Doxycycline

This page contains recent news articles, when available, and an overview of Doxycycline but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Doxycycline
(when available)

Pharmacology and use:
Doxycycline, a long-acting tetracycline derived from oxytetracycline, is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with COPD, and adult periodontitis. For the treatment of the following infections:Rocky mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by Rickettsiae, Chancroid caused by Haemophilus ducreyi, Uncomplicated gonorrhea caused by Neisseria gonorrhoeae, Respiratory tract infections caused by Mycoplasma pneumoniae or Streptococcus pneumoniae. Lymphogranuloma ve

Mechanism Of Action:
Doxycycline, like minocycline, is lipophilic and can pass through the lipid bilayer of bacteria. Doxycycline reversibly binds to the 30 S ribosomal subunits and possibly the 50S ribosomal subunit(s), blocking the binding of aminoacyl tRNA to the mRNA and inhibiting bacterial protein synthesis.

News Articles on Doxycycline

CDC Says Far Too Few Young Women Screened for Chlamydia  -  20 Apr 2009
A single dose of azithromycin or a week-long regimen of doxycycline taken twice daily, are the most commonly used treatments. “Because chlamydia is easily HealthNews

piggyBac transposition reprograms fibroblasts to induced ...  -  ‎Apr 15, 2009‎
Here we demonstrate successful and efficient reprogramming of murine and human embryonic fibroblasts using doxycycline-inducible transcription factors Nature.com (subscription)

Rapamycin weekly maintenance dosing and the potential efficacy of ...  -  ‎Apr 16, 2009‎
We also used a Tsc2-/- subcutaneous tumor model to evaluate other classes of drugs including sorafenib, atorvastatin, and doxycycline. 7thSpace Interactive (press release)

What Is Anthrax?  -  ‎Apr 2, 2009‎
Although Cipro is the only FDA approved antibiotic, others, such as doxycycline are effective. The American Lung Association notes that most suspicious Tampa Tribune

Mylan confirms four first-to-file challenges  -  ‎Mar 29, 2009‎
Doxycycline DR Capsules are the generic version of Galderma's adult rosacea treatment Oracea(R) Capsules, which had approximately $82 million in US sales News-Medical.net

Epididymitis and Orchitis  -  ‎Apr 1, 2009‎
Azithromycin (Zithromax), a single 1-g dose orally, may be substituted for doxycycline if treatment compliance is questionable. If epididymitis is thought AAFP News Now

Curcumin and Lung Cancer  -  ‎Apr 16, 2009‎
Curcumin's chemopreventive activity was tested in a transgenic mouse model of lung cancer that expresses the human Ki-rasG12C allele in a doxycycline (DOX) Natural Products Industry Insider

Subcutaneous Injection of Intranasal Canine Kennel Cough Vaccine  -  ‎Apr 17, 2009‎
The Infectious Disease department was consulted and switched her antibiotics from azithromycin to doxycycline for more effective Bordetella coverage. Psychosomatics (subscription)

Research Report on Chinese Chemical Pharmaceuticals Industry, 2009  -  ‎Apr 13, 2009‎
Antibiotics are the major export product in Chinese pharmaceuticals industry, including Penicillin-G, gentamicin, tetracycline tablets, doxycycline, PRLog.Org (press release)

A yeast-endonuclease-generated DNA break induces antigenic ...  -  ‎Apr 15, 2009‎
II -dox (doxycycline)). This increase was not observed for PS or –70. Error bars represent sem for 3 experiments. d, Representative flow cytometry plots for Nature.com (subscription)

Acne can persist in adulthood  -  ‎Apr 14, 2009‎
The next step up is oral antibiotics like doxycycline or minocycline. For severe acne, the doctor can inject cortisone into large, bothersome acne lesions. South Coast Today

Be very cautious with black or drawing salve  -  ‎Apr 15, 2009‎
...treatment from my doctor for almost two years: warm compresses, eyelid washing, flaxseed oil supplements, even a long-term course of doxycycline. Arizona Daily Star

