Librium

This page contains recent news articles, when available, and an overview of Librium but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Librium
(when available)

Pharmacology and use:
Chlordiazepoxide has antianxiety, sedative, appetite-stimulating and weak analgesic actions. The precise mechanism of action is not known. The drug blocks EEG arousal from stimulation of the brain stem reticular formation. The drug has been studied extensively in many species of animals and these studies are suggestive of action on the limbic system of the brain, which recent evidence indicates is involved in emotional responses. Hostile monkeys were made tame by oral drug doses which did not cause sedation. Chlordiazepoxide revealed a "taming" action with the elimination of fear and aggression. The taming effect of chlordiazepoxide was further demonstrated in rats made vicious by lesions in the septal area of the brain. The drug dosage which effectively blocked the vicious reaction was well below the dose which caused sedation in these animals. For the management of anxiety disorders or for the short-term relief of symptoms of anxiety, withdrawal symptoms of acute alcoholism, and preoperative apprehension and anxiety.

Mechanism Of Action:
Chlordiazepoxide binds to stereospecific benzodiazepine (BZD) binding sites on GABA (A) receptor complexes at several sites within the central nervous system, including the limbic system and reticular formation. BZDs enhance GABA-mediated chloride influx through GABA receptor channels, causing membrane hyperpolarization. The net neuro-inhibitory effects result in the observed sedative, hypnotic, anxiolytic, and muscle relaxant properties.

News Articles on Chlordiazepoxide

Benzodiazepines no joke  -  ‎Aug 28, 2009‎
Common drugs of abuse in this category are Valium, Klonopin, Librium, Ativan, and Xanax. Many opiate addicts will use benzodiazepines because they enhance Examiner.com

Benzodiazepine Effect: Inside Michael Jackson's Death  -  ‎Aug 28, 2009‎
The family of antianxiety drugs known as Benzodiazepines includes Alprazolam (Xanax), Chlordiazepoxide (Librium), Diazepam (Valium) and Lorazepam (Ativan). American Superstar Magazine

Father-of-five's killer is sentenced to life in jail  -  ‎Aug 7, 2009‎
Allen had also taken up to 30 librium tablets and smoked heroin. Some time during the night, Allen launched his ferocious attack, kicking and punching Mr Hamilton Advertiser news

Hope for the Hopelessly Drunk  -  ‎Aug 12, 2009‎
So I'd get panicky and go to the emergency room to get Librium, which they use along with some other stuff to prevent the seizures. San Diego Reader

Rescuers fear for koalas  -  ‎Aug 26, 2009‎
The project, called eco-librium, proposes to use 47ha and will have an 8.5eha eco corridor and 1.9ha of open recreation space. Moreton Bay Koala Rescue is a Where I Live - News Community Media

Mercury Rising Featuring Alex Jones  -  ‎Aug 10, 2009‎
Alex old mate-they invented psychiatry, librium and valium for nutbags like you. Try an overdose of all 3 What a great monolog, in joker face, Prison Planet.com

Bescheiden winst voor Telegraaf  -  ‎Aug 14, 2009‎
In juli werd Librium TV, een medium voor narrowcasting verkocht. Narrowcasting is het op televisies op specifieke plaatsen, zoals in trams, weergeven van De Telegraaf

Librium TV in handen van nieuwe eigenaar  -  ‎Aug 14, 2009‎
Librium TV-directeur Tijmen Bos bevestigt de overname aan Emerce. Het bedrijf staat sinds november 2008 in de etalage. De doorontwikkeling bij TMG lag stil Emerce

Slikare laÄ‘are opÄ?inila tisa  -  ‎Aug 9, 2009‎
Slikarska posada umetniÄ?ke flote, koju Ä?ine brodovi "Anamaria", "Rusalka" i "Librium", otplovila je ovog vikenda iz Novog BeÄ?eja put Kanjiže, Кurir

