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LortabThis page contains recent news articles, when available, and an overview of Lortab but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.Overview: Lortab (when available) When 800 mg Valstar was administered intravesically to patients with carcinoma in situ, Valstar penetrated into the bladder wall. The mean total anthracycline concentration measured in bladder tissue exceeded the levels causing 90% cytoxicity to human bladder cells cultured in vitro. During the two-hour dose-retention period, the metabolism of Valstar to its major metabolites N-trifluoroacetyladriamycin and N-trifluoroacetyladriamycinol was neglible. After retention, the drug was almost completely excreted by voiding the instillate. Mean percent recovery of Valstar, N-trifluoroacetyladriamycin, and total anthracyclines in 14 urine samples from six patients was 98.6%, 0.4%, and 99.0% of the total administered drug, respectively. During the two-hour dose-retention period, only nanogram quantities of Valstar were absorbed into the plasma. Bladder cancer Mechanism Of Action: Valrubicin is an anthracycline that affects a variety of inter-related biological functions, most of which involve nucleic acid metabolism. It readily penetrates into cells, where it inhibits the incorporation of nucleosides into nucleic acids, causes extensive chromosomal damage, and arrests cell cycle in G2. Although valrubicin does not bind strongly to DNA, a principal mechanism of its action, mediated by valrubicin metabolites, is interference with the normal DNA breaking-resealing action of DNA topoisomerase II. News Articles on Valrubicin Task force continues fight against illegal drugs - 30 Aug 2009 Hydrocodone (branded as Lortab, Lorcet and a number of other trademarks) was the number one drug agents dealt with last year. Princeton Times Leader Many elude drug sweep - Aug 27, 2009 ...>Bonnie Ruth, 22, two counts of second-degree trafficking in a controlled substance (lortab) and trafficking in a legend drug. She's jailed on a $10000 full State-Journal.com 2 arrested in Durant on drug charges - Aug 28, 2009 Inside police found several blue pills that were later identified as Lortab. Police also found marijuana and a baggy with white residue inside Soester's KXII-TV Search warrants result in drug arrest in Dothan - Aug 28, 2009 A pair of search warrants served Thursday yielded one arrest and the seizure of 75 grams of cocaine and 11 Lortab pills. Dothan Eagle 14 targeted in Franklin drug sweep - Aug 26, 2009 ...detectives bought crack and powder cocaine, and various prescription pills, including OxyContin, Percocet, hydrocodone, Lortab and liquid morphine. Kentucky.com Jackson police investigating forged prescription passed at Mac's Drugs - Aug 26, 2009 The prescription was for Lortab, Chief Charles Burge explained. Burge said police have a suspect but no arrest has been made. South Alabamian Blackjack dealer at Tri-State accused of cheating - Aug 25, 2009 Officers recovered a Lortab pill and a snorting device from Maple's pocket, troopers said. Thuhuong and Maple were charged with violating racetrack rules. Daily Mail - Charleston Taylorsville robbers take man's shorts, drugs, cash - Aug 18, 2009 ..."They took some medication -- particularly Lortab and OxyContin," Martinez said. "They also took the pair of shorts he had on, which contained his wallet Salt Lake Tribune Huntington HS teacher arrested - Aug 25, 2009 12 Forcht smelled of alcohol and was slurring his speech. Bossier officers say they later found Lortab and Viagra tablets on Forcht without a prescription. KSLA-TV Woman jailed in drug case - Aug 24, 2009 Hydrocodone is a narcotic pain reliever also sold under the trade names Norco and Lortab. Following a month-long investigation, members of the department's Visalia Times-Delta Two arrested on drug charges - Aug 26, 2009 PANAMA CITY BEACH - Beach police arrested two people on drug charges Monday after they were found in possession of Lortab, The News Herald Authorities, citing drugs and prostitution, shut down Pascagoula bar - Aug 7, 2009 Marie Ladiner, a bartender, was charged Thursday with misdemeanor possession of Lortab. District Attorney Tony Lawrence said that Rooster's would remain The Mississippi Press - gulflive.com West Monroe residents arrested on suspicion of narcotics - Aug 18, 2009 Stephenson was booked on charges of possession of Xanax and possession of Lortab; Glasscock was booked on charges of distribution of Xanax and distribution Monroe News Star Oklahoma families battle chemical demons: Linda and Chase Morgan - Aug 22, 2009 ..."Lortab,â€? he said. "They took it. I didn't.