MRSA Infections  -  ‎Apr 13, 2009‎
...against the specific strain of MRSA and may include vancomycin, linezolid, trimethoprim-sulfamethoxazole, doxycycline, tetracycline or clindamycin. MSN Health & Fitness

Avoid eating cut open fruits & vegetables  -  ‎Apr 16, 2009‎
There is no role of antibiotics unless it is a confirmed case of cholera where doxycycline is the drug of choice. Panna made out of unripe mango and The Day After

Waypoints: Medical Emergency Planning  -  ‎Apr 3, 2009‎
They include tetracycline (sometimes prescribed as Achromycin), doxycycline (sometimes prescribed as Vibramycin), ciprofloxacin (sometimes prescribed as Motor Boating Magazine

Chlamydia, a 'silent' sexual disease, spreads rapidly  -  ‎Mar 28, 2009‎
A single dose of azithromycin or a week of twice-daily doses of doxycycline are the most commonly used. Prevention: The surest way to avoid transmission is Tampabay.com

Dị dạng bạch mạch  -  ‎Apr 19, 2009‎
CaÌ?c thuôÌ?c gây xÆ¡ hoÌ?a được duÌ€ng bao gồm: Ethanol, Sodium tetradecyl sulphate, Bleomycine, OK - 432 vaÌ€ Doxycycline. Trong Ä‘oÌ? 3 thuôÌ?c đầu ngaÌ€y caÌ€ng Tuổi Trẻ

å?±æœºå…¬å…³ä¸­åª’体应该扮演什么角色  -  ‎Apr 2, 2009‎
...å·§å?ˆçš„æ˜¯ï¼Œå½“时一ç§?新型的抗炭疽病毒è?¯ç‰©â€œDoxycyclineâ€?刚被研究出æ?¥ï¼Œç›¸æ¯”昂贵的“Ciproflaxinâ€?,“Doxycyclineâ€?å?Œæ ·æœ‰æ•ˆè€Œä¸”价格低廉,于是顺利æˆ?章地,医生将这ç§?æ–°åž‹ 世界经理人

التهاب الجيوب الأنÙ?ية.. أسبابه وعلاجه  -  ‎Apr 15, 2009‎
مثل trimethoprim-sulfamethoxazole (وهو دواء مدمج يضم عقار السلÙ?ا)ØŒ Ùˆamoxicillin (وهو نوع من البنسلين) أو doxycycline (وهو نوع من التيتراسايكلين). عرب نت 5

Bệnh Lyme Gây Ra Ã?n Mạng  -  ‎Apr 6, 2009‎
Nếu được chữa trị sớm bằng thuốc trụ sinh như doxycycline, ciprofloxacine thì bệnh có thể lành hẳn nhưng cũng có những trư�ng hợp bệnh kéo dài và trở thành Take2Tango

专访å?Žäººå¥³ç§‘学家俞å?›è‹±  -  ‎Apr 15, 2009‎
...等利用è?¯ç‰©-病毒系统就能产生iPS细胞,å?³é€šè¿‡doxycyclineæ?¥æŽ§åˆ¶è½¬å½•å› å­?的表达,您认为是å?¦æœ‰å?¯èƒ½ä¸?用转录因å­?,å?ªç”¨åŒ–学物就能达到获得iPS细胞的目的? 生物通

Ipsen : Azzalure ® obtient l’autorisation de mise sur le marché en ...  -  ‎Mar 30, 2009‎
Oracea ® (doxycycline, rosacée), Clobex ® (proprionate de clobetasol, psoriasis), Tri-Luma ® (hydroquinone, trétinoïne, acétonide de fluocinolone, Business Wire (press release)

Thuốc Ä‘iá»?u trị trứng cá  -  ‎Apr 2, 2009‎
...nhân gây bệnh trong đó sá»± kết hợp giữa các thuốc dùng trong (Tetracycline, doxycycline, Erythromycin, các hormon ná»™i tiết tố) và các thuốc bôi ngoài. 24 giờ