ПолициÑ? провела обыÑ?к в аптеке, ища улики против врача Майкла ДжекÑ?она  -  ‎Aug 11, 2009‎
Ñ?вÑ?зи Ñ? получением ДжекÑ?оном лекарÑ?тв, которые продаютÑ?Ñ? по рецептам. Речь идет о таких препаратах как кÑ?анакÑ? (Xanax), либриум (Librium) и валиум (Valium). K2Kapital

Buy valium without prescription, cheap valium without rx  -  13 Jul 2009
Librium had been developed to compete with a rival company's popular tranquilizer, Miltown. All of these new drugs were targeted at middle-class Americans, Cleveland Indy Media

Equi-Librium receives $2000 from Ladies Auxiliary 1106  -  ‎Jul 1, 2009‎
The Ladies Auxiliary of the Fraternal Order of Eagles 1106 held a Mother's Day breakfast to raise funds for Equi-Librium. They presented a check for $2000 Pocono Record

• Lehigh Valley Brewfest moving to Hugh Moore Park in Easton  -  ‎Jul 3, 2009‎
Beste chairs the board of directors for Equi-librium, which offers therapeutic horseback riding programs for those with special needs, including autism, The Express Times - LehighValleyLive.com

What's next for the guilty in the Cuyahoga County corruption case?  -  ‎Jul 2, 2009‎
Gallagher also said that he is being treated by a psychologist for stress and anxiety and taking prescription drugs Librium, Zoloft and Xanax . WKYC-TV

The Age of Anxiety: A History of America's Turbulent Affair With ...  -  ‎Jul 1, 2009‎
The story of meprobamate is followed by that of chlordiazepoxide (Librium) and other benzodiazepines discovered by another refugee, Leo Sternbach. Am J Psychiatry (subscription)

What Do Allen Stanford And Pete Townshend Have In Common? A Kick ...  -  ‎Jun 25, 2009‎
...[Ativan is chemically a close relative to Valium and Librium.] Now these Ativans were really the business. They made me feel incredibly good. Houston Press

State Board Revokes License of Wildwood Physician  -  ‎Jul 9, 2009‎
From October 28, 1989, to February 1, 1991, respondent prescribed for JB a variety of medications, including Zantac, Librium, Halcion, Xanax, Lithobid, Cape May County Herald

Narrowcasting AT5 op Librium.TV  -  ‎Jul 7, 2009‎
Naast op TV, internet en mobiel, is AT5 vanaf heden ook te volgen via het narrowcastingnetwerk van Librium.TV in de regio Groot Amsterdam. Zigt

è´§å¸?似蜜,最å?Žè¿˜æ˜¯æ°´  -  ‎Jun 22, 2009‎
...所以,最早å?‘明此说的哈耶克,更强调通货膨胀具有“æµ?体å?‡è¡¡â€?(afluidequi librium)的性质。[注1]相对价格的改å?˜ï¼Œå¯¹ä¸€äº›äººæ?¥è¯´å°±æ˜¯æ–°æŠ•资机会的出现。 易阔每日财经

Abaixo o centralismo Lísbio  -  ‎Jul 1, 2009‎
Hipóteses: Amero, Librium, Xanax, Aurius, ECU, CNY. Sugestão de Visita: O Manguito Rochoso da Ponta de Sagres. Um must. "Até se babem. TSF Online

El caso Jackson-Murray: Las sobredosis van en ascenso  -  ‎Jun 27, 2009‎
También está el analgésico Demerol, el antihistamínico Tavist, el Valium o Librium para la ansiedad, y el Cogentin a base de benztropina tanto para el Urgente 24

Did Alleged Killer of Sandra Cantu Abduct Another Little Girl?  -  20 Apr 2009
...girl's family then took her to the hospital, where doctors found benzodiazepines (a class of drugs that includes Valium and Librium) in her bloodstream. People Magazine

