Endocet

This page contains recent news articles, when available, and an overview of Endocet but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Endocet
(when available)

Pharmacology and use:
Oxycodone, a semisynthetic opiate agonist derived from the opioid alkaloid, thebaine, is similar to other phenanthrene derivatives such as hydrocodone and morphine. Oxycodone is available in combination with aspirin or acetaminophen to control pain and restless leg and Tourette syndromes. For the treatment of diarrhoea, pulmonary oedema; For the relief of moderate to moderately severe pain

Mechanism Of Action:
Oxycodone acts as a weak agonist at OP1, OP2, and OP3 opiate receptors within the central nervous system (CNS). Oxycodone primarily affects OP3 receptors, which are coupled with G-protein receptors and function as modulators, both positive and negative, of synaptic transmission via G-proteins that activate effector proteins. Binding of the opiate stimulates the exchange of GTP for GDP on the G-protein complex. As the effector system is adenylate cyclase and cAMP located at the inner surface of the plasma membrane, opioids decrease intracellular cAMP by inhibiting adenylate cyclase. Subsequently, the release of nociceptive neurotransmitters such as substance P, GABA, dopamine, acetylcholine, and noradrenaline is inhibited. Opioids such as Oxycodone also inhibit the release of vasopressin, somatostatin, insulin, and glucagon. Opioids close N-type voltage-operated calcium channels (OP2-receptor agonist) and open calcium-dependent inwardly rectifying potassium channels (OP3 and OP1 receptor agonist). This results in hyperpolarization and reduced neuronal excitability.

News Articles on Oxycodone

Waldo County grand jury indicts 40  -  ‎Aug 18, 2009‎
Baker is also accused of entering a residence in Brooks March 29 and illegally taking a scheduled drug (Endocet) and assorted US currency. VillageSoup Belfast

Area Arrests  -  ‎Jul 7, 2009‎
Quinton Dominique Sims, 21, 1271 Piney Ridge Road SE, Dalton, was charged Monday by the Whitfield County Sheriff's Office with possession of endocet and Daily Citizen

FDA May Restrict Acetaminophen  -  ‎Jul 1, 2009‎
Some brand-name pain prescriptions containing acetaminophen include Vicodin, Lortab, Maxidone, Norco, Zydone, Tylenol with codeine, Percocet, Endocet, WebMD

Mahopac man charged with burglarizing doctor's office, stealing ...  -  ‎Jul 7, 2009‎
...forging two other prescription forms by signing the doctor's name and taking them to a pharmacy where he obtained 120 Oxycodone and 120 Endocet pills. Mid-Hudson News

Drugs seized in Moore County arrest  -  ‎Jun 27, 2009‎
During the search, deputies seized about 230 prescription pills, including Percocet, Lorcet Plus, MS Contin and Endocet, the release said. FayObserver.com

BUYINS.NET: ENDP, VRUS, RDY, TEO, SAPE, DT. Top Gainers With ...  -  ‎Jun 17, 2009‎
The companys generic products include Morphine Sulfate and Endocet, an oxycodone hydrochloride and acetaminophen product. It has strategic alliances with TMC Net

Les É-U pourraient retirer les antidouleurs combinés au ...  -  ‎Jul 3, 2009‎
Tylénol avec codéine, Percocet, Endocet et Darvocet. L'adoption de cette recommandation bouleverserait de façon importante le traitement de la douleur, PsychoMédia

Mt. Pleasant woman pleads guilty in 2007 fatal crash in Uniontown  -  ‎Apr 15, 2009‎
Stewart told police she had prescriptions for oxycodone, Endocet and amitriptyline. According to the National Institutes of Health online Web site, Pittsburgh Tribune-Review

Buckingham Research Maintains a 'Neutral' on Endo Pharma (ENDP ...  -  ‎Apr 16, 2009‎
KV's manufacturing problems have led to dramatic growth in Endo's morphine sulfate painkiller while the Endocet painkiller has grown strongly as well due to StreetInsider.com (subscription)

Sheriff’s office  -  ‎Apr 7, 2009‎
Trafficking in drugs, possession of drugs — State Route 243 at Private Drive 3467, South Point Saturday, vicodin, percocet, endocet, morphine and other Ironton Tribune

Cherry Hill pharmacist faces drug charges  -  ‎Mar 12, 2009‎
According to the indictment filed Tuesday, from 2001 through October 2006, Lawrence Young, 68, sold thousands of pills of Xanax, Endocet, and other Philadelphia Inquirer

