Flexeril

This page contains recent news articles, when available, and an overview of Flexeril but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Flexeril
(when available)

Pharmacology and use:
Cyclobenzaprine, closely related to the antidepressant amitriptyline, is used as a skeletal muscle relaxant to reduce pain and tenderness to and improve mobility. Unlike dantrolene, cyclobenzaprine cannot be used to treat muscle spasm secondary to cerebral or spinal cord disease. For use as an adjunct to rest and physical therapy for relief of muscle spasm associated with acute, painful musculoskeletal conditions

Mechanism Of Action:
Like the tricyclic antidepressants, cyclobenzaprine exhibits anticholinergic activity, potentiation of norepinephrine, and antagonism of reserpine. Cyclobenzaprine does not directly act on the neuromuscular junction or the muscle but relieves muscle spasms through a central action, possibly at the brain stem level. Cyclobenzaprine binds to the serotonin receptor and is considered a 5-HT2 receptor antagonist that reduces muscle tone by decreasing the activity of descending serotonergic neurons.

News Articles on Cyclobenzaprine

St. Landry Parish - The St. Landry Parish Sheriff's Office ...  -  ‎Apr 19, 2009‎
...possession with intent to distribute prescription drugs, two counts of distribution of Flexeril without a prescription and two counts of contributing to Opelousas Daily World

Domestic dispute leads to drugs, weapons charges  -  ‎Feb 19, 2009‎
Police confiscated Vicodin, Lorcet, Flexeril, Didrex, Suboxone, Klonopin, Adipex and Demerol allegedly belonging to Toups from the safe. Daily Comet

Fatal overdose of 18-year-old newlywed in Sharon ruled accidental  -  ‎Feb 19, 2009‎
Flexeril, a muscle relaxer; Unisom, an antihistamine with sedative effects; the painkillers Tramadol and Ultram; and the anti-depressant Zoloft. Sharon Herald

Persistent pain? Find help in traditional and nontraditional ...  -  ‎Mar 4, 2009‎
For Cynthia's fibromyalgia, she takes Flexeril, a muscle relaxant, and the sleep medicine nortriptyline because the lack of sleep and pain are related. PennLive.com

Eight pounds of pot seized  -  ‎Feb 19, 2009‎
Other criminal complaints charge Dilernia with possessing three prescription pills -- a Percocet, a Lortab and a Flexeril. She did not have a prescription Huntington Herald Dispatch

NP woman arrested for helping teen escape state custody  -  ‎Feb 25, 2009‎
She said Turnbull smuggled cigarettes and Flexeril, a muscle relaxing drug, into the facility for her son. After Clark-Guthrie was caught with the North Platte Bulletin

Worcester Superior Court  -  ‎Feb 21, 2009‎
...charged with possession of marijuana, found responsible, fined $100; possession of cocaine, possession of Flexeril, and possession of sulfamethoxazole, Worcester Telegram

3 Bottles of Pills in the Car, 3 Bottles of Pills...  -  Feb 3, 2009
A bottle of Zolpidem prescribed to another individual and a bottle containing suspected Flexeril with no label attached. In addition to the arrest warrant Bay Net,

St. Mary's County Sheriff's Reports  -  Feb 2, 2009
A bottle of Zolpidem prescribed to another individual and a bottle containing suspected Flexeril with no label attached. In addition to the arrest warrant Southern Maryland Online,

Written by Administrator  -  Jan 16, 2009
The pills later were identified as Vicodin, Percocet and Flexeril, and no prescriptions were turned in, according to the report. Pembroke Express,

Suicide Ambien Flexeril  -  Dec 11, 2008
Down an Suicide Ambien Flexeril level of unscrupulous marketing. Spinal cord and it needle. Dre slightly uncomfortable, but Suicide Ambien Flexeril open Granada digital,

Soma 350 Flexeril  -  Dec 11, 2008
Homes internet surveillance an Soma 350 Flexeril. Drug with electrocardiography ecg, and results every test may sacrifice. Transducer across state pharmacy Granada digital,

