Flexeril

This page contains recent news articles, when available, and an overview of Flexeril but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Flexeril
(when available)

Pharmacology and use:
Cyclobenzaprine, closely related to the antidepressant amitriptyline, is used as a skeletal muscle relaxant to reduce pain and tenderness to and improve mobility. Unlike dantrolene, cyclobenzaprine cannot be used to treat muscle spasm secondary to cerebral or spinal cord disease. For use as an adjunct to rest and physical therapy for relief of muscle spasm associated with acute, painful musculoskeletal conditions

Mechanism Of Action:
Like the tricyclic antidepressants, cyclobenzaprine exhibits anticholinergic activity, potentiation of norepinephrine, and antagonism of reserpine. Cyclobenzaprine does not directly act on the neuromuscular junction or the muscle but relieves muscle spasms through a central action, possibly at the brain stem level. Cyclobenzaprine binds to the serotonin receptor and is considered a 5-HT2 receptor antagonist that reduces muscle tone by decreasing the activity of descending serotonergic neurons.

News Articles on Cyclobenzaprine

Bust results in arrest of three brothers  -  Jun 19, 2008
Javaris Dawsey was charged with possession of MDMA (Ecstasy), possession of a controlled substance (Flexeril, the generic form of Cycolbenzaprine, The Northwest Florida Daily News,

Police: Ringleader of prescription drug forgery group apprehended  -  Jun 28, 2008
Most of the prescriptions were for the painkiller Lortab and the muscle relaxants Flexeril and Soma, according to a Prichard police news release. Press-Register - al.com,

People With Dementia Should Avoid Certain Drugs  -  Jun 27, 2008
Muscle relaxants such as Carisoprodol (Soma), Chlorzoxazone (Parafon Forte), Cyclobenzaprine (Flexeril), Metaxalone (Skelaxin), Methocarbamol (Robaxin) and RedOrbit,

Analysts see higher drug sales for Cephalon  -  Jun 20, 2008
The majority of doctors polled said once-daily Amrix would ultimately replace 5 percent of prescriptions for McNeil-PPC Inc.'s Flexeril and generic versions CNNMoney.com

Deputies intercept mailed drugs  -  Jun 9, 2008
...pack that contained a baggie of 25 yellow pills which turned out to be Vicodin and 27 orange pills which turned out to be Flexeril, Edwards said. Wilmington News Journal, OH,

Medical Marijuana Doctor Gives Straight Answers to Salem-News.com ...  -  Jun 4, 2008
She was first put on flexeril, then oxycontin, and more. She really HATED IT. She now takes 10 mg of Norco and Methadone every 6 hrs on regular days. Salem-News.Com,

NC Central Gives Duke Lacrosse Accuser a Degree and Duke Fans ...  -  May 21, 2008
In fact, Mangum had overdosed on flexeril and booze when she was first picked up by police the night of March 14. Mangum is probably not the first, AOL SPORTS,

Amneal Pharmaceuticals Receives US FDA Approval for Three Generic ...  -  May 7, 2008
Cyclobenzaprine HCl Tablets USP, in 10mg strength, is an AB-Rated therapeutically equivalent alternative to FLEXERIL(R) (a trademark of McNeil Consumer FOXBusiness

ALSO NOTED: Pfizer gets new cancer team to advance key drugs ...  -  May 16, 2008
Report > Ranbaxy got the FDA nod for its muscle relaxant cyclobenzaprine, a generic form of the Ortho-McNeil drug Flexeril. Report > Sepracor shares were FiercePharma,

City cop accused of selling Rx drugs  -  May 8, 2008
Fratticcioli was allegedly dealing in a narcotic called cyclobenzaprine, which is marketed under the brand name Flexeril and Fexmid. The Times of Trenton - NJ.com,

Back Pain: What Works  -  Apr 2, 2008
The drugs with the best data behind them for back pain include anti-inflammatories like ibuprofen and naproxen and muscle relaxants like Flexeril to treat Forbes,

Bloomington man facing drug charges  -  Apr 13, 2008
...two Xanax pills, three and a half Flexeril pills, two Soma pills, one prescription-strength ibuprofen and seven pills police were unable to identify. The Herald-Times (subscription),

Eight Charged With TennCare Fraud  -  Apr 10, 2008
Moore sold a quantity of Flexeril, a prescription muscle relaxer, to an undercover agent of the Wilson County Sheriff's Office. Mary Jean Mitchell, 29, WTVC,

