Percocet

This page contains recent news articles, when available, and an overview of Percocet but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Percocet
(when available)

Pharmacology and use:
Oxycodone, a semisynthetic opiate agonist derived from the opioid alkaloid, thebaine, is similar to other phenanthrene derivatives such as hydrocodone and morphine. Oxycodone is available in combination with aspirin or acetaminophen to control pain and restless leg and Tourette syndromes. For the treatment of diarrhoea, pulmonary oedema; For the relief of moderate to moderately severe pain

Mechanism Of Action:
Oxycodone acts as a weak agonist at OP1, OP2, and OP3 opiate receptors within the central nervous system (CNS). Oxycodone primarily affects OP3 receptors, which are coupled with G-protein receptors and function as modulators, both positive and negative, of synaptic transmission via G-proteins that activate effector proteins. Binding of the opiate stimulates the exchange of GTP for GDP on the G-protein complex. As the effector system is adenylate cyclase and cAMP located at the inner surface of the plasma membrane, opioids decrease intracellular cAMP by inhibiting adenylate cyclase. Subsequently, the release of nociceptive neurotransmitters such as substance P, GABA, dopamine, acetylcholine, and noradrenaline is inhibited. Opioids such as Oxycodone also inhibit the release of vasopressin, somatostatin, insulin, and glucagon. Opioids close N-type voltage-operated calcium channels (OP2-receptor agonist) and open calcium-dependent inwardly rectifying potassium channels (OP3 and OP1 receptor agonist). This results in hyperpolarization and reduced neuronal excitability.

News Articles on Oxycodone

Robberies put spotlight on drug thefts  -  20 Apr 2009
The other suspect jumped over the counter and grabbed more than 1000 tablets of Percocet and Oxycontin, and stuffed them into his cargo-style pants. WRAL.com

Prestonsburg Man Arrested on Drug Charges  -  20 Apr 2009
Police say Warick had in his possession 114 Roxicet tablets, 11 1/2 Percocet tablets, 32 Soma tablets, and a dozen Xanax bars. They also confiscated nearly WSAZ-TV

QRxPharma Successfully Completes Comparative Study for Dual-Opioid ...  -  20 Apr 2009
Additional studies evaluating MoxDuo(TM) IR versus Percocet(R) in patients with joint replacement surgery are underway, with results expected in Q3 of 2009. PR Newswire (press release)

Woman allegedly buys drugs in front of police  -  20 Apr 2009
Sherry Annette Carey, 26, of 232 Shane Dr., Mount Holly, allegedly purchased 16 doses of percocet from a man in front of a Mount Holly police sergeant. Gaston Gazette

Edison drug store burglarized for second time in three weeks  -  20 Apr 2009
Once inside, the masked burglar stole several types of drugs including Oxycodone, Percocet and Xanax. Police did not immediately have a dollar value of the New Brunswick Home News Tribune

Police arrest four men for trafficking in Oxycontin  -  20 Apr 2009
...on charges of possession of class B substance-Percocet, possession of class B substance-Oxycontin, possession of class B substance-Oxycontin with intent Lakeville Call

Ohio to share prescription data in bid to cut climbing rate of ...  -  ‎Apr 15, 2009‎
A growing number of states have authorized these monitoring programs to catch people "doctor shopping" for narcotic painkillers such as Vicodin and Percocet The Plain Dealer - cleveland.com

Post-Bulletin, Rochester MN  -  ‎Apr 16, 2009‎
In Kreye's home, they found Dilaudid, a Fentanyl patch, half an Oxycontin, 29 morphine sulfate tablets, a Percocet, two Lorazapam and 201/2 Darvocet. Post-Bulletin

Calvert County Sheriff's Reports  -  ‎Apr 14, 2009‎
Found inside the home were Percocet and Valium pills with a combined street value of $540 and almost 8 grams of marijuana with a $50 street value. Southern Maryland Online

Prescription drug drop-off sites announced  -  ‎Apr 17, 2009‎
Drugs such as OxyContin, oxycodone, hydrocodone, morphine, codeine, Percocet, Darvocet, Vicodin and Lortab have all been linked to opiate addiction. Janesville Gazette

Driver convicted in fatal Vegas bus stop crash  -  ‎Mar 31, 2009‎
He told police after the crash that he took Percocet and Valium the night before to relieve pain from an old back injury. He faces 25 years to life in San Jose Mercury News

Shortage of pain-relief drug hits region  -  ‎Apr 13, 2009‎
Because of the shortage, Dr. Conermann said, his institute has been prescribing Percocet, an analgesic that combines oxycodone and the over-the-counter pain Pittsburgh Post Gazette

Two men rob Raeford pharmacy of painkillers  -  ‎Apr 17, 2009‎
The man with the rifle watched the workers and customers while the second man jumped the counter into the pharmacy and demanded OxyContin and Percocet, FayObserver.com

