Norpramin

This page contains recent news articles, when available, and an overview of Norpramin but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Norpramin
(when available)

Pharmacology and use:
Protriptyline is a tricyclic antidepressant. It was thought that tricylic antidepressants work by inhibiting the re-uptake of the neurotransmitters norepinephrine and serotonin by nerve cells. However, this response occurs immediately, yet mood does not lift for around two weeks. It is now thought that changes occur in receptor sensitivity in the cerebral cortex and hippocampus. The hippocampus is part of the limbic system, a part of the brain involved in emotions. Presynaptic receptors are affected: a1 and b1 receptors are sensitized, a2 receptors are desensitised (leading to increased noradrenaline production). Tricyclics are also known as effective analgesics for different types of pain, especially neuropathic or neuralgic pain. A precise mechanism for their analgesic action is unknown, but it is thought that they modulate anti-pain opioid systems in the CNS via an indirect serotonergic route. They are also effective in migraine prophylaxis, but not in abortion of acute migraine attack. The mechanism of their anti-migraine action is also thought to be serotonergic. For the treatment of depression and obsessive-compulsive disorders

Mechanism Of Action:
Protriptyline acts by decreasing the reuptake of norepinephrine and serotonin (5-HT).

News Articles on Protriptyline

Help Possible For People Obsessed With Imaginary Physical Flaws  -  Jan 21, 2009
In the other included drug study, symptom severity declined significantly with clomipramine (Anafranil) treatment compared to desipramine (Norpramin); eMaxHealth.com,

ИпохондриÑ? – тоже болезнь  -  Feb 3, 2009
Эффективны также трицикличеÑ?кие антидепреÑ?Ñ?анты, такие как clomipramine (Anafranil) и desipramine (Norpramin). Что каÑ?аетÑ?Ñ? пÑ?ихотерапии, то 12 недель медицинÑ?кий портал Здоровье Украины,

Photosensitive medicines listed  -  Aug 23, 2007
Antidepressants: amitriptyline (Elavil); amoxapine (Asendin); bupropion (Wellbutrin); citalopram (Celexa); clomipramine (Anafranil); desipramine (Norpramin) Biloxi Sun Herald,

Antidepressant Gatekeeper  -  Aug 12, 2007
Since the 1950s, TCAs such as desipramine (Norpramin and Pertofrane) have been prescribed to treat symptoms of depression. They prevent reuptake of Chemical & Engineering News

International drugs have same name, but different medications  -  Jul 12, 2007
KOMO,In the US, Norpramin is an antidepressant. In Spain, Norpramin is an ulcer medicine. Vivelle, a hormone treatment for menopause in this country,

Link Between Antidepressants and Bone Loss Found  -  Jun 28, 2007
Drug Discovery & Development,TCAs include such drugs as amitriptyline (Elavil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Tofranil) and nortriptyline (Pamelor).

Buy cialis online! Cheap prices! Please CHOOSE  -  Jun 14, 2007
Biznes blog money.pl,...to treat diabetes, such as amitriptyline Elavil, Etrafon, amoxapine Ascendin, clomipramine Anafranil, protriptyline Vivactil, or desipramine Norpramin.

Antidepressants linked to suicide risk in young adults  -  May 5, 2007
Food Consumer,Ludiomil (maprotiline), Marplan (isocarboxazid), Nardil (phenelzine sulfate), nefazodone HCl, Norpramin (desipramine HCl), Pamelor (nortriptyline),

FDA - all antidepressants need new warning labels  -  May 3, 2007
News-Medical.net,Elavil, Effexor, Emsam, Etrafon, fluvoxamine maleate, Lexapro, Limbitrol, Ludiomil, Marplan, Nardil, nefazodone HCl, Norpramin, Pamelor, Parnate, Paxil,

New Warning on Effexor Overdoses  Oct 25, 2006
...antidepressants. SSRIs include Prozac, Paxil, Celexa, and Zoloft. Tricyclic antidepressants include Elavil and Norpramin. News about ... -WebMD Addressing Psychiatric Comorbidities in Patients With Epilepsy  Oct 26, 2006
Other interventions include atomoxetine (Strattera) and tricyclic antidepressants such as imipramine (Tofranil) and desipramine (Norpramin, Pertofrane). ... -Psychiatric Times, Update: Diet Pill Acomplia May Prevent Weight Gain Common to ...  Jul 10, 2006
...mice and rats that were given the SSRI anti-depressant fluoxetine (Prozac) as well as the older tricyclic antidepressant desipramine (Norpramin or Pertofrane). ... -Acomplia Report