â€? He suddenly lunged for the side of the bed. That morning in May 2006, it seemed as if he'd never stop vomiting. NewsOK.com Oklahoma City suspect charged in child porn case - Aug 17, 2009 ...the police detective reported. Rogers has been on probation since September for misdemeanor possession of marijuana and the drug Lortab. NewsOK.com 'How did you get in my house' man shouts at police officers - Aug 10, 2009 She said he'd been taking Xanax earlier. Officers found an unlabeled prescription bottle with 55 Xanax tablets and one Lortab. The Northwest Florida Daily News Mom in deadly crash may have hid her addiction - Aug 10, 2009 His dentist, among other treatments, prescribed antibiotics to treat the infection and Lortab to manage the constant, throbbing ache. Deseret News Part 17 of 20 - Wrong-way Interstate Collisions, “This is a broad ... - Aug 13, 2009 The drug was Lortab. Vigil admitted to taking the powerful narcotic Lortab before driving. He then failed a series of sobriety tests. InjuryBoard.com Pharmacy tech charged with theft of prescriptions - Aug 7, 2009 Among the drugs Montgomery was accused of taking are morphine, Lortab and Percocet, all prescription narcotics. Reports indicate she had been working at the Times Daily Birmingham doctor pleads guilty to drug possession - Aug 13, 2009 In July 2008, Baker ordered 5000 tablets of Hydrocodone, also known as Lortab. The order roused the suspicion of the DEA. Baker's order history, according al.com Davis County gives badges to 3 new K9 officers - Aug 11, 2009 But the largest find was 16 grams of crack cocaine, 60 Lortab pills and other drugs. Part of the money used to buy the dogs came from the Val A. and Edith ABC 4 McMinn County Woman Charged with TennCare Fraud - Aug 19, 2009 Katherine A. Woody, also known as Katherine A. Clark, is accused of altering the number of pills prescribed on a legitimate prescription for Lortab, WRCB-TV Traffic stop by state trooper nets drug arrest - Aug 19, 2009 Copeland was arrested during a traffic stop on Saturday near the intersection of Judge Logue Road and Cumbie Road. The state trooper seized four Lortab Dothan Eagle Police blotter: Huntington man reports ATV, tools stolen from garage - Aug 28, 2009 The drugs included Lortab, Detrol and Zoloft. LARCENY: A complainant from the Sixth Avenue Church of Christ reported that someone stole the copper piping Huntington Herald Dispatch Greenville County summer gang sweep yields guns, drugs - Aug 27, 2009 The drug haul included more than a pound of marijuana and more than two pounds of cocaine, along with crack, heroin, meth, Valium and Lortab, Loftis said. Greenville News Getting Educated on Painkillers - Aug 6, 2009 Frequent kidney stones and long term joint pain led to his doctor prescribing two painkillers, Vicodin and Lortab. While they were effective at managing his HULIQ Some patients concerned over new recommendations for acetaminophen use - Aug 24, 2009 ..."Acetaminophen works as a great adjunct with narcotic painkillers, like the main ingredient in Lortab or Percocet. It has a synergistic effect," he said, StandardNet Watching the neighborhood / Use Tip-A-Cop to report suspicious ... - Aug 24, 2009 Agents arrested the 24-year-old man and confiscated marijuana, and Oxycontin and Lortab pills. The man was charged with one misdemeanor and two felony StandardNet Twenty-four arrests made in Campbell Co. drug investigation - Aug 21, 2009 The suspects were charged with offenses involving cocaine, marijuana, oxycotin, percocet, and lortab. The suspects reside throughout Central Virginia. Brookneal Union Star Driver 'sorry,' gets 7 years in fatal crash - Aug 14, 2009 She had tincture of opium and lortab, painkillers prescribed to McDole, in her