Lamisil

This page contains recent news articles, when available, and an overview of Lamisil but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Lamisil
(when available)

Pharmacology and use:
Terbinafine is an allylamine antifungal agent and acts by inhibiting squalene epoxidase, thus blocking the biosynthesis of ergosterol, an essential component of fungal cell membranes. in vitro, mammalian squalene epoxidase is only inhibited at higher (4000 fold) concentrations than is needed for inhibition of the dermatophyte enzyme. Depending on the concentration of the drug and the fungal species test in vitro, Terbinafine may be fungicidal. However, the clinical significance of in vitro data is unknown. For the treatment of interdigital tinea infections

Mechanism Of Action:
Terbinafine is hypothesized to act by inhibiting squalene epoxidase, thus blocking the biosynthesis of ergosterol, an essential component of fungal cell membranes.

News Articles on Terbinafine

Digger's baaaack: Toenail monster returns  -  ‎Aug 6, 2009‎
But seriously, Lamisil was the only thing that worked on my fungus. 3 months of Lamisil, another 6 months for the nails to grow out, and for the first time msnbc.com

Laser leads the way  -  ‎Aug 20, 2009‎
Previously, the best-known cure for the fungus, which affects up to 10 percent of Americans (most of them 70 or older), was Lamisil—but the pill is Chico News & Review

Herb Benham: Going toe to toe with nail fungus  -  ‎Aug 6, 2009‎
Another friend used Lamisil (liver damage is a slight risk) and for a couple of years had toenails that were so pretty he could have entered them in the Bakersfield Californian

Doctor receives bribes for prescribing drugs  -  ‎Aug 4, 2009‎
Jugova told the fake dealer that she advised her patients to ask for Lamisil in pharmacies instead of the cheaper Terbinafin that she was ordered to Prague Daily Monitor

Rite Aid launches video site for OTC coupons  -  ‎Aug 7, 2009‎
...providing coupons for a variety of OTC products, including seven dollars off Wyeth's Centrum Ultra, and one dollar off Novartis's Lamisil, for example. Medical Marketing and Media

Voltaren y Lamisil se acercan al público  -  ‎Aug 24, 2009‎
Durante 3 días, los representantes de los productos Voltaren y Lamisil compartirán con los asistentes diversas actividades, entre ellas sesiones gratuitas El Carabobeño

ExpoVida llegará en septiembre a la Universidad Metropolitana  -  ‎Aug 21, 2009‎
Entre los expositores, que durante tres días ofrecerán información a los visitantes, se encuentra Voltaren y Lamisil de Laboratorios Novartis, El Universal (Venezuela)

BrnÄ›nská lékaÅ™ka brala roky úplatky  -  ‎Aug 4, 2009‎
Tolik si brala lékařka Eliška Jugová za každý recept, na kterém pacientům předepsala lék Lamisil. Metody dermatoložky z Fakultní nemocnice u svaté Anny v denik.cz

LékaÅ™ka brala úplatky. Případ už Å™eší policie i ÄŒLK  -  ‎Aug 7, 2009‎
Å lo o přípravek Lamisil proti kožním plísním. Doktorka si tak vydÄ›lala až deset tisíc korun mÄ›síÄ?nÄ› nad rámec svého platu. KromÄ› toho si údajnÄ› nechávala Aktuálně.cz

LékaÅ™ Hnízdil: I já jsem pÅ™edepisoval léky, které pacienti ...  -  ‎Aug 4, 2009‎
...ruky," pÅ™iznává se ve skryté kameÅ™e Jugová ženÄ›, která se vydávala za zástupkyni spoleÄ?nosti Novartis a pÅ™emlouvala ji k vÄ›tšímu užívání léku Lamisil. iHNed.cz

LékaÅ™ka placená farmaceutickou firmou dostala výpovÄ›Ä?  -  ‎Aug 6, 2009‎
Za každého pacienta, kterému pÅ™edepsala jejich lék Lamisil, dostala prý 250 korun. PÅ™iÅ¡la si tak mÄ›síÄ?nÄ› asi na deset tisíc korun. Firma Novartis ale tvrdí, ČT24

LékaÅ™ka, kterou odměňoval výrobce léků, Ä?elí trestnímu oznámení  -  ‎Aug 7, 2009‎
Novartis do skryté kamery Å™ekla, že za každého pacienta, který se mÄ›l půl roku léÄ?it přípravkem Lamisil proti plísním, dostávala 250 korun mÄ›síÄ?nÄ›. Novinky

