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FamvirThis page contains recent news articles, when available, and an overview of Famvir but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.Overview: Famvir (when available) Famciclovir is a prodrug that undergoes rapid biotransformation to the active antiviral compound penciclovir. Penciclovir is an anti-viral drug which has inhibitory activity against herpes simplex virus types 1 (HSV-1) and 2 (HSV-2) and varicella zoster virus (VZV). Therefore, herpes viral DNA synthesis and replication are selectively inhibited. For the treatment of acute herpes zoster (shingles); For the treatment or suppression of recurrent genital herpes in immunocompetent patients and treatment of recurrent mucocutaneous herpes simplex infections in HIV infected patients. Mechanism Of Action: Famciclovir undergoes rapid biotransformation to the active antiviral compound penciclovir, which has inhibitory activity against herpes simplex virus types 1 (HSV-1) and 2 (HSV-2) and varicella zoster virus (VZV). In cells infected with HSV-1, HSV-2 or VZV, viral thymidine kinase phosphorylates penciclovir to a monophosphate form that, in turn, is converted to penciclovir triphosphate by cellular kinases. In vitro studies demonstrate that penciclovir triphosphate inhibits HSV-2 DNA polymerase competitively with deoxyguanosine triphosphate. Consequently, herpes viral DNA synthesis and, therefore, replication are selectively inhibited. News Articles on Famciclovir Betsy Wadland: Avoiding shingles as an adult - 02 Jun 2008 Similar drugs, such as Valtrex or Famvir, can also be used. These drugs may also help stave off the painful aftereffects of shingles known as postherpetic Norwich Bulletin, Teva Announces Launch Of Generic Wellbutrin XL(R) Tablets, 150 Mg - 02 Jun 2008 Neurontin®, Lotrel®, Famvir® and Protonix®, Teva's ability to successfully develop and commercialize additional pharmaceutical products, Medical News Today (press release), Shingles: Treatment and prevention - May 23, 2008 Such medications include acyclovir (Zovirax), valacyclovir (Valtrex) or famciclovir (Famvir). The medicines work best when given within the first 72 hours Scotts Valley/San Lorenzo Valley Press-Banner, It's Official: Get Your Shingles Vaccination - May 16, 2008 The prescription antiviral medications acyclovir (Zovirax), valacyclovir (Valtrex), and famciclovir (Famvir), are used to treat shingles, but they should be U.S. News & World Report, Sector Snap: Goldman looking for Teva patent suit updates - May 5, 2008 ...patent on oral contraceptive Yasmin, and the trial for Novartis' Famvir herpes drug _ which Teva launched an at-risk generic version of in September. CNNMoney.com Vaccine for shingles suggested for anyone over 60 - May 15, 2008 Anti-viral medication, including Zovirax, Valtrex and Famvir, should be taken within 72 hours of onset to reduce symptoms, Ms. Williams said. Pittsburgh Post Gazette, * Novartis on track in 2008: - Apr 20, 2008 These products - Zelnorm, Lotrel, Trileptal, Lamisil and Famvir - had combined total net sales in the US of USD 3.1 billion in 2006, and net sales for this Market Wire (press release) Problems with low cholesterol pop up - Apr 20, 2008 Your doctor could prescribe acyclovir (Zovirax), famciclovir (Famvir) or valacyclovir (Valtrex). You should not worry about the pharmacy where you purchase Houston Chronicle, Early Treatment with COPAXONE(R) Significantly Delayed Progression ... - Apr 17, 2008 Neurontin(R), Lotrel(R), Famvir(R) and Protonix(R), Teva's ability to successfully develop and commercialize additional pharmaceutical products, FOXBusiness Novartis reports higher sales and - Apr 20, 2008 These products - Zelnorm, Lotrel, Trileptal,Lamisil and Famvir - had combined total net sales in the US of USD3.1 billion in 2006, and net sales for this Ad-Hoc-News (Pressemitteilung), A New Fibromyalgia Remedy: Antiviral Drugs - Apr 11, 2008 Control the viruses using the antiviral drugs famciclovir (brand name Famvir) or valacyclovir (Valtrex). What we find in these people who have active U.S. News & World Report, Novartis Q1 earnings beat forecasts, confirms outlook UPDATE - Apr 20, 2008 These products, Zelnorm, Lotrel, Trileptal, Lamisil and Famvir, had combined sales of $1.7 billion in 2007. The year-on-year impact of lost sales will only CNNMoney.com Teva Provides Update on Generic Aricept(R) Litigation - Mar 28, 2008 Neurontin®, Lotrel®, Famvir® and Protonix®, Teva's ability to successfully develop and commercialize additional pharmaceutical products, WELT ONLINE, COPAXONE(R) Significantly Reduced Brain Atrophy and Tissue Loss ... - Apr 17, 2008 Neurontin ® , Lotrel ® , Famvir ® and Protonix ® , Teva's ability to successfully develop and commercialize additional pharmaceutical products, Earthtimes, She contracted genital herpes - Mar 5, 2008 The relatively expensive drugs acyclovir (Zovirax), famciclovir (Famvir), and valacyclovir (Valtrex) are used. These drugs are effective in reducing the Jamaica Gleaner, Treating Herpes Naturally and with Fewer Side Effects - Mar 4, 2008 ...antiviral medications for controlling herpes outbreaks, including aciclovir (Zovirax), valaciclovir (Valtrex), famciclovir (Famvir), and penciclovir. Natural News.com, Home blood sugar machines not precision instruments - Feb 27, 2008 Acyclovir, valacyclovir (Valtrex) and famciclovir (Famvir) tablets can do the same. If a person has six or more outbreaks in a year, then that person can Orillia Packet & Times, Nomura Downgrades European Pharma, Citing Generics, FDA - Mar 6, 2008 ...reflux drug Nexium, while Novartis has already seen its top line eaten away by generic versions of Famvir, for shingles, and antifungal Lamisil, they said. CNNMoney.com Teva's Developed G-CSF is the First Biosimilar to Receive a ... - Feb 21, 2008 Neurontin(R), Lotrel(R) Famvir(R), and Protonix(R), Teva's ability to successfully develop and commercialize additional pharmaceutical products, FOXBusiness UPDATE: Teva Pharma 4Q Net Up 24%, Plans R&D Increase - Feb 12, 2008 ...as well as sales of other generic products such as Oxycodone, and Novartis AG's (NVS) blood-pressure medicine Lotrel and antiviral Famvir. CNNMoney.com Teva Reports Fourth Quarter and Full Year 2007 Results - Feb 11, 2008 Neurontin®, Lotrel® Famvir®, and Protonix®, Teva's ability to successfully develop and commercialize additional pharmaceutical products, WELT ONLINE, Novartis to cut 2500 jobs worldwide by 2010, offers downbeat ... - Feb 15, 2008 Growth in the US will be hurt by the loss of sales from bowel drug Zelnorm and generic competition for the company's Lamisil, Lotrel, Famvir and Trileptal AOL Canada, Novartis' ex-chief does U-turn back to J&J - Feb 14, 2008 ...sales of the high blood pressure drug Lotrel, the fungal infection treatment Lamisil, epilepsy drug Trileptal and the viral infection medication Famvir. The Star-Ledger - NJ.com, Teva Announces Approval of Generic Fosamax(R) Tablets, 5 mg, 10 mg ... - 06 Feb 2008 Neurontin(R), Lotrel(R) Famvir(R) and Protonix(R), Teva's ability to successfully develop and commercialize additional pharmaceutical products, FOXBusiness Dividends, Buybacks Mask Novartis' Symptoms - Jan 20, 2008 Sales of its hypertension drug Lotrel, anti-fungal Lamasil and anti-viral Famvir all have been undermined by the aggressive entrance in the market of Barron's Novartis Profit Falls as Drugs Lose Sales to Generics (Update8) - Jan 17, 2008 ...``We had two where we expected generic competition, Lamisil and Trileptal, and two where we still have patents and got competition, Lotrel and Famvir. Bloomberg Health Tip: Understanding Shingles - Jan 24, 2008 Your doctor may opt for a prescription medication including acyclovir (brand name: Zovirax), famciclovir (Famvir) or valacyclovir (Valtrex). Washington Post, Novartis profit drops 45%; plans hefty buyback - Jan 17, 2008 ...after generic competition for blood-pressure medication Lotrel, the Lamisil nail-fungus treatment, epilepsy drug Trileptal and herpes drug Famvir. MarketWatch Novartis profits jump 66 per cent in 2007 - Jan 17, 2008 Sales in the United States were down eight percent after the suspension of Zelnorm and the loss of patents on Lotrel, Lamisil, Trileptal and Famvir. Economic Times, D Ravi Kanth: Drug capitalism - Feb 4, 2008 Teva decided to produce generic versions of the blockbuster blood-pressure drug Lotrel and herpes-drug Famvir — two major branded drugs of Novartis — in the Business Standard, Novartis Q4 profit plummets on restructuring hit - Jan 17, 2008 ...