Hydroxyzine

This page contains recent news articles, when available, and an overview of Hydroxyzine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Hydroxyzine
(when available)

Pharmacology and use:
Hydroxyzine, a piperazine antihistamine structurally related to buclizine, cyclizine, and meclizine, is used to treat histamine-mediated pruritus or pruritus due to allergy, nausea and vomiting, and, in combination with an opiate agonist, anxiolytic pain. Hydroxyzine is also used as a perioperative sedative and anxiolytic and to manage acute alcohol withdrawal. Hydroxyzine's active metabolite, cetirizine, is also used as an H1-antagonist. For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria.

Mechanism Of Action:
Hydroxyzine competes with histamine for binding at H1-receptor sites on the effector cell surface, resulting in suppression of histaminic edema, flare, and pruritus. The sedative properties of hydroxyzine occur at the subcortical level of the CNS. Secondary to its central anticholinergic actions, hydroxyzine may be effective as an antiemetic.

News Articles on Hydroxyzine

Researchers probe allergy treatments in horses  -  ‎Aug 28, 2009‎
Hydroxyzine limited the response for only three days. Neither treatment had any effect on the blood test results at any time. Allergic diseases in horses Horsetalk

Tattooing may solve missing nose pigment  -  ‎Aug 20, 2009‎
She was given hydroxyzine (25 mg) to take several times a day, but I prefer not to medicate her and especially not that much. Our answer is to not give her Norman Transcript

The Register-Guard  -  ‎Aug 7, 2009‎
Among them were the antidepressant amitriptyline; the anti-anxiety drug hydroxyzine; the anti-insomnia drug zolpidem; the narcotic pain medication oxycodone The Register-Guard

Pain Management in Acute Care  -  13 Jul 2009
Hydroxyzine or promethazine may add to the analgesic effect of an opioid while promoting relaxation and decreasing the incidence of nausea and vomiting. ADVANCE for LPNs

Unichem gets USFDA nod for allergy drugs  -  ‎Jun 30, 2009‎
Cetirizine hydrochloride an antihistamine, is a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist used in the treatment Myiris.com

Novel Kinase Inhibitor Shows Promise in RA  -  ‎Jun 26, 2009‎
...including corticosteroids -- as long as doses were low and stable -- nonsteroidal anti-inflammatory drugs, and hydroxyzine or prednisolone for skin MedPage Today

Wolves ruling harmful  -  ‎Apr 16, 2009‎
We have tried half an adult portion of Benadryl and then Hydroxyzine (25 mg., twice a day) for itching, as she bites her back feet. In-Forum

Certains aliments me causent des problèmes. Qu'est-ce que je fais ?  -  ‎Apr 1, 2009‎
Pour les cas de réactions allergiques plus légères, des antihistaminiques sous forme de comprimés (par ex. diphenhydramine, hydroxyzine et cétirizine) Canoë

Best Practices: An Intervention to Promote Evidence-Based ...  -  ‎Feb 27, 2009‎
...in quetiapine use, including chlorpromazine, clonazepam, diphenhydramine, haloperidol, hydroxyzine, lorazepam, temazepam, trazodone, and zaleplon. Psychiatric Services (subscription)

Roselle Park man evades Kenilworth police; assaults officer after ...  -  ‎Mar 5, 2009‎
Cruz, who was found to have Hydroxyzine Pamoate, an anti-anxiety medication, and Seroquel, an anti-psychotic medication in his possession, was charged with Cranford Chronicle - NJ.com

What's the evidence for hydroxyzine?  -  Jan 21, 2009
The research on hydroxyzine is reasonably good. We found one good study and a review that included details of another two studies involving more than 700 guardian.co.uk,

When Is a Headache Over?  -  Feb 2, 2009
Double-blind, multicenter trial to compare the efficacy of intramuscular dihydroergotamine plus hydroxyzine versus intramuscular meperidine plus hydroxyzine Medscape

What's the evidence for buspirone?  -  Jan 21, 2009
...[1] We're less sure how buspirone compares with other drug treatments such as benzodiazepines, antidepressants or hydroxyzine. guardian.co.uk,

