Famvir

This page contains recent news articles, when available, and an overview of Famvir but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Famvir
(when available)

Pharmacology and use:
Famciclovir is a prodrug that undergoes rapid biotransformation to the active antiviral compound penciclovir. Penciclovir is an anti-viral drug which has inhibitory activity against herpes simplex virus types 1 (HSV-1) and 2 (HSV-2) and varicella zoster virus (VZV). Therefore, herpes viral DNA synthesis and replication are selectively inhibited. For the treatment of acute herpes zoster (shingles); For the treatment or suppression of recurrent genital herpes in immunocompetent patients and treatment of recurrent mucocutaneous herpes simplex infections in HIV infected patients.

Mechanism Of Action:
Famciclovir undergoes rapid biotransformation to the active antiviral compound penciclovir, which has inhibitory activity against herpes simplex virus types 1 (HSV-1) and 2 (HSV-2) and varicella zoster virus (VZV). In cells infected with HSV-1, HSV-2 or VZV, viral thymidine kinase phosphorylates penciclovir to a monophosphate form that, in turn, is converted to penciclovir triphosphate by cellular kinases. In vitro studies demonstrate that penciclovir triphosphate inhibits HSV-2 DNA polymerase competitively with deoxyguanosine triphosphate. Consequently, herpes viral DNA synthesis and, therefore, replication are selectively inhibited.

News Articles on Famciclovir

Herpes healing comes in numbers  -  ‎Aug 4, 2009‎
Treatment: Daily suppression medications like Valtrex, Famvir and Acyclovir can reduce the severity and frequency of outbreaks, or blisters that can spread CharlotteObserver.com

Quicker cold sore relief?  -  ‎Jun 27, 2009‎
The pills are oral acyclovir (Zovirax), famciclovir (Famvir) and valacyclovir (Valtrex).]The ointments are penciclovir (Denavir) or acyclovir cream. KXXV News Channel 25

Liver disease and HIV  -  ‎Apr 14, 2009‎
Several previous clinical studies have assessed the efficacy of other medications such as lamivudine (3TC, Epivir), famcyclovir (Famvir) and adefovir ADVANCE for Physician Assistants

Shingles more painful in elderly  -  ‎Apr 6, 2009‎
We give patients acyclovir, famvir and valacycovir. They are FDA-approved anti-viral drugs that decrease the shedding of the virus, shorten the life span of Baltimore Sun

People's Pharmacy: Vitamin D a shining star  -  ‎Apr 5, 2009‎
A. Prescription antiviral drugs such as Valtrex or Famvir can be helpful against shingles. Many people say that L-lysine works for cold sores. Houston Chronicle

Natural treatments for shingles  -  ‎Apr 9, 2009‎
Conventional medical treatment of shingles includes antiviral medications, such as acyclovir (Zovirax), valacyclovir (Valtrex), and famciclovir (Famvir). Examiner.com

Liver Disease and HIV  -  18 Mar 2009
Several clinical studies have assessed the efficacy of medications such as lamivudine (3TC, Epivir), famcyclovir (Famvir) and adefovir (Preveon) and ADVANCE for LPNs

Teva Loses Bid To Toss Novartis Claims Over Famvir  -  ‎Feb 26, 2009‎
Teva Pharmaceuticals USA Inc. or grant the generics maker summary judgment in a patent dispute with Novartis AG over the genital herpes drug Famvir. IP Law360 (subscription)

Can herpes carrier have safe sex?  -  ‎Mar 2, 2009‎
If my partner wears a condom and I'm on suppressive therapy (Famvir), how safe will it be? A: Antiviral medications like Famvir and Valtrex diminish herpes Seattle Times

Markets in Brief  -  ‎Mar 1, 2009‎
...subsidiary a summary judgment in a patent dispute with rival Novartis over the genital herpes drug famcyclovir, sold under the brand name of Famvir. Ha'aretz

Buy famvir  -  Jan 17, 2009
Consultation phentermine xenical non online buy famvir xenical buy buy famvir women pennies dolars long. buy ritalin treat cheap buy famvir buy it cheap 90 Griggs County Courier,

