Percocet

This page contains recent news articles, when available, and an overview of Percocet but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Percocet (when available)

Pharmacology and use:
Oxycodone, a semisynthetic opiate agonist derived from the opioid alkaloid, thebaine, is similar to other phenanthrene derivatives such as hydrocodone and morphine. Oxycodone is available in combination with aspirin or acetaminophen to control pain and restless leg and Tourette syndromes. For the treatment of diarrhoea, pulmonary oedema; For the relief of moderate to moderately severe pain

Mechanism Of Action:
Oxycodone acts as a weak agonist at OP1, OP2, and OP3 opiate receptors within the central nervous system (CNS). Oxycodone primarily affects OP3 receptors, which are coupled with G-protein receptors and function as modulators, both positive and negative, of synaptic transmission via G-proteins that activate effector proteins. Binding of the opiate stimulates the exchange of GTP for GDP on the G-protein complex. As the effector system is adenylate cyclase and cAMP located at the inner surface of the plasma membrane, opioids decrease intracellular cAMP by inhibiting adenylate cyclase. Subsequently, the release of nociceptive neurotransmitters such as substance P, GABA, dopamine, acetylcholine, and noradrenaline is inhibited. Opioids such as Oxycodone also inhibit the release of vasopressin, somatostatin, insulin, and glucagon. Opioids close N-type voltage-operated calcium channels (OP2-receptor agonist) and open calcium-dependent inwardly rectifying potassium channels (OP3 and OP1 receptor agonist). This results in hyperpolarization and reduced neuronal excitability.

News Articles on Oxycodone

Graduates: Marsh  -  03 Jul 2008
Lynn Graham Marsh, principal of WR Odell Elementary School in Cabarrus County, recently received a Ph.D. in business administration from Warren National Salisbury Post,

Drugs, theft, sexual slurs and rows with her husband: The murky ...  -  03 Jul 2008
The first meant she was "on [the prescription drug] Percocet" and it was a good day, the second meant she was "not on Percocet" and it really wasn't. Daily Mail,

Police: 3 charged in connection with drug deal that went wrong  -  03 Jul 2008
The men said Ms. Grieneisen gave them about $200 to buy Percocet and $25 for gasoline to drive to New Castle to get the pills, police said. Sharon Herald,

Man high on Percocet while driving, Framingham cops say  -  Jun 30, 2008
Matthew P. Adams, 42, admitted he had taken Percocet before driving, and yelled and screamed at officers when they told him he was going to be arrested, MetroWest Daily News,

2008-07-02 20:11:18 - www.companiesandmarkets.com adds new report ...  -  Jul 2, 2008
The company has a portfolio of branded products that includes: Lidoderm, Percocet, Frova, Percodan, Opana, Opana ER and Synera. The company´s lead product PR-Inside.com (Pressemitteilung),

Everyone Knows it's Cindy (Except Newsweek)  -  Jul 1, 2008
That Cindy had been addicted to Vicodin and Percocet for three years, going so far as stealing from her own international aid outfit. Reason Online,

Haughee's appeals all are denied  -  Jul 2, 2008
...accuser was under the influence of at least 26 drugs daily for her conditions, including Xoloft, Wellbutrin, Xanax, Oxycodin, Percocet and Thorazine. Gary Post Tribune,

12 sought in area drug roundup  -  Jul 2, 2008
Most of the drug purchases made during the investigation involved sales of Methadone, Percocet or marijuana. Law enforcement officers from the Menifee Morehead News,

Two arrested after drug raid in Walpole  -  Jun 30, 2008
Luciano was also charged with illegal possession of Percocet. Executing a search warrant for the Taft Street home, officers found more than 100 syringes, Daily News Transcript,

Man Pleads Guilty to March Drug Deal  -  Jul 1, 2008
Carl Hendershot originally pleaded not guilty to the two counts of selling percocet in March. Tuesday, he reached a plea agreement with the State and WTAP-TV,

Burkesville Dentist Sentenced for Distributing Painkillers  -  Jun 30, 2008
This past December, Stephenson was found guilty of prescribing thousands of hydrocodone and percocet pills for no medical reason. WBKO,

Search uncovers $3000 of drugs  -  Jun 30, 2008
Cocaine, morphine and Percocet were among the narcotics, police said they found. Simon Barnes, 43, of 26 1/2 Wallace Terr., and Michelle Collins, 39, Sault Star,

Army's battle: Mental illness  -  Jun 23, 2008
On the day before he was to ship out in May 2007, he took a dozen Percocet painkillers, washed down with more than a liter of vodka. Chicago Tribune,

Windsor doctor facing drug charges released on bail  -  Jun 23, 2008
...and 80 milligram strengths, one count of possession of Percocet and one count of possession of hydromorphone, all for the purpose of trafficking. Canada.com,

District Court  -  Jun 26, 2008
Caron reportedly said that nine or 10 doses of percocet, seven doses of oxycontin and 10 to 15 doses of valium were missing. Bennington Banner,