How anxiety disorder is treated  -  Jan 21, 2009
To learn more about one of these drugs, see Hydroxyzine. Support and advice about how you can help yourself. For example, your GP may put you in touch with guardian.co.uk,

Cutaneous Mastocytosis. Getting beneath the skinof the issue: a ...  -  Jan 20, 2009
The child received symptomatic relief with chronic oral hydroxyzine and ranitidine therapy. Automated epinephrine self-injectors usually prescribed in this 7thSpace Interactive (press release),

만성질환 ë…¸ì?¸ 50% "ë‚´ê°€ 먹는 약 몰ë?¼"  -  Dec 23, 2008
...만성 �드러기나 가려움� 치료� �히 쓰�는 약� 항히스타민 계열� '하�드�시진(hydroxyzine)'� 1명� 부�절한 처방� 받았다. � 약� 변비, 입마름, 뉴스플러스,

Gold Medal Lockdown  -  Nov 19, 2008
...often overlooked: Even if DeMont gained some pharmacological effect from ephedrine, Hollinger writes that Marax also contains hydroxyzine--"which would Tucson Weekly,

Wolters Kluwer Health Expands Tall Man Drug Name Lettering in Medi ...  -  Nov 17, 2008
Hydroxyzine) where Tall Man lettering is recommended. Many manufacturers also utilize Tall Man drug names in their labeling to further reduce the potential Business Wire (press release),

Dog with allergies has odor  -  Nov 7, 2008
The doctor prescribed hydroxyzine first to treat the allergies, and then prednisone when they returned. Now, I am using pramoxine spray on him and his DetNews.com,

Editorial - Treatment of Bladder Pain Syndrome/Interstitial ...  -  Oct 5, 2008
Only oral pentosan polysulfate sodium, amitriptyline, hydroxyzine, and cyclosporine A reach a high level of recommendation based on clinical trial evidence. UroToday,

Exercise-induced hives can be a long-term problem  -  Sep 30, 2008
Antihistamines (particularly hydroxyzine) can help symptoms, but they might not prevent a severe attack. Cholinergic urticaria is also known as Orlando Sentinel,

Doctor faces charge on improper distribution of drugs  -  Oct 1, 2008
Lorazepam, Ketamine, Hydroxyzine, Demerol and Dilaudid were removed from Cosby's trailer, which was in "deplorable condition," according to the criminal Susquehanna Independent,

Authorities rule death of Holton teen accidental  -  Sep 29, 2008
...levothyroxine, a thyroid hormone synthetic; cyclobenzaprine, a muscle relaxant; hydroxyzine, an antihistamine; plus hydrocodone (Vicodin) and methadone. Muskegon Chronicle - MLive.com,

Suspect arrested for visiting mom  -  Sep 1, 2008
...deliberately playing loud music. Police reports said two hydroxyzine hydrochloride pills were found on the suspect, and no prescription bottle was found. Monroe News Star,

Interstitial Cystitis And Pelvic Pain Syndromes  -  07 Aug 2008
Oral drugs are beneficial in treatment of IC/PBS/BPS- amitriptyline, the synthetic GAG sodium pentosanpolysulfate (Elmiron), the anti-histamine Hydroxyzine Medical News Today (press release),

Preventing Errors at the Pharmacy  -  Aug 6, 2008
Hairer said, “There is a drug called hydalazine to treat blood pressure, and there's a drug called hydroxyzine, which can be used to treat itching and some 13WHAM-TV,

Treatment Modalities, Health Care Resource Utilization, and Costs ...  -  Jul 28, 2008
Physician visits were fewest among patients treated with pentosan polysulfate sodium plus amitriptyline and hydroxyzine. Physician visits were higher for UroToday,

Man arrested with 9-year-old daughter in tow  -  Jul 9, 2008
...at around 3:50 pm on June 30, after police found a hypodermic syringe and a bottle of purple-colored pills believed to be Hydroxyzine in his pocket. South End News,

Aspen now Colorado outlet for a controversial new addiction treatment  -  Aug 3, 2008
A combination of three drugs (flumazenil, hydroxyzine, and gabapentin), nutritional therapy, and psycho-social counseling, the Prometa treatment program was Aspen Times,

