Inderal

This page contains recent news articles, when available, and an overview of Inderal but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Inderal
(when available)

Pharmacology and use:
Propranolol, the prototype of the beta-adrenergic receptor antagonists, is a competitive, nonselective beta-blocker similar to nadolol without intrinsic sympathomimetic activity. Propanolol is a racemic compound; the l-isomer is responsible for adrenergic blocking activity. For the prophylaxis of migraine

Mechanism Of Action:
Like atenolol and metoprolol, propranolol competes with sympathomimetic neurotransmitters such as catecholamines for binding at beta(1)-adrenergic receptors in the heart and vascular smooth muscle, inhibiting sympathetic stimulation. This results in a reduction in resting heart rate, cardiac output, systolic and diastolic blood pressure, and reflex orthostatic hypotension. Higher doses of atenolol also competitively block beta(2)-adrenergic responses in the bronchial and vascular smooth muscles.

News Articles on Propranolol

Senator Hillary Clinton Visits Akrimax Pharmaceutical Plant in ...  -  Aug 5, 2008
Akrimax currently markets the Inderal Family and LoOvral branded products and operates the Rouses Point manufacturing facility in conjunction with Wyeth MarketWatch

MMA and Mental Health  -  Jul 21, 2008
The blood pressure drug Inderal is one that has been used successfully in the past, even on teenagers having this problem. One of the reasons that so many Bleacher Report,

Most e-mailed stories  -  Jul 9, 2008
Medicines such as propranolol (Inderal) and primidone (Mysoline) often can control the shaking, and there are others. Botox can be injected to abolish the Fort Worth Star Telegram,

Dr. Paul Donohue  -  Jul 9, 2008
Medicines such as propranolol (Inderal) and primidone (Mysoline) often can control the shaking, and there are others. You can get in touch with the DetNews.com,

NAFDAC alerts the nation to fake anti-hypertension drugs  -  Jul 24, 2008
...has alerted the nation to the circulation of fake and substandard anti-hypertension drugs known as Propranolol or Inderal in the market. The Punch,

Police briefs: Cops find cocaine in Broadway apartment  -  Jul 31, 2008
25.5 Inderal, two Flexeril, nine Glynase Prestab, 26 Adderall, 11 Elavil and an assortment of undetermined pills, including 10 small white tablets, Cambridge Chronicle,

Pharmacologic Management of Multiple Sclerosis  -  Jul 23, 2008
Additional symptomatic treatment may include clonazepam (Klonopin(R)) and propranolol (Inderal(R)) for ataxia and tremors; baclofen (Lioresal(R)), RedOrbit,

BUYINS.NET: (WYE) SqueezeTrigger Price is $44.892. There is ...  -  Jul 23, 2008
...cardiovascular products, including ALTACE (co-promoted with King Pharmaceuticals, Inc.) and INDERAL; nutrition products, including 3RD AGE PROGRESS; Trading Markets (press release),

Popular Drugs, Side-Effects and Feeling Ill  -  Jul 1, 2008
Beta-blockers, such as propranolol (Inderal), atenolol (Tenormin), betaxolol (Betoptic S), carteolol (Cartrol) and labetalol (Normodyne), are commonly Rocklin and Roseville Today,

Blood Pressure Medications Can Multi-Task  -  Jun 30, 2008
Popular ones include metoprolol (Lopressor/Toprol), atenolol (Tenormin) and propranolol (Inderal). The side effects are lengthy, including dry mouth, Best of Times,

Drug Development Needs Private Industry  -  Jun 27, 2008
Beta blockers such as Inderal (propranolol) and Toprol (metroprolol), which treat angina, hypertension and related conditions, are another example. Wall Street Journal

A Shopper's Guide To Memory  -  Jun 27, 2008
In addition a variety of medicines can affect your memory such as Valium, Ativan, Inderal, Halcion, Sonata, and Ambien. Those are the causes listed by the Evening Bulletin,

