Elavil

This page contains recent news articles, when available, and an overview of Elavil but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Elavil
(when available)

Pharmacology and use:
Protriptyline is a tricyclic antidepressant. It was thought that tricylic antidepressants work by inhibiting the re-uptake of the neurotransmitters norepinephrine and serotonin by nerve cells. However, this response occurs immediately, yet mood does not lift for around two weeks. It is now thought that changes occur in receptor sensitivity in the cerebral cortex and hippocampus. The hippocampus is part of the limbic system, a part of the brain involved in emotions. Presynaptic receptors are affected: a1 and b1 receptors are sensitized, a2 receptors are desensitised (leading to increased noradrenaline production). Tricyclics are also known as effective analgesics for different types of pain, especially neuropathic or neuralgic pain. A precise mechanism for their analgesic action is unknown, but it is thought that they modulate anti-pain opioid systems in the CNS via an indirect serotonergic route. They are also effective in migraine prophylaxis, but not in abortion of acute migraine attack. The mechanism of their anti-migraine action is also thought to be serotonergic. For the treatment of depression and obsessive-compulsive disorders

Mechanism Of Action:
Protriptyline acts by decreasing the reuptake of norepinephrine and serotonin (5-HT).

News Articles on Protriptyline

Ask Dr. H: Meralgia paresthetica, a pain in the thighs  -  20 Apr 2009
If the pain continues, medications like Neurontin, Tegretol, or Elavil can reduce the brain's perception of the chronic pain. If nothing helps, the last Philadelphia Inquirer

Noticing the Not-So-Obvious  -  20 Apr 2009
Older antidepressants such as imipramine (Tofranil) and amitriptyline (Elavil) can still be useful, although they generally have somewhat less favorable ADVANCE for Physician Assistants

police: ax used to kill actor Perryman  -  ‎Apr 6, 2009‎
...which is commonly used as an anti-convulsant and mood-stabilizing drug; Thorazine, used to treat schizophrenia; and Elavil, an anti-depressant. Austin American-Statesman

Report: Andrea Lee Mura died of drug overdose  -  ‎Apr 8, 2009‎
...of antidepressants: Fluoxetine, the generic form of Prozac; Nortriptyline, the generic form of Aventyl; and Amitriptyline, the generic form of Elavil. MLive.com

McCain Earmarks $50 million for Bigfoot Research  -  ‎Mar 31, 2009‎
His diabetic testing supplies along with his Allegra, Benadryl, Celebrex, Decadron, Elavil, Flomax, Gardasil, Humulin N, Ibuprofen, Januvia, Keppra, Glossy News (satire)

Certains antidépresseurs favoriseraient le diabète  -  ‎Apr 10, 2009‎
Le risque accru serait particulièrement élevé pour les antidépresseurs Deroxat (Seroxat ou Paxil, paroxétine) et pour l'Elavil (ou Endep, amitriptyline). PsychoMédia

Am Beispiel des Hummers  -  ‎Apr 10, 2009‎
Tofranil, Wellbutrin, Elavil, Metrazol, Nardil und Xanax, aber nichts davon konnte ihr das Leben auf Erden weniger schmerzhaft erscheinen lassen. ORF.at

Life and Letters The Unfinished  -  ‎Mar 2, 2009‎
Elavil, Metrazol in combination with unilateral ECT (during a two-week voluntary in-patient course of treatment at a regional Mood Disorders clinic), New Yorker

Killer Headache: Migraines Hike Stroke Risk  -  ‎Mar 2, 2009‎
She takes Elavil, an anti-depressant, for migraine prevention. She no longer takes oral contraceptives, and last year she had surgery to close a PFO doctors NBC Chicago

An assortment of drugs can be taken to treat RLS  -  Feb 1, 2009
I always try Elavil (Amitriptyline) as a first-line treatment for restless legs. The trick is to start at a low dose and gradually work up to the effective Hattiesburg American,

Depression in adults  -  Jan 21, 2009
Examples of TCAs (and their brand names) include amitriptyline (Elavil), nortriptyline (Allegron) and imipramine. SSRIs boost the amount of a chemical guardian.co.uk,