Police accuse Bethlehem couple of packaging crack cocaine in their ...  -  ‎Mar 5, 2009‎
Police said the marijuana and Endocet were kept within reach of the children. The home also contained an unspecified amount of cash, police said. The Express Times - LehighValleyLive.com

NEW CASTLE COUNTY  -  ‎Mar 1, 2009‎
He was arrested about 3:10 pm with 30 Endocet pills. Endocet contains acetaminophen and oxycodone and is used to relieve moderate to severe pain. The News Journal

Johnson City man, his wife and brother charged in drug bust at home  -  ‎Feb 19, 2009‎
At the time of their arrest, narcotics agents located over 100 pills of different types including Oxycontin, Suboxone, Xanax, Endocet, Lortabs and Diazepam. Kingsport Times News

Springfield detectives nab four in two drug raids  -  ‎Mar 11, 2009‎
...possession of marijuana with intent to distribute, possession of oxycodone, possession of Endocet, and violating a drug-free school zone. The Republican - MassLive.com

Laconia District Court  -  ‎Mar 12, 2009‎
...of the controlled or narcotic drugs Klonipin, Flexeral, Fiortal and Endocet and the cases were bound over to Superior Court for possible indictment. Laconia Citizen

Zanesville man pleads not guilty to rape charges  -  ‎Mar 5, 2009‎
...two counts of possession of Oxycodone, three counts felonies in the fifth-degree of illegal processing of drugs, one count of possession of Endocet, Zanesville Times Recorder

Thief takes Macbeth book: "What's done is done"  -  ‎Mar 5, 2009‎
Bermuda Road: Police confiscated a bong, two bags of marijuana, 10 Hydrocodone pills, seven Endocet pills, four morphine pills, four Alprazolam pills and al.com

Endo Pharma Q4 Profit Rises - Update  -  ‎Feb 27, 2009‎
Net sales from the company's generic products, which includes Endocet, Endodan and Zydone, were $24.1 million, compared to $19.2 million in the prior year Trading Markets (press release)

Two charged with drug violations  -  Feb 3, 2009
Investigators found $536 along with 64 dosage units of crack cocaine, the painkiller Endocet and Valium and a small amount of marijuana, the release said. FayObserver.com,

Trooper faces charges over painkillers  -  Jan 27, 2009
The drugs he allegedly obtained included oxycodone and hydrocodone and other similar drugs, such as endocet, tramadol, and fentanyl, according to court Boston Globe,

Scioto Couple Arrested on Drug Charges  -  Jan 22, 2009
Deputies say inside the house they found Oxycontin, Oxycondeon, Methadone, Vicodin, Lorcet, Xodol, Suboxone, Endocet and drug paraphernalia. WSAZ-TV,

New Paltz man charged with illegal sale of pills  -  Jan 15, 2009
Town police said Madison Shearer, 31, was intercepted as he was driving to a New Paltz location to sell Xanax and Endocet. Town police and the Ulster County Times Herald-Record,

Man sentenced to two years  -  Jan 13, 2009
29, 2007 to Oct. 17, 2007, Moore deceived the hospital to obtain Endocet, another pain reliever. On Monday in Fayette County Common Pleas Court, Record Herald,

New Paltz man charged with selling prescription narcotics  -  Jan 16, 2009
Madison Shearer was intercepted as he was driving to a New Paltz location to sell a quantity of Xanax and Endocet and was taken into custody without Mid-Hudson News,

Out-of-towners arrested on drug charges  -  Jan 13, 2009
David Zachery Fields, of West Virginia, was also arrested on charges of possessing Oxycodone and Endocet by the Woodfin Police. The 44-year-old was held on Asheville Citizen-Times,

Three arrested in Scioto Co. drug raid  -  Jan 23, 2009
...oxycodone, methadone, Vicodin, Lorcet, Xodol, Suboxone, Endocet and drug paraphernalia. Also arrested at the scene was 31-year-old Summer Catrell, Chillicothe Gazette,

Police & court briefs  -  Jan 16, 2009
NEW PALTZ - A New Paltz man has been charged after police say he was found with Xanax and Endocet he intended to sell. Madison Shearer, 32, of Olev Lane, Poughkeepsie Journal,

Police Beat for December 14  -  Dec 14, 2008
Officers executed a search warrant on an Edgewater home Thursday, which led to the recovery more than $1200 worth of Oxycontin, Endocet and other pills, Annapolis Capital,

