Librium

This page contains recent news articles, when available, and an overview of Librium but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Librium
(when available)

Pharmacology and use:
Chlordiazepoxide has antianxiety, sedative, appetite-stimulating and weak analgesic actions. The precise mechanism of action is not known. The drug blocks EEG arousal from stimulation of the brain stem reticular formation. The drug has been studied extensively in many species of animals and these studies are suggestive of action on the limbic system of the brain, which recent evidence indicates is involved in emotional responses. Hostile monkeys were made tame by oral drug doses which did not cause sedation. Chlordiazepoxide revealed a "taming" action with the elimination of fear and aggression. The taming effect of chlordiazepoxide was further demonstrated in rats made vicious by lesions in the septal area of the brain. The drug dosage which effectively blocked the vicious reaction was well below the dose which caused sedation in these animals. For the management of anxiety disorders or for the short-term relief of symptoms of anxiety, withdrawal symptoms of acute alcoholism, and preoperative apprehension and anxiety.

Mechanism Of Action:
Chlordiazepoxide binds to stereospecific benzodiazepine (BZD) binding sites on GABA (A) receptor complexes at several sites within the central nervous system, including the limbic system and reticular formation. BZDs enhance GABA-mediated chloride influx through GABA receptor channels, causing membrane hyperpolarization. The net neuro-inhibitory effects result in the observed sedative, hypnotic, anxiolytic, and muscle relaxant properties.

News Articles on Chlordiazepoxide

Did Alleged Killer of Sandra Cantu Abduct Another Little Girl?  -  20 Apr 2009
...girl's family then took her to the hospital, where doctors found benzodiazepines (a class of drugs that includes Valium and Librium) in her bloodstream. People Magazine

THE MYTH OF MARILYN  -  ‎Apr 15, 2009‎
When working on her last movie, she would sometimes have a dinner that consisted of three ounces of steak, one Librium, one chloral hydrate, one Nembutal Cleveland Scene Weekly

Sickening trend of legal drug addiction  -  ‎Apr 13, 2009‎
...psycho pharmacologist who, despite my objections, prescribed one of the new benzodiazepines (a class of drug that includes Valium, Librium, Klonopine). Talk Radio News Service

Eco Fest Vision Starts to Take Shape  -  ‎Apr 1, 2009‎
Debbie Plopper, special projects manager for Conway Sanitation, said "Eco-Librium" is a key word for the event because the planners want to present all KATV

Overhaul of services after teacher's death  -  ‎Mar 30, 2009‎
The inquest heard that Miss Owen had suffered mental health problems with anxiety and depression and was treated with the drug librium for two years. Grimsby Telegraph

What is Generalized Anxiety Disorder?  -  ‎Apr 18, 2009‎
Antidepressants, such as Paxil and Effexor XR, benzodiazepines, such as Ativan, Xanax, Librium, Klonopin, and Valium, beta-blockers, and busparine may all Examiner.com

GARDEN ROUTE NEWSPAPER  -  ‎Apr 9, 2009‎
Please note that the next qualifier will be held at Equine-Librium on May 16. Shoprite Checkers has pledged R10 000 towards the NSRI Awareness Campaign, CXpress

Depression Linked to Drugs Commonly Given to ICU Patients  -  ‎Apr 13, 2009‎
Benzodiazepine drugs, which include Xanax (alprazolam), Librium (chlordiazepoxide), Valium (diazepam), and Ativan (lorazepam), are frequently prescribed to Natural News.com

Check out the weekend sport offerings  -  ‎Apr 9, 2009‎
...and Jerry Yester of the Lovin' Spoonful. Columbian Theatre, Wamego. Live music Evolution of Pain, Librium, Blood In The Wire and Balldozer, 8 pm PJ's Pub. Manhattan Mercury

Court reports  -  ‎Apr 2, 2009‎
Jordan said she had taken two Librium pills, and consumed vodka and beer. At Chambersburg Hospital pills in her purse were identified as Xanax. Echo Pilot

Too Good to Be True  -  ‎Apr 1, 2009‎
The FDA found that the Brazilian diet pills also contained active ingredients also found in Librium, used to alleviate anxiety, and Prozac, Newsweek

