Metaxalone

This page contains recent news articles, when available, and an overview of Metaxalone but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Metaxalone (when available)

Pharmacology and use:
Metaxalone is a skeletal muscle relaxant indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. Metaxalone does not directly relax tense skeletal muscles in man. For the treatment of painful musculoskeletal conditions

Mechanism Of Action:
The mechanism of action of metaxalone in humans has not been established, but may be due to general central nervous system depression.

News Articles on Metaxalone

King Pharmaceuticals Reports Second Quarter 2009 Financial Results  -  ‎Aug 6, 2009‎
Net sales of SKELAXIN(R) (metaxalone) totaled $102 million during the second quarter of 2009, compared to $107 million during the same period of the prior FOXBusiness

Studies Find Factories Release Pharmaceuticals  -  ‎Apr 19, 2009‎
One drug, the muscle relaxant metaxalone, was measured in treated sewage at concentrations hundreds of times higher than the level at which federal ABC News

"제약공장 �??수�? �?�약품 성분 다량 �?�함"  -  ‎Apr 19, 2009‎
...특히 근육 �?�완제�?� 메�?살론(metaxalone)�?� 기준치보다 수천배 �?� 많�?� 함유�?� 있었다고 연구팀�?� �?혔다. 환경 관리청�?� 실시한 �? 다른 검사 결과 미시간주�? 데일리팜

King Pharmaceuticals Reports Year-End and Fourth-Quarter 2008 ...  -  ‎Feb 26, 2009‎
...our cost base due to a recent court decision which has increased the uncertainty regarding the continued exclusivity of SKELAXIN(R) (metaxalone). Trading Markets (press release)

King Pharma Purges 22 Percent of its Workforce  -  04 Feb 2009
The cuts come two weeks after a US District Court judge invalidated two of the three patents on King’s muscle relaxant Skelaxin (metaxalone). PharmExec.com,

King Pharmaceuticals' restructuring cutting another 520 jobs  -  Feb 3, 2009
Brian A. Markison, chairman, president and chief executive officer of King, said, "Following the recent court decision relating to our Skelaxin (metaxalone) Kingsport Times News,

US court invalidates King patents on Skelaxin  -  Jan 21, 2009
King also said that Sandoz has yet to receive US approval for an application to market a generic version of Skelaxin, also known as metaxalone. Reuters

킹, 특허 잃고 대대�? �?�력�?축  -  Feb 3, 2009
...킹 파마슈티컬스(King Pharmaceuticals)가 주력 제품�?� 근육 �?�완제 ‘스켈�?�신’(Skelaxin, metaxalone)�?� 특허를 잃고 대대�? �?�력�?축�?� 실시한다. 디지틀보사,

King Pharmaceuticals Reports Third-Quarter 2008 Financial Results  -  Nov 6, 2008
Net sales of SKELAXIN ® (metaxalone) totaled $110 million during the third quarter of 2008, compared to $106 million during the same period of the prior istockAnalyst.com (press release),

King Pharmaceuticals Reports Second-Quarter 2008 Financial Results  -  07 Aug 2008
Net sales of SKELAXIN(R) (metaxalone) totaled $107 million during the second quarter of 2008, compared to $108 million during the same period of the prior Trading Markets (press release),

King Pharmaceuticals Reports Second-Quarter 2008 Financial Results  -  07 Aug 2008
Net sales of SKELAXIN ® (metaxalone) totaled $107 million during the second quarter of 2008, compared to $108 million during the same period of the prior Business Wire (press release),

Use of Muscle Relaxants for Musculoskeletal Conditions Reviewed  -  Aug 5, 2008
The most commonly prescribed antispasmodic agents are carisoprodol, cyclobenzaprine, metaxalone, and methocarbamol. A meta-analysis of cyclobenzaprine Medscape (subscription)

People With Dementia Should Avoid Certain Drugs  -  Jun 27, 2008
Muscle relaxants such as Carisoprodol (Soma), Chlorzoxazone (Parafon Forte), Cyclobenzaprine (Flexeril), Metaxalone (Skelaxin), Methocarbamol (Robaxin) and RedOrbit,

King Pharmaceuticals Reports First-Quarter 2008 Financial Results  -  May 8, 2008
Net sales of SKELAXIN ® (metaxalone) totaled $116 million during the first quarter of 2008, compared to $112 million during the same period of the prior Business Wire (press release),

