Clindesse

This page contains recent news articles, when available, and an overview of Clindesse but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Clindesse (when available)

Pharmacology and use:
Clindamycin is an antibiotic, similar to and a derivative of lincomycin. Clindamycin can be used in topical or systemic treatment. It is effective as an anti-anaerobic antibiotic and antiprotozoal. For the treatment of serious infections caused by susceptible anaerobic bacteria (anaerobes, streptococci, pneumococci, and staphylococci)

Mechanism Of Action:
Systemic/Vaginal-Clindamycin inhibits protein synthesis of bacteria by binding to the 50 S ribosomal subunits of the bacteria. Topical-Clindamycin reduces free fatty acid concentrations on the skin and to suppress the growth of Propionibacterium acnes (Corynebacterium acnes) , an anaerobe found in sebaceous glands and follicles.

News Articles on Clindamycin

BUYINS.NET: BJGP, GETI, ITWO, PANL, PCLN, PPCO Have Also Been ...  -  Apr 17, 2008
The company's developing products include Ferriprox for iron overload; Flashtab Ondansetron for nausea and vomiting; Clindesse for bacterial vaginosis; Manufacturing Business Technology,

KV Pharmaceutical Reports Record Revenues for Fiscal 2008 Third ...  -  Feb 28, 2008
Year to date, revenues for the products were $27.8 million and $20.4 million for Clindesse(R) and Gynazole-1(R), respectively, combining for an 18.3% FOXBusiness

KV Pharmaceutical Company Completes Unaudited Fiscal 2007 Results ...  -  Feb 15, 2008
Clindesse(R), now holds 27.9% of the intra-vaginal bacterial vaginosis market and the product contributed $31.8 million in net revenues during fiscal 2007. PR Newswire (press release),

KV buys premature birth treatment drug for $82 million  -  Jan 22, 2008
These include PrimaCare prenatal vitamins, Clindesse vaginal anti-infective products; and Evamist, the first FDA-approved transdermal spray for the St. Louis Post-Dispatch,

KV Pharmaceutical Company Announces Acquisition of Rights to ...  -  Jan 22, 2008
Leading one-dose prescription vaginal anti-infective products, including Clindesse(R), the fastest growing branded intra-vaginal prescription product Earthtimes,

Beijing Med-Pharm Hopes To Grow Quickly Through Acquisitions  -  Aug 23, 2007
Clindesse. Clindesse, or clindamycin phosphate vaginal cream, is indicated for the treatment of bacterial vaginosis in non-pregnant women. Seeking Alpha,

KV Pharmaceutical Company Announces Licensing Agreement in China ...  -  Jul 10, 2007
CNNMoney.comUnder the terms of the agreement, Beijing Med-Pharm has agreed to complete late-stage clinical development and registration of Clindesse(TM) with the SFDA

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FDA Sends Letter to KV Pharmaceutical About Clindesse E-Mail/Alert  -  May 22, 2007
PharmaLive.com (press release),ROCKVILLE, Md., May 22, 2007-The FDA today posted on its website a letter sent to KV Pharmaceutical Company about an e-Pharm/alert email for Clindesse

KV Pharmaceutical Company Reports Preliminary Record Revenues for ...  Nov 6, 2006
During the second quarter, Ther-Rx's anti-infective product Clindesse(TM) continued to show growth. Clindesse(TM) remains the fastest ... -MSN Money KV Pharmaceutical Company Reports Fiscal 2007 First Quarter ...  Aug 8, 2006
For the first quarter of fiscal 2007, the Company's anti-infective products, Gynazole-1® and Clindesse(TM), reported net sales of $7.3 million and $5.3 million ... -Yahoo! News

KV Pharmaceutical Reports Record Revenues for Fiscal 2006 Third ... Feb 7, 2006
OPERATING HIGHLIGHTS: Ther-Rx Corporation Revenues Up 60% -- Clindesse(TM) Continues To Reach New Highs in New Prescriptions and Contributes $15.1 Million Year ... - PR Newswire,

Hungary Richter grants exclusive marketing rights to KV ...  Feb 14, 2006
...been a terrific partner as demonstrated by the international licensing of our two NDA approved anti-infective products, Gynazole-1® and more recently Clindesse ... - Portfolio.hu,

KV Pharmaceutical Reports Record Revenues for Fiscal 2006 Third ...  Feb 7, 2006
OPERATING HIGHLIGHTS: Ther-Rx Corporation Revenues Up 60% -- Clindesse(TM) Continues To Reach New Highs in New Prescriptions and Contributes $15.1 Million Year ... - PR Newswire

Brand Names/Synonyms:
Clindesse is also known by the following brand names and/or synonymsChlolincocin; Cleocin; Cleocin Hcl; Cleocin Pediatric; Cleocin Phosphate; Cleocin T; Cleocin T Gel; Cleocin T Lotion; Cleocin T Topical Solution; Clinda-Derm; Clindagel; Clindamicina [Inn-Spanish]; Clindamycin; Clindamycin Hcl; Clindamycin Hydrochloride; Clindamycin Phosphate; Clindamycin [Usan:Ban:Inn]; Clindamycine [French]; Clindamycine [Inn-French]; Clindamycinum [Inn-Latin]; Clindesse; Clindets; Clinimycin; DRG-0011; Dalacin; Dalacin C; Dalacin C Flavored Granules; Dalacin C Phosphate; Dalacin T Topical Solution; Evoclin; HSDB 3037; Sobelin

Drug Category:
Clindesse is categorized under the following by the FDA: Anti-bacterial Agents; Lincomycins; ATC:D10AF01; ATC:G01AA10; ATC:J01FF01

Dosage Forms:
capsules; Intramuscular solution; Intravenousparenteral solution; Topical Solution; Topical Lotion; Topical Gel; Vaginal Cream; Vaginal Ovules

Absorption:
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Interactions:
Interactions for Clindamycin:

Clindamycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Therefore, it should be used with caution in patients receiving such agents. Antagonism has been demonstrated between clindamycin and erythromycin in vitro. Because of possible clinical significance, these two drugs should not be administered concurrently.

Chemical IUPAC Name:
N-[2-chloro-1-(3,4,5-trihydroxy-6-methylsulfanyl-tetrahydropyran-2-yl)-propyl]-1-methyl-4-propyl-pyrrolidine-2-carboxamide

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