Shingles and Chickenpox (Varicella-Zoster Virus)  Jun 23, 2006
PHN. Nortriptyline (Pamelor, Aventyl), amitriptyline (Elavil, Endep), and desipramine (Norpramin) are standard agents. According ... -About - News & Issues



Antidepressants May Reduce Colorectal Cancer Risk  Mar 9, 2006
Tricyclic antidepressants include Tofranil® (imipramine), Elavil® (amitriptyline), Norpramin® (desipramine), and Aventyl®, or Pamelor® (nortriptyline). ... - Cancer Consultants



Treating ADD With Medication 07 Mar 2006
...known as Stratera; buproprion, known as Wellbutrin; clonidine, known as Catapres; imipramine, known as Tofranil; and desipramine, known as Norpramin. ... - DailyIndia.com,

US and Foreign Drug Names  Feb 22, 2006
In the United States, Norpramin is the brand name for an antidepressive drug containing desipramine, but in Spain, Norpramin is the name of a drug that ... - Journal of American Medical Association (subscription),

When Abroad, Beware of Drug Name Confusion Feb 8, 2006
For example, in the United States, Norpramin is the brand name of the drug desipramine, which is prescribed for depression. If you ... - Diabetes Self Management

Early response to anti-bulimia drug a good sign  Feb 10, 2006
Health) - Women with the binge and purge eating disorder, bulimia nervosa, who respond to treatment with the antidepressant desipramine (Norpramin) within the ... - Reuters.uk,

When Abroad, Beware of Drug Name Confusion  Feb 8, 2006
For example, in the United States, Norpramin is the brand name of the drug desipramine, which is prescribed for depression. If you ... - Diabetes Self Management

Leptin Acts as Rodent Antidepressant  Jan 16, 2006
They were compared with control rats (injected with saline) and with rats who were treated with Norpramin (desipramine), a medication used as an antidepressant ... - MedPage Today

FDA Cautions Consumers Against Filling US Prescriptions Abroad  Jan 12, 2006
In the United States, "Norpramin" is the brand name for an anti-depression drug containing desipramine but, in Spain, the same brand name, "Norpramin," is used ... - Community Dispatch

FDA warns against buying prescription drugs on the net or overseas  Jan 17, 2006
..."Norpramin" in the US is the brand name for an anti-depression drug containing desipramine but, in Spain, the same brand name, "Norpramin," is a drug that ... - News-Medical.net

US warns of brand errors in imported drugs  Jan 12, 2006
...names cited in the FDA warning are: Aldactone, Alphadine, Antagon, Calan, Cervidil, Cloderm, Diasorb, Dilacor, Flomax, Hexalen, Naqua, Norpramin, Rubex, Urex ... - International Herald Tribune

Brand Names/Synonyms:
Norpramin is also known by the following brand names and/or synonymsAmimetilina; Anafranil; Apo-Amitriptyline; Apo-Imipramine; Apo-Trimip; Asendin; Aventyl; Elavil; Impril; Levate; MK 240; Norpramin; Novo-Doxepin; Novo-Tripramine; Novopramine; Novotriptyn; Pertofrane; Protriptyline; Protryptyline; Rhotrimine; Sinequan; Surmontil; Tofranil; Triadapin 5; Triptil; Vivactil

Drug Category:
Norpramin is categorized under the following by the FDA: Antidepressants; Norepinephrine-Reuptake Inhibitors; ATC:N06AA11

Dosage Forms:
TABLET

Absorption:
Not Available

Interactions:
DRUG INTERACTIONS If Protriptyline is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Patient should check with doctor before combining Protriptyline with the following: Antidepressants that boost serotonin, including Paxil, Prozac, and Zoloft Antipsychotic medications such as Mellaril and chlopromazine Barbiturates such as Nembutal and Seconal Certain blood pressure medications such as guanethidine Cimetidine (Tagamet) Decongestants such as Sudafed Drugs that quell spasms, such as Donnatal and Levsin Epinephrine (EpiPen) Flecainide (Tambocor) Narcotic painkillers such as Percodan and Vicodin Norepinephrine Other antidepressants such as Elavil and Tofranil Propafenone (Rythmol) Quinidine Tramadol (Ultram) Tranquilizers and sleep aids such as Halcion, Valium, and Xanax Protriptyline must never be combined with monoamine inhibitors such as Nardil and Parnate.



Chemical IUPAC Name:
Not Available

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