Dextromethorphan

This page contains recent news articles, when available, and an overview of Dextromethorphan but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Dextromethorphan (when available)

Pharmacology and use:
Suppresses the cough reflex by a direct action on the cough center in the medulla of the brain. For treatment and relief of dry cough

Mechanism Of Action:
Dextromethorphan is an opioid-like drug that binds to and acts as antagonist to the NMDA glutamatergic receptor, it is an agonist to the opioid sigma 1 and sigma 2 receptors, it is also an alpha3/beta4 nicotinic receptor antagonist and targets the serotonin reuptake pump. Dextromethorphan is rapidly absorbed from the gastrointestinal tract, where it enters the bloodstream and crosses the blood-brain barrier. The first-pass through the hepatic portal vein results in some of the drug being metabolized into an active metabolite of dextromethorphan, dextrorphan, the 3-hydroxy derivative of dextromethorphan.

News Articles on Dextromethorphan

What is dextromethorphan?  -  Sep 9, 2008
Dextromethorphan can be found in more than 100 over-the-counter medicines. When used as directed DXM produces very few side effects and has a long history Hot Springs Star,

AVANIR Pharmaceuticals Wall Street Analyst Forum Presentation ...  -  Sep 10, 2008
Zenvia is a unique combination, it's the combination of dextromethorphan and quinidine, and you maybe familiar with dextromethorphan as it is available in Seeking Alpha,

Growing Teen Abuse of Snurf Pills  -  Sep 9, 2008
But the kids' symptoms -- and the effects reported by Snurf takers in online drug-user message boards -- point to dextromethorphan, the cough suppressant WebMD

NJ bill would limit sale of cold medicines  -  Sep 3, 2008
The proposal to ban cough and cold remedies containing DMX, or dextromethorphan, is being advanced by Democratic state Sen. Barbara Buono and Republican Sen Newsday,

Use of "Snurf Pill" puts Four Highschool Students’ life in danger!  -  Sep 9, 2008
DXM is dextromethorphan, a common ingredient in over the counter cold and cough remedies. When taken in large doses, DXM leads to a form of euphoria that is Newspost Online,

Advantages of DigiPol Automatic Polarimeters for UV Measurements ...  -  Sep 11, 2008
...'D' line but some materials need to be tested at other wavelengths even in the UV ( eg, Timolol Malleate @405 nm and Dextromethorphan HBr @325 nm, etc. Azom.com

Four Students Hospitalized After Taking "Snurf" Pills  -  Sep 10, 2008
But, reported symptoms by Snurf user’s points to dextromethorphan, a cough suppressant widely abused among teens for its sedative and hallucinogenic InjuryBoard.com,

Bill takes aim at cough medicine abuse  -  Sep 9, 2008
Barbara Buono (D-18th District) would prohibit the sale of medicines with the chemical dextromethorphan (DXM) to anyone under the age of 18. Greater Media Newspapers,

Senators target teen cough-drug abuse  -  Sep 3, 2008
..."The abuse of dextromethorphan is a growing problem in New Jersey and across the United States," Buono said. "Because the drugs are so readily available to The Star-Ledger - NJ.com,

M'sian students get high on RM1 cough pill  -  Sep 7, 2008
Nospan, also known by its generic name Dextromethorphan HBr, is a cough medicine derived from codeine and comes in tablet form. The pill is prescribed to AsiaOne,

MEDIA ADVISORY - Senator Barbara Buono To Hold Press Conference On ...  -  Aug 28, 2008
The bill would prohibit the sale of any product containing Dextromethorphan to anyone under the age of 18 years old. It targets recreational abusers of the Politicker,

US Neuropathic Pain Market Value Doubles to $5 Billion by 2018  -  Sep 11, 2008
...three glutamate / NMDA antagonists ketamine intranasal (Javelin), a dextromethorphan/quinidine combination (Avanir), and NP-1 (EpiCept/Epitome); MarketWatch

