Clindamycin Phosphate

This page contains recent news articles, when available, and an overview of Clindamycin Phosphate but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Clindamycin Phosphate
(when available)

Pharmacology and use:
Clindamycin is an antibiotic, similar to and a derivative of lincomycin. Clindamycin can be used in topical or systemic treatment. It is effective as an anti-anaerobic antibiotic and antiprotozoal. For the treatment of serious infections caused by susceptible anaerobic bacteria (anaerobes, streptococci, pneumococci, and staphylococci)

Mechanism Of Action:
Systemic/Vaginal-Clindamycin inhibits protein synthesis of bacteria by binding to the 50 S ribosomal subunits of the bacteria. Topical-Clindamycin reduces free fatty acid concentrations on the skin and to suppress the growth of Propionibacterium acnes (Corynebacterium acnes) , an anaerobe found in sebaceous glands and follicles.

News Articles on Clindamycin

Medicis Announces First Quarter 2008 Conference Call and Webcast  -  May 6, 2008
LIDEX(R) (fluocinonide) Cream, 0.05%, VANOS(R) (fluocinonide) Cream, 0.1%, and ZIANA(R) (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel, FOXBusiness

Ipsen and Medicis Announce Acceptance of Reloxin(R) BLA in ...  -  May 18, 2008
LIDEX(R) (fluocinonide) Cream, 0.05%, VANOS(R) (fluocinonide) Cream, 0.1%, and ZIANA(R) (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel, PR-Inside.com (Pressemitteilung),

International Diabetes Federation Grant Supports Diabetes Self ...  -  May 7, 2008
Evoclin(R) (clindamycin phosphate) Foam, 1%; Luxiq(R) (betamethasone valerate) Foam, 0.12%; MimyX(R) Cream; Olux(R) (clobetasol propionate) Foam, Trading Markets (press release),

Stiefel Laboratories, Inc. Acquires ABR Invent and ABR Development  -  May 6, 2008
Evoclin(R) (clindamycin phosphate) Foam, 1%; Luxiq(R) (betamethasone valerate) Foam, 0.12%; MimyX(R) Cream; Olux(R) (clobetasol propionate) Foam, Trading Markets (press release),

Stiefel Laboratories Appoints First Chief Scientific Officer  -  Apr 7, 2008
Evoclin(R) (clindamycin phosphate) Foam, 1%; Luxiq(R) (betamethasone valerate) Foam, 0.12%; MimyX(R) Cream; Olux(R) (clobetasol propionate) Foam, 新�美通(新闻�布),

Medicis Announces the Early Adoption of Online Proxy Materials for ...  -  Apr 8, 2008
LIDEX(R) (fluocinonide) Cream, 0.05%, VANOS(R) (fluocinonide) Cream, 0.1%, and ZIANA(R) (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel, Primenewswire (press release),

DUSA Announces Stiefel's Receipt of Pricing Approval of Levulan ...  -  Mar 6, 2008
Some of the newest and best-known brands include Duac® Topical Gel (clindamycin, 1% - benzoyl peroxide, 5%); Evoclin® (clindamycin phosphate) Foam, 1%; CNNMoney.com

Medicis Announces 2007 Fourth Quarter and Year-End Conference Call ...  -  Feb 26, 2008
LIDEX(R) (fluocinonide) Cream, 0.05%, VANOS(R) (fluocinonide) Cream, 0.1%, and ZIANA(R) (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel, FOXBusiness

Stiefel Laboratories, Inc. Appoints New President  -  Feb 29, 2008
Some of the newest and best- known brands include Duac(R) (clindamycin, 1% - benzoyl peroxide, 5%) Care System (CS); Evoclin(R) (clindamycin phosphate, Biloxi Sun Herald,

KV Pharmaceutical Company Completes Unaudited Fiscal 2007 Results ...  -  Feb 15, 2008
Clindesse(R) (clindamycin phosphate vaginal cream 2%) in the People's Republic of China; -- Concluded an agreement with California-based VIVUS, MSN Money