Migraine headache often under-diagnosed and under-treated?  -  Jun 20, 2008
Propranolol (Inderal) often is used first, provided that the patient does not have asthma, COPD or heart disease. • Preventive medications are begun at low Cameroon Radio Television,

Just one more to calm the nerves ...  -  Jun 4, 2008
On the subway in New York in 1986, I took my first dose of Inderal, a beta blocker, some 45 minutes before an audition. It seemed miraculous. guardian.co.uk,

BUYINS.NET: (WYE) SqueezeTrigger Price is $44.287. There is ...  -  Jun 17, 2008
...cardiovascular products, including ALTACE (co-promoted with King Pharmaceuticals, Inc.) and INDERAL; nutrition products, including 3RD AGE PROGRESS; Trading Markets (press release),

Medication not always the answer when it comes to high blood pressure  -  May 20, 2008
Inderal? Cardizem? Or will she suggest you put into action a do-it-yourself lifestyle program? In some cases, the do-it-yourself path might be the right one Daily News Transcript,

Betting on beta blockers  -  May 13, 2008
Propranolol (Inderal), the first drug in the class, was developed in the late 1950s. Many others have come along since, including atenolol (Tenormin), Gather.com,

Ask OSNews: Use of Brain-Boosting Drugs in the Software Industry?  -  Apr 10, 2008
One in five Nature readers -- mostly scientists -- say they up their mental performance with drugs such as Ritalin, Provigil, and Inderal. [. OS News

BUYINS.NET: (WYE) SqueezeTrigger Price is $43.778. There is ...  -  May 28, 2008
...cardiovascular products, including ALTACE (co-promoted with King Pharmaceuticals, Inc.) and INDERAL; nutrition products, including 3RD AGE PROGRESS; Trading Markets (press release),

Wyeth Q1 2008 Earnings Call Transcript  -  23 Apr 2008
As we expected, our primary engines for revenue growth Inderal, Prevnar and nutritionals continued their strong performance. It's fair to know that we also Seeking Alpha,

Many Scientists Using Performance Enhancing Drugs  -  Apr 10, 2008
Among the drug-using population, 62% used Ritalin, 44% used Provigil, and 15% used beta-blockers like Inderal. Frequency of use was evenly divided among Slashdot

Poll: Scientists Use Brain-Boosting Drugs  -  Apr 9, 2008
Beta-blockers, such as Inderal, accounted for 15% of the drug use. Most respondents said they took the drugs to improve concentration or to improve focus WebMD

Typical of the world today  -  Apr 10, 2008
...by deathshadow (2.32) on Fri 11th Apr 2008 05:41 UTC I would question this just because of the drugs listed... particularly Inderal which is a SEDATIVE and Newmobilecomputing.com

Pick-me-up pill to boost brain  -  Apr 20, 2008
Anecdotal evidence suggests as many as three in four classical musicians in the US take beta blockers such as Inderal, which block adrenalin receptors in Independent Online,

Forest Labs' Race Against the Clock  -  Apr 16, 2008
...versions of Wyeth's (NYSE: WYE) Inderal and GlaxoSmithKline's (NYSE: GSK) Coreg. That spending should pay off if it leads to a decent prescription base. Motley Fool

Ask OSNews: Use of Brain-Boosting Drugs in the Software Industry?  -  Apr 10, 2008
One in five Nature readers -- mostly scientists -- say they up their mental performance with drugs such as Ritalin, Provigil, and Inderal. [. OS News

Eurand's formulations stack up at the FDA  -  11 Mar 2008
...without physician approval) of Inderal LA, which is a long-acting version of propanolol indicated for the treatment of hypertension and migraines. In-PharmaTechnologist.com,

Wrong Medicine Given To 5 Year Old Boy Triggers Harder Look At ...  -  Feb 12, 2008
...mistakenly gave the parents of a five-year-old child Methitest, a steroid for older males, while Trey Jones instead needed Inderal to control tremors. AHN

