Methylin

This page contains recent news articles, when available, and an overview of Methylin but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Methylin
(when available)

Pharmacology and use:
Methylphenidate, a central nervous system stimulant chemically similar to the amphetamines, is used to treat narcolepsy, attention-deficit hyperactivity disorder (ADHD) in children, post-stroke depression or other depressive disorders. Children with attention deficit disorders

Mechanism Of Action:
Methylphenidate blocks dopamine uptake in central adrenergic neurons by blocking dopamine transport or carrier proteins. Methylphenidate acts at the brain stem arousal system and the cerebral cortex and causes increased sympathomimetic activity in the central nervous system. Alteration of serotonergic pathways via changes in dopamine transport may result.

News Articles on Methylphenidate

Sciele Pharma Inc. Q2 2008 Earnings Call Transcript  -  Jul 30, 2008
...which include Prenate DHA, Prandin, Fenoglide, Orapred ODT, Allegra or suspension in ODT, Twinject and Methylin. These seven new products accounted for Seeking Alpha,

Sciele Pharma, Inc. Reports Results for the Second Quarter of 2008  -  Jul 30, 2008
Twinject and Methylin CT.� In the second quarter of 2008, gross margin as a percentage of sales was 86% compared with 87% in the second quarter of 2007. Business Wire (press release),

Sciele Pharma, Inc. Reports Results for the Second Quarter of 2008  -  Jul 30, 2008
Twinject and Methylin CT." In the second quarter of 2008, gross margin as a percentage of sales was 86% compared with 87% in the second quarter of 2007. Genetic Engineering News (press release),

Police seize 1000 pills, guns in raid  -  May 30, 2008
Members of the St. Clair County Sheriff Office Drug Task Force seized Vicodin, Darvocet, Lortab, Valium, Methylin and Xanax from the home in the 1600 block Port Huron Times Herald,

Cardiac Screening Recommended for Kids Taking Stimulants for ADHD  -  Apr 21, 2008
Some of the names under which these drugs are marketed include Adderall, Concerta, Cylert, Dexedrine, Focalin, Ritalin, Ritalin SR or LA, Methylin, U.S. News & World Report,

Sciele Pharma Inc. Q4 2007 Earnings Call Transcript  -  Mar 7, 2008
Net revenues for the company’s pediatric and other products, of which the key products include Orapred ODT, Methylin Oral Solution and Chewable Tablets and Seeking Alpha,

Sciele Pharma, Inc. Reports Results for Fourth Quarter and Year ...  -  Feb 27, 2008
...which include Orapred Orally Disintegrating Tablets (ODT) and Oral Suspension, Allegra Oral Suspension (OS), Methylin Chewable Tablets and Oral Solution FOXBusiness

Doctor’s conviction upheld in internet drug case  -  Nov 21, 2007
The indictment alleged that he illegally sold the stimulant Methylin, the narcotic preparation Hydrocodone, the controlled substance Nandralone and more EmpireStateNews.net,

Sciele Pharma, Inc. Reports Revenues and Earnings for the Third ...  -  Oct 30, 2007
Net revenues for the Company's Pediatric and other products, which include Orapred and Orapred ODT; Methylin Oral Solution and Methylin Chewable Tablets; Business Wire (press release),

Thiensville psychiatrist in court after manhunt: He and girlfriend ...  -  Oct 27, 2007
Steinhaus also was charged in Wyoming with 27 misdemeanor counts of illegally prescribing more than 3000 tablets of Methylin and methylphenidate Trading Markets (press release),

Woman, 23, pleads innocent to drugs  -  Oct 23, 2007
By Patricia Breakey Amanda M. Young, 23, of Gilboa, pleaded innocent to third-degree criminal possession of a controlled substance _ methylin, fourth-degree Oneonta Daily Star,

World Experts Demand End to Child Drugging in the US - Part I  -  Oct 25, 2007
...to inform patients about the adverse effects of Adderall, Concerta, Daytrana, Desoxyn, Dexedrine, Focalin, Metadate CD, Methylin, Ritalin and Strattera. Lawyers and Settlements,

For the record  -  Oct 14, 2007
Jean R. Nelson, 22, 2409 10th St., Two Rivers, possess methylin, $323.50, six months license suspension. Kheng Yang, 23, 1411 S. 19th St., Manitowoc, Herald Times Reporter,

Methylin chewable ADHD drug  -  Sep 5, 2007
The Food and Drug Administration approved Alliant's Methylin Chewable Tablets and Methylin Oral Solution and the pediatric specialty pharmaceutical company SpiritIndia,

Hospital Protocol For Patient, Staff, Visitor Exposure  -  Jul 3, 2007
Pittsburgh Channel.com,Everyone carries microbes on their skin or in their lungs, which could be the common cold, tuberculosis or worse, methylin resistant staph aureus.

Breaking glass nets arrests in Geneva  -  May 4, 2007
Ashtabula Star-Beacon,During the search the officers found several 10 milligram pills of the drug Methylin, which is also known as Ritalin, in a plastic bag in Pasko's pocket,

Sciele Pharma to Acquire Alliant Pharmaceuticals, a Pediatric ...  -  Apr 25, 2007
PipelineReview.com (press release),Methylin(R) Oral Solution and Methylin(R) Chewable Tablets for attention deficit hyperactivity disorder (ADHD); Lindane for head lice and scabies;

Alliant to become part of Sciele  -  Apr 25, 2007
San Antonio Business Journal,Alliant's products include Orapred and Orapred ODT for asthma; Allegra Oral Suspension for allergies; Methylin Oral Solution and Methylin Chewable Tablets

Capture ends 2-week chase  -  Jan 14, 2007
Milwaukee Journal Sentinel (subscription),28 with 27 misdemeanor counts of illegally prescribing more than 3000 tablets of Methylin and methylphenidate hydrochloride, which are closely related to

Third time is charm for psychiatrist and girlfriend on the lam  -  Jan 10, 2007
Gillette News Record,The prescriptions were for methylin and methylphenidate hydrochloride, which are generics for the attention deficit disorder drug Ritalin.