What treatments work for cold sores?  -  Jan 21, 2009
Other antiviral medicines include famciclovir (Famvir) and valaciclovir (Valtrex). If you cannot swallow tablets or if the prescription is for a baby or guardian.co.uk,

Novartis Drops as Profit Disappoints, Vaccine Delayed  -  Jan 28, 2009
Sales of five products, including the Famvir herpes medicine and the irritable bowel treatment Zelnorm had fallen by almost half to $1.7 billion from 2006 Bloomberg

Research and Markets: Novartis: Performance - Products - Pipeline ...  -  Feb 3, 2009
Zometa (for hypercalcaemia of malignancy and bone metastases), the blood pressure treatment Lotrel and Famvir, the antiviral drug for treating herpes, Trading Markets (press release),

Herpes Zoster Alert  -  Jan 15, 2009
The two newer agents are famciclovir (Famvir) and valacyclovir (Valtrex). Acyclovir (Zovirax), the oldest agent, differs from the other drugs in that it ADVANCE for Physician Assistants,

Novartis increases dividend by 25% based on strong 2008 results ...  -  Jan 27, 2009
Cost of Goods Sold fell 1.6 percentage points to 17.0% of net sales, primarily reflecting the 2007 impairment charge of USD 320 million for Famvir. Trading Markets (press release),

Dank solider Ergebnisse des -6-  -  Jan 27, 2009
17,0% des Nettoumsatzes zurück, was hauptsächlich auf den Aufwand von USD 320 Millionen für die Wertminderung von Famvir im Vorjahr zurückzuführen war. Ad-Hoc-News (Pressemitteilung),

Novartis augmente son dividende de 25% -6-  -  Jan 27, 2009
...pourcentage à 17,0% du chiffre d'affaires net, reflétant principalement des charges pour perte de valeur d'USD 320 millions pour Famvir passée en 2007. Ad-Hoc-News (Pressemitteilung),

Hiatal hernia turns traumatic  -  Dec 17, 2008
I received the drug Famvir at the start. Now I take Lyrica and Percocet. I am miserable. How long is recovery? I have a mild case. Payson Roundup,

US Federal Trade Commission Clears Teva’s Acquisition of Barr  -  Dec 19, 2008
Neurontin®, Lotrel®, Famvir® and Protonix®, Teva's and Barr's ability to successfully develop and commercialize additional pharmaceutical products, WELT ONLINE,

New vaccine policy recommended for older Americans  -  Dec 9, 2008
Famciclovir (Famvir) is another antiviral. Regardless of which one is prescribed, the antiviral medications are most effective if they’re taken as soon as Buffalo News,

Doin’ It With Dr. V: Cold Sores  -  Nov 30, 2008
If they come a knocking more than that, you can talk to your doctor about other treatment options, medications like Zovirax®, Valtrex®, and Famvir®, The Frisky,

Teva and Barr Provide Update on Acquisition  -  Oct 27, 2008
Neurontin®, Lotrel®, Famvir® and Protonix®, Teva's and Barr's ability to successfully develop and commercialize additional pharmaceutical products, WELT ONLINE,

Novartis posts 32% net profit gain  -  21 Oct 2008
...products the like blood pressure tablet Lotrel and the herpes treatment Famvir, as well as the withdrawal of bowel drug Zelnorm in the United States. International Herald Tribune,

Novartis reporta crecimiento 32 pct en ganancias netas 3er trim  -  21 Oct 2008
...contra la presión sanguínea Lotrel y el tratamiento contra el herpes Famvir, así como el retiro del medicamento intestinal Zelnorm en Estados Unidos. Reuters América Latina,

Novartis Q3 profit seen up 34 pc  -  Oct 14, 2008
Novartis was hit in the third quarter of 2007 by generic competition to products like blood pressure tablet Lotrel and herpes treatment Famvir, Economic Times,

Novartis International AG (SWF:NOVN) Novartis Delivers Sustained ...  -  Oct 19, 2008
Cost of Goods Sold improved 1.5 percentage points largely due to a one-time charge of USD 320 million in the 2007 period for a partial impairment of Famvir ABN Newswire (press release),