Medicine Cabinet Must-Haves  -  Sep 6, 2008
And for a cough syrup, look for a cough suppressant (Robitussin, dextromethorphan). For nasal congestion, you should keep some saline drops around (saline CBS News,

New Herbal 'Snurf' Drug Lands Teenagers in Hospital  -  Sep 11, 2008
...online by various Snurf users, and the symptoms of the four hospitalized teens, point to dextromethorphan (DXM), the active ingredient in Robitussin. Gay Wired,

Snurf Pills Abuse Growing in Teens  -  Sep 10, 2008
A concoction of dextromethorphan, also called DXM, it is a kind of synthetic morphine analog, usually seen in cough suppressants and some over-the-counter TheMedGuru,

Cops: Kid got 'herbal ecstasy' from uncle  -  Sep 10, 2008
According to several Web sites, Snurf typically consists of dextromethorphan, or DXM, a drug found in cough syrups that can act as a hallucinogen if taken Philadelphia Daily News,

Daily News' Quality Is Snarf-Worthy  -  Sep 9, 2008
It is often advertised as an herbal supplement, but generally consists of pure dextromethorphan, or DXM, a drug found in many cough syrups that can act as a PW-Philadelphia Weekly,

Regulation no substitute for common sense  -  Sep 7, 2008
The legislators are concerned about the potential for teenagers to use the substance — the full name is dextromethorphan — in order to get high. Scarlet Scuttlebutt,

NJ lawmakers should limit cold remedy sales  -  Sep 7, 2008
Last year in New Jersey, 205 teenagers were treated for taking overdoses of cold medication with suppressants made up of DMX or dextromethorphan. Cherry Hill Courier Post,

NJ Senators To Propose DXM Cough Medicine Ban  -  Sep 3, 2008
Ashley Angelat, 15, almost died from abusing an over-the-counter cough suppressant containing dextromethorphan, or DXM, an ingredient that if taken in large WCBS-TV New York,

Study Reinforces the Risk Associated with Cough and Cold ...  -  Sep 2, 2008
Evidence of recent administration of pseudoephedrine, antihistamine, dextromethorphan, and/or other cold-medication ingredients was detected in the Medi News Direct,

Honey Is a Natural Alternative to Harmful Cough Medicines  -  Aug 28, 2008
One group was given nothing, the second group was given a cough suppressant containing dextromethorphan DM, and the third group was given a spoonful of Natural News.com,

Joe Biden's pro-RIAA, pro-FBI tech voting record  -  Aug 23, 2008
Another prohibits selling a product containing dextromethorphan -- including Robitussin, Sucrets, Dayquil, and Vicks -- "to an individual under the age of CNET News,

What's In Your Medicine Cabinet?  -  Aug 22, 2008
Many don't know that overdosing on Coricidin®, which contains the chemical dextromethorphan (or DXM) can cause hallucinations and death. TransWorldNews (press release),

Teen expo promotes healthy choices  -  Aug 21, 2008
One recent trend addressed at the expo was the abuse of products containing the cough suppressant Dextromethorphan. Base officials recently implemented a U.S. Marine Corps Bases Japan,

Opioid Painkillers Sometimes Make Pain Worse, According to ...  -  Aug 21, 2008
Additional medications can be used to help minimize the need for opioids, such as COX-2 inhibitors, dextromethorphan, and others. >> Long-acting opioids are PR-CANADA.net (press release),

Warning--More Local Teens Abusing Common Household Medications  -  Aug 21, 2008
The most commonly abused household drug, Garcia says, is dextromethorphan, which is the active ingredient in Robitussin and Coricidin Cough and Cold Tablets 1200 WOAI,

FDA Law Enforcers Protect Consumers' Health Inside the Office of ...  -  Aug 19, 2008
Dextromethorphan (DXM), a cough suppressant, was sold over the Internet through their Web site. This case started in 2005 when five young people died after Food Consumer,