Speed contributes to pharmaceutical errors  -  Mar 9, 2008
Trey's hands continued to shake, so his doctor doubled the initial 10-milligram dose of Inderal. Walgreens again misfilled the prescription, this time with New Brunswick Home News Tribune,

Drug-Food Interactions  -  Mar 8, 2008
Avoid drinking alcohol with propranolol, sold as Inderal, because the combination lowers blood pressure too much. Nitrates (nitroglycerin, etc. Council Bluffs Daily Nonpareil,

New test shows source of disease side-effects  -  Feb 24, 2008
Propranolol is a so-called beta blocker drug sold by Wyeth under the brand name Inderal and also available generically. "That was a bit of a surprise," Scientific American

New Study Explains Side Effects of Popular Cholesterol Drugs  -  Feb 25, 2008
Propranolol, made by Wyeth and sold under the name Inderal, is a beta blocker drug and is also available generically. Other drugs that resembled statins RedOrbit,

Probing Mitochondria for Statin Myopathy Mystery  -  Feb 25, 2008
...wasn't seen with other statins, although it was seen with another drug often used by the same patients - the beta-blocker propranolol (Inderal). MedPage Today,

Akrimax Pharmaceuticals Announces New President  -  Feb 25, 2008
Akrimax currently markets Inderal LA and LoOvral branded products and operates the Rouses Point manufacturing facility in conjunction with Wyeth during a Trading Markets (press release),

Hong Kong Biotech Company Presents Satisfactory Clinical Results  -  Feb 25, 2008
Comparing to the name brand propranolol (Inderal), our sublingual propranolol demonstrated significantly better in pharmacokinetic parameters. NewsBlaze (press release),

Help available for migraines  -  Feb 4, 2008
Dooley took one Inderal LA pill each day. “I didn’t like it,� she recalled. “It made me extremely tired. I could barely get out of bed in the morning. Bloomington Pantagraph,

Pumping up your brain with legal drugs  -  Jan 27, 2008
...also includes Ritalin, commonly given to schoolchildren for attention deficit hyperactivity disorder, and beta blockers, such as the heart drug Inderal. Baltimore Sun,

Wyeth Q4 Profit Up On Strong Drug Sales  -  Jan 31, 2008
The rise in Pharmaceuticals net revenue was offset, in part, by lower sales of Inderal LA due to generic competition. Alliance revenue fell 13% to $321 RTT News,

Wyeth Reports Earnings Results for the 2007 Fourth Quarter and ...  -  Jan 31, 2008
The increase in Pharmaceuticals net revenue was offset, in part, by lower sales of Inderal(R) LA due to generic competition. Alliance revenue decreased 13% PR Newswire (press release),

Conquer Your Public Speaking Jitters  -  Jan 19, 2008
BY WYLACOT AT 11/05/07 10:19 PM If your MD approves it, see if you can get a scrip for a low dose of propranolol (a beta blocker, common trade name Inderal) Lifehacker,

Wyeth plant rescued by new start-up firm  -  Jan 16, 2008
Products currently on its books include Inderal (propanolol) tablets and long-acting capsules, and Lo Ovral (ethinyl estradiol and norgestrel). In-PharmaTechnologist.com,

NY pharmaceutical plant finds a buyer  -  Jan 16, 2008
Akrimax, which has some Vermont roots, has purchased the rights from Wyeth to produce Inderal, a beta-blocker drug, and a few oral contraceptives from Wyeth BurlingtonFreePress.com,

Wyeth acquisition finalized  -  Jan 16, 2008
The company has also acquired Wyeth patents associated with its beta-blocking drug Inderal, as well as the contraceptives Ovral and Lo Ovral. Plattsburgh Press Republican,

The next generation of coffee  -  Jan 11, 2008
In particular, some classical musicians use inderal, a drug that blocks the effects of adrenaline. Sarah Tuck, a classical musician, told the LA Times that Calvin College - Chimes,