EARNINGS PREVIEW: European Drug Cos 3Q To Offer Few Catalysts  -  Oct 14, 2008
...negative effects from generic competition to Lotrel, Trileptal, Lamisil and Famvir, as well as the withdrawal of Zelnorm, should have run their course. EasyBourse.com,

Genital Herpes Virus Infects 28% of Women by Age 49 (Update2)  -  Oct 2, 2008
Antiviral medicines such as GlaxoSmithKline Plc's Valtrex and Zovirax and Novartis AG's Famvir can shorten and stave off outbreaks. The medicines don't kill Bloomberg

Single-Day Famciclovir Effective as 3-Day Valacyclovir for Genital ...  -  Sep 24, 2008
Novartis, which makes famciclovir under the brand name Famvir, supported this study and employs one of the study authors. The other study authors have Medscape (subscription)

Trotz Gewinnsprung baut Novartis Management wieder um  -  Oct 20, 2008
...als Konkurrenz durch Nachahmermedikamente auf die Verkäufe des Blutdrucksenkers Lotrel und des Herpes-Medikaments Famvir gedrückt hatten und der Konzern Reuters Deutschland,

DJ HUGIN NEWS/Novartis erzielt in den ersten neun -6-  -  Oct 19, 2008
Dies war hauptsächlich auf einen einmaligen Aufwand von USD 320 Millionen für eine partielle Wertminderung von Famvir im Vergleichszeitraum 2007 Ad-Hoc-News (Pressemitteilung),

Hugin-News: Novartis International AG  -  Oct 19, 2008
Aufgrund der soliden Geschäftsexpansion, den von USD 320 Millionen für eine partielle Wertminderung von Famvir im von Diovan (USD 1,4 Milliarden, WELT ONLINE,

DJ HUGIN NEWS/Novartis réalise une excellente -7-  -  Oct 19, 2008
...des ventes de quatre produits (Lotrel, Lamisil, Trileptal et Famvir) confrontés à la concurrence de génériques ainsi que de la suspension de Zelnorm. Ad-Hoc-News (Pressemitteilung),

El virus del herpes genital ataca al 28 por ciento de las mujeres ...  -  Oct 8, 2008
Los fármacos antivirales como Valtrex y Zovirax, de GlaxoSmithKline Plc , y Famvir, de Novartis AG, pueden acortar y eliminar los brotes. Impulso Baires,

Novartis sues Israel's Teva over patents  -  Jul 28, 2008
Novartis has already gone before the US courts to fight the introduction of generic versions of its drug Famvir for treating genital herpes and Lotrel for AFP

Medicine's effective for most with bipolar disorder  -  Jul 23, 2008
I received the drug Famvir at the start. Now I take Lyrica and Percocet. I am miserable. How long is recovery? I have a mild case. Kilgore News Herald,

What are Shingles?  -  Jul 9, 2008
Examples of antiviral drugs used to treat shingles include acyclovir (Zovirax®), valcyclovir (Valtrex®), or famcyclovir (Famvir®). KARE,

Teva Completes Acquisition of Bentley Pharmaceuticals  -  Jul 23, 2008
Lotrel(R), Famvir(R) and Protonix(R), Teva's and Barr's ability to successfully develop and commercialize additional pharmaceutical products, FOXBusiness

Teva Enrolls Patients for a Second Large Global Phase III Trial of ...  -  Jul 15, 2008
Neurontin®, Lotrel®, Famvir® and Protonix®, Teva’s ability to successfully develop and commercialize additional pharmaceutical products, WELT ONLINE,

Teva Comments on Paragraph IV Filing for COPAXONE(R); Intends to ...  -  Jul 11, 2008
Neurontin(R), Lotrel(R), Famvir(R) and Protonix(R), Teva's ability to successfully develop and commercialize additional pharmaceutical products, MarketWatch

Novartis Finds Defense in Alcon  -  Jul 8, 2008
US sales of five of Novartis' products -- Zelnorm, Lotrel, Trileptal, Lamisil and Famvir -- accounted for $3.1 billion in sales in 2006, but only $1.7 TheStreet.com

