Clindamycin

This page contains recent news articles, when available, and an overview of Clindamycin but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Clindamycin
(when available)

Pharmacology and use:
Clindamycin is an antibiotic, similar to and a derivative of lincomycin. Clindamycin can be used in topical or systemic treatment. It is effective as an anti-anaerobic antibiotic and antiprotozoal. For the treatment of serious infections caused by susceptible anaerobic bacteria (anaerobes, streptococci, pneumococci, and staphylococci)

Mechanism Of Action:
Systemic/Vaginal-Clindamycin inhibits protein synthesis of bacteria by binding to the 50 S ribosomal subunits of the bacteria. Topical-Clindamycin reduces free fatty acid concentrations on the skin and to suppress the growth of Propionibacterium acnes (Corynebacterium acnes) , an anaerobe found in sebaceous glands and follicles.

News Articles on Clindamycin

Aurobindo gets USFDA nod for Clindamycin Hydrochloride  -  ‎Aug 27, 2009‎
BO: Quote, Profile, Research) said on Thursday it has received approval from the US Food and Drug Administration for Clindamycin Hydrochloride Capsules. Reuters India

Mylan Inc markets first generic version of BenzaClin for acne ...  -  ‎Aug 28, 2009‎
...company Mylan Inc (Nasdaq:MYL) declared on Thursday the launch of 1% Clindamycin and 5% Benzoyl Peroxide Gel in the market for acne treatment. Trading Markets (press release)

Sanofi-aventis US Introduces BenzaClin(R) Carekit  -  ‎Aug 4, 2009‎
BenzaClin is a topical, prescription acne treatment that combines the acne-fighting power of benzoyl peroxide and clindamycin, and has been shown to reduce PR Newswire (press release)

Pharmacological Approaches for Pediatric Patients With ...  -  ‎Aug 4, 2009‎
9,10 Clindamycin is another commonly used agent in the management of MRSA infections in children. Clindamycin is a derivative of lincomycin that exerts its Ortho SuperSite

Group B strep: the leading cause of serious infection for a newborn  -  ‎Aug 5, 2009‎
Options for women with a serious penicillin allergy include clindamycin and erythromycin; however, these drugs don't always work so the lab has to perform Examiner.com

Strong Body Odor Can Often be Diagnosed and Treated  -  ‎Aug 27, 2009‎
Erythrasma can be easily treated with a topical antibiotic solution, such as erythromycin or clindamycin. More often, however, strong body odor isn't a sign Allentown Morning Call

Updates for DURECT (Nasdaq:DRRX), Peregrine (Nasdaq:PPHM), King ...  -  ‎Aug 28, 2009‎
On 08/27/09, Mylan Inc. (Nasdaq:MYL), announced its subsidiary Mylan Pharmaceuticals Inc. has begun to market 1% Clindamycin and 5% Benzoyl Peroxide Gel American Chronicle

Market Report -- In Play ()  -  ‎Aug 27, 2009‎
Mylan (MYL) announces that its subsidiary Mylan Pharmaceuticals Inc. has begun to market 1% Clindamycin and 5% Benzoyl Peroxide Gel based on an agreement MSN Money

PicksThatMove: www.PicksThatMove.com: "Picks that move" Alerts ...  -  ‎Aug 27, 2009‎
Inc. has begun to market 1% Clindamycin and 5% Benzoyl Peroxide Gel based on an agreement with licensing partner Dow Pharmaceutical Sciences, Trading Markets (press release)

Mylan Begins Marketing First Generic Version of BenzaClin(R) Acne ...  -  ‎Aug 27, 2009‎
11, Dow received FDA approval for its Abbreviated New Drug Application (ANDA) for Clindamycin 1% and Benzoyl Peroxide 5% Gel, a prescription-strength FOXBusiness

Probiotics May Help Cure Vaginosis  -  ‎Aug 19, 2009‎
While the antibiotics clindamycin and metronidazole both cured bacterial vaginosis within two to three weeks in more than 90 percent of cases, About - News & Issues

Environmental changes may lead to problems  -  ‎Aug 20, 2009‎
Bacterial vaginosis is treated by metronidazole (Flagyl, MetroGel) or clindamycin (Cleocin) as tablets or vaginal gels or creams. Clinton Herald

Instead of moving on, Johnson can move up PGA leaderboard  -  ‎Aug 14, 2009‎
Antagonism has been demonstrated in vitro between erythromycin, lincomycin, chloramphenicol, and clindamycin. new york state prescription soma in drug tests Gazette Online