Management of Bleeding and Bruising Disorders Reviewed  -  23 Apr 2008
Medications rarely causing bleeding and bruising are cephalosporins, Ginkgo biloba, gold, interferon, metaxalone (Skelaxin; Carnrick Laboratories Inc), Medscape (subscription)

UPDATE: Novartis' Generic Lovenox Launch In 2008 Still Possible  -  Apr 21, 2008
..."Our growth rates in the US depend on generic Lovenox and metaxalone," Rummelt said. Metaxalone is the generic name of Skelaxin, a muscle relaxant sold by EasyBourse.com,

King Pharmaceuticals Reports Year-End and Fourth-Quarter 2007 ...  -  Feb 28, 2008
Net sales of SKELAXIN(R) (metaxalone) totaled $114 million during the fourth quarter and $440 million for the year ended December 31, 2007, compared to $113 Centre Daily Times,

King Pharma's Golden Deal  -  Jan 8, 2008
...based company filed with the Securities and Exchange Commission, stating that it signed a metaxalone 800 milligram product agreement on January 2. Forbes,

King Pharmaceutical shares up on news of patent lawsuit dismissal  -  Jan 8, 2008
2, King will grant Core a nonexclusive license to make and sell a 400 mg metaxalone product, in what amounts to a generic form of Skelaxin. CNNMoney.com

King Pharma Ends Suit Vs CorePharma  -  Jan 8, 2008
...based King said it signed a metaxalone 800 mg product agreement on Jan. 2 granting CorePharma certain rights for an authorized generic version of the Forbes,

Exiting My King Pharma Position with a Nice Gain  -  Jan 9, 2008
Under the agreement CorePharma will be allowed to make an authorized generic version of Metaxalone 800 mg, as well as CorePharma's generic 800 mg metaxalone Seeking Alpha,

King Pharmaceuticals Inc. gains over 16 percent after agreement ...  -  Jan 8, 2008
Securities and Exchange Commission that the company has signed an agreement with CorePharma to offer the latter with some rights for metaxalone 800 mg. TopNews,

Tuesday's Winners & Losers: King Pharmaceuticals  -  Jan 8, 2008
The companies signed a license agreement on January 2 that gave CorePharma certain rights to metaxalone 800 mg. King's shares were trading up $1.69, TheStreet.com

CorePharma to Sell Authorized Generic Skelaxin  -  Jan 15, 2008
Under the agreement relating to 800-mg Skelaxin (metaxalone) tablets, CorePharma’s license will go into effect Dec. 1, 2012, or six months after the US FDA news (subscription),

King Pharmaceuticals Reports Third-Quarter 2007 Financial Results  -  Nov 8, 2007
Net sales of SKELAXIN(R) (metaxalone) totaled $106 million during each of the third quarters of 2007 and 2006. THROMBIN-JMI(R) (thrombin, topical, bovine, PharmaLive.com (press release),

King Pharmaceuticals Accelerates Strategic Shift to Maximize Long ...  -  Oct 19, 2007
In recent years, King has developed a strong pain management franchise, which includes existing products like SKELAXIN(R) (metaxalone) and AVINZA(R) PharmaLive.com (press release),

Understanding cultural wards the practice litigation cocaine.  -  05 Jul 2007
LIVE-Wintersport.com,Earlier initiation be if and fourth metaxalone lacking. Vero cell deranged in and compares function. Molecular tests of addictive in cont values.

King Pharmaceuticals Joins Together Rx Access(TM) To Help ...  -  Jun 11, 2007
Genetic Engineering News (press release),Skelaxin(R) (metaxalone); Avinza(R)(morphine sulfate extended release); Sonata(R) (zaleplon); and Levoxyl(R) (levothyroxine sodium tablets, USP).

King Pharmaceuticals Reports First-Quarter 2007 Financial Results  -  May 10, 2007
PharmaLive.com (press release),Net sales of SKELAXIN(R) (metaxalone) totaled $112 million during the first quarter of 2007, an increase of 14% compared to $99 million during the same

Charlotte family arrested during drug raid  -  Apr 6, 2007
The News-Press,Methamphetamine, marijuana, drug paraphernalia (scale, rolling papers, meth pipes, straws, and three bongs), Metaxalone, Restoril and Lorcet pills were

Family arrested, pit bulls taken in narcotics search  -  Apr 6, 2007
Charlotte Sun-Herald,Narcotics and K-9 units found methamphetamine, marijuana and three kinds of prescription pills -- Metaxalone, Restoril and Lorcet, the CCSO said.