Ärztebestechung schlägt Wellen  -  ‎Aug 6, 2009‎
Für jeden Patienten, der Lamisil verordnet bekam, zahlte demnach der schweizerische Pharmakonzern Novartis 250 Kronen (umgerechnet rund neun Euro). apotheke-adhoc

ë°œ ë²—ê³  ë°œ 관리 나서면 '맨발ì?˜ 계절' ì?´ ì¦?ê²?다  -  ‎Aug 10, 2009‎
...무좀ì?„ 치료하는 í•­ì§„ê·  로션ì?´ë‚˜ 파우ë?”, 연고로는 털비나핀(Terbinafine, 브랜드명 Lamisil), í?´ë¡œíŠ¸ë¦¬ë§ˆì¡¸(Clotrimazole, 브랜드명 Lotrimin), 미주 한국일보

Po aféře s úplatky se lékaÅ™i fakultní nemocnice nesmí bavit s firmami  -  ‎Aug 7, 2009‎
...kteří se vydávali za zástupce farmaceutické firmy Novartis, pÅ™iznala, že za každého pacienta, který se půl roku léÄ?il přípravkem Lamisil proti plísním, iDNES.cz

LékaÅ™ku už vyÅ¡etÅ™uje komora  -  ‎Aug 6, 2009‎
...v jedné chvíli pÅ™estal platit, pÅ™eÅ¡la ke konkurenÄ?ní firmÄ› Actavis, která vyrábí lék Terbinafin Actavis se stejnou léÄ?ivou látkou, jako má Lamisil. Hospodářské noviny

Dem Pilz den Garaus machen  -  ‎Aug 11, 2009‎
..."Mykotika" sind klassische Pilz-Medikamente wie "Lamisil One", die rezeptfrei in der Apotheke erhältlich sind. Der Nachteil: Die Medikamente helfen oft nur Lippische Landes-Zeitung

Fußpilz effektiv behandeln  -  ‎Aug 10, 2009‎
Der indirekte, das heißt rechnerische Wirksamkeitsvergleich ergab, dass die Terbinafin-Einmalanwendung (Lamisil® Once) beispielsweise vergleichbar wirksam Springer Gesundheit und Pharmazie

De slag om de patiënt  -  13 Jul 2009
Novartis produceert het middel Lamisil (terbinafine) tegen schimmel- of kalknagels. Dat is doorgaans een cosmetisch probleem. Tot voor enkele jaren was het Knack

Athlete's Foot: How Do You Know If You Have Athlete's Foot?  -  ‎Jul 7, 2009‎
...water The second part of the treatment involves buying easily obtainable over the counter applications such as clotrimazole, Lamisil and ketoconazole. Nurido

Lamisil: даешь открытую обувь!  -  ‎Jun 18, 2009‎
Как Ñ?ледует из примеров, креаторы подходÑ?Ñ‚ к рекламе противогрибкового Ñ?редÑ?тва Lamisil (Ламизил) от фармацевтичеÑ?кой швейцарÑ?кой компании «Ð?овартиÑ? Ð?Г» Ñ? Sostav.ru

O afectiune careia “ii placeâ€? vara  -  ‎Jul 2, 2009‎
Odata evidentiata ciuperca si pus diagnosticul tratamentul poate fi zonal cu creme (ketoconazol (Nizoral), clotrimazol (Lotrimin), terbinafina (Lamisil), Healthy.ro

ã€?元氣藥學堂】藥物導致「味覺喪失ã€?,讓人食ä¸?知味?  -  ‎Jul 2, 2009‎
...高雄榮總藥劑部藥師毛志民 記得媒體曾報導一女å­?æœ?用治療ç?°æŒ‡ç”²è—¥Terbinafine(Lamisil)一個月後導致味覺喪失,並以å?°ç?£ã€Œé¦–例ã€?ã€?「罕見ã€?為新è?žæ¨™é¡Œï¼Œæ??醒民眾注æ„?。 康健雜誌

People's Pharmacy: Magnesium supplements carry risks  -  ‎Apr 19, 2009‎
Q: My husband has toenail fungus, and our podiatrist prescribed a 30-day supply of Lamisil pills. They cost hundreds of dollars. There were no guarantees it Houston Chronicle

Lamisil: Salesmanship Over Science  -  ‎Apr 7, 2009‎
Lamisil, a drug used to treat toenail fungus, has been linked to 16 cases of liver failure, including 11 deaths. Yet despite this risk, Lamisil is a big Newsinferno.com

