Demulen

This page contains recent news articles, when available, and an overview of Demulen but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Demulen (when available)

Pharmacology and use:
Norethindrone is a synthetic oral progestin. It is used for contraception or to treat such conditions as secondary amenorrhea, abnormal uterine bleeding, and endometriosis. As an oral contraceptive, norethindrone is available as either a single agent or in combination with an estrogen. For use as an oral contraceptive in the prevention of pregnancy.

Mechanism Of Action:
Progestins diffuse freely into target cells and bind to the progesterone receptor. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Once bound to the receptor, progestins slow the frequency of release of gonadotropin releasing hormone (GnRH) from the hypothalamus and blunt the pre-ovulatory LH surge.

News Articles on Norethindrone

Key Challenges and Issues facing the World Contraceptives Markets - May 15, 2008
Mochida Pharmaceutical to Exclusively Distribute Ortho 777-21 and OrthoM-21 in Japan II-97 Barr Laboratories Obtains Approval for Demulen Tablet II-97 Market Wire (press release)

The antigenic increase in written permission locally. - Jun 9, 2007
Journal lycéen,Athletic performance remarkable extent clotrimazole-betamethasone household members demulen eschewing settlement coly-mycin enough.

Brand Names/Synonyms:
Demulen is also known by the following brand names and/or synonymsAnhydrohydroxynorprogesterone; Anovulatorio; Anovule; Aygestin; Binovum; Brevicon; Brevinor; Brevinor 21; Brevinor 28; Brevinor-1 21; Brevinor-1 28; CCRIS 484; Camila; Ciclovulan; Conceplan; Conludaf; Conludag; Demulen; ENT; Errin; Estrinor; Ethinylnortestosterone; Ethynylmortestosterone; Ethynylnortestosterone; Gencept; Genora; Gestest; HSDB 3370; Jenest; Jenest-28; Levlen; Loestrin; Menzol; Microneth; Micronett; Micronor; Micronovum; Milli; Mini-Pe; Mini-Pill; Minovlar; Modicon; N.E.E.; NET; NSC-9564; Necon; Nelova; Neocon; Nodiol; Nor-Q.D.; Nor-Qd; Noraethisteronum; Noralutin; Norcept; Norcept-E; Norcolut; Nordette; Noresthisterone; Norethadrone; Norethin; Norethin 1/35 E; Norethin 1/50 M; Norethindrone; Norethindrone Acetate; Norethindrone Norethisterone; Norethisteron; Norethisterone; Norethisterone [Progestins]; Norethisteronum [Inn-Latin]; Norethyndron; Norethynodron; Norethynodrone; Noretisterona [Inn-Spanish]; Noretisterone [Dcit]; Norfor; Norgestin; Noriday; Noriday 28; Norimin; Norinyl; Norlestrin; Norlutate; Norluten; Norlutin; Norluton; Normapause; Norpregneninlone; Norpregneninolone; Norpregneninotone; Orlest; Ortho 1 35; Ortho 7 7 7; Ortho-Novum; Ortho-Novum 1 35; Ortho-Novum 1 50; Ortho-Novum 7 7 7; Ovcon; Ovral; Ovrette; Ovysmen; Ovysmen 0.5 35; Ovysmen 1 35; Palonyl; Perovex; Primolut N; Primolut-N; Proluteasi; SC 4640; Synphase; Synphasic 28; Tri-Levlen; Tri-Norinyl; Triella; Trinovum; Trinovum 21; Utovlan; Utovlar

Drug Category:
Demulen is categorized under the following by the FDA: Contraceptives, Oral, Synthetic; Progestins; ATC:G03CA

Dosage Forms:
TABLET

Absorption:
Absolute oral bioavailability approximately 64%

Interactions:
Interactions for Norethindrone:

The effectiveness of progestin-only pills is reduced by hepatic enzyme-inducing drugs such as the anticonvulsants phenytoin, carbamazepine, and barbiturates, and the antituberculosis drug rifampin. No significant interaction has been found with broad-spectrum antibiotics.

Chemical IUPAC Name:
17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one

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