system afterward. "This is a very, very sad case," Judge Linley Pearson said Journal and Courier Sheriff's office files drug charges - Aug 12, 2009 LT Guthrie said the charges covered a wide variety of narcotics violations and involved cocaine, marijuana, oxycotin, percocet and lortab. Altavista Police blotter: More than $1600 in items stolen from 25th Street ... - Aug 19, 2009 Missing items include a Nintendo Wii, air compressor, a Taurus 9-millimeter handgun, a pistol, 55 Lortab tablets and a digital camera. Huntington Herald Dispatch Crime Report — West Des Moines, Clive, Waukee - Aug 7, 2009 3700 block of EP True Parkway, July 29 - Police arrested a 19-year-old West Des Moines man for possession of Lortab-a schedule III narcotic-drug DesMoinesRegister.com Elderly Fall Branch couple indicted for selling drugs at home - Aug 7, 2009 Shawn Judy said the couple was accused of mostly selling Lortab. Judy said investigators believe the couple would fill multiple prescriptions for their Kingsport Times News Bristol Blotter - Aug 14, 2009 With it, he lost $150 in clothes, $25 cash, nine packs of Marlboros, a 50-count bottle of Colnsapam and a nine-count prescription for Lortab. TriCities.com Three arrested in Oliver Springs traffic operation - Aug 13, 2009 During the search of Roberts' motorcycle, Laxton found two pounds of marijuana, 59 Oxycontin pills (80 mg), 15 Xanax pills, 33 Lortab pills (10 mg), Oak Ridger POLICE REPORT - Aug 17, 2009 According to the Cherokee County Sheriff's Office, someone gained entry to the home between 9 pm and 11 pm and took the drugs Xanax and Lortab. Gaffney Ledger (subscription) Stopped for racing: 'I know it was stupid' - Aug 12, 2009 During the search, officers found a cigarette box that contained three Lortab pills, a prescription medical container that held one teaspoon of codeine The News Herald Nurse's care under review; join the conversation - Aug 16, 2009 Those prescriptions were for a variety of medications, including the painkillers Norco, Lortab, hydrocodone and oxycodone; the anti-anxiety drugs Xanax, The Daily Advertiser Fourth Officer Resigns After Clinic Raid - Aug 11, 2009 The documents detail how Tennessee Bureau of Investigation agents, using an undercover informant, were able to obtain hydrocodone and lortab without a WSMV Charge reduced in trafficking case - Aug 6, 2009 Gray's search of the car uncovered a drawstring bag in the rear of the car that contained 7.8 ounces of marijuana, 22 OxyContin pills, 10 Lortab pills and a Richmond Register Woman arrested in connection with drug buys - Aug 12, 2009 Sierra L. Machnicki was arrested after two grams of meth and 27 Lortab pills were purchased in buys Friday and Tuesday, said Lt. Jim Norton, commander of Salina Journal Steven Samra - Aug 19, 2009 No one will fill Codeine or Hydrocodone (Vicodin, Lortab, etc), but if you've received a script for something stronger, it's in your best interest not to Change.org Local briefs: Crash at checkpoint leads to DUI arrest - Aug 22, 2009 Hydrocodone is commonly known by trademark names such as Vicodin, Norco and Lortab. During a search of her home Friday, police found receipts, Fresno Bee Allegedly drunk dad designates 9-year-old as driver - Aug 3, 2009 According to the affidavit, Dewitt admitted to taking Lortab, a prescription pain medication. Cahoon also noted that several containers of alcoholic Journal and Courier Brand Names/Synonyms: Lortab is also known by the following brand names and/or synonymsAD 32; Antibiotic Ad 32; Valrubicin; Valrubicin [Usan]; Valstar; Valstar Preservative Free Drug Category: Lortab is categorized under the following by the FDA: Antineoplastic Agents; ATC:L01DB09 Dosage Forms: LIQUID Absorption: Not Available Interactions: -->Interactions for Valrubicin: Because systemic exposure to ValstarÔ is negligible following intravesical administration, the potential for drug interactions is low. No drug interaction studies were conducted. Chemical IUPAC Name: [2-oxo-2-[2,5,12-trihydroxy-4-[5-hydroxy-6-methyl-4-(2,2,2-trifluoroacetyl)amino-tetrahydropyran-2-yl]oxy-7-methoxy-6,11-dioxo-1,2,3,4-tetrahydrotetracen-2-yl]-ethyl]pentanoate : |
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