Robyn Hitchcock's new album 'is a masterpiece'  -  ‎Apr 4, 2009‎
...while TLC seems like a love song which lopes along before the cat is out of the bag when he sings the chorus line "Triptisol, Librium, Carbatrol". Daily Gleaner

Optimism brews, but the bad news bubbles away  -  ‎Apr 1, 2009‎
Is Starbucks slipping Librium into its Pike Place Blend? How does anyone look at the latest numbers and think things are looking up? The National

Why I blame myself for the murder of Sixties playwright Joe Orton ...  -  ‎Apr 3, 2009‎
...'He's on valium, librium, speed, Nembutal and every other pill he can lay hands on. It's making him unbearable. 'I know I've got to leave him. Daily Mail

La mariguana y la hipocresía de los legisladores  -  ‎Apr 16, 2009‎
La legalización de las drogas, es decir, su venta controlada en farmacias, como es el caso de las benzodiacepinas (Xanax, Tafil, Lexotan, Librium, Risolid, La Jornada (México)

El consumo de tabaco y drogas se dispara entre los jóvenes con ...  -  ‎Apr 7, 2009‎
...cuatro grupos: marihuana (cannabis o hachís), estimulantes (cocaína, crack, anfetaminas o speed), opiáceos, heroína y tranquilizantes (Valium, Librium. Faro de Vigo

You See Obammas Tech Guru Gets Locked up  -  ‎Mar 13, 2009‎
With this kind of manic episode, I would think Librium might be a more effective management tool. GO AWAY!! and bother MiddleClassBill he seems to like it. TPMCafé

Your Life: Why Is Trying To Keep Fit Such A Pain?  -  ‎Mar 14, 2009‎
If you have been drinking every day, you will need a detox with a benzodiazepine, such as Librium, and vitamins. To keep you sober, there is a medication Glasgow Sunday Mail

Withdrawal symptoms can vary  -  ‎Mar 3, 2009‎
Other drugs in this class are clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan) and chlordiazepoxide (Librium). I'm not sure I would use the word Times Daily

March 2009 Mayo Clinic Health Letter Highlights Knee Repair ...  -  ‎Mar 10, 2009‎
Drugs in this category include alprazolam (Xanax), chlordiazepoxide (Librium), clonazepam (Klonopin), diazepam (Valium) and lorazepam (Ativan). PR Newswire (press release)

Prescribing practices called into question  -  ‎Feb 23, 2009‎
By the mid-1980s, there were 17 benzodiazepines on the market, including Librium and Valium, but it has since been found that regular use leads to loss of Irish Times

Research points to increased drug use among Travellers  -  ‎Mar 5, 2009‎
...alcohol with benzodiazepines (psychoactive prescribed drugs such as Valium, Mogadon and Librium); benzodiazepines with Solpadeine; Solpadeine with Waterford Today

NJ-based Roche shedding more than 1500 jobs in Genentech deal  -  ‎Mar 12, 2009‎
...a business it later moved to Warren County -- and then returned to making medicines, including widely-used tranquilizers such as Librium and Valium. The Star-Ledger - NJ.com

Four at Four: Banks Get Blasted — Again  -  ‎Feb 19, 2009‎
Please cut your Martini intake to 12 a day and lay off those square polka dot darcoset/librium combo pills. Whoa Nellie. Introduction. Wall Street Journal Blogs

1%Club kondigt eigenzinnige decemberacties aan  -  ‎Mar 15, 2009‎
NogHarder.nl (animatie), Mechanicus.nl (montage), ScreamingScreen.com (sound), Palookaville, ON, Librium, Mia Media, Reality Outdoor en Minima Fair. HappyNews

Opvallende uitslag (on) gewenste intimiteiten enquete  -  ‎Mar 4, 2009‎
HDC Media, Holland Combinatie, Basismedia, Telegraaf Tijdschriften Groep, WebRegio Media, Pilarczyk Mediagroep, Telegraaf Productiehuis en Librium TV. Ezpress (persbericht)

Dover man claims 'pathological intoxication' in deaths of Kinnelon ...  -  Jan 28, 2009
Authorities have said that Baum was drunk on vodka, under the influence of the anti-anxiety drug Librium, and driving on the road shoulder when he allegedly Dailyrecord.com,