Other antidepressants  -  Jan 21, 2009
Examples include imipramine, nortriptyline (Allegron), amitriptyline (Elavil) and doxepin (Sinequan). TCAs are not recommended if you are breastfeeding. guardian.co.uk,

Manslaughter trial set for April  -  Jan 16, 2009
...on Wheels program and then took a shower before taking an unknown amount of the prescription anti-depressant Elavil in an unsuccessful suicide attempt. Colusa County Sun Herald,

Levine: Consumerism  -  Feb 1, 2009
...of the 20th century, psychiatrists thought they had found it with amphetamines, and later with tricyclic antidepressants like Tofranil and Elavil. ZNet,

Antidepressants Help Treat Fibromyalgia  -  Jan 13, 2009
The TCA amitriptyline (Elavil, Endep), given in low doses, had the largest effect on pain, fatigue, and sleep disturbances. Little effect was recorded on WebMD

Understanding Depression and antidepressant medications  -  Jan 24, 2009
...with examples including Elavil, Tofranil, and Pamelor, and Monoamine Oxidase Inhibitors, with examples including Nardil and Parnate. Daily Dunklin Democrat,

What treatments work for tinnitus?  -  Jan 21, 2009
...[2] The drugs that were used in studies were nortriptyline (Allegron), trimipramine (Surmontil) and amitriptyline (Elavil). People in two studies said the guardian.co.uk,

Treating post-traumatic stress disorder  -  Jan 21, 2009
Some of the most common ones (with their brand names) are amitriptyline (Elavil), imipramine, phenelzine (Nardil), mirtazapine (Zispin SolTab), guardian.co.uk,

The Military Family Network  -  Jan 15, 2009
Tricyclic antidepressants (TCAs): Examples are Elavil (amitriptyline), Tofranil (imipramine), and Pamelor (nortriptyline). Monoamine Oxidase Inhibitors eMilitary.org

Happy Feet Syndrome has nothing in common with RLS  -  Jan 11, 2009
I've had good luck with low doses of Elavil, a drug that literally costs less than the bottle you receive it in. Dr. Beaman has written weekly columns in Hattiesburg American,

What About Pain Pills and Similar Medications?  -  Jan 17, 2009
Another group of commonly used and abuse drugs in the United States are the Tri-Cyclic anti-depressants, or mood elevators, such as Elavil, Triavil, NewsReleaseWire.com (press release)

What Mg Is Xanax G3721  -  21 Nov 2008
...and is available in packs purple 1 mg xanax elavil xanax withdrawal symptoms xanax to sleep g3721 xanax xanax bars doseage what is lethal dose of xanax Cascade Policy Institute,

Dr. Marandiacute;a Fandeacute;lix-Ortiz: Therapy helped man break ...  -  Nov 18, 2008
My doctor prescribed Elavil, and as soon as I started taking the medicine, I lost the desire to drink. As long as I stayed on the medicine, I was fine. San Antonio Express,

Various rinses may help relieve burning mouth  -  Nov 11, 2008
When burning mouth fails to respond to the above, the medicines Klonopin, Elavil or Neurontin might help. Have your doctors looked for things like dry mouth SouthCoastToday.com,

Mistakes in Medication  -  Nov 11, 2008
Listed as sometimes appropriate are: Amitriptyline (Elavil), Doxepin (Sinequan), Indomethacin (Indocin), Diphenhydramine (Benadryl) and again, many more. Aiken Standard (subscription),

WV Man Indicted For 2001 Homicide  -  Nov 12, 2008
The investigation in 2001 revealed that Hornbaker was taking Oxycodone and Elavil for pain stemming from a 1995 car accident. Wednesday, Simpson said that Leesburg Today,

Lawsuit blames scientist's suicide on psychiatrist  -  Oct 18, 2008
The cause of death was determined to be multiple drug toxicity, resulting from a lethal overdose of Ambien and excessive amounts of Elavil, the complaint Trading Markets (press release),