DR. BETSY NEAHRING: Use patience, persistence in treating ...  -  ‎Apr 12, 2009‎
Athlete's foot can generally be treated successfully with an over-the-counter cream like Lotrimin or Lamisil. Apply the cream to the affected area once or Evansville Courier & Press

Mets closing up in 'Port St. Laboratory'  -  ‎Apr 1, 2009‎
So acknowledging that poetic license was at work -- because athlete's foot was not the issue -- we named the camp Port St. Lamisil. MLB.com

Aurobindo gets first approval from Swissmedic for BPH drug  -  ‎Apr 7, 2009‎
Terbinafine is the generic equivalent of Novartis Pharmaceutical Canada Inc's Lamisil tablets, indicated for the treatment of fungal infections of the skin Business Standard

Beat Your 5 Workout Woes With These Easy Tips  -  ‎Apr 8, 2009‎
Treat It - Over-the-counter Lamisil AT Cream ($16; drugstore.com) can reduce the symptoms within several days. Prevent It - Wearing flip-flops in gym New York's CW11 / WPIX-TV

WFLV zeigt Wege zu den Geldtöpfen  -  ‎Apr 7, 2009‎
Er suchte gemeinsam mit dem Arzneimittelkonzern Norvatis, der sein Fußpflegeprodukt Lamisil ins Gespräch bringen wollte, die dreckigste Kabine Deutschlands Derwesten.de

ИнформациÑ? о побочных Ñ?ффектах лекарÑ?тв решает их Ñ?удьбу  -  ‎Mar 30, 2009‎
противогрибковые мази ("Lamisil" компании Novartis AG), контрацептивы ("Plan B" компании "Teva Pharmaceutical Industries") и другие, которые продаютÑ?Ñ? и ИИА. Ремедиум

Οι μυκητιάσεις των ποδιών ταλαιπωÏ?οÏ?ν το 15% του πληθυσμοÏ?  -  ‎Apr 8, 2009‎
Η νέα θεÏ?απεία με τεÏ?βιναφίνη (lamisil once) εμφανίζει εντυπωσιακά αποτελέσματα, καθώς εφαÏ?μόζεται μία φοÏ?ά και απομακÏ?Ï?νει κάθε δυσφοÏ?ία και ενόχληση και Ιατροnet

W!LDBRAIN Animation Studios News  -  18 Mar 2009
The studios' previous experience in computer animation ranges from the preschool animated series Higglytown Heroes and assorted commercial work for Lamisil Animation Insider

Dr. Chris Milkie: Milwaukee foot doctor first in Wisconsin to ...  -  ‎Feb 20, 2009‎
...of the disease and the pervasive television advertisements for Lamisil (http://www.youtube.com/watch?v=WI9J7MoBZbY), an oral anti-fungal medication. Wisbusiness.com

Ranbaxy gets TGA-Australia`s nod for SEBIFIN Terbinafine Tablets  -  ‎Mar 6, 2009‎
...and having the same therapeutic effect as that of the reference listed product, Lamisil tablets of Novartis Pharmaceutical Australia (P). Myiris.com

Forest, Cypress postpone fibromyalgia drug launch; Microsoft teams ...  -  ‎Mar 6, 2009‎
Report > Ranbaxy Laboratories got Australian regulatory approval to sell its version of the Novartis antifungal treatment Lamisil. FiercePharma

NovaBay Pharmaceuticals Announces Lead Anti-infective Product ...  -  ‎Mar 7, 2009‎
...based on an established animal model previously used in the preclinical evaluation of terbinafine (Lamisil(R)) and itraconazole (Sporanox(R)). PR Newswire (press release)

W!LDBRAIN Animation Powerhouse Expands Operations to Los Angeles  -  ‎Mar 4, 2009‎
...companies such as Smith & Tinker and continues to produce award-winning commercial animation work for long time clients, including Esurance and Lamisil. PR Newswire (press release)

Closing Bell  -  ‎Mar 6, 2009‎
The Ranbaxy formulation of Terbinafine is bioequivalent to and having the same therapeutic effect as that of the reference listed product, Lamisil Tablets, Economic Times

10 Questions With Kevin Blackistone  -  ‎Feb 26, 2009‎
We use Rogaine for our thinning hair, Prozac for depression, Xanax for anxiety, Prilosec for heartburn, Lamisil for toenail fungus, Viagra for fun, RealClearSports

Dangerous medicines in drugstores  -  ‎Mar 10, 2009‎
Medicine for losing the weight Xenical (Roche Holding AG) may lead to bleeding, Lamisil (made by Swiss pharmaceutical company Novartis AG), MIGnews.com.ua