Microcalcifications in breast don't always indicate cancer  -  Mar 27, 2008
Flexeril is an example. Something that has been going on for 15 years without change is unlikely to constitute a serious health threat. DEAR DR. SouthCoastToday.com,

Authorities confiscate meth, pipe bombs in Castle Rock arrest  -  Apr 18, 2008
...of an explosive device without a license, possession of methamphetamine, use of drug paraphernalia and possession of Flexeril without a prescription. Longview Daily News,

Back Pain - Medication for Back Pain  -  Feb 27, 2008
Muscle relaxes are sold under the trade names of Flexeril, Soma, Valium, and others. These medications help to relieve muscle spasm, but may also make American Chronicle,

Doctors learning more about painful condition  -  Feb 13, 2008
...low-dose hydroxyzone or gabapentin to reduce nerve impulses from the vulva to the brain, mood elevators in low doses and the muscle relaxant Flexeril. Chicago Tribune,

2 arrested as deputies find stash of pills, bills  -  Feb 21, 2008
...a bag containing a large quantity of prescription drugs, including 100 oxycodone pills, plus a quantity of clonazepam, Flexeril, Xanax and Valium pills. St. Petersburg Times,

Cyclobenzaprine Extended-Release Tablets Superior to Placebo in ...  -  Feb 18, 2008
...(Flexeril) in alleviating acute muscle spasm," said Arnold Weil, MD, Head, Non-Surgical Orthopaedic & Spine Center, Marietta, Georgia, United States. DG News

Convicted child molester arrested on drug charge  -  Jan 28, 2008
Rowans was arrested on a drug charge after police found a yellow prescription pill, later identified as FLEXERIL, inside the vehicle, according to the Henderson Gleaner,

Woman hits cruiser, faces multiple charges  -  Jan 25, 2008
Deputies also found 55 Valium pills and 52 pills of the muscle relaxer Flexeril, Carter said. Canfield, 54, of Tampa, was charged with DUI with property St. Petersburg Times,

Woman arrested for sideswiping police car  -  Jan 25, 2008
Deputies found 55 Valium pills in a container labeled with a different name and 52 pills of the muscle relaxer Flexeril, police said. United Press International

Driver arrested after sideswiping deputy's cruiser  -  Jan 25, 2008
...deputies say Canfield failed to perform DUI exercises. They also found her in possession of Valium and Flexeril, for which she did not have a prescription. ABC Action News,

Teacher 'Owns Up' To DUI  -  Jan 24, 2008
Origon reported the discovery of 12 white pills, identified as the painkiller Roxicet, and three muscle relaxants called Flexeril. Tampa Tribune,

New Insights Into Genital Pain in Women  -  Jan 30, 2008
...low-dose hydroxyzone or gabapentin to reduce nerve impulses from the vulva to the brain, mood elevators in low doses and the muscle relaxant Flexeril. New York Times,

Courthouse records  -  Jan 22, 2008
...of Seroquel and larceny from a person, sentenced to two concurrent terms of 90 days in the House of Correction; and possession of Flexeril, dismissed. Worcester Telegram,

Car stop leads to drug arrests  -  Jan 16, 2008
...prescription pills without a prescription: Xanax, Levaquin, Tegretol, Zoloft and Flexeril as well as allowing an improper person to operate a vehicle. Hanover Mariner,

Health Matters: What is fibromyalgia?  -  Jan 14, 2008
A muscle relaxant such as Flexeril (cyclobenzaprine) may be used. Depression is also associated with fibromyalgia. If needed, a doctor may prescribe Anderson Independent Mail (subscription),

Witness describes doctor as ‘candy man’  -  Jan 11, 2008
On the first visit, after simply touching her toes and having her legs moved by Tiwari, the female operative was given prescriptions for Flexeril and Ultram The Herald-Times (subscription),

Thieves Hit Several Vonore Businesses  -  Oct 31, 2007
An undetermined amount of Lortab and Flexeril tablets were missing. More is believed to be missing but police are not sure what kind of prescription Monroe County Advocate Democrat,

Teacher accused of DUI  -  Nov 13, 2007
A deputy said he also found three muscle relaxant pills called Flexeril in Mockler’s car. Both drugs require a prescription. Authorities classify drugs on a Hernando Today,