Medicis to Present At Merrill Lynch Conference  -  Feb 5, 2008
0.05%, VANOS(R) (fluocinonide) Cream, 0.1%, SYNALAR(R) (fluocinolone acetonide), and ZIANA(R) (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel, FOXBusiness

Medicis to Present At 2007 Credit Suisse Annual Healthcare Conference  -  Nov 12, 2007
0.05%, VANOS(R) (fluocinonide) Cream, 0.1%, SYNALAR(R) (fluocinolone acetonide), and ZIANA(R) (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel, CNNMoney.com

Stiefel Laboratories, Inc. Enters into Strategic Collaboration ...  -  Nov 6, 2007
Some of the newest and best-known brands include Duac(R) (clindamycin, 1% -- benzoyl peroxide, 5%) Topical Gel; Evoclin(R) (clindamycin phosphate) Foam, 1%; CNNMoney.com

DUSA Expands Global Sales With Launch of Levulan(R) Kerastick(R ...  -  Oct 1, 2007
Some of the newest and best-known brands include Duac® Topical Gel (clindamycin, 1% - benzoyl peroxide, 5%); Evoclin® (clindamycin phosphate) Foam, 1%; CNNMoney.com

Medicis to Present At Leerink Swann Aesthetics Roundtable Conference  -  Oct 1, 2007
0.05%, VANOS(R) (fluocinonide) Cream, 0.1%, SYNALAR(R) (fluocinolone acetonide), and ZIANA(TM) (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel, CNNMoney.com

Medicis to Present At Thomas Weisel Partners Healthcare Conference  -  Sep 4, 2007
0.05%, VANOS(R) (fluocinonide) Cream, 0.1%, SYNALAR(R) (fluocinolone acetonide), and ZIANA(TM) (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel, CNNMoney.com

Medicis and Hyperion Therapeutics Announce Strategic Collaboration  -  Aug 28, 2007
SYNALAR(R) (fluocinolone acetonide), and ZIANA(TM) (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel, and the over-the-counter brand ESOTERICA(R). CNNMoney.com

Stiefel Laboratories Will Enter Into Private Equity Minority ...  -  Aug 9, 2007
Some of the newest and best- known brands include Duac(R) Topical Gel (clindamycin, 1% -- benzoyl peroxide, 5%); Evoclin(R) (clindamycin phosphate) Foam, CNNMoney.com

Beijing Med-Pharm Hopes To Grow Quickly Through Acquisitions  -  Aug 23, 2007
Clindesse, or clindamycin phosphate vaginal cream, is indicated for the treatment of bacterial vaginosis in non-pregnant women. Seeking Alpha,

Medicis Announces Second Quarter 2007 Conference Call and Webcast  -  Aug 2, 2007
CNNMoney.com0.05%, VANOS(TM) (fluocinonide) Cream, 0.1%, SYNALAR(R) (fluocinolone acetonide), and ZIANA(TM) (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel,

Medicis to Present At Wachovia Securities Nantucket Equity Conference  -  Jun 25, 2007
CNNMoney.com0.05%, VANOS(TM) (fluocinonide) Cream, 0.1%, SYNALAR(R) (fluocinolone acetonide), and ZIANA(TM) (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel,

FDA Sends Letter to KV Pharmaceutical About Clindesse E-Mail/Alert  -  May 22, 2007
PharmaLive.com (press release),The Division of Drug Marketing, Advertising, and Communications (DDMAC) has reviewed an e-Pharm/alert e-mail for Clindesse (clindamycin phosphate) Vaginal

Stiefel Laboratories Moves to Solidify, Enhance Its Leadership ...  -  Apr 23, 2007
PR Newswire (press release),Some of the newest and best- known brands include Duac(R) Topical Gel (clindamycin, 1% - benzoyl peroxide, 5%); Evoclin(R) (clindamycin phosphate) Foam, 1%;

