Desogestrel

This page contains recent news articles, when available, and an overview of Desogestrel but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Desogestrel
(when available)

Pharmacology and use:
Desogestrel is used as a female contraceptive. Desogestrel is a progestin or a synthetic form of the naturally occurring female sex hormone, progesterone. In a woman's normal menstrual cycle, an egg matures and is released from the ovaries (ovulation). The ovary then produces progesterone, preventing the release of further eggs and priming the lining of the womb for a possible pregnancy. If pregnancy occurs, progesterone levels in the body remain high, maintaining the womb lining. If pregnancy does not occur, progesterone levels in the body fall, resulting in a menstrual period. Desogestrel tricks the body processes into thinking that ovulation has already occurred, by maintaining high levels of the synthetic progesterone. This prevents the release of eggs from the ovaries. For the prevention of pregnancy in women who elect to use this product as a method of contraception.

Mechanism Of Action:
Binds to the progesterone and estrogen receptors. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Once bound to the receptor, progestins like desogestrel will slow the frequency of release of gonadotropin releasing hormone (GnRH) from the hypothalamus and blunt the pre-ovulatory LH (luteinizing hormone) surge.

News Articles on Desogestrel

Oral Contraceptives Linked to Higher Lupus Risk  -  ‎Apr 6, 2009‎
Third-generation versions combined ethinyl estradiol with either gestodene, desogestrel, or norgestimate. Through an average follow-up of eight years, MedPage Today

Hirsutism- Everything You Wanted To Know  -  ‎Apr 13, 2009‎
These compounds tend to have stronger androgenic effects, while those with ethynodiol diacetate, norgestimate, and desogestrel are less androgenic. 마인드스포츠올림피아드

Oral contraceptive use may increase Lupus risk  -  ‎Apr 9, 2009‎
Use of third-generation contraceptives that combined ethinyl estradiol with either gestodene, desogestrel, or norgestimate was not associated with increased TheMedGuru

In tema di nuovi progestinici  -  ‎Apr 9, 2009‎
I gonani si distinguono in molecole di 2° generazione, quali il levonorgestrel (LNG) e molecole di 3° generazione (desogestrel, gestodene, norgestimate) I Fondazione Serono

Peuteren-blog Onderwerpen van Peuteren.nl  -  ‎Apr 15, 2009‎
...(op basis van D-norgestrel en levonorgestrel) een hoger risico lopen dan pilgebruiksters van de derde generatie (op basis van desogestrel of gestodeen). Peuteren.nl

La píldora masculina podría estar en los genes  -  ‎Apr 2, 2009‎
El laboratorio Organon probó en 2000 una hormona sintética usada en la píldora, desogestrel. Aunque los ensayos parecían prometedores, no ha vuelto a haber Público

Parcerias público-privadas viabilizam produção nacional de 24 ...  -  ‎Apr 1, 2009‎
Serão três anticoncepcionais: a ciproterona em associação com o etinilestradiol, o desogestrel eo etinilestradiol. O Laboratório Químico Farmacêutico do Agência de Notícias da Aids

NuvaRing Side Effects  -  18 Mar 2009
It contains a combination of the hormones estrogen and etonogestrel which is a synthetic form of the progestin desogestrel. NuvaRing uses a different form Reporte 15 Minutos

Injectable Birth Control Causes Significant Weight Gain And ...  -  ‎Mar 4, 2009‎
The study followed 703 women in two age categories, 16- to 24-years-old, and 25- to 33-years-old, using DMPA, oral (desogestrel) or nonhormonal (bilateral Science Daily (press release)

The risks of contraceptive pills  -  Jan 21, 2009
Your risk may be slightly higher if you take a pill containing the hormones desogestrel or gestodene. Women who aren't on the pill have a 1 in 20000 chance guardian.co.uk,

What treatments work for painful periods?  -  Jan 21, 2009
Primary dysmenorrhea treatment with a desogestrel-containing low-dose oral contraceptive. Contraception. 2002; 66: 393-399. Davis AR, Westhoff C, guardian.co.uk,

Hirsutism- Everything You Wanted To Know  -  Dec 11, 2008
...chemical compounds tend to have stronger androgenic effects, while those with ethynodiol diacetate, norgestimate, and desogestrel are less androgenic. Meadow Free Press,

Gefährlicher Mythos Cola schützt nicht vor Schwangerschaft  -  Dec 18, 2008
Hormonelle VerhütungMinipille mit Desogestrel Die Minipille enthält lediglich ein Gestagen, das den Eisprung verhindert und das Eindringen der Spermien in Bild.de,

23 % de los embarazos en adolescentes no son deseados  -  Nov 18, 2008
Desogestrel y etonogestrel son los nombres de sus componentes, y tienen como función principal endurecer el moco cervical para que no pueda pasar el esperma Vanguardia (México),

Contraccettivi di terza generazione associati ad aumento del ...  -  Nov 3, 2008
La ricerca mette in evidenza che farmaci il cui principio attivo è dato da sostanze quali desogestrel e gestodene creano una condizione di infiammazione cybermed.it,

Lần đầu tiên triển khai tại Khánh Hòa  -  Oct 8, 2008
...chứa etonogestrel (ENG), một chất chuyển hóa có hoạt tính sinh h�c của desogestrel, một progestagen được sử dụng rộng rãi trong thuốc viên ngừa thai. Khanh Hoa,

Redaktionsservice Verhütung: Stillen? Aber sicher! WHO/UNICEF ...  -  Sep 30, 2008
Das darin enthaltene Gestagen Desogestrel hat keinerlei Einfluss auf die Milchmenge und die in der Muttermilch enthaltenen Nährstoffe. news aktuell (Pressemitteilung),