What Ails You: Dealing with the challenge of chronic pain  -  Oct 5, 2008
In fact, it is antidepressant medications (Elavil, Paxil, Zoloft) managed by a psychiatrist which are the first line defense against neuropathic pain. Desert Dispatch,

Judge: Convicted murderer has right to make case for sentence ...  -  Oct 18, 2008
...was under the influence of a cocktail of medications at the time of the attacks, including Prozac, Vicodin, Xanax, Effexor and Elavil, prosecutors said. Woonsocket Call,

Antidepressant Drugs Raises Diabetes Risk by 30 percent  -  Oct 11, 2008
Drugs such as Elavil and Aventyl are in the older TCA family, first introduced in the 1950s. The newer SSRIs, including Prozac, Paxil and Zoloft, West Orlando News,

St. John's Wort Shown Effective for Major Depression  -  Oct 8, 2008
...typically at the minimum recommended, while those for maprotiline (Ludiomil) and amitriptyline (Vanatrip, Elavil, Endep) were slightly below guidelines. MedPage Today,

Older People in Danger from Common Drugs  -  Aug 28, 2008
Amitriptyline (Elavil) and doxepin (Sinequan) cause drowsiness, constipation, and urine retention. Shorter-acting citalopram (Celexa) paroxetine (Paxil) and NewsMax.com,

Critics: Don’t tie driver’s licence renewal to psychiatric history  -  Sep 10, 2008
...the xanax you pop at work the zoloft for the post -partum, the amitriptyline (Elavil) you take for migraines the paxil, the wellbutrin, the rivitrol and TheChronicleHerald.ca,

Xìu Tại Thuốc  -  Aug 29, 2008
Nhóm Tricyclic antidepressant như Amitriptyline (Elavil), Doxepin (Sinequan) và Imipramine (Tofranil): giảm libido, rối loạn cương dương, xáo trộn việc xuất Take2Tango

Couple in prison for death of girl, 5  -  07 Aug 2008
Leah died in February 2007, and autopsy results in May 2007 indicated she had ingested Elavil, a prescription anti-depressant drug that is used as a sleep Northeast Mississippi Daily Journal,

Grandparents sentenced in child's death  -  Aug 5, 2008
Authorities say the child, Leah Woods, died from an overdose of Elavil. On July 21, the Longs each pleaded guilty to culpable negligence manslaughter in the SunHerald.com,

Police briefs: Cops find cocaine in Broadway apartment  -  Jul 31, 2008
25.5 Inderal, two Flexeril, nine Glynase Prestab, 26 Adderall, 11 Elavil and an assortment of undetermined pills, including 10 small white tablets, Cambridge Chronicle,

MSP Reports for Calvert County  -  Jul 10, 2008
A search revealed several Elavil pills which were improperly packaged and labeled. Khan was transported to the Prince Frederick Barrack for processing. Southern Maryland Online,

Stress Urinary Incontinence: An Overview of Diagnosis and ...  -  Jul 23, 2008
...as oxybutynin (Ditropan(R)) and tolterodine (Detrol(R)), and tricylic antidepressants such as amitriptyline (Elavil(R)) and imipramine (Tofranil(R)). RedOrbit,

Caraco Pharma: FDA approves generic version of AstraZeneca's Elavil  -  Jun 30, 2008
Laboratories Ltd. said Monday the Food and Drug Administration has granted final approval of its generic version of AstraZeneca's antidepressant Elavil. Forbes,

Caraco Pharma gets FDA Approval to Market Generic Version of Elavil  -  Jun 30, 2008
According to IMS Data, for the twelve months ended March 2008, Amitriptyline Hydrochloride USP Tablets, marketed under the brand name of Elavil, had annual RTT News,

Caraco Pharmaceutical Laboratories, Ltd. Announces FDA Approval to ...  -  Jun 30, 2008
It is marketed under the brand name of Elavil(R), a registered trademark of AstraZeneca. Daniel H. Movens , Caraco's Chief Executive Officer, said, Earthtimes (press release),

CPD: FDA Approval to Market Generic Version of Elavil(R)  -  Jun 30, 2008
It is marketed under the brand name of Elavil(R), a registered trademark of AstraZeneca. KNOBIAS DISCLAIMER: All statements made in this article were made Trading Markets (press release),