Grocery store pharmacist charged with stealing drugs  -  Dec 2, 2008
Other drugs on the evidence list are Ativan, Diazepam, Endocet, Focalin, Methylin, Alprazolam, and Oxycodone. “He was a pharmacist for Ingles Market in News Record and Sentinel,

Police Reports  -  Dec 18, 2008
When stopped Smith appeared confused and disoriented, police said, adding that she said she had taken Endocet earlier in the day. She failed several field Valley Item,

Can of beer nets suspect in robbery  -  Dec 9, 2008
100 tablets of Endocet, which is a combination of oxycodone and acetaminophen, and about 400 tablets of morphine sulfate, according to police reports. Bangor Daily News,

Collier County Police Briefs: Dec. 8, 2008  -  Dec 7, 2008
He was charged with possession of a controlled substance, Endocet. Sean Andrae Singleton, 33, 700 105th Ave. N., North Naples, was arrested Friday at 720 Naples Daily News,

Man robbed while walking down street  -  Nov 19, 2008
...the theft of her prescription medication from her home, including Diazepam, Endocet and Skelaxin (valium, pain medication and a muscle relaxer). Richmond Register,

Cops nab alleged burglar with aid of postal worker  -  Oct 27, 2008
Heidler had in his possession a bottle containing 355 Endocet pills. Endocet is a generic version of Percocet, a painkiller, Miller said. The Tribune-Democrat,

Two Charged in Sale of Prescription Drugs to WCPD Detective  -  Oct 29, 2008
YONKERS, NY -- Two Manhattan men were arrested Friday night, October 24, 2008, after they offered to sell nearly 200 Endocet pills to an undercover officer Yonkers Tribune,

Posted By BOB VAILLANCOURT, THE SUDBURY STAR  -  Nov 4, 2008
One bottle contained morphine sulfite tablets, while the other had endocet tablets. Hospital staff saw Deguire leave the hospital and get on a Sudbury Sudbury Star,

Lee deputies arrest man on prescription drugs fraud charges  -  Oct 9, 2008
7, it was learned Champ was obtaining large quantities of Hydrocodone, Oxycodone, Percocet, Xanax, Endocet, Morphine and Alprazolam from at least 10 The News-Press,

4 Arrested In New Haven Drug Bust  -  Oct 8, 2008
Police also seized from the residence approximately 5.75 ounces of Marijuana, approximately 2 grams of cocaine, 412 pills -- assorted Endocet, Oxycodone, WFSB,

Cocaine, pills seized from vehicle  -  Oct 7, 2008
Cocaine, oxycocet and endocet were found inside the vehicle, police said. Jacey Bedore, of Ennismore, is charged with possession of a controlled substance Peterborough Examiner,

Police Beat  -  Oct 17, 2008
Kenneth Color (James), 48, homeless, charged with possession of a Schedule II drug (endocet and Oxycodone) and possession of a Schedule II drug (dolophine Opelousas Daily World,

Two charged in painkiller heist  -  Aug 28, 2008
As he entered the store, Smith said McKellak put on a mask and demanded specific pain-killing drugs such as endocet, hydrocodone and loritab. Roanoke Rapids Daily Herald,

Two plea guilty to delivery of drugs  -  Sep 4, 2008
Sparks noted that Oxycodone is more commonly known by the trade names, Oxycontin, Tylox, Percocet and Endocet. Ferrell is exposed to confinement in a state Williamson Daily News,

Medical Watch: Top 7 Most Dangerous Drugs  -  Jul 24, 2008
Going by the generic name Endocet, even the FDA says they can cause the body to slow down and hinder breathing when taken in excess. News Channel 7,

Duo Arrested on Multiple Counts of Forgery, Identity Theft  -  Jul 18, 2008
According to investigators, the controlled substances obtain included Percocet, Tussionex, Xanax and Endocet. Both subjects were arrested and released on WBOC TV 16,

Tallahassee couple arrested on 'doctor shopping' charges  -  Jul 15, 2008
...the same medical complaints and got 68 prescriptions for Hydrocodone, Oxycodone, Endocet and Darvocet, amounting to about 3000 pills, according to FDLE. Tallahassee Democrat,

Medicated to Death: Painkillers Kill More Than All Drugs Combined  -  Jul 10, 2008
The war on drugs in Port St. Lucie is now focused on Oxycontin, Endocet, Percocet, Methadone, Xanex, Hydrocodone. Attached to that long list of drugs is WPEC,