Scott Miller and Company Premieres "A CALL TO ARMS 2009 EDITION ...  -  18 Mar 2009
...will be better protected by the anthrax vaccine, than by the immediate diagnosis and treatment with the generic methacillin antibiotic, doxycycline. PR Web (press release)

The dilemma of friends, family seeking advice  -  ‎Mar 16, 2009‎
She took a supply of the antibiotic doxycycline to protect herself. But a colleague alarmed her by saying some of the malaria strains were resistant to the Philadelphia Inquirer

Bladder Infections: One of the Scourges for Human Health  -  ‎Mar 16, 2009‎
As far as bladder infections are concerned, it has given rise to a variety of antibiotics like Doxycycline, Ciprofloxacin, Cephalosporins, Amoxicillin etc. Best Syndication

Tick trouble  -  ‎Mar 10, 2009‎
These types of antibiotics include doxycycline (for adults, children over 8 years of age, and women who are not pregnant), amoxicillin (for children and Jackson Sun

Nanotherapeutics Advances Two Clinical Programs-Investigational ...  -  ‎Mar 12, 2009‎
The company has begun recruiting patients for a phase IIa clinical study of NanoDOX(TM) 1% Doxycycline Monohydrate Hydrogel, a topical formulation of Small Times

Anti-malaria drug limited due to risks  -  ‎Mar 4, 2009‎
In cases where mefloquine and doxycycline are both effective in preventing malaria, doxycycline should be the "drug of choice," the Army surgeon general Stars and Stripes

Tetracyclines are equally effective for the treatment of acne vulgaris  -  ‎Feb 26, 2009‎
Although minocycline and doxycycline cost more, they require only once-daily dosing and may be better tolerated. There is no clear advantage to higher doses Journal of the American Academy of Physician Assistants

Avoid an Uncommon but Serious Side Effect of Acne Medication  -  ‎Mar 5, 2009‎
I also prefer derivatives such as doxycycline because they can be taken with food. This reduces the chance that the pill will lodge in the esophagus and Great Dad

Avidas(TM) Pharmaceuticals Introduces Avidoxy(TM) DK, Simplifying ...  -  ‎Mar 2, 2009‎
Avidoxy DK includes Avidoxy(TM) (Doxycycline Tablets), a broad spectrum oral antibiotic, in an easy-to-swallow film-coated caplet indicated as adjunctive eReleases (press release)

Free prescription antibiotics?  -  ‎Mar 2, 2009‎
The list of eight includes: Amoxicillin, Ampicillin, Cephalexin, Ciprofloxacin, Doxycycline, Erythromycin, Penicillin, Trimeth/Sulfa. ConnectAmarillo.com powered by KVII

SMIMER doctor to be reinstated  -  ‎Feb 28, 2009‎
Dudhwala was suspended for spreading wrong information in the city by stating that the stock of required medicines -- doxycycline -- to be distributed among Times of India

Emergence of Artemisinin-resistant Malaria Poses a Threat to ...  -  ‎Mar 17, 2009‎
Treatment involves antimalarials such as chloroquine, mefloquine, quinine, atovaquone-proguanil, doxycycline, artemisinin derivatives, to name a few. MediNEWS.Direct!

TV Recap: House – The Social Contract  -  ‎Mar 10, 2009‎
The doxycycline starts to work, but Foreman explains to Not-So-Nice that the brain damage is permanent. Rather than accept that, Not-So-Nice visits House’s Cinema Blend

Kenya moves to cap Trachoma  -  ‎Mar 5, 2009‎
Gesami said on Thursday that antibiotics can prevent long-term complications if used early in the infection, including Erythromycin and Doxycycline. Capital FM

2 face cruelty charges  -  ‎Feb 20, 2009‎
During a search in January, Futchko said, officers found cocaine, ketamine, marijuana, doxycycline and oxytetracycline along with several thousand Republican & Herald

Redefining Acne Vulgaris as a Chronic Disease  -  ‎Mar 4, 2009‎
Patients may also be given a low-dose (sub-antimicrobial) oral antibiotic, either doxycycline or minocycline, especially for those who have inflammatory Medscape

Virus-free Induction may Help the Effective Differentiation of ...  -  ‎Mar 13, 2009‎
Using the system, the researchers successfully delivered the doxycycline-inducible transcription factors into the murine and human embryonic fibroblasts. MediNEWS.Direct!