Prescription drug-related fraud arrests highlight Bridgeton crime log  -  ‎Apr 16, 2009‎
The prescriptions were for Percocet pills, and were dropped off at the pharmacy at the Millville Target and at Woodruff's Drugs, located on Laurel Street, NJ.com

Medical procedure makes East Meadow man taller  -  ‎Apr 19, 2009‎
Roth has a prescription for the potent painkiller Percocet, which he takes every six hours. Roth must be attentive to keeping the sites clean to avoid Newsday

Mandarich Was 'Not Sober' in Green Bay  -  ‎Apr 17, 2009‎
Stadol, Fiorinal #3, Valium, Percodan, Percocet, Vicodin. The shots eventually became pills because they were easier to come by, and sometimes the pills FanHouse

Tackling top teen problem - prescription drugs  -  ‎Apr 11, 2009‎
Many people ages 11 to 18 routinely take pills such as Vicodin, Percocet, Xanax, Klonopin, Adderal, Concerta, Ritalin or generic knockoffs of the same. North Platte Bulletin

Phila. doctor indicted on drug-distribution charges  -  ‎Apr 9, 2009‎
...office specializing in physical therapy and rehabilitation, and pay $100 for prescriptions for the painkiller Percocet and the antianxiety drug Xanax. Philadelphia Inquirer

Weapons, drugs seized from Commack home  -  ‎Apr 3, 2009‎
More arrests are expected. Detectives found marijuana valued at $5000 and large quantities of Percocet and Vicodin pills, police said. Newsday

Brockton pediatrician suspended from practice  -  ‎Apr 2, 2009‎
For instance, Recchio is accused of overprescribing drugs to a 17-year-old girl for several years, giving her nine different drugs, including Percocet, Wicked Local Brockton

Defendants, put your trust in . . . judge  -  ‎Apr 15, 2009‎
Two Xanax and some white pills (which couldn't have been Percocet or I'd have taken them already) found in the car. Only God knows how they got there. Tucson Citizen

Asheville woman charged with forging prescription  -  ‎Apr 15, 2009‎
ASHEVILLE – Buncombe County sheriff’s deputies say an Asheville woman tried to use a forged prescription to buy Percocet from a drug store. Asheville Citizen-Times

THE TEST: MONDAY  -  ‎Apr 4, 2009‎
The patient was in deep pain - after a medical resident had replaced morphine with less potent Percocet. "Of course, Percocet wasn't working," Salemmo said. Newsday

Ken Lawson Sentenced to Two Years  -  ‎Apr 8, 2009‎
Lawson pleaded guilty to masterminding a scheme to get prescription drugs like Oxycontin and Percocet. Court documents say Lawson received fraudulent WKRC TV Cincinnati

No jail time for driver in 2006 fatal Yonkers crash  -  ‎Apr 2, 2009‎
Authorities said she had five times the recommended dosage of Percocet in her bloodstream at the time of the crash. She had her young son in the car with Lower Hudson Journal news

Doctor Admits Illegally Dispensing Oxycodone  -  ‎Mar 31, 2009‎
Specifically, Agrawal admitted that on four occasions between January 2008 and June 2008, he sold prescriptions for Percocet to an individual, Imperial Valley News

Prison, Probation Or Both For High Profile Attorney?  -  ‎Apr 8, 2009‎
...who would then give them to him. Lawson says he became addicted to the painkillers Oxycontin and Percocet after hurting himself lifting weights. WCPO

New Bedford woman arraigned on drug charges  -  ‎Apr 3, 2009‎
On Thursday, police arrested Taylor's girlfriend, Gemma Tobalyas, 58, at 68 Eugenia St. Detectives seized 63 grams of crack cocaine, $1746 in cash, Percocet South Coast Today

Signup for medical marijuana usage begins Monday  -  ‎Apr 4, 2009‎
Morphine and fentanyl had too many negative side effects and all of the drugs, including the Percocet he takes now, are highly addictive. Kalamazoo Gazette - MLive.com

$1400 in drugs seized  -  ‎Apr 16, 2009‎
Officers seized four ounces of marijuana, two OxyContin pills and 20 percocet pills. Adam Reynolds, 29, is charged with two counts possession of a Peterborough Examiner

Two Young Callaway Girls Busted after Attempting To Sell Oxycodone ...  -  ‎Apr 3, 2009‎
Oxycodone is the opioid pain medication found in Percocet, Percodan, and OxyContin. Broward County currently leads the nation in the amount of Oxycodone WJHG-TV

Prescription drugs top Oregon overdose stats  -  ‎Mar 31, 2009‎
Pharmacists are noticing that pain patients who once were prescribed oxycodone, Percocet or morphine are converting to methadone because it's much cheaper The Oregonian - OregonLive.com

Canton Official Had Pills, Not Pot  -  ‎Apr 2, 2009‎
Bennett also was charged with possession of narcotics for having one Percocet and failure to keep prescription drugs in their original container because all Hartford Courant