Mom, dad, son, daughter among those in drug arrests  -  Apr 6, 2007
Charlotte Sun-Herald,The six arrested were charged with possessing and distributing methamphetamine, marijuana, Metaxalone, Restoril and Lorcet pills and possession of

King Pharmaceuticals Reports FDA Approval Of New Skelaxin Label  -  Dec 7, 2006
SpiritIndia,...today that the US Food and Drug Administration (“FDA�?) has approved the Company’s revised prescribing information for its Skelaxin® (metaxalone) product ...

King Pharmaceuticals Reports FDA Approval of New Skelaxin ® Label  -  Dec 4, 2006
Business Wire (press release),...today that the US Food and Drug Administration (“FDA�?) has approved the Company’s revised prescribing information for its Skelaxin ® (metaxalone) product ...

King Pharmaceuticals Reports Third-Quarter 2006 Financial Results  09 Nov 2006
Net sales of Skelaxin(R) (metaxalone) totaled $106 million during the third quarter of 2006 compared to $116 million during the same period of the prior year. ... -PharmaLive.com (press release), King Pharmaceuticals Announces Strategic Acquisition of Avinza(R) ...  Sep 7, 2006
SKELAXIN(R) (metaxalone): A non-narcotic and non-addictive muscle relaxant that brings relief to muscle regions affected by pain and discomfort, especially ... -Business Wire

King Pharmaceuticals reports 8% second quarter total revenues ...  Aug 9, 2006
Net sales of Skelaxin(R) (metaxalone) totaled $97 million during the second quarter of 2006, an increase of 12% compared to $87 million during the same period ... -Kingsport Times News

King Pharma Q1 Adj. EPS Beats Street Expectations; Revenues Climb ...  May 9, 2006
Net sales of Skelaxin (metaxalone), a drug indicated as an adjunct to rest, physical therapy, totaled $99 million during the first quarter of 2006, an increase ... - Trading Markets

King Pharmaceuticals Reports First-Quarter 2006 Financial Results  May 9, 2006
Net sales of Skelaxin(R) (metaxalone) totaled $99 million during the first quarter of 2006, an increase of 37% compared to $72 million during the same period ... - PR Newswire

Medicare drug plans causing headaches  Mar 19, 2006
...frustration. Marek had been on the muscle relaxant metaxalone for years, Argoff said. But her new drug plan wouldn't pay for that drug. ... - Record-Searchlight (subscription)

King Pharmaceuticals Reports Year-End and Fourth-Quarter 2005 ... Feb 28, 2006
Inventory levels of Skelaxin(R) (metaxalone) and Altace(R) (ramipril) were each slightly higher than one month of estimated end-user demand as of the end of ... - Black Enterprise,

Pain Therapeutics and King Pharmaceuticals Receive Special ...  Feb 16, 2006
...people. King's growing line of branded products includes neuroscience drugs such as Skelaxin® (metaxalone) and Sonata® (zaleplon). ... - Yahoo! News

Murder defendant indicted on new charge  Jan 11, 2006
...other counts for possessing the controlled substances of Oxycodone and Acetaminophen, Alprazolam, Penicillin, Hydrochlorothiazide, and Metaxalone without a ... - Clarke Times Courier

Brand Names/Synonyms:
Metaxalone is also known by the following brand names and/or synonyms.Meta.Xalon; .Meta.Xalone; .Meta.Zalone; .Meta.Zolone; AHR 438; AHR-438; HSDB 3236; Metassalone [Dcit]; Metaxalon; Metaxalona [Inn-Spanish]; Metaxalona [Spanish]; Metaxalone; Metaxalone [Usan:Ban:Inn]; Metaxalonum [Inn-Latin]; Metaxalonum [Latin]; Metazalone; Metazolone; Methaxalonum; Methoxolone; Skelaxin; Zorane

Drug Category:
Metaxalone is categorized under the following by the FDA: Muscle Relaxants, skeletal muscle; Analgesics; Hypnotics and Sedatives;

Dosage Forms:
Tablet

Absorption:
Not Available

Interactions:
Interactions for Metaxalone:

SKELAXIN may enhance the effects of alcohol, barbiturates and other CNS depressants.

Chemical IUPAC Name:
5-[(3,5-dimethylphenoxy)methyl]oxazolidin-2-one

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