Marijuana in Prison  -  Jun 9, 2008
Back when I first came to prison, I tried Elavil, Xanax and Valium to relieve stress. They all worked in varying degrees of effectiveness but I did not like PR CannaZine (press release),

People With Dementia Should Avoid Certain Drugs  -  Jun 27, 2008
Antidepressants Tricyclic Antidepressants, such as Amitriptyline (Elavil), Amoxapine (Asendin), Clomipramine (Anafranil), Doxepin (Sinequan), RedOrbit,

Mental patient's death ruled a suicide  -  Jun 26, 2008
Though Jones told the staff he wasn't well enough to leave, he was told to pack and given a bottle with 28 pills of the antidepressant Elavil to take after News & Observer,

Man convicted in wife's overdose death gets 11 extra years  -  Jun 25, 2008
The antidepressants Prozac, Elavil and Pamelor or Aventyl were found in her system. Kevin Wootan told police she also was addicted to Valium and a marijuana Leader-Telegram,

Market Report -- In Play (CPD)  -  Jun 30, 2008
Caraco Pharma announces FDA approval to market generic version of Elavil Co announces that the US Food and Drug Administration has granted final approval MSN Money

Military Update: Disabled soldier returning to war, facing ‘stop loss’  -  Jun 20, 2008
He takes the drug Tramadol for his migraine headaches and Elavil, an anti-depressant, to ease his stress. Adding to Haun's stress is this surprising news: Coalinga Record,

Depression and Pain  -  Jun 16, 2008
Antidepressants, especially the tricyclic amitriptyline (Elavil), venlafaxine (Effexor), and duloxetine (Cymbalta) can treat pain/depression because they Nurse.com,

Give brain mental, sensory tasks  -  Jun 10, 2008
These "anticholinergic" medications include some older antidepressants like Elavil, as well as some antihistamines, painkillers, muscle relaxants, Arizona Daily Star,

Migraine headache often under-diagnosed and under-treated?  -  Jun 20, 2008
Medications with the longest history of use are propranolol (Inderal), a beta blocker, and amitriptyline (Elavil), an antidepressant. Cameroon Radio Television,

Illegal US Online Drug Sales  -  May 23, 2008
The reporter placed two orders for anti-depressants—Prozac and Elavil. A completed health survey appeared and the reporter submitted a credit card and Newsinferno.com,

Illegal Drug Sales on the Rise in US  -  May 23, 2008
A CNN investigative reporter visited a website and within 24 hours two bottles of the antidepressant drugs Prozac and Elavil arrived at his doorstep. InjuryBoard.com,

Widow describes losing her husband to overdose of drugs bought online  -  May 22, 2008
The reporter placed two orders for anti-depressants with the site: one for Prozac, the other for Elavil. A health survey on the site was already filled in. CNN International

Muscle Syndrome May Go Undetected  -  May 27, 2008
Antidepressants such as Elavil, which help some people, caused side effects for her -- dry mouth and a "dopey feeling" -- worse than the pain, RedOrbit,

PEOPLE'S PHARMACY Some drugs dull mental edge  -  May 17, 2008
In addition to medications for bladder control, many old-fashioned antidepressants such as amitriptyline (Elavil) also have anticholinergic activity. Houston Chronicle,

If Your Children Are Headed Off To Summer Camp, Could They Suffer ...  -  May 20, 2008
Other antidepressants, such as Elavil and Tophernil that are approved for children are used for anxiety in children as well because they are effective in Medical News Today (press release),

Elavil for Cystic Fibrosis?  -  Mar 31, 2008
But they could prevent lung inflammation and pseudomonas infection by giving the animals Elavil. Elavil is commonly used as an antidepressant. WebMD

Withering Glance: The spring of our discontent  -  Apr 4, 2008
For them there is Klonopin or Elavil. RN: Or every complex carbohydrate they can get their hands on. That's why they have become my default wintertime Minneapolis Star Tribune (subscription),