Stiefel Laboratories Moves to Solidify, Enhance Its Leadership ...  -  Apr 23, 2007
PharmaLive.com (press release),Some of the newest and best- known brands include Duac(R) Topical Gel (clindamycin, 1% - benzoyl peroxide, 5%); Evoclin(R) (clindamycin phosphate) Foam, 1%;

Medicis to Present At JPMorgan 25th Annual Healthcare Conference  -  Jan 4, 2007
PharmaLive.com (press release),0.05%, VANOS(TM) (fluocinonide) Cream, 0.1%, SYNALAR(R) (fluocinolone acetonide), ZIANA(TM) (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel,

FDA Approvals: Ziana, Kadian, Polyphenon E  -  Dec 1, 2006
Medscape (subscription)On November 7, the FDA approved clindamycin phosphate 1.2% plus tretinoin 0.025% gel in 30- and 60-g tubes (Ziana, made by Medicis Pharmaceutical Corp) for

Medicis Declares Cash Dividend  -  Dec 14, 2006
Primenewswire (press release),0.05%, VANOS(TM) (fluocinonide) Cream, 0.1%, SYNALAR(R) (fluocinolone acetonide), ZIANA(TM) (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel,

European Zindaclin Licensing Agreements Restructured; Zindaclin ...  -  Dec 13, 2006
Earthtimes.orgZindaclin is a clindamycin phosphate 1% gel for the treatment of mild and moderate acne and was the first once-daily topical treatment launched in Europe.

FDA Approves Ziana(TM) (Clindamycin Phosphate 1.2% and Tretinoin ...  Nov 8, 2006
...announced that the US Food and Drug Administration ("FDA") has approved Ziana(TM) (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel. ... -DG News China punishes manufacturer of killer antibiotic  Oct 16, 2006
The national drug authority banned the use of Xinfu, or clindamycin phosphate glucose, two months ago after alleging it had killed at least six people. ... -TODAYonline, China Antibiotic Maker Loses License  Oct 16, 2006
At least five more deaths � including that of a 74-year-old retired teacher � were later blamed on clindamycin phosphate glucose manufactured by ... -WREX-TV, Brand Names/Synonyms:
Clindamycin Phosphate is also known by the following brand names and/or synonymsChlolincocin; Cleocin; Cleocin Hcl; Cleocin Pediatric; Cleocin Phosphate; Cleocin T; Cleocin T Gel; Cleocin T Lotion; Cleocin T Topical Solution; Clinda-Derm; Clindagel; Clindamicina [Inn-Spanish]; Clindamycin; Clindamycin Hcl; Clindamycin Hydrochloride; Clindamycin Phosphate; Clindamycin [Usan:Ban:Inn]; Clindamycine [French]; Clindamycine [Inn-French]; Clindamycinum [Inn-Latin]; Clindesse; Clindets; Clinimycin; DRG-0011; Dalacin; Dalacin C; Dalacin C Flavored Granules; Dalacin C Phosphate; Dalacin T Topical Solution; Evoclin; HSDB 3037; Sobelin

Drug Category:
Clindamycin Phosphate is categorized under the following by the FDA: Anti-bacterial Agents; Lincomycins; ATC:D10AF01; ATC:G01AA10; ATC:J01FF01

Dosage Forms:
capsules; Intramuscular solution; Intravenousparenteral solution; Topical Solution; Topical Lotion; Topical Gel; Vaginal Cream; Vaginal Ovules

Absorption:
#NAME?

Interactions:
Interactions for Clindamycin:

Clindamycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Therefore, it should be used with caution in patients receiving such agents. Antagonism has been demonstrated between clindamycin and erythromycin in vitro. Because of possible clinical significance, these two drugs should not be administered concurrently.





Chemical IUPAC Name:
N-[2-chloro-1-(3,4,5-trihydroxy-6-methylsulfanyl-tetrahydropyran-2-yl)-propyl]-1-methyl-4-propyl-pyrrolidine-2-carboxamide

:
 
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