THE MYTH OF MARILYN  -  ‎Apr 15, 2009‎
When working on her last movie, she would sometimes have a dinner that consisted of three ounces of steak, one Librium, one chloral hydrate, one Nembutal Cleveland Scene Weekly

Sickening trend of legal drug addiction  -  ‎Apr 13, 2009‎
...psycho pharmacologist who, despite my objections, prescribed one of the new benzodiazepines (a class of drug that includes Valium, Librium, Klonopine). Talk Radio News Service

Eco Fest Vision Starts to Take Shape  -  ‎Apr 1, 2009‎
Debbie Plopper, special projects manager for Conway Sanitation, said "Eco-Librium" is a key word for the event because the planners want to present all KATV

Overhaul of services after teacher's death  -  ‎Mar 30, 2009‎
The inquest heard that Miss Owen had suffered mental health problems with anxiety and depression and was treated with the drug librium for two years. Grimsby Telegraph

What is Generalized Anxiety Disorder?  -  ‎Apr 18, 2009‎
Antidepressants, such as Paxil and Effexor XR, benzodiazepines, such as Ativan, Xanax, Librium, Klonopin, and Valium, beta-blockers, and busparine may all Examiner.com

GARDEN ROUTE NEWSPAPER  -  ‎Apr 9, 2009‎
Please note that the next qualifier will be held at Equine-Librium on May 16. Shoprite Checkers has pledged R10 000 towards the NSRI Awareness Campaign, CXpress

Depression Linked to Drugs Commonly Given to ICU Patients  -  ‎Apr 13, 2009‎
Benzodiazepine drugs, which include Xanax (alprazolam), Librium (chlordiazepoxide), Valium (diazepam), and Ativan (lorazepam), are frequently prescribed to Natural News.com

Check out the weekend sport offerings  -  ‎Apr 9, 2009‎
...and Jerry Yester of the Lovin' Spoonful. Columbian Theatre, Wamego. Live music Evolution of Pain, Librium, Blood In The Wire and Balldozer, 8 pm PJ's Pub. Manhattan Mercury

Court reports  -  ‎Apr 2, 2009‎
Jordan said she had taken two Librium pills, and consumed vodka and beer. At Chambersburg Hospital pills in her purse were identified as Xanax. Echo Pilot

Too Good to Be True  -  ‎Apr 1, 2009‎
The FDA found that the Brazilian diet pills also contained active ingredients also found in Librium, used to alleviate anxiety, and Prozac, Newsweek

Robyn Hitchcock's new album 'is a masterpiece'  -  ‎Apr 4, 2009‎
...while TLC seems like a love song which lopes along before the cat is out of the bag when he sings the chorus line "Triptisol, Librium, Carbatrol". Daily Gleaner

Optimism brews, but the bad news bubbles away  -  ‎Apr 1, 2009‎
Is Starbucks slipping Librium into its Pike Place Blend? How does anyone look at the latest numbers and think things are looking up? The National

Why I blame myself for the murder of Sixties playwright Joe Orton ...  -  ‎Apr 3, 2009‎
...'He's on valium, librium, speed, Nembutal and every other pill he can lay hands on. It's making him unbearable. 'I know I've got to leave him. Daily Mail

La mariguana y la hipocresía de los legisladores  -  ‎Apr 16, 2009‎
La legalización de las drogas, es decir, su venta controlada en farmacias, como es el caso de las benzodiacepinas (Xanax, Tafil, Lexotan, Librium, Risolid, La Jornada (México)

El consumo de tabaco y drogas se dispara entre los jóvenes con ...  -  ‎Apr 7, 2009‎
...cuatro grupos: marihuana (cannabis o hachís), estimulantes (cocaína, crack, anfetaminas o speed), opiáceos, heroína y tranquilizantes (Valium, Librium. Faro de Vigo

You See Obammas Tech Guru Gets Locked up  -  ‎Mar 13, 2009‎
With this kind of manic episode, I would think Librium might be a more effective management tool. GO AWAY!! and bother MiddleClassBill he seems to like it. TPMCafé