NuvaRing Lawsuits Consolidated  -  Aug 27, 2008
Etonogestral is an active metabolite of desogestrel, a form of the hormone progestin. In 2003 the New England Journal of Medicine published two studies that Newsinferno.com,

Carmichael mom, 22, dies; family questions safety of birth control  -  Sep 1, 2008
Last year, the consumer group Public Citizen asked the Food and Drug Administration to ban oral contraceptives containing desogestrel, a variant of one of Sacramento Bee,

Prescribing Oral Contraceptives to Acne Patients  -  Jul 31, 2008
Newer combinations containing drospirenone, desogestrel, or norgestimate are less androgenic and, as a result, may be more beneficial for the treatment of Medscape (subscription)

Cele mai frecvente intrebari despre anticonceptionale  -  Jul 20, 2008
Anumite progestative, cum ar fi etinodiol diacetat, desogestrel si nerogestimat sunt consdierate ca avnd un efect benefic asupra pielii. Kidz,

Counting the pills  -  Jun 23, 2008
GSK has a low dose pill, Elogen (desogestrel and ethinylestradiol), and Zerogen (progesterone only pill). "Mankind has Unwanted-72 ie, levonorgestril 1.5 mg Express Pharma,

Should the Birth Control Patch Be Pulled?  -  May 9, 2008
After all, Wolfe petitioned the FDA last year concerning birth control pills that contain a new formulation of estrogen called desogestrel, that, U.S. News & World Report,

Newer oral contraceptives alter inflammatory status of young women  -  Apr 21, 2008
Third-generation agents containing desogestrel or gestodene were introduced to reduce the adverse effects of oral contraceptives, especially cardiovascular Medicexchange,

THE LAW OFFICES OF JAMES SOKOLOVE WARNS CONSUMERS OF BIRTH CONTROL ...  -  Apr 10, 2008
Three independent studies published in 1995 showed that third-generation oral contraceptives, which contain the progestin desogestrel, carry nearly twice openPR (press release),

Woman warns others not to use NuvaRing  -  Apr 6, 2008
In February 2007 it petitioned the US Food and Drug Administration to ban oral contraceptives that contain desogestrel. It's a synthetic compound the group News-Leader.com,

Hair today gone tomorrow  -  Jan 12, 2008
The best (and, therefore, those to look out for) are drospirenone and cyproterone acetate, desogestrel and norgestimate. Less favourable are levonorgestrel, Times Online,

Undermining Parents  -  Nov 11, 2007
Earlier this year the group petitioned the Food and Drug Administration to ban several popular low-dose oral contraceptives containing desogestrel, Zenit News Agency,

American Life League Says Birth Control Pill Can Kill; Suggests ...  -  14 Oct 2007
The new third generation of birth control pills, ones containing desogestrel, can double the already increased risk of blood clots. Associated Content,

Birth Control Pills’ Diabetes Risk, Safety for Sickle Cell ...  -  May 3, 2007
Health Behavior News ServiceWomen who took a pill with desogestrel as the progestin had better blood glucose levels than those who took other kinds of pills, but the effect was

'The pill': long-lived standard  -  Apr 3, 2007
NorthJersey.com,...(Labels of birth-control pills containing desogestrel already list that increased risk in fine-print.) "While the use of any type of combined oral

Oral Contraceptives Tied to Allergy Risk in Children  -  Dec 29, 2006
Medscape (subscription)The team found that, compared to children whose mothers had not used OCPs, maternal use of desogestrel, gestodene or cyproterone acetate each combined with

Simvastatin May Help Ameliorate Polycystic Ovary Syndrome  -  Nov 27, 2006
Medscape (subscription)24 women were assigned to 12 weeks of statin plus OCP (20 mg daily of simvastatin plus 20 μg of ethinyl estradiol and 150 μg of desogestrel) then 12 weeks

'Measurable and statistically significant' connection confirmed  Oct 23, 2006
...desogestrel and norgestimate) have been introduced, the hormone-free interval has been shortened, and new delivery systems have become available.". ... -WorldNetDaily, What women need to know (About reproductive health)  Aug 21, 2006
Organon recently introduced low-dosed oral pill Desogestrel 150 mg/Ethinylestradiol 30 g. It harmoniously works with the anatomy of the modern woman. ... -Manila Standard Today

Brand Names/Synonyms:
Desogestrel is also known by the following brand names and/or synonymsCerazette; Cyclessa; DESOGESTREL; Desogen; Desogestrel; Desogestrel [Usan:Ban:Inn]; Desogestrelum [Inn-Latin]; HSDB 3593; Kariva; Mircette; ORG 2969; Org-2969, Cerazette; Ortho-Cept

Drug Category:
Desogestrel is categorized under the following by the FDA: Contraceptives, Oral, Synthetic; ATC:G03AC09

Dosage Forms:
TABLET

Absorption:
Following oral administration, the relative bioavailability of desogestrel compared to a solution, as measured by serum levels of etonogestrel, is approximately 100%.

Interactions:
-->Interactions for Desogestrel:

Reduced efficacy and increased incidence of breakthrough bleeding and menstrual irregularities have been associated with concomitant use of rifampin. A similar association, though less marked, has been suggested with barbiturates, phenyl-butazone, phenytoin sodium, carbamazepine and possibly with griseofulvin, ampicillin, and tetracyclines (72).

 
 




Chemical IUPAC Name:
13-ethyl-17-ethynyl-11-methylidene-1,2,3,6,7,8,9,10,12,13,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-ol

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