Married couple fight back against addiction  -  Dec 13, 2008
Her doctor prescribed Darvocet, Tylenol 3, Vicodin and Flexeril for her pain. She’d stop taking the pills, but after giving birth to her second child, Wilkes Barre Times-Leader,

Many Drugs Not Well Suited For The Elderly  -  Dec 4, 2008
Muscle relaxants such as Robaxin or Flexeril “are very sedating and can increase the risk of falls,� Dr. Salamon notes. The important thing to remember is Boston Channel.com,

Father Uses Two Young Sons in Attempted Burglary  -  Nov 16, 2008
...with second-degree burglary, first-degree theft and two counts of illegal possession of the drugs Clonazepam and Flexeril in the attempted burglary. FOXNews

Arrest log from the week of Nov. 3, 2008  -  Nov 3, 2008
...he allegedly discovered the stubs of several marijuana joints in the car’s ashtray and a single Flexeril pill, a muscle relaxant in an empty cigarette case. Arlington Advocate,

Back Pain - Medication for Back Pain  -  Nov 6, 2008
Muscle relaxes are sold under the trade names of Flexeril, Soma, Valium, and others. These medications help to relieve muscle spasm, but may also make ireport

Worcester Central District Court  -  Nov 5, 2008
...found responsible, filed; possession of Viagra, possession of Xanax, possession of Motrin, possession of Flexeril, and driving negligently, dismissed. Worcester Telegram,

Adieu, Rimonabant  -  Nov 3, 2008
...and physical therapists, and prescribed Celebrex, Flexeril, Soma, Valium, Vicodin, Percodan, Percocet, Darvocet, Ultram, ibuprofen, naproxen, etc. CounterPunch,

First Aid for Fractures While Mountain Biking  -  Oct 18, 2008
If anyone has muscle relaxants (Valium, Flexeril, etc.) or painkillers (Demerol, ibuprofen, etc.), now would be a good time to administer them. MountainZone.com,

Aurobindo Pharma gets USFDA nod for two drugs  -  Oct 10, 2008
Cyclobenzaprine is a generic version of MCNEIL -PPC's Flexeril tablets and are indicated to be used for relief of muscle spasm. The two approvals take the Hindu,

Traffic stop leads to multiple charges for Cotton Valley man  -  Oct 15, 2008
During the booking process, Hudson was searched and found to have six Lortab and five and one-half Flexeril pills in his possession. KTBS,

Market Live  -  Oct 10, 2008
Cyclobenzaprine hydrochloride tablets is the generic version of MCNEIL-PPC’s Flexeril tablets 5mg and 10mg and is indicated as an adjunct for relief of Economic Times,

Soldier training at Fort Irwin died due to prescription drug ...  -  Aug 20, 2008
...night before her death that her medication had been stolen and her doctor had given her morphine and a muscle relaxer called Flexeril as replacements. Desert Dispatch,

Blotter: Accident kills one, injures one in Shreveport  -  Aug 27, 2008
A search of his vehicle led to the discovery of opened bottles of alcoholic beverages and a pill bottle containing one Skelaxin tablet, two Flexeril tablets Shreveport Times,

Joseph Valdez's Last Year  -  Aug 2, 2008
He obtains a prescription for the muscle relaxer Flexeril. May 18: He visits a pain clinic, complaining of back pain. May 22: He obtains the painkiller Tampa Tribune,

Elmore County Sheriff's Office investigates firearm thefts  -  Aug 6, 2008
A suspect was found with 54 Lortab 10mg, 30 Flexeril 10mg and 30 Keflex 10 mg. Theft: A Stihl saw valued at $875.46 was taken from a property located at the Prattville Progress,

Rookie cop arrested for second time  -  Jul 14, 2008
Marketed under the brand name Flexeril and Fexmid, cyclobenzaprine is commonly prescribed for chronic back and neck pain and is potentially addictive. The Times of Trenton - NJ.com,

Growing abuse of drug sale laws need to be curbed, not ignored  -  Jul 14, 2008
Schedule III and IV drugs such as Ambien, a habit-forming sleeping pill, or Flexeril, a muscle relaxer, are still for sale on these sites. UI The Daily Iowan (subscription),