Your Life: Why Is Trying To Keep Fit Such A Pain?  -  ‎Mar 14, 2009‎
If you have been drinking every day, you will need a detox with a benzodiazepine, such as Librium, and vitamins. To keep you sober, there is a medication Glasgow Sunday Mail

Withdrawal symptoms can vary  -  ‎Mar 3, 2009‎
Other drugs in this class are clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan) and chlordiazepoxide (Librium). I'm not sure I would use the word Times Daily

March 2009 Mayo Clinic Health Letter Highlights Knee Repair ...  -  ‎Mar 10, 2009‎
Drugs in this category include alprazolam (Xanax), chlordiazepoxide (Librium), clonazepam (Klonopin), diazepam (Valium) and lorazepam (Ativan). PR Newswire (press release)

Prescribing practices called into question  -  ‎Feb 23, 2009‎
By the mid-1980s, there were 17 benzodiazepines on the market, including Librium and Valium, but it has since been found that regular use leads to loss of Irish Times

Research points to increased drug use among Travellers  -  ‎Mar 5, 2009‎
...alcohol with benzodiazepines (psychoactive prescribed drugs such as Valium, Mogadon and Librium); benzodiazepines with Solpadeine; Solpadeine with Waterford Today

NJ-based Roche shedding more than 1500 jobs in Genentech deal  -  ‎Mar 12, 2009‎
...a business it later moved to Warren County -- and then returned to making medicines, including widely-used tranquilizers such as Librium and Valium. The Star-Ledger - NJ.com

Four at Four: Banks Get Blasted — Again  -  ‎Feb 19, 2009‎
Please cut your Martini intake to 12 a day and lay off those square polka dot darcoset/librium combo pills. Whoa Nellie. Introduction. Wall Street Journal Blogs

1%Club kondigt eigenzinnige decemberacties aan  -  ‎Mar 15, 2009‎
NogHarder.nl (animatie), Mechanicus.nl (montage), ScreamingScreen.com (sound), Palookaville, ON, Librium, Mia Media, Reality Outdoor en Minima Fair. HappyNews

Opvallende uitslag (on) gewenste intimiteiten enquete  -  ‎Mar 4, 2009‎
HDC Media, Holland Combinatie, Basismedia, Telegraaf Tijdschriften Groep, WebRegio Media, Pilarczyk Mediagroep, Telegraaf Productiehuis en Librium TV. Ezpress (persbericht)

Dover man claims 'pathological intoxication' in deaths of Kinnelon ...  -  Jan 28, 2009
Authorities have said that Baum was drunk on vodka, under the influence of the anti-anxiety drug Librium, and driving on the road shoulder when he allegedly Dailyrecord.com,

To Cut Costs, GM May Stop Making Cars  -  Jan 30, 2009
Why don't you just take away my Librium too and I can just curl up into a ball and cry until I dehydrate to death?" Hurwitz also noted that you don't have Crystal Air Productions (satire),

Toronto paramedic tells all: The Emergency Monologues  -  Feb 2, 2009
Celexa, Prozac, Zoloft, Effexor, Wellbutrin, Thorazine, Haldol, Zyprexa, Seroquel, Risperdal, Lithium, Tegretol, Ritalin, Valium, Librium, Antabuse… National Post,

Our most anxious times  -  Jan 24, 2009
Tone's thoughtful, engaging book focuses on the development and phenomenal success of tranquilizers like Miltown, Valium and Librium during the 1950s and The Gazette (Montreal),

Police blotter - January 14, 2009  -  Jan 13, 2009
Police allegedly found 83.8 grams of marijuana, 23 Librium pills and firearms Coley is not allowed to possess because of prior convictions, accoording to Fort Mills Times,