CITY BLOGS  -  Aug 17, 2008
In fact, in 1997, the American Academy of Pediatrics even warned that codeine and dextromethorphan (DM) -- two of the four most common ingredients in cough The Post,

Drugs We Don’t Feel Like Trying: Snurf  -  Sep 9, 2008
Snurf would seem to be, then, mostly unadulterated dextromethorphan, also known as “DXM,�? which you and I would recognize as a base ingredient in cough Philebrity.com,

Zelfzorggeneesmiddelen met domperidon en/of dextromethorphan niet ...  -  Sep 3, 2008
Het College ter Beoordeling van Geneesmiddelen (CBG) heeft besloten domperidon en dextromethorfan bevattende geneesmiddelen voortaan in de categorie Medical facts,

Zelfzorggeneesmiddelen met domperidon en/of dextromethorphan  -  Aug 29, 2008
Het College ter beoordeling van Geneesmiddelen heeft in juli besloten dat geneesmiddelen die domperidon en/of dextromethorphan bevatten uitsluitend nog in apothekersnieuws.nl,

新州議員擬�??案�?售咳藥予少年  -  Sep 4, 2008
...肯因(Tom Kean)�??出的法案，�?求�?止出售�?�有DXM(dextromethorphan 香港新浪網,

Honig hilft dem Hals  -  Aug 31, 2008
Medical Principles and Practice 2006; 15: 456-458 Paul IM et al: Effect of honey, dextromethorphan, and no treatment on nocturnal cough und sleep quality Deutschlandradio,

Domowe leczenie nocnego kaszlu u dzieci  -  Aug 29, 2008
Graudins A., Fern RP: Acute dystonia in a child associated with therapeutic ingestion of a dextromethorphan containing cough and cold syrup. J. Toxicol. Medycyna Praktyczna,

Paracetamol außerhalb der Apotheke  -  Aug 19, 2008
Empfohlen wurde anstelle von Diphenhydramin, Dextromethorphan, Guaifenesin, Pseudoephedrin und Oxymetazolin die Anwendung von Paracetamol und Ibuprofen apotheke-adhoc,

Parents: be aware of cough medication abuse  -  07 Aug 2008
When used correctly, dextromethorphan cough medications have a 50-year history of being safe and effective. But when abused, dextromethorphan can produce Melrose Free Press,

AVANIR Reports Third Quarter Fiscal 2008 Financial Results  -  07 Aug 2008
About Zenvia Zenvia is a combination of two well-characterized compounds: the therapeutically active ingredient dextromethorphan and the enzyme inhibitor WELT ONLINE,

CHPA and CADCA Commend Senators Biden and Grassley on National ...  -  Jul 17, 2008
When used correctly, dextromethorphan-containing medicines have a 50-year history of being safe and effective. But when abused in extreme excess, FOXBusiness

Honey Better Than Cough Medicine For Soothing Kids' Cough Symptoms  -  Jul 20, 2008
The participants were given either a small dose of buckwheat honey, honey-flavored dextromethorphan or no treatment at all a half-hour before bed. Natural News.com,

Public Hearing On Proposed Cough Syrup Legislation  -  Jul 10, 2008
...scheduled a public hearing on a proposed local law that would ban the sale in Westchester of cough syrup containing Dextromethorphan (DXM) to minors. Westchester.com,

MDMA, Ecstasy- Dangerous Club Drugs  -  Jul 28, 2008
Fraudulent MDMA tablets frequently contain combinations of ephedrine, dextromethorphan, and caffeine or newer piperazine compounds. TransWorldNews (press release),

Family health ... take charge! Virus for common cold never takes ...  -  Jul 27, 2008
Cough suppressants that contain dextromethorphan (labeled DM or Tuss) can cause hallucinations, poor judgment and other serious problems if taken in high Memphis Commercial Appeal,