Police briefs: Cops find cocaine in Broadway apartment  -  Jul 31, 2008
25.5 Inderal, two Flexeril, nine Glynase Prestab, 26 Adderall, 11 Elavil and an assortment of undetermined pills, including 10 small white tablets, Cambridge Chronicle,

Sweet Mother Lortab  -  Jul 23, 2008
But no: Flexeril for the spasms, and good old Lortab for pain as needed, and when isn’t it? They also gave me a “c-collar,� one of those foam neck braces New West,

Cops say meth, narcotics found in drug stop  -  Jul 16, 2008
The officer also allegedly found a bag containing 110 Stacker 3 pills, five Lortab pills, 45 Darvocet pills, 55 Seroquel pills, 63 Flexeril pills and 49 Mannford Eagle,

Courthouse records  -  Jul 9, 2008
...possession of Flexeril, driving under the influence of alcohol or .08 percent (second offense), driving negligently, failing to wear a seat belt, Worcester Telegram,

Mom: System, Doctors Facilitated Son's Prescription Drug Death  -  Aug 1, 2008
By ELAINE SILVESTRINI | The Tampa Tribune A pickup hit her side of the car as she was pulling into the street from a parking lot. A mishap, she said. Tampa Tribune,

Bust results in arrest of three brothers  -  Jun 19, 2008
Javaris Dawsey was charged with possession of MDMA (Ecstasy), possession of a controlled substance (Flexeril, the generic form of Cycolbenzaprine, The Northwest Florida Daily News,

Police: Ringleader of prescription drug forgery group apprehended  -  Jun 28, 2008
Most of the prescriptions were for the painkiller Lortab and the muscle relaxants Flexeril and Soma, according to a Prichard police news release. Press-Register - al.com,

People With Dementia Should Avoid Certain Drugs  -  Jun 27, 2008
Muscle relaxants such as Carisoprodol (Soma), Chlorzoxazone (Parafon Forte), Cyclobenzaprine (Flexeril), Metaxalone (Skelaxin), Methocarbamol (Robaxin) and RedOrbit,

Analysts see higher drug sales for Cephalon  -  Jun 20, 2008
The majority of doctors polled said once-daily Amrix would ultimately replace 5 percent of prescriptions for McNeil-PPC Inc.'s Flexeril and generic versions CNNMoney.com

Deputies intercept mailed drugs  -  Jun 9, 2008
...pack that contained a baggie of 25 yellow pills which turned out to be Vicodin and 27 orange pills which turned out to be Flexeril, Edwards said. Wilmington News Journal, OH,

Medical Marijuana Doctor Gives Straight Answers to Salem-News.com ...  -  Jun 4, 2008
She was first put on flexeril, then oxycontin, and more. She really HATED IT. She now takes 10 mg of Norco and Methadone every 6 hrs on regular days. Salem-News.Com,

NC Central Gives Duke Lacrosse Accuser a Degree and Duke Fans ...  -  May 21, 2008
In fact, Mangum had overdosed on flexeril and booze when she was first picked up by police the night of March 14. Mangum is probably not the first, AOL SPORTS,

Amneal Pharmaceuticals Receives US FDA Approval for Three Generic ...  -  May 7, 2008
Cyclobenzaprine HCl Tablets USP, in 10mg strength, is an AB-Rated therapeutically equivalent alternative to FLEXERIL(R) (a trademark of McNeil Consumer FOXBusiness

ALSO NOTED: Pfizer gets new cancer team to advance key drugs ...  -  May 16, 2008
Report > Ranbaxy got the FDA nod for its muscle relaxant cyclobenzaprine, a generic form of the Ortho-McNeil drug Flexeril. Report > Sepracor shares were FiercePharma,

City cop accused of selling Rx drugs  -  May 8, 2008
Fratticcioli was allegedly dealing in a narcotic called cyclobenzaprine, which is marketed under the brand name Flexeril and Fexmid. The Times of Trenton - NJ.com,