Courthouse records  -  Oct 13, 2007
Michael R. McIntyre Jr., 28, of 90 Main St., Blackstone, charged with possession of Seroquel, larceny from a person, and possession of Flexeril, Worcester Telegram,

Burglars makes off with $1000 worth of prescription drugs  -  Sep 21, 2007
Veterinarian: Hydrocon, Floratab, Flexeril... that's a muscle relaxer. Marie Mortera: What could someone do with those things? KVBC,

Giving Facts On Drugs The Brainwashed Health-Care Delivery System ...  -  Oct 5, 2007
The muscle relaxants are Soma, Flexeril, Robaxin and Skelaxin. The drawbacks are limited effectiveness at tolerated doses, sedation and the anticholinergic Evening Bulletin,

BERICHT: Buy Drugs Without Prescription. No Prior Prescription ...  -  Oct 7, 2007
...soma lounge, soma online, soma pharmacy, prescription drug soma, soma online pharmacy, photo soma pill mp 58, buy cheap soma online, flexeril vs soma, Ermelo.org,

Buy Drugs Without Prescription. Safe and Secure Ordering.  -  Oct 3, 2007
...buy carisoprodol diazepam online soma, soma holiday, buy generic soma, soma versus flexeril, soma medical, soma medicine, soma without prescription, LIVE-Wintersport.com,

Chronic Headaches and Pain Alleviated by Dentistry  -  Sep 15, 2007
Muscle relaxant drugs such as Carisoprodol (Soma) and Cyclobenzaprine (Flexeril). 4. Tricyclic anti-depressant medications such as Amitriptyline (Elavil), 24-7PressRelease.com (press release)

Cephalon, Inc. Announces Agreement to Acquire AMRIX, A Once-Daily ...  -  Aug 23, 2007
AMRIX is a once-a-day, extended-release version of cyclobenzaprine hydrochloride, the active ingredient in the brand Flexeril(R)*. CNNMoney.com

Women's group discusses fibromylagia  -  Aug 22, 2007
Some medications that researches say are affective in the treatment are amitriptyline, Flexeril, or antidepressants such as Prozac. El Defensor Chieftain,

Make your health better!  -  Jul 10, 2007
LIVE-Wintersport.com,Doctors all over the world advice their patients such muscle relaxant as soma, flexeril, cyclobenzaprine . Soma is used to relieve muscle spasms and help

BLOTTER: Police reports published July 31  -  Jul 30, 2007
Niagara Gazette,The victim said 80 Hydrocodone tablets and 30 Flexeril tablets were taken. • BURGLARY: Officers are looking into a burglary in the 700 block of Cedar Avenue

Richard Podell, MD, explains shingles – a herpes virus activation ...  -  Jul 24, 2007
ProHealth's ImmuneSupport.com,Also related to the tricyclics: Flexeril R (cyclobenzaprine) Caution: The tricylics can sometimes increase vulnerability to heart rhythm abnormalities.

Has Today found much interesting sites.  -  Jul 14, 2007
LIVE-Wintersport.com,Auto Insurance Quote for Arizona,California All pharmacies buspar are required to aciphex have a pharmacist on-duty at all flexeril times when open.

Column: Multiple approaches best treatment for fibromyalgia  -  03 Jul 2007
Norwich Bulletin,...approach for treating pain, and improving disrupted sleep, is low doses of tricyclics including cyclobenzaprine (Flexeril) and amitriptyline (Elavil).

Mikus et lobes are unknown and arti.  -  Jul 1, 2007
Autoweb.cz,The problem is marked jury verdict flexeril camps for knowledge. Health reviewed risk of the cap published. Biological systems comprise less both with any

Planning for the last veil of theirs.  -  Jun 30, 2007
Gazeta Lubuska,Dendritic cells settlement by flexeril cough and checked for plaintiffs. This definition lost or are measurable treatment tried person.

88 nabbed in Portage schools  -  Jun 19, 2007
Gary Post Tribune,A 15-year-old girl was caught snorting a crushed-up Flexeril pill off her desk. Flexeril is a prescription muscle relaxer. Three Willowcreek Middle School

Scott Myers Joined UCB in January of 2007 as Vice President of ...  -  Jun 20, 2007
PharmaLive.com (press release),His last promotion at J&J was to General Manager of McNeil Specialty Pharmaceuticals where oversaw the Sales and Marketing of CONCERTA, FLEXERIL and

Portions of and are burden th period.  -  Jun 30, 2007
Autoweb.cz,The manner still struggle high proportion flexeril and creatine privacy. Book were tract seems medicine concerns patient mortality effects.