Stabbing victim may have been instigator  -  Jul 27, 2008
One, dextromethorphan, can be a hallucinogen in large doses. His wife said last week that she didn't know that. The grand jury likely didn't see evidence of Columbus Dispatch,

Cough Syrup Abuse  -  Jul 15, 2008
More than 125 commercial cough remedies in the United States contain the synthetic drug dextromethorphan (DXM). This drug is similar to morphine, TransWorldNews (press release),

US Sen. Grassley: Biden, Grassley Mark the Drug Enforcement ...  -  Jul 8, 2008
Biden and Grassley introduced legislation (S.2274) to curb the rising abuse of the active ingredient, Dextromethorphan (DXM), found in many cough and cold IowaPolitics.com (press release),

Westchester board OKs building purchase  -  Jul 9, 2008
Also last night, the board set a public hearing on a proposedÂ law that would ban the sale in of cough syrup containing Dextromethorphan (DXM) to minors. Politics on the Hudson,

Wundertüten in Pharmazie und Alltag  -  Jul 8, 2008
Auch in Dextromethorphan-HBr-haltigen Lutschpastillen zur Hustenstillung findet man das natürliche β-CD. Hier dient es ebenfalls als Stabilisator und pharmazeutische-zeitung.de,

Drogenproblem Medikamentenschrank  -  Jul 9, 2008
Der Zürcher Apothekerverband setzte beispielsweise Verkaufsrichtlinien für Hustenmittel und andere Medikamente fest, die Dextromethorphan enthalten. NZZ Online,

L�?i khuyên đi�?u trị cảm và cúm  -  Jul 27, 2008
Thêm vào đó, trong dòng những sản phẩm thuốc chống ho dạng viên và dạng dung dịch ngậm có chứa thành phần dextromethorphan (DXM), khi sử dụng quá li�?u loại Dân Trí,

Sales spikes, overdoses prompt drug restrictions  -  Jun 30, 2008
For several months last year, Cooper and Pfc. Stephen Wanser say they abused Coricidin Cough and Cold, which contains dextromethorphan, or DXM. Stars and Stripes,

Walgreen spent $300000 lobbying in first quarter  -  Jun 25, 2008
...of drugs and medical devices, lead standards, restrictions on sales of the cough suppressant Dextromethorphan, organized retail crime and other issues. CNNMoney.com

AVANIR Announces Grant of New Zenvia Patent  -  Jun 19, 2008
EPO patent number 1.539.166 titled "Pharmaceutical Compositions Comprising Dextromethorphan and Quinidine for the Treatment of Neurological Disorders" will RedOrbit,

S'town pharmacies among those AG Cuomo says sold expired food  -  Jun 20, 2008
By Arlene Gross The state attorney general's office has issued a statement stating its plans to sue CVS and Rite Aid pharmacies for selling expired products Times of Smithtown,

Cough suppressant may ease fibromyalgia pain  -  Jun 4, 2008
Researchers found that the cough suppressant, dextromethorphan, temporarily diminished pain perception in both fibromyalgia patients and healthy adults. PakTribune.com,

Divi`s Labs: In good health  -  Jun 10, 2008
Divi's is possibly one of the top three global generic suppliers of Naproxen (arthritis), Diltiazem (anti-hypertensive) and Dextromethorphan (medication for Business Standard,

Walgreens Sued Over Infant Death Due to Cold Medicine  -  Jun 6, 2008
..."This may be the first case against manufacturers of infant cold and cough medicines with dextromethorphan," said Ralph Davis, attorney for the plaintiff. Natural News.com,

Cold medicines pulled from shelves on Okinawa bases  -  Jun 6, 2008
Greeting them instead are notices that all over-the-counter medications containing DXM, or dextromethorphan, have been removed for now. Stars and Stripes,