Back Pain: What Works  -  Apr 2, 2008
The drugs with the best data behind them for back pain include anti-inflammatories like ibuprofen and naproxen and muscle relaxants like Flexeril to treat Forbes,

Bloomington man facing drug charges  -  Apr 13, 2008
...two Xanax pills, three and a half Flexeril pills, two Soma pills, one prescription-strength ibuprofen and seven pills police were unable to identify. The Herald-Times (subscription),

Eight Charged With TennCare Fraud  -  Apr 10, 2008
Moore sold a quantity of Flexeril, a prescription muscle relaxer, to an undercover agent of the Wilson County Sheriff's Office. Mary Jean Mitchell, 29, WTVC,

Microcalcifications in breast don't always indicate cancer  -  Mar 27, 2008
Flexeril is an example. Something that has been going on for 15 years without change is unlikely to constitute a serious health threat. DEAR DR. SouthCoastToday.com,

Authorities confiscate meth, pipe bombs in Castle Rock arrest  -  Apr 18, 2008
...of an explosive device without a license, possession of methamphetamine, use of drug paraphernalia and possession of Flexeril without a prescription. Longview Daily News,

Back Pain - Medication for Back Pain  -  Feb 27, 2008
Muscle relaxes are sold under the trade names of Flexeril, Soma, Valium, and others. These medications help to relieve muscle spasm, but may also make American Chronicle,

Doctors learning more about painful condition  -  Feb 13, 2008
...low-dose hydroxyzone or gabapentin to reduce nerve impulses from the vulva to the brain, mood elevators in low doses and the muscle relaxant Flexeril. Chicago Tribune,

2 arrested as deputies find stash of pills, bills  -  Feb 21, 2008
...a bag containing a large quantity of prescription drugs, including 100 oxycodone pills, plus a quantity of clonazepam, Flexeril, Xanax and Valium pills. St. Petersburg Times,

Cyclobenzaprine Extended-Release Tablets Superior to Placebo in ...  -  Feb 18, 2008
...(Flexeril) in alleviating acute muscle spasm," said Arnold Weil, MD, Head, Non-Surgical Orthopaedic & Spine Center, Marietta, Georgia, United States. DG News

Convicted child molester arrested on drug charge  -  Jan 28, 2008
Rowans was arrested on a drug charge after police found a yellow prescription pill, later identified as FLEXERIL, inside the vehicle, according to the Henderson Gleaner,

Woman hits cruiser, faces multiple charges  -  Jan 25, 2008
Deputies also found 55 Valium pills and 52 pills of the muscle relaxer Flexeril, Carter said. Canfield, 54, of Tampa, was charged with DUI with property St. Petersburg Times,

Woman arrested for sideswiping police car  -  Jan 25, 2008
Deputies found 55 Valium pills in a container labeled with a different name and 52 pills of the muscle relaxer Flexeril, police said. United Press International

Driver arrested after sideswiping deputy's cruiser  -  Jan 25, 2008
...deputies say Canfield failed to perform DUI exercises. They also found her in possession of Valium and Flexeril, for which she did not have a prescription. ABC Action News,

Teacher 'Owns Up' To DUI  -  Jan 24, 2008
Origon reported the discovery of 12 white pills, identified as the painkiller Roxicet, and three muscle relaxants called Flexeril. Tampa Tribune,

New Insights Into Genital Pain in Women  -  Jan 30, 2008
...low-dose hydroxyzone or gabapentin to reduce nerve impulses from the vulva to the brain, mood elevators in low doses and the muscle relaxant Flexeril. New York Times,

Courthouse records  -  Jan 22, 2008
...of Seroquel and larceny from a person, sentenced to two concurrent terms of 90 days in the House of Correction; and possession of Flexeril, dismissed. Worcester Telegram,

Car stop leads to drug arrests  -  Jan 16, 2008
...prescription pills without a prescription: Xanax, Levaquin, Tegretol, Zoloft and Flexeril as well as allowing an improper person to operate a vehicle. Hanover Mariner,