Arrest made in Rite Aid burglary  -  Jul 2, 2008
On June 26, Dean was arrested for retail theft at Walmart and was allegedly found to be in possession of Fentanyl, Oxycontin, Methadone and Percocet, Towanda Daily Review,

Suboxone provides promising treatment for prescription addicts  -  Jun 28, 2008
Duley said some of the center's suboxone clients have Percocet "handed to them like candy for every little ache and pain -- it's a culture of doctors not Frederick News Post (subscription),

New hope for people addicted to opioids  -  Jun 26, 2008
For half of those addicted, Hilliard said, the addiction started when they were prescribed a painkiller, such as Percocet, Vicodin, OxyContin or Tylenol Chambersburg Public Opinion,

Former Swampscott police officer pleads guilty to drug distribution  -  Jun 12, 2008
The government alleged that during this five-year period, Wrenn distributed Percocet or Vicodin pills on approximately 20 occasions. Swampscott Reporter,

Open phone line helps nab drug store robber  -  Jun 16, 2008
Charbonneau said a man told the druggist at the Rite-Aid on Mammoth Road that he had a weapon and demanded methadone and the pain-killer, Percocet. Boston Herald,

FedEx employee admits theft  -  Jun 27, 2008
Stolen were four packages containing the prescription pain killer Percocet, a watch, an iPOD and a cell phone. When confronted, Kush admitted his wrongdoing Allentown Morning Call,

Police: Robber at Tamaqua pharmacy sought narcotic  -  Jun 27, 2008
The news release did not indicate the brand of pills, but oxycodone is found in OxyContin, Percocet, Percodan and Tylox. Oxycodone, especially in the form Allentown Morning Call,

How best to treat chronic pain? The jury is still out  -  Jun 6, 2008
Among the approaches to pain management studied were those relying on the prescription of opioids (drugs such as morphine, Percocet and Vicodin), surgery, Hindu,

FedEx thief lucky he didn't take shoes during stealing spree  -  Jun 27, 2008
...in the 100 block of North Commerce Way. Kush stole four bottles of Percocet, a pink Coach watch, a Motorola Razr phone and an iPod, all valued at $1691. PennLive.com,

Arrest Reports  -  Jun 25, 2008
Possession (Percocet ) Jackie Renee Ledbetter, 28, of 3709 Monte Vallo Manor in Fayetteville was arrested June 21 on a felony charges of possession of a Northwest Arkansas Times,

‘Wall-E’ Is a Masterpiece for the Ages  -  Jun 26, 2008
So here are notes, only partially addled by Percocet, for a larger essay. The thing is, first of all, a masterpiece. It’s one for the ages, New York Magazine,

12 Sought In Menifee Drug Roundup  -  Jun 27, 2008
Most of the drug purchases made during the investigation involved sales of Methadone, Percocet or marijuana. Law enforcement officers from the Menifee WYMT,

Warren doctor gets prison for drug distribution  -  Jun 17, 2008
...a 2006 indictment against Ognen for distributing more than 2.6 million doses of OxyContin, Percocet, and generic painkillers while practicing in Toledo. Detroit Free Press,

No clear answers for treating chronic pain  -  Jun 9, 2008
None of the clinical trials on opioid pain-relievers, such as morphine, Percocet and Vicodin, lasted longer than four months, even though most people with Los Angeles Times,

Kids and drugs  -  Jun 21, 2008
They are using a wide-range of drugs, such as marijuana, ecstasy, Special K, Percocet and Oxycontin. Ecstasy is a stimulant that can produce feelings of Sudbury Star,

Guilty plea expected from former Swampscott cop  -  Jun 7, 2008
The criminal complaint alleges Wrenn purchased Percocet pills, which are a form of oxycodone, over a period of months beginning in the fall of 2006. The Daily Item of Lynn,

Ex-cop expected to plead guilty in drug case  -  Jun 6, 2008
Wrenn was originally arrested March 13 outside a Lynn restaurant, where he had allegedly just accepted a package of Percocet pills from someone who was The Salem News,

Athens Township: Police make arrest in Rite Aid burglary  -  Jun 30, 2008
Brown and the juvenile accomplice then allegedly stole $23412.93 worth of prescription medications, such as fentanyl, oxycontin, hydrocondone, percocet, Morning Times,

Teens say they lied to police after fatal crash  -  Jun 3, 2008
Kropidlowski, who was 21 at the time, is accused of buying beer for Schultz, 16, Sanicola, then 17, and Samantha Guyette, then 16, and giving them Percocet, Milwaukee Journal Sentinel,

Drug cases move to court  -  Jun 20, 2008
By Jaime North DANVILLE -- An alleged drug dealer -- who police said tried to pass generic pain medicine off as Percocet, a prescription narcotic -- will Danville News,

Two Eastham teens arrested in Dennis  -  Jun 12, 2008
Andrew Keith, 17, of 100 Bayside Dr., Eastham, is charged with possession of controlled substances, Class B percocet and Class D marijuana, possession of a Wicked Local Dennis,