(almodipine/benazepril), Lamisil (terbinafine), Trileptal (oxcarbazepine) and Famvir (famciclovir) enabling copycat drugs to eat into market shares. Pharma Times (subscription), Shingles - A strange name for a strange disease - Jan 15, 2008 Usually antiviral medicines (such as Famvir, Zovirax, Valtrex) are used to limit the spread of shingles, speed healing, and reduce the pain. Gather.com, BROKERWATCH AstraZeneca downgraded to 'neutral' from 'overweight ... - Feb 1, 2008 The broker noted that Teva was the first to file and recently launched three at-risk drugs (Lotrel, Famvir and Protonix), and it feels Seroquel could be Euro2day, Novartis: Latest Victim Of US Economy - Jan 17, 2008 ...a hypertension treatment, Lamasil, an anti-fungus treatment, and Famvir, an anti-virus medication, sales growth will be limited in the near-term. Forbes, Charges Knock Novartis Results - Jan 17, 2008 Trileptal, Lamisil and Famvir -- in the US during 2007. Those products accounted for $3.1 billion in sales in 2006, but only $1.7 billion in 2007. TheStreet.com Retailers, banks pace European share gains - Jan 17, 2008 US pharmaceutical sales fell 21% in the quarter due to generic competition for four products - Lotrel, Lamisil, Trileptal and Famvir - and the suspension of MarketWatch Novartis Q4 hit by restructuring, weak US pharma sales; new share ... - Jan 17, 2008 ...due to generic competition for four products -- Lotrel, Lamisil, Trileptal and Famvir -- and the suspension of irritable bowel syndrome drug Zelnorm. CNNMoney.com Teva, generic firms seen doing more risky launches - Jan 16, 2008 Israel-based Teva took a similar calculated risk last year with its generics of the big-selling blood-pressure drug Lotrel and the herpes treatment Famvir, Guardian Unlimited, Novartis achieves record results in 2007 underscoring benefits of ... - Jan 16, 2008 US net sales fell 8% after the loss of Lotrel, Lamisil, Trileptal and Famvir to generics and the suspension of Zelnorm. However, worldwide net sales rose Market Wire (press release) Novartis achieves record results in - Jan 16, 2008 Cost of Goods Sold was higher due mainly to a USD 320million intangible asset impairment charge for Famvir product rights.Vaccines and DiagnosticsThe strong Ad-Hoc-News (Pressemitteilung), Teva to Acquire CoGenesys - Jan 22, 2008 Neurontin(R), Lotrel(R) Famvir(R) and Protonix(R), Teva`s ability to successfully develop and commercialize additional pharmaceutical products, PharmaLive.com (press release), Alternative Medicines And Treatment For Shingles - Nov 12, 2007 Shingles is often treated with acyclovir (brand name: Zovirax), famciclovir (brand name: Famvir) or valacyclovir (brand name: Valtrex). American Chronicle, High blood pressure may not have a specific cause - Nov 2, 2007 It is worth noting here that the antiviral medication Famvir -- previously only available for people with shingles or genital herpes -- is now available on The Australian, Ask Dr. H | Dealing with the pain of shingles - Nov 5, 2007 Antiviral medications such as Valtrex or Famvir, if started within the first 72 hours of an outbreak, can halve the duration of post-herpetic nerve pain. Philadelphia Inquirer, Novartis to cut more than 1000 jobs in US - Oct 19, 2007 Novartis also had to forgo sales of its bowel drug Zelnorm, after it was withdrawn from the US market, and sales of three of its medicines - Famvir, People's Daily Online, Novartis Delivers Record Earnings in First Nine Months of 2007 ... - Oct 18, 2007 US net sales fell 3% as growth from many brands were