To Cut Costs, GM May Stop Making Cars  -  Jan 30, 2009
Why don't you just take away my Librium too and I can just curl up into a ball and cry until I dehydrate to death?" Hurwitz also noted that you don't have Crystal Air Productions (satire),

Toronto paramedic tells all: The Emergency Monologues  -  Feb 2, 2009
Celexa, Prozac, Zoloft, Effexor, Wellbutrin, Thorazine, Haldol, Zyprexa, Seroquel, Risperdal, Lithium, Tegretol, Ritalin, Valium, Librium, Antabuse… National Post,

Our most anxious times  -  Jan 24, 2009
Tone's thoughtful, engaging book focuses on the development and phenomenal success of tranquilizers like Miltown, Valium and Librium during the 1950s and The Gazette (Montreal),

Police blotter - January 14, 2009  -  Jan 13, 2009
Police allegedly found 83.8 grams of marijuana, 23 Librium pills and firearms Coley is not allowed to possess because of prior convictions, accoording to Fort Mills Times,

What About Pain Pills and Similar Medications?  -  Jan 17, 2009
Valium, Xanax, Ativan, Librium, Paxipam, Restoril, Serax, Tranxene, and Centrax are older versions of medications often prescribed to resolve all kinds of NewsReleaseWire.com (press release)

Waking Up from the American Dream, 1950s Style  -  Jan 9, 2009
...life of the stay-at-home mom are painted neatly into this film until the its hard-core undertow drowns away the bunny-and-rainbow-Librium fifties fog. Huffington Post,

Narrowcasting Spits in trams GVB (Amsterdam)  -  Jan 23, 2009
De marketing en sales van het kanaal wordt door Librium.TV gedaan. In samenwerking met Librium.TV produceert Sp!ts voor dit kanaal het actuele nieuws en DigitaalMedia,

John van Rooy: de beste allround student van Nederland  -  Feb 3, 2009
Holland Combinatie, Basismedia, Telegraaf Tijdschriften Groep, WebRegio Media, Pilarczyk Mediagroep, Telegraaf Productiehuis, Librium TV en 402EVENTS. Nieuwsbank (persbericht) (abonnement),

Daten in het donker groot succes  -  Jan 20, 2009
HDC Media, Holland Combinatie, Basismedia, Telegraaf Tijdschriften Groep, Pilarczyk Mediagroep, Telegraaf Productiehuis, WebRegio Media en Librium TV. Nieuwsbank (persbericht) (abonnement),

Distributie én narrowcasting Sp!ts bij McDonald's  -  Jan 19, 2009
HDC Media, Holland Combinatie, BasisMedia, Telegraaf Tijdschriften Groep, WebRegio Media, Pilarczyk Mediagroep, Telegraaf Productiehuis en Librium TV. Nieuwsbank (persbericht) (abonnement),

Psicofarmaci responsabili della violenta morte di Maria Borghini?  -  Jan 10, 2009
Alcuni nomi in commercio sono: Frisium, Transene, En, Librium, Psicofar, Reliberan, Seren Vita, Madar, Madar Notte, Aliseum, Ansiolin, Eridan, Noan, Nopsych,

When the Market Matters -- and When It Doesn't  -  Dec 1, 2008
The produce is lousy, the meat is lousy, and the staff moves like they put Librium in the employee coffeemaker. I tell her I'll brave the traffic. Motley Fool

The Wholesale Sedation of America’s Youth  -  Dec 9, 2008
First, a new, safer class of sedative hypnotics, the benzodiazepines, including Librium and Valium, were an instant sensation, especially among housewives Skeptical Inquirer

Alcoholics clinics boost for Skye care  -  Dec 11, 2008
The clinics will supply patients with a five-day course of Chlordiazepoxide, which is better known as Librium, and is used to counter the physical symptoms Aberdeen Press and Journal,

Opatija - Eksklusivt turiststed siden 1800-tallet  -  Dec 19, 2008
Dette er mannen som mens han jobbet for legemiddelgiganten Roche klarte å fremstille beroligende midler som Librium og Valium. Han er patentinnehaver for Feriepenger,