Experiments in mice sketch new treatment for cystic fibrosis  -  Mar 30, 2008
Amitriptyline -- commercialised under such names as Elavil, Endep and Vanatrip -- reduces levels in the lung of a fatty molecule called ceramide, AFP

Medication, not more surgery, may help back pain  -  Apr 5, 2008
These include Elavil, Lyrica and Neurontin. These medications, which can be very helpful in relieving the pain and numbness that you have in your legs, Munster Times,

Antidepressants Could Ease Cystic Fibrosis  -  Apr 2, 2008
Researchers from University of Duisburg-Essen in western Germany conducted a study showing that widely used amitriptyline drugs, such as Elavil, Endep, eMaxHealth.com,

Most older suicide victims not on antidepressants  -  Apr 15, 2008
The average suicide rates for male and female users of tricyclic antidepressants, such as Elavil and Asendin, were 153.3 and 68.8 suicides per 100000 people Reuters India,

Antidepressants raise risk of Type 2 diabetes  -  Mar 26, 2008
Brown said TCAs are among the "older" medications used to treat depression, under brand names such as Elavil and Aventyl. They were commonly used before Canada.com,

Orbus Signs Amytriptyline Licensing and Supply Agreements  -  Apr 2, 2008
It is a generic version of the Brand drug Elavil (r) that had Sales in Europe in 2006 of US$82 million. Orbus will manufacture the Amitriptyline at its Filing Services Canada (press release),

Health Highlights: March 31, 2008  -  Mar 31, 2008
In mice, the drug (sold under brand names such as Elavil, Endep and Vanatrip) reduced levels in the lung of a fatty molecule called ceramide, Forbes,

This is Your Brain on Drugs  -  Feb 29, 2008
Take your pick of 30 such antidepressants with soothing names and M&M-like colors -- Wellbutrin, Paxil, Celexa, BuSpar, Elavil, Vivactil, etc. Washington Post,

Multiple Chemical Sensitivity Beleaguered, Part 2: Pharmaceutical ...  -  Mar 2, 2008
Psychiatric drugs such as Zoloft, Prozac, Elavil, and other antidepressants are reported to harm an average of 60% of those who tried them and had no effect American Chronicle,

Smith's expanding $4 drug plan to Utah  -  Feb 13, 2008
For example, Delost said he charges $10 for a 100-day supply 10mg Amitriptyline, a generic form of the antidepressant Elavil. Under the Smith's plan, Salt Lake Tribune,

Brand Names/Synonyms:
Elavil is also known by the following brand names and/or synonymsAmimetilina; Anafranil; Apo-Amitriptyline; Apo-Imipramine; Apo-Trimip; Asendin; Aventyl; Elavil; Impril; Levate; MK 240; Norpramin; Novo-Doxepin; Novo-Tripramine; Novopramine; Novotriptyn; Pertofrane; Protriptyline; Protryptyline; Rhotrimine; Sinequan; Surmontil; Tofranil; Triadapin 5; Triptil; Vivactil

Drug Category:
Elavil is categorized under the following by the FDA: Antidepressants; Norepinephrine-Reuptake Inhibitors; ATC:N06AA11

Dosage Forms:
TABLET

Absorption:
Not Available

Interactions:
DRUG INTERACTIONS If Protriptyline is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Patient should check with doctor before combining Protriptyline with the following: Antidepressants that boost serotonin, including Paxil, Prozac, and Zoloft Antipsychotic medications such as Mellaril and chlopromazine Barbiturates such as Nembutal and Seconal Certain blood pressure medications such as guanethidine Cimetidine (Tagamet) Decongestants such as Sudafed Drugs that quell spasms, such as Donnatal and Levsin Epinephrine (EpiPen) Flecainide (Tambocor) Narcotic painkillers such as Percodan and Vicodin Norepinephrine Other antidepressants such as Elavil and Tofranil Propafenone (Rythmol) Quinidine Tramadol (Ultram) Tranquilizers and sleep aids such as Halcion, Valium, and Xanax Protriptyline must never be combined with monoamine inhibitors such as Nardil and Parnate.



Chemical IUPAC Name:
Not Available

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