Methylin Oral Solution is Child Preferred  Oct 30, 2006
...a pediatric specialty pharmaceutical company, today announced preliminary results of the company's sponsored survey on Methylin Oral Solution. ... -Yahoo! News (press release) Help Meeting the Challenges of Parenthood and Poverty  Nov 6, 2006
...center. Aranza’s medication, Methylin, is working. “It’s amazing the difference; she can focus,â€? said Ms. Taveras. When ... -New York Times, ADHD treatment safe and effective for preschoolers  Oct 31, 2006
...children. Methylphenidate, a mild central nervous system stimulant, is sold as Ritalin, Methylin and under other trade names. It ... -Reuters.uk, County jail sentences served one day at a time  Oct 13, 2006
He opens a drawer stuffed with rattling bottles of Paxil, Trazadone, Hydrocodone, Methylin, Ritalin, Zoloft, Alprazolam, painkillers, sleep aids, anti ... -Daily Mining Gazette, Jury convicts Wakefield man on charges he delivered Ritalin  Aug 28, 2006
...tested one of the pills and was able to identify it as methylphenidate, the chemical name for a Schedule 2 controlled substance marketed as Ritalin and Methylin ... -Ironwood Daily Globe

Jury convicts Wakefield man on charges he delivered Ritalin  29 Aug 2006
...tested one of the pills and was able to identify it as methylphenidate, the chemical name for a Schedule 2 controlled substance marketed as Ritalin and Methylin ... -Ironwood Daily Globe



Studies on ADHD drugs get attention  Apr 4, 2006
The medications that caught the advisory board's attention are methylphenidates, which are sold as Ritalin, Concerta, Methylin and Metadate. ... - Jackson Clarion Ledger

Dr. Mona: ADHD Drug Warnings  Mar 22, 2006
The medications under the microscope are amphetamines like Dexedrine and Adderall, and methylphenidates like Concerta, Focalin, Metadate, Methylin and Ritalin. ... - CBS 11

Midday Business Report: Missouri employers avoid cut in tax credit  09 Feb 2006
...hypertension. The drugs include amphetamines, such as Adderall, and methylphenidates, sold as Ritalin, Concerta, Methylin and Metadate. ... - Kansas City Star

National news briefs  09 Feb 2006
...the drugs. which include amphetamines such as Adderall, and methylphenidates, sold as Ritalin, Concerta, Methylin and Metadate. - Concord Monitor

World brief  09 Feb 2006
...potential cardiovascular risks of the drugs, which include amphetamines such as Adderall, and methylphenidates, sold as Ritalin, Concerta, Methylin and Metadate ... - Salem News

ADHD Individual Drug Risk Studies To Be Considered By Drug Safety ...  Feb 8, 2006
...s Dexedrine and Dexedrine Spansules), methylphenidate (J&J’s Concerta, Novartis’ Ritalin, Ritalin SR, and Ritalin LA; Alliant’s Methylin and Methylin ER ... - FDA Advisory Committee

Brand Names/Synonyms:
Methylin is also known by the following brand names and/or synonyms4311/B Ciba; C 4311; CHEMBANK1663; Calocain; Centedein; Centedrin; Centedrine; Centredin; Concerta; Dea No. 1724; Focalin; Focalin Xr; HSDB 3126; METHYLPHEN; Meridil; Metadate; Metadate Cd; Metadate Er; Methyl Phenidyl Acetate; Methylin; Methylin Er; Methylofenidan; Methylphenidan; Methylphenidate; Methylphenidate Hcl; Methylphenidate Hydrochloride; Methylphenidatum [Inn-Latin]; Methylphenidylacetate Hydrochloride; Methypatch; Metilfenidat Hydrochloride; Metilfenidato [Inn-Spanish]; Metilfenidato [Italian]; Phenidylate; Plimasine; Pms-Methylphenidate; Riphenidate; Ritalin; Ritalin Hydrochloride; Ritalin La; Ritalin Sr; Ritalin-Sr; Ritaline; Ritcher Works

Drug Category:
Methylin is categorized under the following by the FDA: Adrenergic Agents; Dopamine Agents; Central Nervous System Agents; Anorexigenic Agents; Stimulants; ATC:N06BA04

Dosage Forms:
Tablets, SR tablets

Absorption:
readily absorbed in a biphasic manner. It reaches peak absorption at approximately two hours for the first phase and five hours for the second phase. bioavailability is low (approx. 30%)

Interactions:
-->Interactions for Methylphenidate:

Ritalin may decrease the hypotensive effect of guanethidine. Use cautiously with pressor agents.

Human pharmacologic studies have shown that Ritalin may inhibit the metabolism of coumarin anticoagulants, anticonvulsants (phenobarbital, diphenylhydantoin, primidone), phenylbutazone, and tricyclic drugs (imipramine, clomipramine, desipramine). Downward dosage adjustments of these drugs may be required when given concomitantly with Ritalin.

Serious adverse events have been reported in concomitant use with clonidine, although no causality for the combination has been established. The safety of using methylphenidate in combination with clonidine or other centrally acting alpha-2 agonists has not been systemically evaluated.

 




Chemical IUPAC Name:
methyl2-phenyl-2-(2-piperidyl)ethanoate

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