BUYINS.NET: (WYE) SqueezeTrigger Price is $47.721. There is ...  -  Jan 9, 2008
...cardiovascular products, including ALTACE (co-promoted with King Pharmaceuticals, Inc.) and INDERAL; nutrition products, including 3RD AGE PROGRESS; Trading Markets (press release),

Medication caution for asthmatics  -  Nov 8, 2007
Beta blockers including propranolol (Inderal), atenolol (Tenormin) and metoprolol (Lopressor, Toprol), are drugs used to control blood pressure, PRESS TV,

The Women Who Care For Us All Won't Care for cvs's Sappy Spot  -  Oct 28, 2007
Does this have anything to do with your local purveyor of Rolaids, folding lawn chairs and Inderal? But CVS knows that the woman who buys the Band-Aids and AdAge.com (subscription)

Dr. Gott: Gluten might cause bowel problems  -  Oct 18, 2007
I was taken off of lisinopril and put on Inderal, and I still have this chronic cough every day. I am using an Advair inhaler for a 60-day round. Northwest Herald,

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...cardiovascular products, including ALTACE (co-promoted with King Pharmaceuticals, Inc.) and INDERAL; nutrition products, including 3RD AGE PROGRESS; Trading Markets (press release),

BUYINS.NET: (WYE) squeezetrigger Price is $46.959. There is ...  -  Oct 23, 2007
...cardiovascular products, including ALTACE (co-promoted with King Pharmaceuticals, Inc.) and INDERAL; nutrition products, including 3RD AGE PROGRESS; Trading Markets (press release),

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Peyronie's disease and abnormally bent penis - causes, symptoms ...  -  Oct 1, 2007
Peyronie's disease is sometimes a side effect of the drug Inderal (propanolol) used against high blood pressure. Sometimes a physical injury to the penis SkyNewswire.com (press release),

Buy Drugs Without Prescription. Safe and Secure Ordering.  -  Oct 3, 2007
...buspar cheap, buspar adverse effects, buspar and inderal difference, buspar common side effects, change cardizem from short acting to long acting, LIVE-Wintersport.com,

Boy's eye problem is no one's fault  -  Oct 8, 2007
If his headaches come often, preventive medicines should be considered. They don't stop a headache once it has started. They can ward them off. Inderal and Roanoke Times,

BUYINS.NET: (WYE) SqueezeTrigger Price is $46.970. There is ...  -  Oct 4, 2007
...cardiovascular products, including ALTACE (co-promoted with King Pharmaceuticals, Inc.) and INDERAL; nutrition products, including 3RD AGE PROGRESS; Trading Markets (press release),

Actavis' generic Inderal LA gets US approval  -  Aug 14, 2007
The Actavis product is the generic equivalent of Wyeth Pharmaceuticals' Inderal LA capsules and available in 60mg, 80mg, 120mg and 160mg dosage strengths. Therapeutics Daily (subscription) (press release),

Actavis Receives Approval Generic Inderal(R) LA Capsules in the US  -  Aug 13, 2007
Propranolol Hydrochloride extended-release (ER) capsules are the generic equivalent of Wyeth Pharmaceuticals' Inderal(R) LA capsules and available in 60mg, Earthtimes.org

Calling it down the stretch  -  Aug 12, 2007
Durkin, the announcer at Saratoga Race Course for the past 17 years, has in the past resorted to hypnosis and Inderal, a beta-blocker, to calm his nerves. Glens Falls Post-Star,

Pharma Sector: Few Newsmakers Of The Week - Icagen, ArGentis ...  -  Aug 18, 2007
Inderal, a type of medication known as a beta blocker, is used in the treatment of high blood pressure, angina pectoris (chest pain, usually caused by lack Trading Markets,

Men's : Peyronie's disease and abnormally bent penis - causes ...  -  Sep 1, 2007
Peyronie's disease is sometimes a side effect of the drug Inderal (propanolol) used against high blood pressure. Sometimes a physical injury to the penis Prudent Press Agency (press release),

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What causes canker sores?  -  Aug 2, 2007
DetNews.com,Examples are Inderal, Normodyne, Corgard, Lopressor and Tenormin. You can make your own mouthwash to ease the pain and promote healing.