OxyContin Addiction Treatment Evolves To Stem the Tide  -  ‎Apr 8, 2009‎
..."the deaths that we are reading about in the news are sometimes from a prescription drug (like OxyContin, Percocet, or Vicodin), but more commonly from TransWorldNews (press release)

Pills stolen from Glendora pharmacies  -  ‎Apr 9, 2009‎
GLENDORA - Two pharmacies were struck by burglars who grabbed bottles of Percocet and Tylenol-3 early Thursday, police said. The first pharmacy was hit San Gabriel Valley Tribune

Man charged in Carlisle chase identified  -  ‎Mar 31, 2009‎
...was injured when the van rolled over after being rammed. Police said cocaine, heroin, marijuana, Ecstasy and Percocet were found in the van after the crash. PennLive.com

Forging a new alliance  -  ‎Apr 7, 2009‎
She was prescribed Percocet, a mix of the semi-synthetic opiate oxycodone and acetaminophen, the painkiller used in Tylenol. Northfield News (subscription)

Matt Lauer returns to chorus of jokes  -  ‎Mar 29, 2009‎
..."It's the same guy who asked me for four Percocet (painkiller) 15 minutes ago," he said. NBC also invited Tony Kornheiser of ESPN's "Pardon the Interruption Waterloo Cedar Falls Courier

Thousands Of Dollars Worth Of Drugs Confiscate By New Britain Police  -  ‎Mar 31, 2009‎
They found five pounds of high-grade marijuana in the apartment, 6.2 grams of cocaine, 23 packets of heroin, 564 Vicodin pills and 51 Percocet pills, Hartford Courant

Lynn police charge two for phony 911 calls  -  ‎Apr 8, 2009‎
Item records show a man named OC Payne III, 21, who lives at 95 Woodman St., was arrested in June after selling percocet pills to an undercover State Police Daily Item

Canton Board To Meet With Parks And Recreation Director After DUI ...  -  ‎Mar 31, 2009‎
He also was charged with possession of less than 4 ounces of marijuana, possession of narcotics, which police said was Percocet, and failure to keep a Hartford Courant

Aggravated battery, prescription drug theft reported  -  ‎Apr 7, 2009‎
He then allegedly proceeded to take Hydromorphone, Percocet and Diloted pills from the residence. The incident occurred at 780 Allen Road around 6 pm Monday Kansas State Collegian

Tip Leads Lower Police to Nab North Cape May Man  -  ‎Mar 30, 2009‎
By Herald Staff NORTH CAPE MAY — A North Cape May man was arrested Friday, March 27 after police allege he was found in possession of 20 Percocet pills Cape May County Herald

Gunman Robs Pharmacy  -  ‎Apr 8, 2009‎
The gunman demanded Oxycontin and Percocet. A worker ran to a business next door for help. "A lady that works at the pharmacy came over at a quarter after WNEP-TV

Never argue with your girlfriend if you're a wanted man (and she ...  -  ‎Apr 6, 2009‎
Breeswine and arrested him without incident. Police then searched Breeswine and found him with drug paraphernalia and Percocet pills not registered to him. Pocono Record

Woman Arrested for Prescription Fraud  -  ‎Mar 31, 2009‎
Williams was charged with possession of oxycodone, possession of Percocet, two counts of possession of drug paraphernalia, attempt to obtain CDS by uttering WBOC TV 16

Brand Names/Synonyms:
Percocet is also known by the following brand names and/or synonymsCodeinone, Dihydrohydroxy-; Combunox; Dea No. 9143; Dihydrohydroxycodeinone; Dihydrohydroxycondeinone; Dihydrone; Dihydroxycodeinone; Dinarkon; Diphydrone; ENDOCET; ENDODAN; Endone; Eubine; Eubine [France]; Eucodal; Eucodalum; Eukodal; Eutagen; HSDB 3142; Ossicodone [Dcit]; Oxanest; Oxicodona [Inn-Spanish]; Oxicon; Oxicone; Oxikon; Oxycet; Oxycodeinone; Oxycodon; Oxycodone; Oxycodone Hcl; Oxycodone Hydrochloride; Oxycodone [Usan:Ban:Inn]; Oxycodonum [Inn-Latin]; Oxycon; Oxycontin; PERCOCET; Pancodine; Percobarb; Percocet; Percodan; Roxicet; Roxicodone; Roxilox; Supendol [Canada]; Tecodin; Tekodin; Thecodine; Thekodin; Tylox

Drug Category:
Percocet is categorized under the following by the FDA: Narcotics; Antitussives; Analgesics, Opioid; Opiate Agonists; ATC:N02AA05

Dosage Forms:
Tablet; Suppository

Absorption:
well absorbed from OxyContin® tablets with an oral bioavailability of 60% to 87%

Interactions:
Interactions for Oxycodone:

The CNS depressant effects of oxycodone hydrochloride may be additive with that of other CNS depressants..





Chemical IUPAC Name:
4, 5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one

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