All your sex questions answered medically (Part II)  -  ‎Mar 2, 2009‎
Usual treatment is the superdrug Ceftriaxone given intramuscularly plus a few days of doxycycline tablets. See your doctor ASAP! Q. I have smelly yellowish Philippine Star

Sleepless in Botswana  -  ‎Mar 2, 2009‎
Volunteers are required to take malaria medications, such as Mefloquine and Doxycycline, which can have a sleep disrupting side effect. PR Newswire (press release)

The links between oral and systemic health  -  ‎Feb 26, 2009‎
7,8 The therapies included cleaning the tooth roots, antimicrobials (chlorhexidine 0.12% rinses), and doxycycline. These findings are of great clinical Clinical Advisor

AZZALURE® approved in the UK for Aesthetic Use  -  ‎Mar 12, 2009‎
Rozex®/MetroGel® 1% (metronidazole / rosacea), Oracea® (doxycycline / rosacea), Clobex® (clobetasol propionate / psoriasis), Tri-Luma® (hydroquinone, PipelineReview.com (press release)

*vwd/BUSINESS WIRE: Ipsen: AZZALURE^® Approved in the UK for ...  -  ‎Mar 11, 2009‎
Oracea^® (doxycycline / rosacea), Clobex^® (clobetasol propionate / psoriasis), Tri-Luma^® (hydroquinone, tretinoin, fluocinolone acetonide / pigmentary ddp-direkt.de (press release)

Hépatomégalie douloureuse multinodulaire et fièvre chez un homme ...  -  ‎Mar 13, 2009‎
En cas de rétinite, d’atteinte neurologique ou d’endocardite, l’association de doxycycline (200 mg/j) et de rifampicine (600 mg/j) pour quatre à six Hépato-Gastro (Abonnement)

Le paludisme d’importation en recrudescence  -  ‎Mar 6, 2009‎
Les Comores, Mayotte et l’Afrique du Sud sont classés en groupe 3 : on peut prescrire soit Malarone, soit Lariam, soit Doxycycline�, précise le Dr Lassalle. Clicanoo.com

Brand Names/Synonyms:
Doxycycline is also known by the following brand names and/or synonymsAlti-Doxycycline; Apo-Doxy; Atridox; DOXCYCLINE ANHYDROUS; Doryx; Doxy 100; Doxy-Caps; Doxy-Lemmon; Doxychel; Doxychel Hyclate; Doxycin; Doxycycline; Doxycycline Hyclate; Doxycycline Monohydrate; Doxylin; Doxytec; Doxytetracycline; GS-3065; Jenacyclin; Monodox; Novo-Doxylin; Nu-Doxycycline; Periostat; Supracyclin; Vibra-Tabs; Vibramycin

Drug Category:
Doxycycline is categorized under the following by the FDA: Antimalarials; Anti-bacterial Agents; Tetracyclines; ATC:A01AB22; ATC:J01AA02

Dosage Forms:
Tablet; Capsule; Gel; Liquid; Powder; Powder for Solution

Absorption:
completely absorbed after oral administration

Interactions:
-->Interactions for Doxycycline:

Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage.

Since bacteriostatic drugs may interfere with the bactericidal action of penicillin, it is advisable to avoid giving tetracyclines in conjunction with penicillin.

Absorption of tetracyclines is impaired by antacids containing aluminum, calcium, or magnesium, and iron-containing preparations.

Absorption of tetracycline is impaired by bismuth subsalicylate.

Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline.

The concurrent use of tetracycline and Penthrane (methoxyflurane) has been reported to result in fatal renal toxicity.

Concurrent use of tetracycline may render oral contraceptives less effective.

Drug/Laboratory Test Interactions

False elevations of urinary catecholamine levels may occur due to interference with the fluorescence test.





Chemical IUPAC Name:
2-(amino-hydroxy-methylidene)-4-dimethylamino-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione

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