offset by the Zelnorm suspension in March as well as generic competition for Lotrel, Lamisil and Famvir PharmaLive.com (press release), Teva Announces Planned Retirement of CFO Dan Suesskind in Mid-2008 - Oct 29, 2007 ...including that relating to the generic versions of Allegra®, Neurontin®, Lotrel®, and Famvir®, the effects of competition on our innovative products, WELT ONLINE, Adenoscan(R) Patent Lawsuits Settled - Oct 22, 2007 Lotrel(R), and Famvir(R), the effects of competition on our innovative products, especially Copaxone(R) sales, the impact of pharmaceutical industry CNNMoney.com Novartis appoints new head of pharma - Oct 18, 2007 Apart from the $5.2bn divestment gains, Novartis took a $320m write-off because of the dangers of generic challenges to Famvir, the antiviral drug for MSNBC Pfizer, Wyeth Net Falls on Costs; Novartis, Lilly Up (Update3) - Oct 18, 2007 ...by the withdrawal of Zelnorm and the start of generic competition to heart medicine Lotrel, genital herpes treatment Famvir and anti-fungal Lamisil. Bloomberg Event Brief of Q3 2007 Teva Pharmaceutical Earnings Conference ... - Nov 6, 2007 Again, you mentioned Lotrel and Famvir and actually Allegra, which has been in our line for some time, has done well as Bupropion, so there are a number of Insurance News Net (press release), Seeing potential across the pond, IPG adds UK agency to Integrated - Oct 25, 2007 Meanwhile, two other ICC accounts, Novartis' Lotrel and Famvir, were exposed to generic competition. This month the Swiss firm announced a plan to lay off Medical Marketing and Media, INHX: Begins Ph I Trial of FV-100 to Treat Herpes Zoster (Shingles) - Oct 24, 2007 ...or prodrugs such as Novartis's (NVS) Famvir(R)(famciclovir), or glaxosmithkline's Valtrex(R) (valacyclovir). Maximum efficacy of antiviral drugs occurs Trading Markets (press release), Merrill Lynch: Teva will beat estimates - Oct 22, 2007 ...for the third quarter could be conservative given the exclusive launch of generic Lotrel in May and the launch of generic Famvir, both launches at risk. Globes, Teva can resume selling Famvir copy - Sep 30, 2007 Famvir, which contains the active ingredient famciclovir, had sales of $200 million for the 12 months ended June 30, Petah Tikva-based Teva said this month, Jerusalem Post, Teva Can Resume Generic Famvir Sales - Oct 8, 2007 The court had issued an order temporarily enjoining Teva from selling generic Famvir (famciclovir) tablets while it considered Novartis’ emergency motion FDA news (subscription), Novartis down as Teva says can sell Famvir generic - Oct 1, 2007 O: Quote, Profile, Research) said it can now resume sales of its generic version of the Swiss company's herpes drug, Famvir. Novartis shares were 0.4 Reuters Court decides that Teva can start selling generic Famvir again - Oct 1, 2007 Teva Pharmaceutical Industries has been granted approval to restart selling its copycat version of Novartis’ Famvir for herpes in the USA and has made a Pharma Times (subscription), Teva to resume sales of generic Famvir - Sep 30, 2007 Teva added that it could resume sales of Famciclovir tablets, its generic version of Novartis' Famvir for the treatment of shingles and genital herpes. Globes, United States: Three Days In September: Generic Famvir ... - Sep 28, 2007 In a temporary reprieve from a district court's order that allowed Teva to launch a generic version of Novartis’s Famvir®, Judge Alvin A. Schall of the US Mondaq News Alerts (subcription), Teva Announces Court of Appeals Denies Novartis Emergency Motion ... - Sep 28, 2007 Teva can resume sales of its generic Famciclovir Tablets, AB-rated to Novartis Famvir Tablets. (NASDAQ: TEVA), headquartered in Israel, is among the top 20 InfoBolsa, Teva Says Appeals Court Denied Novartis' Emergency Motion On ... - Sep 28, 2007 Teva can resume sales of its generic Famciclovir Tablets, AB-rated to Novartis' Famvir Tablets. Earlier this month, Teva said that US court of Appeals for Trading Markets, Appeals Court Stops Teva From Selling Generic Famvir - Sep 17, 2007 24 that it received final approval to market generic Famvir (famciclovir) tablets but said it would not launch the product until after a Sept. FDA news (subscription), What to do, and not do, about shingles - Oct 11, 2007 However, if it did not work, you would have lost precious time in starting a prescription antiviral drug (Famvir, Valtrex, or acyclovir), which is most SunHerald.com, Treatment of diverticulitis, shingles pain ASK DR. H MITCHELL HECHT - Oct 8, 2007 Antiviral medication like Valtrex or Famvir, if started within the first 72 hours of an outbreak, can cut the duration of post-herpetic nerve pain by more Wilkes Barre Times-Leader, OUTLOOK Novartis Q3 net seen lower on weaker sales growth hit by ... - Oct 12, 2007 Analysts'' focus is on sales erosion from generic forms of key drugs, including epilepsy drug Trileptal, herpes drug Famvir, blood pressure treatment Lotrel Euro2day, Teva Announces the Introduction of Famciclovir Tablets - Oct 5, 2007 This product is AB rated and bioequivalent to Famvir®* Tablets. Famciclovir Tablets are available in 125 mg, 250 mg, and 500 mg strengths, in bottle sizes PharmaLive.com (press release), Novartis CEO says 'dont expect Prexige approval - Sep 14, 2007 Setbacks for Novartis have included earlier-than-expected generic competition for the antiviral Famvir and a delay in approval for the diabetes drug Galvus, Medical Marketing and Media, BERICHT: Buy Drugs Without Prescription. No Prior Prescription ... - Oct 7, 2007 ...exelon chicago, exelon patients, exelon and cholinergic, novartis and teva and famvir and bioresearcher and september 7, fda and approvals and famvir Ermelo.org, Buy Drugs Without Prescription. Safe and Secure Ordering. - Oct 3, 2007 ...lawsuit exelon general atomics heathgate uranium, adult dose famvir, novartis and famvir and september 5, tell me what is femara, femara side effects, LIVE-Wintersport.com, Swiss shares close higher as banking sector, UBS reverse losses UPDATE - Oct 1, 2007 Earlier, a US court granted Teva the right to sell a generic of Novartis' herpes drug Famvir. Roche rose 1.60 sfr to close at 212.70. CNNMoney.com Deutsche Wohnen, Infineon, Leclanche: European Equity Preview - Sep 30, 2007 ...generic-drug company, said a US appeals court ruled it can resume selling a lower-cost version of Novartis's Famvir treatment for genital herpes. Bloomberg Teva Provides Update on Generic Neurontin(R) Litigation - Sep 21, 2007 ...including that relating to the generic versions of Allegra®, Neurontin®, Lotrel®, and Famvir®, the effects of competition on our innovative products, Die Welt, Teva Pharmaceutical To Restart Sales Of Famciclovir Tablets ... - Sep 28, 2007 Accordingly, Teva could restart sales of its generic Famciclovir Tablets, AB-rated to Novartis' Famvir Tablets. The company said this development is further Trading Markets, Long-Term Study Shows Copaxone Significantly Slows Progression of ... - Oct 12, 2007 Lotrel(R), and Famvir(R), the effects of competition on our innovative products, especially Copaxone(R) sales, the impact of pharmaceutical industry PharmaLive.com (press release), Brand Names/Synonyms: Famvir is also known by the following brand names and/or synonymsCHEMBANK1696; FCV; Famciclovir; Famciclovir 98.5; Famciclovir [Usan:Ban:Inn]; Famciclovirum [Inn-Latin]; Famvir Drug Category: Famvir is categorized under the following by the FDA: Prodrugs; Antivirals; Nucleosides and Nucleotides (08:18.32); ATC:J05AB09; ATC:S01AD07 Dosage Forms: Tablet Absorption: 77% Interactions: Interactions for Famciclovir: Concurrent use with probenecid or other drugs significantly eliminated by active renal tubular secretion may result in increased plasma concentrations of penciclovir. The conversion of 6-deoxy penciclovir to penciclovir is catalyzed by aldehyde oxidase. Interactions with other drugs metabolized by this enzyme could potentially occur. Chemical IUPAC Name: [2-(acetyloxymethyl)-4-(2-aminopurin-9-yl)-butyl] acetate : |
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