Health Matters: What is fibromyalgia?  -  Jan 14, 2008
A muscle relaxant such as Flexeril (cyclobenzaprine) may be used. Depression is also associated with fibromyalgia. If needed, a doctor may prescribe Anderson Independent Mail (subscription),

Witness describes doctor as ‘candy man’  -  Jan 11, 2008
On the first visit, after simply touching her toes and having her legs moved by Tiwari, the female operative was given prescriptions for Flexeril and Ultram The Herald-Times (subscription),

Thieves Hit Several Vonore Businesses  -  Oct 31, 2007
An undetermined amount of Lortab and Flexeril tablets were missing. More is believed to be missing but police are not sure what kind of prescription Monroe County Advocate Democrat,

Teacher accused of DUI  -  Nov 13, 2007
A deputy said he also found three muscle relaxant pills called Flexeril in Mockler’s car. Both drugs require a prescription. Authorities classify drugs on a Hernando Today,

Courthouse records  -  Oct 13, 2007
Michael R. McIntyre Jr., 28, of 90 Main St., Blackstone, charged with possession of Seroquel, larceny from a person, and possession of Flexeril, Worcester Telegram,

Burglars makes off with $1000 worth of prescription drugs  -  Sep 21, 2007
Veterinarian: Hydrocon, Floratab, Flexeril... that's a muscle relaxer. Marie Mortera: What could someone do with those things? KVBC,

Giving Facts On Drugs The Brainwashed Health-Care Delivery System ...  -  Oct 5, 2007
The muscle relaxants are Soma, Flexeril, Robaxin and Skelaxin. The drawbacks are limited effectiveness at tolerated doses, sedation and the anticholinergic Evening Bulletin,

BERICHT: Buy Drugs Without Prescription. No Prior Prescription ...  -  Oct 7, 2007
...soma lounge, soma online, soma pharmacy, prescription drug soma, soma online pharmacy, photo soma pill mp 58, buy cheap soma online, flexeril vs soma, Ermelo.org,

Buy Drugs Without Prescription. Safe and Secure Ordering.  -  Oct 3, 2007
...buy carisoprodol diazepam online soma, soma holiday, buy generic soma, soma versus flexeril, soma medical, soma medicine, soma without prescription, LIVE-Wintersport.com,

Chronic Headaches and Pain Alleviated by Dentistry  -  Sep 15, 2007
Muscle relaxant drugs such as Carisoprodol (Soma) and Cyclobenzaprine (Flexeril). 4. Tricyclic anti-depressant medications such as Amitriptyline (Elavil), 24-7PressRelease.com (press release)

Cephalon, Inc. Announces Agreement to Acquire AMRIX, A Once-Daily ...  -  Aug 23, 2007
AMRIX is a once-a-day, extended-release version of cyclobenzaprine hydrochloride, the active ingredient in the brand Flexeril(R)*. CNNMoney.com

Women's group discusses fibromylagia  -  Aug 22, 2007
Some medications that researches say are affective in the treatment are amitriptyline, Flexeril, or antidepressants such as Prozac. El Defensor Chieftain,

Brand Names/Synonyms:
Flexeril is also known by the following brand names and/or synonymsCyclobenz; Cyclobenzaprine; Cyclobenzaprine Hcl; Flexeril; Flexiban; MK-130; Proeptatriene; Proheptatriene; RP-9715

Drug Category:
Flexeril is categorized under the following by the FDA: Tranquilizing Agents; Muscle Relaxants; Antidepressants; Skeletal Muscle Relaxants; ATC:M03BX08

Dosage Forms:
D-shaped, film coated tablets

Absorption:
Well absorbed after oral administration

Interactions:
-->Interactions for Cyclobenzaprine:

FLEXERIL may have life-threatening interactions with MAO inhibitors.

FLEXERIL may enhance the effects of alcohol, barbiturates, and other CNS depressants.

Tricyclic antidepressants may block the antihypertensive action of guanethidine and similarly acting compounds.

Tricyclic antidepressants may enhance the seizure risk in patients taking tramadol.

 




Chemical IUPAC Name:
3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine

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