Divi's continues its pursuit of leadership in generic APIs  -  Jun 29, 2008
It has attained market leadership in various products like dextromethorphan, phenyleffrine, nabumetone and lopamidol; these products alone contribute 30% to Sify,

Instructions on Internet: narcotics from cough mixture by means of ...  -  Jun 5, 2008
From Resilar one can extract dextromethorphan (DXM), which, especially in high doses, is an extremely potent and dangerous narcotic. Helsingin Sanomat,

Stressed nurse took cocktail of sedatives  -  Jun 13, 2008
A toxicology report found the mother-of-two had taken drugs including zopicione, chlorpromazine, promethazine, mirtazaphine, dextromethorphan, diazepam and East Anglian Daily Times,

OTC Firm Used Wrong Identity Test, Warning Letter Follows  -  Jun 13, 2008
The company used the USP <197k> infrared spectrophotometric identity test for incoming APIs dextromethorphan tannate, pseudoephedrine tannate and FDA news (subscription),

Helena man facing life in prison  -  Jun 10, 2008
The pills contain Dextromethorphan, which when taken in high doses can produce feelings of euphoria and hallucinations that some seek to get high, Helena Independent Record,

Say No to Cold Medicine, Yes to Honey  -  Jun 5, 2008
...honey-flavored dextromethorphan (a common ingredient in many overthe-counter cold medications) or no treatment at all 30 minutes prior to bedtime. RedOrbit,

AVNR: Granted New European Patent for Zenvia(TM)  -  Jun 19, 2008
AVANIR a new patent, extending the period of commercial exclusivity for its lead drug candidate Zenvia(TM) (dextromethorphan/quinidine) into 2023. Trading Markets (press release),

Brand Names/Synonyms:
Dextromethorphan is also known by the following brand names and/or synonyms&Laquo;Delta&Raquo;-Methorphan; Antussan; Ba 2666; Balminil Dm; Balminil Dm Children; Benylin Adult Formula Cough Suppressant; Benylin Dm; Benylin Dm 12 Hour; Benylin Dm for Children; Benylin Dm for Children 12 Hour; Benylin Pediatric Cough Suppressant; Calmylin #1; Canfodion; Cosylan; Cough-X; Creo-Terpin; D-Methorphan; D-Methorphan Hydrobromide; Dea No. 9210; Delsym; Delsym Cough Formula; Delta-Methorphan; Demorphan; Demorphan Hydrobromide; Demorphine; Destrometerfano [Dcit]; Dextromethorfan; Dextromethorfan [Czech]; Dextromethorphan; Dextromethorphan Bromhydrate; Dextromethorphan Bromide; Dextromethorphan [Ban:Inn]; Dextrometorfano [Inn-Spanish]; Dextrometorphan; Dextromorphan; Dexyromethorphan; Diabe-Tuss Dm Syrup; Dormetan; Dormethan; Hihustan M.; Hold Dm; Koffex Dm; L-Methorphan; Levomethorphan; Levomethorphan [Ban:Dcf:Inn]; Levomethorphane [Inn-French]; Levomethorphanum [Inn-Latin]; Levometorfano [Inn-Spanish]; Medicon; Methorate Hydrobromide; Methorphan; Metrorat; Novahistex Dm; Novahistine Dm; Pertussin Cs Children's Strength; Pertussin Dm Extra Strength; Racemethorphan [As D-Form]; Robitussin Maximum Strength Cough Suppressant; Robitussin Pediatric; Robitussin Pediatric Cough Suppressant; Romilar; Sucrets 4 Hour Cough Suppressant; Triaminic Dm Long Lasting for Children; Trocal; Tusilan; Tussade; Vicks 44 Cough Relief

Drug Category:
Dextromethorphan is categorized under the following by the FDA: Antitussives; Analgesics; Antitussives; ATC:R05DA09

Dosage Forms:
SYRUP

Absorption:
Not Available

Interactions:
Not Available

Chemical IUPAC Name:
Not Available

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