  -  ‎Aug 18, 2009‎
MONTICELLO – An Otisville woman was arrested by Monticello Police and charged with felonies for allegedly using stolen prescription forms to obtain Percocet CatskillsNews.com

Ibuprofen as good as nacortic painkiller for kids' fracture pain  -  ‎Aug 18, 2009‎
The advisory panel noted that acetaminophen and hydrocone (eg, Vicodin) and acetaminohen and oxycodone (eg, Percocet) had liver and other risks that Examiner.com

Valley father tells story to prevent another drug tragedy  -  ‎Aug 23, 2009‎
He had taken what some refer to as a "cocktail," combining the prescription drugs Oxycontin, Percocet and Xanax with alcohol, overloading his young body ABC15.com (KNXV-TV)

CRIME REPORTS  -  ‎Aug 25, 2009‎
Jewelry and 146 Percocet pills were stolen from a home on the first block of Gay Street between 8 am Saturday and 6 pm Sunday. A vehicle was struck with a The Newark Advocate

Man must leave if girlfriend says  -  ‎Aug 27, 2009‎
The RCMP laid the charge after recovering three Percocet pills from Flynn's shoe at Wilson's Beach. He came to court also for sentencing for a charge of Telegraph-Journal

Ellenville teen faces drug charges after stop  -  ‎Aug 24, 2009‎
ELLENVILLE — Alexander Dumond, 18, of Napanoch was charged after troopers say they found Diazepam and Percocet after pulling him over on Irish Cape Road in Times Herald-Record

3 Staten Island teens hit with drug charges  -  ‎Aug 21, 2009‎
She also had a metal container, which held nine Percocet pills, according court papers. Percocet is a prescription pain reliever. Staten Island Advance - SILive.com

TO Music Notes  -  ‎Aug 26, 2009‎
...“I finally had surgery and then recuperated in PEI,� Murphy tells us. “I've weened myself off Percocet and am ready to rock.� NOW Toronto

Police charge man with forging prescriptions  -  ‎Aug 18, 2009‎
Portland police last week arrested a 54-year-old man who is accused of forging dozens of prescriptions for Percocet, OregonLive.com

Woman faces 6 felonies alleging prescription fraud  -  ‎Aug 15, 2009‎
...a controlled drug by fraud, in addition to a misdemeanor charge of theft from a building alleging she stole 10 Percocet tablets from a family member. Seacoastonline.com

License suspended for doctor facing drug charges  -  ‎Aug 21, 2009‎
Vittone began treating Miller in 2006 for pain, at first legitimately prescribing Percocet, Valium and Ativan, according to a criminal complaint. The Tribune-Democrat

Ten arrested in two-state meth ring bust  -  ‎Aug 27, 2009‎
Terry Nobles, 46, of Westville, charged purchase of meth, possession of Percocet and possession of drug paraphernalia. - Silas Lavell Nobles, 20, The News Herald

Narcotics Stolen From Vestal Pharmacy  -  ‎Aug 3, 2009‎
Police are still trying to figure out what drugs were taken, they said he specifically wanted Percocet or Vicodin. They say the store does have cameras, FOX 40 News WICZ TV

Law and Order  -  ‎Aug 21, 2009‎
These include 35 syringes of Dilauded (hydromophone), five tablets of Lortab (hydromorphone and acetaminophen) and two tablets of Percocet (oxycodone and Gary Post Tribune

FDA Concern Highlights Even The Most Common Drugs Are Still  -  ‎Aug 19, 2009‎
...products like Tylenol and Excedrin and combine acetaminophen with narcotics like oxycodone (found in Percocet) and Hydrocodone (in Vicodin). TransWorldNews (press release)

Falmouth police say officer saved woman who overdosed  -  ‎Aug 18, 2009‎
Police declined to identify the woman but said she overdosed on Percocet and was taken to Falmouth Hospital for treatment. After further investigation Cape Cod Times

Coopersburg man uses forms stolen from dentist to buy painkillers ...  -  ‎Aug 11, 2009‎
1 purchase of Percocet at the Kmart on 1504 S. Fourth St. Video and documents confirmed Counterman bought 60 pills there, city police said in their Allentown Morning Call

Saturday's Crime Report  -  ‎Aug 7, 2009‎
Officers seized 50 Percocet pain pills valued at $500 and $818. Bail for each was set at $100000. CARTHAGE: Harry Hamilton, 50, of the 100 block of McQueen FayObserver.com

Woman says she was robbed by hatchet-wielding man  -  ‎Aug 17, 2009‎
The suspected robber then allegedly asked the woman if her Percocet pills were inside the container. When she said they were, he told her they had better be Daily Post Athenian

Woman robs North Side pharmacy, escapes with drugs  -  ‎Aug 16, 2009‎
The woman left the pharmacy on foot after the clerk handed over an unidentified number of Percocet and OxyContin pills, said Evansville Police Department Evansville Courier & Press

Teens Taking Opioids to Relax, Get High  -  ‎Aug 6, 2009‎
6, 2009 -- American teens are using prescription opioids -- such as Vicodin, OxyContin, Percocet, and codeine -- without a doctor's orders at an alarmingly WebMD

Woman says man is stalking her  -  ‎Aug 17, 2009‎
Rockingham. n A Pineridge Road resident had $10 worth of Percocet stolen out of her purse. n An industrial business on East Broad Street had property Richmond County Daily Journal

St. John's pharmacy robbed at gunpoint  -  ‎Aug 7, 2009‎
The thief also stuffed narcotics like OxyContin and Percocet into the bags. Hollahan said that as soon as the bags were full, the thief ran out of the CBC.ca

Brand Names/Synonyms:
Percocet is also known by the following brand names and/or synonymsCodeinone, Dihydrohydroxy-; Combunox; Dea No. 9143; Dihydrohydroxycodeinone; Dihydrohydroxycondeinone; Dihydrone; Dihydroxycodeinone; Dinarkon; Diphydrone; ENDOCET; ENDODAN; Endone; Eubine; Eubine [France]; Eucodal; Eucodalum; Eukodal; Eutagen; HSDB 3142; Ossicodone [Dcit]; Oxanest; Oxicodona [Inn-Spanish]; Oxicon; Oxicone; Oxikon; Oxycet; Oxycodeinone; Oxycodon; Oxycodone; Oxycodone Hcl; Oxycodone Hydrochloride; Oxycodone [Usan:Ban:Inn]; Oxycodonum [Inn-Latin]; Oxycon; Oxycontin; PERCOCET; Pancodine; Percobarb; Percocet; Percodan; Roxicet; Roxicodone; Roxilox; Supendol [Canada]; Tecodin; Tekodin; Thecodine; Thekodin; Tylox

Drug Category:
Percocet is categorized under the following by the FDA: Narcotics; Antitussives; Analgesics, Opioid; Opiate Agonists; ATC:N02AA05

Dosage Forms:
Tablet; Suppository

Absorption:
well absorbed from OxyContin® tablets with an oral bioavailability of 60% to 87%

Interactions:
Interactions for Oxycodone:

The CNS depressant effects of oxycodone hydrochloride may be additive with that of other CNS depressants..





Chemical IUPAC Name:
4, 5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one

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