Novartis Gains Momentum With Strong Performance In First Half Of ...  -  Jul 16, 2008
...which was caused by the 2007 generic entries for four products (Lotrel, Lamisil, Trileptal and Famvir) and the Zelnorm suspension. ABN Newswire (press release),

Nurse practitioner a viable health care option  -  Jul 14, 2008
There are several medications to treat it, such as antivirals (Famvir and others), nerve blockers (Neurontin, etc.) and pain medication (Ultracet, GoErie.com,

Novartis gains momentum with strong performance in first half of ...  -  Jul 16, 2008
11% decline in the US, which was caused by the2007 generic entries for four products (Lotrel, Lamisil, Trileptaland Famvir) and the Zelnorm suspension. Ad-Hoc-News (Pressemitteilung),

Novartis: Klage gegen israelischen Generikahersteller Teva  -  Jul 28, 2008
Novartis hat in der Vergangenheit in den USA gegen Teva unter anderem bereits Klagen gegen die Markteinführung von Generika für das Medikament Famvir (gegen Swissinfo,

Novartis: plainte contre l'israélien Teva, litige sur des brevets  -  Jul 28, 2008
Novartis avait déjà contesté devant la justice aux Etats-Unis l'introduction de versions génériques du Famvir (herpès génital) et du Lotrel (hypertension) Romandie.com,

Teva to Acquire Barr  -  Jul 18, 2008
Lotrel(R), Famvir(R) and Protonix(R), Teva's and Barr's ability to successfully develop and commercialize additional pharmaceutical products, PR Newswire (press release),

HUGIN NEWS/Novartis gewinnt an Dynamik und -2-  -  Jul 16, 2008
Die rückläufige Entwicklung in den USA ist auf die Einführung von Generikakonkurrenz für vier Produkte (Lotrel, Lamisil, Trileptal und Famvir) im Jahr 2007 FOCUS Online,

DJ HUGIN NEWS/Novartis: accélération au premier -5-  -  Jul 17, 2008
Etats-Unis et provoquée par l'arrivée de génériques de quatre produits (Lotrel, Lamisil, Trileptal et Famvir) et par la suspension de Zelnorm en 2007. cecu.de,

Novartis: accélération au premier semestre 2008, avec une ...  -  Jul 16, 2008
Etats-Unis et provoquée par l'arrivée de génériques de quatreproduits (Lotrel, Lamisil, Trileptal et Famvir) et par la suspensionde Zelnorm en 2007. Ad-Hoc-News (Pressemitteilung),

Teva Receives First US Approval For Generic Risperdal(R) Tablets ...  -  03 Jul 2008
Neurontin®, Lotrel®, Famvir® and Protonix®, Teva's ability to successfully develop and commercialize additional pharmaceutical products, Medical News Today (press release),

Management of Herpes Simplex Infections Reviewed  -  Jun 12, 2008
One of the review authors has received honoraria for speaking engagements from Novartis (maker of famciclovir [Famvir]) and GlaxoSmithKline (maker of Medscape (subscription)

Understanding Genital Herpes  -  Jun 3, 2008
Your health care provider may recommend you anti-viral medication (aciclovir (Zovirax), famciclovir (Famvir) and valaciclovir (Valtrex), which will reduce TheMedGuru,

Business news in brief  -  Jun 10, 2008
...won an appeals court decision that would let it keep selling a lower-cost version of Novartis AG's Famvir treatment for genital herpes. Philadelphia Inquirer,

Avoiding shingles  -  Jun 2, 2008
Similar drugs, such as Valtrex or Famvir, can also be used. These drugs may also help stave off the painful aftereffects of shingles known as postherpetic Daily News Transcript,

Betsy Wadland: Avoiding shingles as an adult  -  02 Jun 2008
Similar drugs, such as Valtrex or Famvir, can also be used. These drugs may also help stave off the painful aftereffects of shingles known as postherpetic Norwich Bulletin,

Teva Announces Launch Of Generic Wellbutrin XL(R) Tablets, 150 Mg  -  02 Jun 2008
Neurontin®, Lotrel®, Famvir® and Protonix®, Teva's ability to successfully develop and commercialize additional pharmaceutical products, Medical News Today (press release),