My husband got ‘friendly' with an ice pack, while I cried in the ...  -  Jun 23, 2008
It may be an easy Laparoscopic snip, but you can't take a Percocet for the emotional stuff. This is an original post from the New York City Moms Blog, Centre Daily Times,

Who Killed Jim Cannon?  -  Jul 2, 2008
...in Belle Meade and Green Hills to fill multiple prescriptions for Percocet and Oxycontin to squelch pain for back problems Jim said she never had. Nashville Scene,

Sheriff's office and police reports  -  Jun 20, 2008
A resident in the 60000 section of County Road 9, Newcomerstown, reported the theft of prescription medicine Percocet. A resident in the 200 block of North Coshocton Tribune,

Doctor suspends license over Rx-for-cash charges  -  Jun 11, 2008
The complaint said the doctor then told the officer to "give me $100 so I sign the prescription" for Percocet. The detective handed over $100 and the doctor The Star-Ledger - NJ.com,

Nurse Charged With Stealing Pills From Nursing Home  -  Jun 19, 2008
Court documents say Lori Camp stole 19 Percocet pills from patients at Meadowbrook Care Center on Montgomery Road near I-275. She was arrested, charged with Kentucky Post,

Fairfield dentist sentenced to prison  -  Jun 10, 2008
According to testimony, Dengelegi illegally wrote hundreds of prescriptions for OxyContin and Percocet for a drug addict he met at a gym, as well as friends Connecticut Post,

Cindy McCain Is Addicted To Prescription Drugs  -  Jun 20, 2008
Supposedly, she started taking Vicodin and Percocet pain killers after an operation in 1989, and cannot function without 10 to 15 pills a day. Javno.hr,

Being the change we want to see: Let's not trash Cindy McCain over ...  -  Jun 20, 2008
To deal with the resulting pain, she started using--then misusing--Percocet and Vicodin. Like many others, she became dependent. She stole some medication, Huffington Post,

Man indicted for attempted kidnapping  -  Jul 2, 2008
James Matthew Gregory Thall, 33, of 2432-220 Berryville Pike, Winchester on four counts of prescription drug fraud for Lortab and Percocet between Feb. Northern Virginia Daily,

Curtis Wrote Painkiller Addiction Letter To Sister  -  Jun 17, 2008
I have found and taken many of your Percocet and Vicodin.'" Curtis reveals her sister Kelly was prescribed painkillers for a broken bone - and the letter Showbiz Spy,

Baron Davis, Movie Producer  -  Jun 30, 2008
Los Angeles premiers tend to be gratuitous -- even for movies that warrant nothing more than a starting pistol and some Percocet. ESPN

COURT SENTENCING: April-May convictions  -  Jun 6, 2008
Curtis Weatherford -- consecutive terms for: possession of methamphetamine, 12-34 months; possession of a controlled substance (Percocet), 12-34 months, Pahrump Valley Times,

Tribal official charged with drug misconduct  -  Jun 12, 2008
A federal search warrant revealed 49 Percocet pills and 50 Hydrocodone pills in unmarked bottles that did not contain a prescription. Fort Mills Times,

UNC commit McAdoo arrested  -  Jun 17, 2008
The charge stems from a post-graduation party where the 6-foot-2, 285-pound defensive tackle allegedly sold Percocet. Logging in 59 tackles, 20 TFL’s and 13 RealFootball365.com,

Brand Names/Synonyms:
Percocet is also known by the following brand names and/or synonymsCodeinone, Dihydrohydroxy-; Combunox; Dea No. 9143; Dihydrohydroxycodeinone; Dihydrohydroxycondeinone; Dihydrone; Dihydroxycodeinone; Dinarkon; Diphydrone; ENDOCET; ENDODAN; Endone; Eubine; Eubine [France]; Eucodal; Eucodalum; Eukodal; Eutagen; HSDB 3142; Ossicodone [Dcit]; Oxanest; Oxicodona [Inn-Spanish]; Oxicon; Oxicone; Oxikon; Oxycet; Oxycodeinone; Oxycodon; Oxycodone; Oxycodone Hcl; Oxycodone Hydrochloride; Oxycodone [Usan:Ban:Inn]; Oxycodonum [Inn-Latin]; Oxycon; Oxycontin; PERCOCET; Pancodine; Percobarb; Percocet; Percodan; Roxicet; Roxicodone; Roxilox; Supendol [Canada]; Tecodin; Tekodin; Thecodine; Thekodin; Tylox

Drug Category:
Percocet is categorized under the following by the FDA: Narcotics; Antitussives; Analgesics, Opioid; Opiate Agonists; ATC:N02AA05

Dosage Forms:
Tablet; Suppository

Absorption:
well absorbed from OxyContin� tablets with an oral bioavailability of 60% to 87%

Interactions:
Interactions for Oxycodone:

The CNS depressant effects of oxycodone hydrochloride may be additive with that of other CNS depressants..

Chemical IUPAC Name:
4, 5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one

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