Nr 1 werkgever 2008 onder hoogopgeleide studenten en starters Het Rijk  -  Dec 19, 2008
Holland Combinatie, Basismedia, Telegraaf Tijdschriften Groep, WebRegio Media, Pilarczyk Mediagroep, Telegraaf Productiehuis, Librium TV en 402EVENTS. Nieuwsbank (persbericht) (abonnement),

1%CLUB kondigt eigenzinnige decemberacties aan.  -  Dec 12, 2008
NogHarder.nl (animatie), Mechanicus.nl (montage), ScreamingScreen.com (sound), Palookaville, ON, Librium, Mia Media, Reality Outdoor en Minima Fair. Oneworld,

CREATIEVE BUREAUS EN FREELANCERS WERKEN BELANGELOOS SAMEN AAN ...  -  Dec 18, 2008
Conspiracy Concepts is verantwoordelijk voor de brede media inzet in samenwerking met Librium, ON en Mia Media. Voor deze schermen werd een 1%CLUB animatie Nieuwsbank (persbericht) (abonnement),

Studenten en starters verschuiven naar 'doelgerichte ondernemers'  -  Dec 11, 2008
HDC Media, Holland Combinatie, Basismedia, Telegraaf Tijdschriften Groep, WebRegio Media, Pilarczyk Mediagroep, Telegraaf Productiehuis en Librium TV. Nieuwsbank (persbericht) (abonnement),

De Telegraaf gaat luxe  -  Dec 11, 2008
HDC Media, Holland Combinatie, Basismedia, Telegraaf Tijdschriften Groep, WebRegio Media, Pilarczyk Mediagroep, Telegraaf Productiehuis en Librium TV. Ezpress (persbericht),

De Telegraaf brengt VROUW op mobiel  -  Dec 9, 2008
HDC Media, Holland Combinatie, Basismedia, Telegraaf Tijdschriften Groep, WebRegio Media, Pilarczyk Mediagroep, Telegraaf Productiehuis en Librium TV. Ezpress (persbericht),

Sinterklaas erg populair onder jongeren  -  Dec 4, 2008
HDC Media, Holland Combinatie, Basismedia, Telegraaf Tijdschriften Groep, WebRegio Media, Pilarczyk Mediagroep, Telegraaf Productiehuis en Librium TV. Nieuwsbank (persbericht) (abonnement),

Succesfactoren online dating wetenschappelijk aangetoond  -  Dec 3, 2008
HDC Media, Holland Combinatie, Basismedia, Telegraaf Tijdschriften Groep, Pilarczyk Mediagroep, Telegraaf Productiehuis, WebRegio Media en Librium TV. Nieuwsbank (persbericht) (abonnement),

MARCO BORSATO GASTHOOFDREDACTEUR VAN VROUW MAGAZINE  -  Dec 1, 2008
HDC Media, Holland Combinatie, Basismedia, Telegraaf Tijdschriften Groep, WebRegio Media, Pilarczyk Mediagroep, Telegraaf Productiehuis en Librium TV. Nieuwsbank (persbericht) (abonnement),

Manhattan Does Drizzle: Rainy Days And Sarah Palin Make Me Cranky  -  Nov 14, 2008
...stuck as I was in traffic while Bush had the nerve to be here talking about the economy (as if he really knew the difference between LIBOR and Librium). Huffington Post,

The Strategy Institute Announces The 4th Annual Building Your ...  -  Nov 3, 2008
Emulate Their Success! with key panelists including: Mike Bosman, CEO, One Digital Media (South Africa); Tijmen Bos, Managing Partner, Librium. Retail Solutions Online (press release),

Mistakes in Medication  -  Nov 11, 2008
Listed as rarely appropriate includes Chlorodiazapoxide (Librium), Diazepam (Valium), Propoxyphene (Darvon), Carisoprodol (Soma) and more. Aiken Standard (subscription),

Chamber's annual awards recipients for 2008  -  Nov 2, 2008
Baxter is a former board member for the Pocono Mountains Chamber of Commerce, American Cancer Society, Equi-Librium, among others. Pocono Record,