Pondering pampering and pedicures  -  ‎Feb 23, 2009‎
The only treatment I ever gave them was a dose of Lamisil AT for a harsh case of athlete’s foot. The lady went to work. I didn’t get her name. The Charlatan

Athlete's foot common  -  ‎Feb 23, 2009‎
Lamisil Film Forming Solution is the only single dose treatment available against athlete's foot. Wash your feet at least once a day, more frequently if iAfrica.com

Ranbaxy Gets TGA-Australia Approval For Sebifin® Terbinafine  -  ‎Mar 10, 2009‎
...having the same therapeutic effect as that of the reference listed product, Lamisil® Tablets of Novartis Pharmaceuticals Australia Pty Ltd, Australia. Pharmaceutical Online (press release)

A 9. hét legnézettebb reklámfilmjei  -  ‎Mar 10, 2009‎
A Teva Magyarország például Neogranormon termékét támogatja a 11. helyre bekerült szpottal, míg a Novartis részérÅ‘l a Lamisil reklámja kapott helyet a Média Infó

Минздрав готовит "черный" Ñ?пиÑ?ок медицинÑ?ких препаратов  -  ‎Mar 12, 2009‎
Lamisil (швейцарÑ?кой фармкомпании Novartis AG) - противогрибковаÑ? мазь (выÑ?окий риÑ?к пÑ?ихичеÑ?ких раÑ?Ñ?тройÑ?тв), Diovan (Novartis AG), препарат, Версии.сом

Минздрав Ñ?оÑ?тавлÑ?ет "черный" Ñ?пиÑ?ок лекарÑ?тв  -  ‎Mar 9, 2009‎
..."Lamisil" (швейцарÑ?кой фармкомпании "Novartis AG") - противогрибковаÑ? мазь (выÑ?окий риÑ?к пÑ?ихичеÑ?ких раÑ?Ñ?тройÑ?тв), "Diovan" ("Novartis AG"), препарат, ЛІГА.Новости

Terbinafin: Leitlinienerweiterung vorgestellt  -  ‎Mar 9, 2009‎
Im Januar 2009 wurde nun auch die Terbinafin-Einmalanwendung (Lamisil® Once) in die Empfehlungen mit aufgenommen. Die Autoren begründen ihre Entscheidung Springer Gesundheit und Pharmazie

US FDA lists drugs under review for safety issues  -  04 Feb 2009
N) nail fungus treatment Lamisil and Roche's malaria drug Lariam, both for the risk of psychiatric events. Agency officials are also looking at Novartis' Reuters

Lamisil without prescription  -  Jan 17, 2009
Related nicole codeine way much phentermine lamisil without prescription lamisil without prescription lamisil without prescription lamisil without Griggs County Courier,

Lamisil pharmacy  -  Jan 17, 2009
Watch 5 lamisil pharmacy from people the give much home without mail to from particular lamisil pharmacy work Dizziness internet adipex adipex not NAISD. Griggs County Courier,

Lamisil pills  -  Jan 17, 2009
However with xanax not. lamisil pills lamisil pills occur Difficulty lamisil pills violate simply of to sufferers can sexual to sexual Alzheimer's and Griggs County Courier,

What treatments work for athlete's foot?  -  Jan 21, 2009
Terbinafine cream or spray: The brand name for terbinafine cream or spray is Lamisil. You can get it on prescription from your doctor, or you can buy it guardian.co.uk,

Aurobindo terbinafine approval- what effect will this have?  -  Jan 21, 2009
Implications: This article is important in that it confirms another terbinafine competitor to the Novartis Lamisil brand is being released. Gerson Lehrman Group,

Old Governor's Mansion revitalization approved  -  Jan 15, 2009
Retreat Plaza pharmacy filled a prescription for 200 milligrams of Lamisil, which treats toenail infections, with 200 milligrams of Lamictal instead. Kentucky.com,

Fungal nail infections  -  Jan 21, 2009
The tablets that doctors use most often are called itraconazole (brand name Sporanox) and terbinafine (Lamisil). Terbinafine seems to work slightly better. guardian.co.uk,

Terbinafine tablets  -  Jan 21, 2009
The brand name is Lamisil. You need a prescription from your doctor to get this medicine. About 13 in 20 people who take terbinafine tablets for six weeks guardian.co.uk,

What treatments work for fungal nail infections?  -  Jan 21, 2009
Terbinafine tablets (brand name Lamisil): These are antifungal tablets. They treat nail infections caused by a fungus. More... Fluconazole tablets (brand guardian.co.uk,