What About Pain Pills and Similar Medications?  -  Jan 17, 2009
Valium, Xanax, Ativan, Librium, Paxipam, Restoril, Serax, Tranxene, and Centrax are older versions of medications often prescribed to resolve all kinds of NewsReleaseWire.com (press release)

Waking Up from the American Dream, 1950s Style  -  Jan 9, 2009
...life of the stay-at-home mom are painted neatly into this film until the its hard-core undertow drowns away the bunny-and-rainbow-Librium fifties fog. Huffington Post,

Narrowcasting Spits in trams GVB (Amsterdam)  -  Jan 23, 2009
De marketing en sales van het kanaal wordt door Librium.TV gedaan. In samenwerking met Librium.TV produceert Sp!ts voor dit kanaal het actuele nieuws en DigitaalMedia,

John van Rooy: de beste allround student van Nederland  -  Feb 3, 2009
Holland Combinatie, Basismedia, Telegraaf Tijdschriften Groep, WebRegio Media, Pilarczyk Mediagroep, Telegraaf Productiehuis, Librium TV en 402EVENTS. Nieuwsbank (persbericht) (abonnement),

Daten in het donker groot succes  -  Jan 20, 2009
HDC Media, Holland Combinatie, Basismedia, Telegraaf Tijdschriften Groep, Pilarczyk Mediagroep, Telegraaf Productiehuis, WebRegio Media en Librium TV. Nieuwsbank (persbericht) (abonnement),

Distributie én narrowcasting Sp!ts bij McDonald's  -  Jan 19, 2009
HDC Media, Holland Combinatie, BasisMedia, Telegraaf Tijdschriften Groep, WebRegio Media, Pilarczyk Mediagroep, Telegraaf Productiehuis en Librium TV. Nieuwsbank (persbericht) (abonnement),

Psicofarmaci responsabili della violenta morte di Maria Borghini?  -  Jan 10, 2009
Alcuni nomi in commercio sono: Frisium, Transene, En, Librium, Psicofar, Reliberan, Seren Vita, Madar, Madar Notte, Aliseum, Ansiolin, Eridan, Noan, Nopsych,

Brand Names/Synonyms:
Librium is also known by the following brand names and/or synonymsA-Poxide; Abboxide; Apo-Chlordiazepoxide; Balance; CD 2; CDO; CDP; Chloradiazepoxide; Chlordiazachel; Chlordiazepoxid; Chlordiazepoxide; Chlordiazepoxide Base; Chlordiazepoxide Hcl; Chlordiazepoxidum; Chloridazepoxide; Chloridiazepide; Chloridiazepoxide; Chlorodiazepoxide; Chlozepid; Clopoxide; Clordiazepossido; Contol; Control; Decacil; Eden; Elenium; Helogaphen; Ifibrium; Kalmocaps; Librax; Librelease; Librinin; Libritabs; Librium; Limbitrol; Limbitrol Ds; Lygen; Menrium; Mesural; Methaminodiazepoxide; Mildmen; Multum; Napoton; Napton; Novo-Poxide; Psicosan; Radepur; Risolid; Silibrin; Tropium; Viopsicol

Drug Category:
Librium is categorized under the following by the FDA: Anti-anxiety Agents; Hypnotics and Sedatives; Adjuvants, Anesthesia; Benzodiazepines; GABA Modulators; ATC:N05BA02

Dosage Forms:
CAPSULE (5 mg, 10 mg or 25 mg)

Absorption:
Not Available

Interactions:
Interactions for Chlordiazepoxide: Although clinical studies have not established a cause and effect relationship, physicians should be aware that variable effects an blood coagulation have been reported very rarely in patients receiving oral anticoagulants and chlordiazepoxide. The concomitant use of alcohol or other central nervous system depressants may have an additive effect.



Chemical IUPAC Name:
10-chloro-3-hydroxy-N-methyl-2-phenyl-3,6-diazabicyclo[5.4.0]undeca-1,6,8,10-tetraen-5-imine

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