Eurand Reports First Half 2007 Key Achievements and Financial Results  -  Aug 3, 2007
CNNMoney.comEurand has developed an AB-rated generic to Inderal LA, licensed to Reliant Pharmaceuticals, for the treatment of hypertension and migraines.

Wyeth Q2 Profit Increases; Adj. EPS Tops Consensus; Raises FY07 ...  -  Jul 19, 2007
Trading Markets,The increase in Pharmaceuticals net revenue was offset in part by lower sales of Zoton and Inderal LA due to generic competition.

Brand Names/Synonyms:
Inderal is also known by the following brand names and/or synonymsAngilol; Apsolol; Avlocardyl; Bedranol; Beprane; Berkolol; Beta-Neg; Beta-Propranolol; Beta-Tablinen; Beta-Timelets; Betachron; Betalong; Cardinol; Caridolol; Corpendol; Deralin; Dl-Propranolol Hydrochloride; Dociton; Duranol; Efektolol; Elbrol; Etalong; Euprovasin; Frekven; Inderal; Inderal La; Inderide; Indobloc; Innopran Xl; Intermigran; Kemi S; Obsidan; Oposim; Prano-Puren; Propanalol; Propanix; Propanolol; Prophylux; Propranalol; Propranolol; Propranolol Hcl; Propranolol Hcl Intensol; Propranolol Hydrochloride; Propranur; Proprasylyt; Pylapron; R,S-Propranolol Hydrochloride; Rapynogen; Reducor; Reducor Line; Sagittol; Servanolol; Sloprolol; Sumial; Tesnol

Drug Category:
Inderal is categorized under the following by the FDA: Vasodilator Agents; Anti-anxiety Agents; Antihypertensive Agents; Antiarrhythmic Agents; Adrenergic Agents; ATC:C07AA05

Dosage Forms:
Tablets, I.V.

Absorption:
Propranolol is almost completely absorbed from the GI tract; however, plasma concentrations attained are quite variable among individuals

Interactions:
Interactions for Propranolol:

Patients receiving catecholamine-depleting drugs such as reserpine should be closely observed if Propranolol HCl is administered. The added catecholamine-blocking action may produce an excessive reduction of resting sympathetic nervous activity, which may result in hypotension, marked bradycardia, vertigo, syncopal attacks, or orthostatic hypotension.

Caution should be exercised when patients receiving a beta blocker are administered a calcium-channel blocking drug, especially intravenous verapamil, for both agents may depress myocardial contractility or atrioventricular conduction. On rare occasions, the concomitant intravenous use of a beta blocker and verapamil has resulted in serious adverse reactions, especially in patients with severe cardiomyopathy, congestive heart failure, or recent myocardial infarction.

Blunting of the antihypertensive effect of beta-adrenoceptor blocking agents by nonsteroidal anti-inflammatory drugs has been reported.

Hypotension and cardiac arrest have been reported with the concomitant use of propranolol and haloperidol.

Aluminum hydroxide gel: Greatly reduces intestinal absorption of propranolol.

Ethanol: Slows the rate of absorption of propranolol.

Phenytoin, phenobarbitone: and rifampin accelerate propranolol clearance.

Chlorpromazine: When used concomitantly with propranolol, results in increased plasma levels of both drugs.

Antipyrine: and lidocaine have reduced clearance when used concomitantly with propranolol.

Thyroxine: May result in a lower than expected T3 concentration when used concomitantly with propranolol.

Cimetidine Decreases the hepatic metabolism of propranolol, delaying elimination and incre:asing blood levels.

Theophylline: Clearance is reduced when used concomitantly with propranolol.





Chemical IUPAC Name:
1-(1-methylethylamino)-3-naphthalen-1-yloxy-propan-2-ol

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