Police recover loaded handgun after chasing teen through Fourth of ...  -  Jul 8, 2008
The magazine was loaded and one live round was in the chamber. When searching Folk, officers found a yellow tablet of Endocet, a controlled narcotic. Journal Times,

New Castle County  -  Jul 19, 2008
...from assorted drugstores, Hosfelt said. The drugs included Percocet, Xanax, Endocet and Tussionex. Both suspects were released on $75000 unsecured bail. The News Journal,

Tallahassee Couple Charged with Prescription Drug Fraud  -  Jul 15, 2008
...for treatment of the same medical complaints and obtained prescriptions for such pain medications as Hydrocodone, Oxycodone, Endocet and Darvocet. WCTV,

Gloucester District Court  -  Jul 11, 2008
Endocet, ibuprofen and hydrocodone. r A 21-year-old Gloucester man facing charges from three separate incidents pleaded guilty yesterday to resisting Gloucester Daily Times,

Traffic stop results in drug arrests  -  Jul 2, 2008
A search of the car yielded six pounds of marijuana and 1251 pills, including the painkillers methadone, Loritab and Endocet, in the trunk. Cincinnati.com,

Boone County Traffic Stop Yields Pot, Pills  -  Jul 1, 2008
During a search of the car, officers found six pounds of marijuana and more than 1200 pills, including Methadone, Loritab and Endocet. Burd and her in-law, WKRC TV Cincinnati,

Ky. Couple Charged With Drug Trafficking  -  Jul 1, 2008
A search of the vehicle revealed six pounds of processed marijuana and 1251 assorted pills, some of which were Methadone, Loritab and Endocet. WCPO,

KY Couple Accused of Trafficking  -  Jul 1, 2008
...say they found six pounds of marijuana, and more than 1200 individual pills, including Methadone, and opiate, and Endocet and Loritab, both narcotics. 700 WLW,

New Jersey fugitive caught in Cape Coral  -  Jun 25, 2008
Police also found a bag with nine Endocet pills in the area where Ollivierre was found, reports show. Ollivierre told police he had just taken one pill The News-Press,

Law firms ask to be released from representing Main Line couple  -  Jul 1, 2008
The drug charges he faces concern his filling prescriptions for patients for drugs like diazepam (the generic form of Valium), endocet (generic Percocet) Chester DailyLocal.com,

Man facing drug, weapons charges  -  Jun 10, 2008
Friday with possessing a shotgun while intending to distribute heroin, cocaine, Endocet, morphine, oxycodone and marijuana, according to authorities. Asbury Park Press,

Crawford enters Alford plea  -  Jun 4, 2008
Royse said a large quantity of Oxycodone and Xanax, a bottle full of Endocet, marijuana and drug paraphernalia were seized along with "several thousand Ledger Independent,

Brand Names/Synonyms:
Endocet is also known by the following brand names and/or synonymsCodeinone, Dihydrohydroxy-; Combunox; Dea No. 9143; Dihydrohydroxycodeinone; Dihydrohydroxycondeinone; Dihydrone; Dihydroxycodeinone; Dinarkon; Diphydrone; ENDOCET; ENDODAN; Endone; Eubine; Eubine [France]; Eucodal; Eucodalum; Eukodal; Eutagen; HSDB 3142; Ossicodone [Dcit]; Oxanest; Oxicodona [Inn-Spanish]; Oxicon; Oxicone; Oxikon; Oxycet; Oxycodeinone; Oxycodon; Oxycodone; Oxycodone Hcl; Oxycodone Hydrochloride; Oxycodone [Usan:Ban:Inn]; Oxycodonum [Inn-Latin]; Oxycon; Oxycontin; PERCOCET; Pancodine; Percobarb; Percocet; Percodan; Roxicet; Roxicodone; Roxilox; Supendol [Canada]; Tecodin; Tekodin; Thecodine; Thekodin; Tylox

Drug Category:
Endocet is categorized under the following by the FDA: Narcotics; Antitussives; Analgesics, Opioid; Opiate Agonists; ATC:N02AA05

Dosage Forms:
Tablet; Suppository

Absorption:
well absorbed from OxyContin® tablets with an oral bioavailability of 60% to 87%

Interactions:
Interactions for Oxycodone:

The CNS depressant effects of oxycodone hydrochloride may be additive with that of other CNS depressants..





Chemical IUPAC Name:
4, 5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one

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