Shingles: Treatment and prevention  -  May 23, 2008
Such medications include acyclovir (Zovirax), valacyclovir (Valtrex) or famciclovir (Famvir). The medicines work best when given within the first 72 hours Scotts Valley/San Lorenzo Valley Press-Banner,

It's Official: Get Your Shingles Vaccination  -  May 16, 2008
The prescription antiviral medications acyclovir (Zovirax), valacyclovir (Valtrex), and famciclovir (Famvir), are used to treat shingles, but they should be U.S. News & World Report,

Sector Snap: Goldman looking for Teva patent suit updates  -  May 5, 2008
...patent on oral contraceptive Yasmin, and the trial for Novartis' Famvir herpes drug _ which Teva launched an at-risk generic version of in September. CNNMoney.com

Vaccine for shingles suggested for anyone over 60  -  May 15, 2008
Anti-viral medication, including Zovirax, Valtrex and Famvir, should be taken within 72 hours of onset to reduce symptoms, Ms. Williams said. Pittsburgh Post Gazette,

* Novartis on track in 2008:  -  Apr 20, 2008
These products - Zelnorm, Lotrel, Trileptal, Lamisil and Famvir - had combined total net sales in the US of USD 3.1 billion in 2006, and net sales for this Market Wire (press release)

Problems with low cholesterol pop up  -  Apr 20, 2008
Your doctor could prescribe acyclovir (Zovirax), famciclovir (Famvir) or valacyclovir (Valtrex). You should not worry about the pharmacy where you purchase Houston Chronicle,

Early Treatment with COPAXONE(R) Significantly Delayed Progression ...  -  Apr 17, 2008
Neurontin(R), Lotrel(R), Famvir(R) and Protonix(R), Teva's ability to successfully develop and commercialize additional pharmaceutical products, FOXBusiness

Novartis reports higher sales and  -  Apr 20, 2008
These products - Zelnorm, Lotrel, Trileptal,Lamisil and Famvir - had combined total net sales in the US of USD3.1 billion in 2006, and net sales for this Ad-Hoc-News (Pressemitteilung),

A New Fibromyalgia Remedy: Antiviral Drugs  -  Apr 11, 2008
Control the viruses using the antiviral drugs famciclovir (brand name Famvir) or valacyclovir (Valtrex). What we find in these people who have active U.S. News & World Report,

Novartis Q1 earnings beat forecasts, confirms outlook UPDATE  -  Apr 20, 2008
These products, Zelnorm, Lotrel, Trileptal, Lamisil and Famvir, had combined sales of $1.7 billion in 2007. The year-on-year impact of lost sales will only CNNMoney.com

Teva Provides Update on Generic Aricept(R) Litigation  -  Mar 28, 2008
Neurontin®, Lotrel®, Famvir® and Protonix®, Teva's ability to successfully develop and commercialize additional pharmaceutical products, WELT ONLINE,

COPAXONE(R) Significantly Reduced Brain Atrophy and Tissue Loss ...  -  Apr 17, 2008
Neurontin ® , Lotrel ® , Famvir ® and Protonix ® , Teva's ability to successfully develop and commercialize additional pharmaceutical products, Earthtimes,

Brand Names/Synonyms:
Famvir is also known by the following brand names and/or synonymsCHEMBANK1696; FCV; Famciclovir; Famciclovir 98.5; Famciclovir [Usan:Ban:Inn]; Famciclovirum [Inn-Latin]; Famvir

Drug Category:
Famvir is categorized under the following by the FDA: Prodrugs; Antivirals; Nucleosides and Nucleotides (08:18.32); ATC:J05AB09; ATC:S01AD07

Dosage Forms:
Tablet

Absorption:
77%

Interactions:
Interactions for Famciclovir:

Concurrent use with probenecid or other drugs significantly eliminated by active renal tubular secretion may result in increased plasma concentrations of penciclovir.

The conversion of 6-deoxy penciclovir to penciclovir is catalyzed by aldehyde oxidase. Interactions with other drugs metabolized by this enzyme could potentially occur.





Chemical IUPAC Name:
[2-(acetyloxymethyl)-4-(2-aminopurin-9-yl)-butyl] acetate

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