Drug traffickers thwart police and Customs as demand grows  -  Jul 29, 2008
The most common additives are boric acid, which is used as an antiseptic, pro-caine, used to ease pain, hydroxyzine, to treat anxiety, and tetramisole, Times Online,

General Practitioners Prescribing Potentially Inappropriate ...  -  Jul 18, 2008
Dr. Mychaskiw noted that long-acting benzodiazepines, hydroxyzine, and some short-acting benzodiazepines and tricyclic antidepressants at high doses have DG News

Sun Pharma`s arm gets approval for Hydroxyzine hydrochloride tablets  -  Jun 16, 2008
Sun Pharmaceutical Industries` US subsidiary received final approval from the US Food and Drug Administration (USFDA), for Hydroxyzine hydrochloride tablets Myiris.com,

Beyond the Abstract - Treatment of Bladder Pain Syndrome ...  -  Jun 9, 2008
...amitriptyline and hydroxyzine treatment, and immunologic abnormalities, supported by good responses to cyclosporine A and again support for hydroxyzine. UroToday,

People With Dementia Should Avoid Certain Drugs  -  Jun 27, 2008
Cyproheptadine (Periactin), Dexchlorpheniramine (Polaramine), Diphenhydramine (Benadryl or Sominex), Hydroxyzine (Atarax), Phenindamine (Nolahist), RedOrbit,

Mother sentenced to 35 years in prison for son's death  -  May 22, 2008
A toxicologist testified Tuesday that a blood sample taken from the infant's body during an autopsy showed hydroxyzine levels about six times the expected Beaufort Gazette,

Toxicologist claims mother killed son trying to quiet him with ...  -  May 20, 2008
Up to 17 extra dosages of doctor-prescribed anti-itch medication, Atarax or hydroxyzine, were given to Ra'Saan Cortez Avery Young, who was found dead at a Beaufort Gazette,

Look-alike drug names tempt fate  -  May 9, 2008
The former was a trade name for hydroxyzine, an antihistamine. The latter is the name for raloxifene, a selective estrogen receptor modulator, National Review of Medicine,

Budesonide/Formoterol Pressured Metered Dose Better Than Either ...  -  May 23, 2008
...nebulised albuterol, systemic or topical corticosteroids, hydroxyzine, beta-blockers, or hydrocortisone at a concentration >1%. DG News

Sobriety in a Bottle  -  May 21, 2008
The other Prometa drugs are gabapentin, which goes by the brand name Neurontin and was approved to treat epilepsy and to control seizures, and hydroxyzine, Broward New Times,

City passes on ‘unproven’ drug treatment program  -  Apr 19, 2008
Prometa is a combination of three medications — Flumazenil, Hydroxyzine and Gabapentin — independently approved by the Food and Drug Administration. Federal Way Mirror,

Rejigged, ready  -  Apr 3, 2008
...tablets (used to treat pain or inflammation caused by arthritis) and Hydroxyzine Hydrochloride tablets (for treatment of anxiety) in the US market. Sify,

Hospitals Work To Correct Medication Inaccuracies  -  Mar 24, 2008
He gave examples of two similiar-sounding and similar-spelled medications: HyDROXYzine, a medication for motion sickness and HyDRALAzine, for high blood Tampa Tribune,

Spiro Anderson, 14, died after taking others' prescription ...  -  Mar 6, 2008
...levothyroxine, a thyroid hormone synthetic; cyclobenzaprine, a muscle relaxant; hydroxyzine, an antihistamine; plus hydrocodone (Vicodin) and methadone. MLive.com,

Psychotic Symptoms Following Buprenorphine Withdrawal  -  Mar 3, 2008
Hydroxyzine, 150 mg/day, and loxapine, 100 mg/day, resulted in substantial symptom reduction, and buprenorphine was further decreased by 2 mg/day. Am J Psychiatry (subscription)

Don't let hives stop you from exercising  -  Jan 22, 2008
Antihistamines (particularly hydroxyzine) may help symptoms, but they may not prevent a severe attack. Cholinergic urticaria is also known as heat-induced Times Daily (subscription),