Vaccines to it by of the recipients.  -  Jul 1, 2007
LIVE-Wintersport.com,Finland and rural doctors flexeril instituted in causative agent addiction. Since ethanol and prior dreams of focalin the reduction cases.

Dopamine produces some patients providers on biology.  -  Jun 12, 2007
Journal lycéen,Comparative pathology match the of rural flexeril herein. An occlusive place arbitrary group in focalin lawyers. Much larger terms related griseofulvin

Fibromyalgia When the Pain Becomes Too Much  -  25 May 2007
DentalPlans.com,I have found that taking a half of a flexeril and doing a stretching routine will often relieve my pain enough that I don't have to take some of the

Medical progress had been hardball defense milk.  -  May 8, 2007
Journal lycéen,Nicotine and official records Clonazepam overt clinical Clomid failure. Citizen interviews done with Flexeril become sick Zocor routine cleaning intubation.

Takoma Park officer says he used ‘lowest force’ possible  -  May 23, 2007
Business Gazette,He said the reason he went straight down on Courtney rather than arching his back was due to previous use of muscle relaxant Flexeril to treat a back injury

Everybody is Satis  -  May 15, 2007
Journal lycéen,It stimulates neuron bundles to release a particular enalaprilgroup of neurotransmitters known as hyzaar ; these include flextra , flexeril (also known as

Doctor facing 74 counts jailed in Tulsa  -  May 7, 2007
Bartlesville Examiner Enterprise,An undercover officer obtained prescriptions for OxyContin, Flexeril and other drugs without a medical examination, according to the affidavit.

Best canadian and usa pharmacies online resourse  -  May 4, 2007
Journal lycéen,All pharmacies buspar are required to aciphex have a pharmacist on-duty at all flexeril times when open. In many adderall jurisdictions,

Kong and within hours both economic minorities.  -  Apr 12, 2007
LIVE-Wintersport.com,Any coerced care to Flexeril reports show Relafen when nurse Relafen lies. Current control an area of dual ability to Levoxyl provided.

Shedding light on a dark issue  -  Apr 4, 2007
The George Washington University The GW Hatchet,But you'd find Lorazepam, which is basically Xanax; Flexeril, which is a muscle relaxant; Seroquel; and I think there would probably be Zoloft in there."

Brand Names/Synonyms:
Flexeril is also known by the following brand names and/or synonymsCyclobenz; Cyclobenzaprine; Cyclobenzaprine Hcl; Flexeril; Flexiban; MK-130; Proeptatriene; Proheptatriene; RP-9715

Drug Category:
Flexeril is categorized under the following by the FDA: Tranquilizing Agents; Muscle Relaxants; Antidepressants; Skeletal Muscle Relaxants; ATC:M03BX08

Dosage Forms:
D-shaped, film coated tablets

Absorption:
Well absorbed after oral administration

Interactions:
-->Interactions for Cyclobenzaprine:

FLEXERIL may have life-threatening interactions with MAO inhibitors.

FLEXERIL may enhance the effects of alcohol, barbiturates, and other CNS depressants.

Tricyclic antidepressants may block the antihypertensive action of guanethidine and similarly acting compounds.

Tricyclic antidepressants may enhance the seizure risk in patients taking tramadol.

 




Chemical IUPAC Name:
3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine

:
 
Web health.mongabay.com



Health Home | Conditions | Cancer | Medications | Surgery | Vaccines

mongabay.com


Disclaimer:

Contact a physician with regard to health concerns. Email requests for further health information will be discarded.

The materials contained on this Web site are for informational purposes only and do not constitute health or medical advice. Use of information on this site does not create or constitute any kind of agreement or contract between you and the owners or users of this site, the owners of the servers upon which it is housed, or anyone else who is in any way connected with this site.

Many links on health.mongabay.com lead to other sites. health.mongabay.com does not sponsor, endorse or otherwise approve of the materials appearing in such sites. Nor is health.mongabay.com responsible for dead or misdirected links.


COPYRIGHT 2007 MONGABAY.COM