Avandia, Rezulin and Actos: Same Chemical Family; Similar Benefits ...  -  Oct 31, 2008
To illustrate, let's review a group of psychoactive drugs belonging to the benzodiazepine family; Librium, Valium, and Dalmane. Each has a similar family InjuryBoard.com,

Disabled New Bedford boat towed to safety; Bourne Bridge pavement ...  -  Nov 8, 2008
According to Polive the Class C Substance examples include prescription tranquilizers and narcotics diazepam (Valium), Librium, Hydrocodone (Vicodin, Cape Cod Today,

Telegraaf verkoopt narrowcaster Media Librium  -  Nov 5, 2008
De Telegraaf nam eind 2005 een minderheidsbelang van 40 procent in Media Librium en breidde dat in juli 2007 uit tot 84 procent. Uit de halfjaarcijfers die Emerce,

Telegraaf stopt met bladen  -  Nov 5, 2008
Daarnaast wil het mediabedrijf af van de belangen in Media Librium, leverancier van digitale media, en magazines in Zweden en Oekraïne. NRC Handelsblad,

Die Nacht der GIER  -  Nov 18, 2008
Franz Norkus, Initiator und ehemaliger Besitzer solch großartiger Clubs wie des Model Traumwelt, Cocain, Librium und eben des Mudia Art, hat wohl wie kein virtualnights.de,

De publicistas y más  -  Oct 28, 2008
Y en aspectos sociales, las mujeres y su independencia, los medicamentos de moda para la ansiedad y el estrés como el 'Librium', anticonceptivos, esmas,

Telegraaf Media Group продает вÑ?е проекты в Украине  -  Nov 10, 2008
ПоÑ?тому группа выÑ?тавлÑ?ет на продажу Ñ?емь журналов и 84% акций оператора наружной рекламы Media Librium BV в Ð?идерландах, вÑ?е печатные и интернет-активы в NEWSru.ua,

Zalm: "We kunnen hier nog wel wat goede economen gebruiken"  -  Oct 29, 2008
HDC Media, Holland Combinatie, BasisMedia, Telegraaf Tijdschriften Groep, Pilarczyk Media Groep, Telegraaf Productiehuis en Librium TV. Nieuwsbank (persbericht) (abonnement),

TMG snijdt in titels  -  Nov 4, 2008
Het 84%-belang in Media Librium BV, marktleider in digitale out of home media. het portfolio van magazines en internetsites in het topsegment van de woon-, Admanager.nl,

Brand Names/Synonyms:
Librium is also known by the following brand names and/or synonymsA-Poxide; Abboxide; Apo-Chlordiazepoxide; Balance; CD 2; CDO; CDP; Chloradiazepoxide; Chlordiazachel; Chlordiazepoxid; Chlordiazepoxide; Chlordiazepoxide Base; Chlordiazepoxide Hcl; Chlordiazepoxidum; Chloridazepoxide; Chloridiazepide; Chloridiazepoxide; Chlorodiazepoxide; Chlozepid; Clopoxide; Clordiazepossido; Contol; Control; Decacil; Eden; Elenium; Helogaphen; Ifibrium; Kalmocaps; Librax; Librelease; Librinin; Libritabs; Librium; Limbitrol; Limbitrol Ds; Lygen; Menrium; Mesural; Methaminodiazepoxide; Mildmen; Multum; Napoton; Napton; Novo-Poxide; Psicosan; Radepur; Risolid; Silibrin; Tropium; Viopsicol

Drug Category:
Librium is categorized under the following by the FDA: Anti-anxiety Agents; Hypnotics and Sedatives; Adjuvants, Anesthesia; Benzodiazepines; GABA Modulators; ATC:N05BA02

Dosage Forms:
CAPSULE (5 mg, 10 mg or 25 mg)

Absorption:
Not Available

Interactions:
Interactions for Chlordiazepoxide: Although clinical studies have not established a cause and effect relationship, physicians should be aware that variable effects an blood coagulation have been reported very rarely in patients receiving oral anticoagulants and chlordiazepoxide. The concomitant use of alcohol or other central nervous system depressants may have an additive effect.



Chemical IUPAC Name:
10-chloro-3-hydroxy-N-methyl-2-phenyl-3,6-diazabicyclo[5.4.0]undeca-1,6,8,10-tetraen-5-imine

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