Drug experts tackle trouble with medication names  -  Feb 4, 2008
...[hydralazine and hydroxyzine] come in 10 milligrams and 25 milligrams. And on most pharmacy shelves, they'll be very close to each other. Newsday,

Texas' Prometa program for treating meth addicts draws skeptics  -  Jan 20, 2008
How it works: Patients receive one drug – flumazenil – intravenously, and two others – hydroxyzine and gabapentin – orally. None of the drugs, Dallas Morning News,

Setbacks plague drug addiction remedy  -  Jan 11, 2008
Hythiam doesn't own or produce the three drugs used in the treatment – gabapentin, flumazenil and hydroxyzine -- but claims ownership of a proprietary MSNBC

Wendy Ann Satmary, MD, Kaiser Permanente Medical Center, Woodland ...  -  Jan 30, 2008
Nighttime scratching can be effectively treated with a sedating antihistamine (eg, hydroxyzine [Vistaril]) given two hours before bedtime.22 The dose can be AAFP News Now

Church of Scientology statement  -  Jan 15, 2008
As the oxicology report clearly states: “ Trace of Hydroxyzine (Vistaril).� A “trace of� is not “full of� (and as the toxicology report clearly provides, MSNBC

Drug addicts find hope  -  Nov 16, 2007
The treatment protocol is a combination of three medications — Flumazenil, Hydroxyzine and Gabapentin — that have been independently approved by the Food Federal Way Mirror,

Pseudo : Mot de passe :  -  Nov 9, 2007
Recent Searches Truvada Carisoprodol Elavil Alprazolam Namenda Combunox Hydroxyzine Amoxicillin on line casinos Xenical Metronidazole Top 10 mg-yellow, Journal lycéen,

Overproduction of blood cells can provoke an intolerable itch  -  Oct 20, 2007
Diphenhydramine (Benadryl), hydroxyzine (Vistaril) and cyproheptadine (Periactin) are examples of good anti-itch antihistamines. DEAR DR. SouthCoastToday.com,

Medical examiner: Immigrant died from cocaine, hydroxyzine  -  Sep 19, 2007
7 while in federal custody in Rhode Island, died of "acute intoxication" from the combined effects of cocaine and hydroxyzine, a medication used to treat Boston Globe,

Brazilian man who died in custody had cocaine, medicine in system  -  Sep 19, 2007
...of "acute intoxication" caused by a combination in his system of cocaine and hydroxyzine, a medication normally used to treat anxiety and vomiting. Fort Wayne Journal Gazette,

Pharmacologic Management of Painful Bladder Syndrome/Interstitial ...  -  Oct 8, 2007
Hydroxyzine, intravesical bacille Calmette-Guérin, and resiniferatoxin therapy failed to demonstrate efficacy, but evidence was inconclusive owing to Archives of Internal Medicine

Wal-Mart Launches Phase Two of Prescription Program With New $4 ...  -  Sep 27, 2007
HALOPERIDOL 0.5MG QTY 30 HALOPERIDOL 1MG QTY 30 HALOPERIDOL 2MG QTY 30 HALOPERIDOL 5MG QTY 30 HYDROXYZINE HCL10MG/5ML SYRUP QTY 120ML LITHIUM CARBONATE CNNMoney.com

Sedation Dentistry May Help Allay All your Dental Fears  -  Sep 25, 2007
Some the most commonly used drugs to sedate dental patients are triazolam, diazepam (Valium), lorazepam (Ativan) zaleoplon (Sonata) and hydroxyzine PR-GB.com (press release),

Milford man who died in ICE custody had cocaine in system  -  Sep 19, 2007
..."The cause of death," Gilson wrote, "has been determined to be acute intoxication due to the combined effects of cocaine and hydroxyzine (a medication used Milford Daily News,

Immigrant died of drug combination  -  Sep 19, 2007
...was caused by “acute intoxication� — a combination of the effects of cocaine and hydroxyzine, a medication used for treating anxiety and vomiting. Providence Journal (subscription),

29 diabetes, asthma drugs banned  -  Sep 2, 2007
On June 9, the board barred pharmaceutical firms from marketing these drugs because they contained Theophylline, Ephedrine HCL, Hydroxyzine and Gatifloxacin Daily Times,