Manhattan Research Releases Top Pharma Brand Product Sites by ...  -  Feb 3, 2009
Crestor, Cymbalta, Depakote, Depo-Provera, Detrol LA, Effexor XR, Enbrel, Flomax, Flonase, Flovent, Fosamax, Gardasil, Humira, Imitrex, Lamisil, Lantus, PR Web (press release),

THIS JUST IN: Monongalia County  -  Jan 9, 2009
She intended to write a prescription for Lamisil, an anti fungal medication. Instead, Kelly wrote the prescription for Lamictal, an anti-seizure medication. West Virginia Record,

Woman sues over alleged medication error: Core Health Care, Giant ...  -  Jan 11, 2009
25, 2007, to seek treatment for nail fungus. She was examined by Kelly, who, intending to give her Lamisil for the fungus, erroneously prescribed Therapeutics Daily (press release) (registration),

Athlete's foot  -  Jan 21, 2009
The brand name is Lamisil. You might get a mild rash or itching when you use this cream or spray. This will go away when you stop treatment. guardian.co.uk,

Woman files suit after being prescribed wrong medication  -  Jan 21, 2009
After Dr. Kay Kelly examined Rose's nails, she prescribed Rose 250 mg of Lamictal, an anti-seizure medication, instead of the anti-fungal medication Lamisil West Virginia Record,

Aurobindo Pharma gets Canada nod for terbinafine  -  Dec 23, 2008
VX: Quote, Profile, Research) Lamisil indicated for the treatment of fungal infections in the skin and nails, the company said in a statement. Reuters India,

Woman struggles after medicine makes her sick  -  Dec 23, 2008
She walked out with a prescription for Lamisil, a drug that caused an adverse reaction in her system and caused the soles of her feet and hands to swell up, Royal Gazette,

Market Live  -  Dec 24, 2008
Terbinafine tablets is the generic equivalent of Novartis Pharmaceutical Canada Inc's lamisil tablets 125 mg and 250 mg, which is indicated for the Economic Times,

'En Dan Nu Het Roer Om'  -  Dec 14, 2008
Het nieuwe jaar is nog niet begonnen of ze zit nu al met een begrotingstekort, ze koopt zich nog steeds blauw aan Lamisil en Tryptizol én ze zit verlegen om Sterrennieuws,

Brand Names/Synonyms:
Lamisil is also known by the following brand names and/or synonymsBramazil; Lamasil; Lamisil; Lamisil At; Terbina; Terbinafine; Terbinafine Hcl; Terbinafine Hydrochloride; Ternbinafine Hcl

Drug Category:
Lamisil is categorized under the following by the FDA: Trypanocidal Agents; Antifungals; Allylamines; ATC:D01AE15; ATC:D01BA02

Dosage Forms:
TABLET; CREAM; SPRAY

Absorption:
Readily absorbed from gastrointestinal tract.

Interactions:
-->Interactions for Terbinafine:

In vitro studies with human liver microsomes showed that terbinafine does not inhibit the metabolism of tolbutamide, ethinylestradiol, ethoxycoumarin, and cyclosporine. In vitro studies have also shown that terbinafine inhibits CYP2D6-mediated metabolism. This may be of clinical relevance for compounds predominantly metabolized by this enzyme, such as tricyclic antidepressants, ß-blockers, selective serotonin reuptake inhibitors (SSRIs), and monoamine oxidase inhibitors (MAO-Is) Type B, if they have a narrow therapeutic window.

In vivo drug-drug interaction studies conducted in normal volunteer subjects showed that terbinafine does not affect the clearance of antipyrine or digoxin. Terbinafine decreases the clearance of caffeine by 19%. Terbinafine increases the clearance of cyclosporine by 15%.

There have been spontaneous reports of increase or decrease in prothrombin times in patients concomitantly taking oral terbinafine and warfarin, however, a causal relationship between LAMISIL® Tablets and these changes has not been established.

Terbinafine clearance is increased 100% by rifampin, a CyP450 enzyme inducer, and decreased 33% by cimetidine, a CyP450 enzyme inhibitor. Terbinafine clearance is unaffected by cyclosporine.

There is no information available from adequate drug-drug interaction studies with the following classes of drugs: oral contraceptives, hormone replacement therapies, hypoglycemics, theophyllines, phenytoins, thiazide diuretics, beta blockers, and calcium channel blockers.





Chemical IUPAC Name:
N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine

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