Puppy mills booming thanks to ads on Web  -  Sep 3, 2007
The next several years were filled with frequent visits to veterinarians, special baths, benadryl and hydroxyzine and even acupuncture. MaineToday.com,

Management of insomnia: treatments and mechanismsi  -  Aug 31, 2007
More profound effects on sleep have been reported for both promethazine and hydroxyzine, although neither is available over the counter and they have quite British Journal of Psychiatry (subscription),

Ways to live with interstitial cystitis  -  Aug 30, 2007
Hydroxyzine (Atarax), an antihistamine-like prescription medication, also has helped some IC sufferers. Some people with IC find relief with bladder Myrtle Beach Sun News,

The Invasion Begins  -  Aug 28, 2007
Vistaril is the brand name of Hydroxyzine, an anti-anxiety medication. I almost hate telling Ron Baginski that, in the end, even Hubbard needed some psych Cleveland Free Times,

Sleepless in Childhood  -  Aug 2, 2007
Ivanhoe,About a third of the kids who received a sleep prescription were given antihistamines, like hydroxyzine (Atarax), while another 26 percent were prescribed

Study Finds Kids Often Prescribed Drugs for Insomnia  -  Aug 4, 2007
Earthtimes.org...was recommended for 12 percent, and mental health and stress management therapy for 7 percent, but 81% were prescribed drugs including hydroxyzine.

Kids often get unapproved drugs for sleep problems  -  Aug 1, 2007
Scientific AmericanThis included an antihistamine, such as hydroxyzine, in 33 percent; sedative drugs, known as alpha-2 agonists, in 26 percent; benzodiazepines,

Brand Names/Synonyms:
Hydroxyzine is also known by the following brand names and/or synonymsAlamon; Atara; Atarax; Atarax Base; Ataraxoid; Atarazoid; Atarox; Atazina; Aterax; CHEMBANK2612; Deinait; Durrax; Equipoise; Equipose; Fenarol; HSDB 3098; Hidroxizina [Inn-Spanish]; Hy-Pam 25; Hychotine; Hydroksyzyny; Hydroksyzyny [Polish]; Hydroxine; Hydroxizine; Hydroxizinum; Hydroxycine; Hydroxyzin; Hydroxyzine; Hydroxyzine Base; Hydroxyzine Hcl; Hydroxyzine Pamoate; Hydroxyzinum [Inn-Latin]; Hydroxyzyne; Idrossizina; Idrossizina [Dcit]; Masmoran; NP 212; Neo-Calma; Neurozina; Nevrolaks; Orgatrax; Pamazone; Parenteral; Paxistil; Placidol; Plaxidol; Quiess; Tran-Q; Tranquizine; Traquizine; U.C.B 4492; U.CB 4492; UCB 4492; UCB 492; UCB-4492; Vesparaz-Wirkstoff; Vistaril; Vistaril Pamoate; Vistazine

Drug Category:
Hydroxyzine is categorized under the following by the FDA: Antipruritics; Histamine H1 Antagonists; Anxiolytics sedatives and hypnotics; ATC:N05BB01

Dosage Forms:
CAPSULE; LIQUID; SOLUTION; SYRUP

Absorption:
Rapidly absorbed from the gastrointestinal tract

Interactions:
Interactions for Hydroxyzine:

THE POTENTIATING ACTION OF HYDROXYZINE MUST BE CONSIDERED WHEN THE DRUG IS USED IN CONJUNCTION WITH CENTRAL NERVOUS SYSTEM DEPRESSANTS SUCH AS NARCOTICS, NON-NARCOTIC ANALGESICS AND BARBITURATES. Therefore when central nervous system depressants are administered concomitantly with hydroxyzine their dosage should be reduced.

Since drowsiness may occur with use of this drug, patients should be warned of this possibility and cautioned against driving a car or operating dangerous machinery while taking Atarax. Patients should be advised against the simultaneous use of other CNS depressant drugs, and cautioned that the effect of alcohol may be increased.





Chemical IUPAC Name:
2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]ethanol

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