Obagi Medical Products Reports Second Quarter 2009 Financial Results  -  ‎Aug 6, 2009‎
...lesion reduction profile when compared to the leading prescription BPO, combination BPO/ 1-1.2 percent clindamycin and topical clindamycin products. FOXBusiness

Federer y Murray disputarán una de las semifinales del Masters de ...  -  ‎Aug 21, 2009‎
...otherwise healthy nonpregnant patients with BV were randomized to treatment with Flagyl ER once a day for 7 days (n=270) or 2% clindamycin vaginal cream La Prensa Gráfica

Viagra, Cialis, and Levitra – Lost for Choice?  -  ‎Aug 4, 2009‎
Viagra, Cialis and Levitra are no appetizers on a menu that you can make an order to suit Alternative Health Journal

Meda AB (publ) – Interim report, January – June 2009  -  ‎Aug 17, 2009‎
...marketing a patented combination of the active ingredients clindamycin and tretinoin and for a product containing tretinoin as sole active ingredient. PR-Inside.com (Pressemitteilung)

Medicis Reports Second Quarter 2009 Financial Results  -  ‎Aug 5, 2009‎
ZIANA(R) (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel, AMMONUL(R) (sodium phenylacetate and sodium benzoate) Injection 10%/10%, BUPHENYL(R) FOXBusiness

Mylan å­?å…¬å?¸å¼€å§‹åœ¨ç¾Žå›½è¡Œé”€ä¸¤ç§?新产å“?  -  ‎Aug 27, 2009‎
Mylan (MYL)宣布,旗下å­?å…¬å?¸Mylan PharmaceuticaLS Inc.开始行销1% CLindamycin与5% Benzoyl Peroxide Gel,根æ?®å…¬å?¸ä¸ŽæŽˆæ?ƒä¼™ä¼´Dow Pharmaceutical SCiencesçš„ 凤凰网

What is the best empiric therapy for community-acquired cellulitis?  -  13 Jul 2009
For outpatients, trimethoprim/sulfamethox-azole (possibly in combination with a beta-lactam antibiotic), clindamycin, and linezolid can be used to treat The Hospitalist Online

People's Pharmacy: Problems with an antibiotic  -  ‎Jul 12, 2009‎
Q: Your column contained a question regarding diarrhea from the antibiotic clindamycin. Houston Chronicle

Drug-induced diarrhea proved fatal to woman  -  ‎Jul 6, 2009‎
Your column contained a question regarding diarrhea from the antibiotic clindamycin. You advised the writer to see a gastroenterologist. Online Athens

Skin and Skin Structure Infections Are the Second Most Common ...  -  ‎Jun 22, 2009‎
Vancomycin, cefazolin, piperacillin/tazobactam and clindamycin, all in injectable form, are routinely used to treat these infections regardless of the PR Newswire (press release)

Presence of Panton-Valentine Leukocidin in MSSA Not Only Factor in ...  -  ‎Jun 23, 2009‎
Three of the isolates were resistant to fluoroquinolones (43%), and 1 was resistant to both clindamycin and erythromycin (14%). "This study is retrospective DG News

Community-acquired MRSA: Oral doxycycline highly effective  -  ‎Jun 29, 2009‎
Similarly, he says that although clindamycin offers high susceptibility rates in treating CA-MRSA, "Many erythromycin-resistant isolates may develop Modern Medicine

Study: probiotics can increase effectiveness of some antibiotic ...  -  ‎Jul 9, 2009‎
The antibiotics clindamycin and metronidazole both cured BV in over 90% of cases within two to three weeks, although there was a high rate of relapse. Examiner.com

Canfield mom endures painful recovery from flesh eating virus  -  ‎Jul 8, 2009‎
High doses of penicillin and clindamycin are recommended and early and aggressive surgery is often performed to stop the disease spread and remove damaged Youngstown Vindicator

[EMR]-Management of the Drowned Patient  -  ‎Jul 11, 2009‎
Antibiotic choice includes extended-spectrum penicillin plus a -lactamase inhibitor and gentamicin or clindamycin and a fluoroquinolone. TMCnet

Bacterial vaginosis treatments: Probiotics can increase ...  -  ‎Jul 7, 2009‎
The antibiotics clindamycin and metronidazole both cured BV in over 90% of cases within two to three weeks, although there was a high rate of relapse. EurekAlert (press release)

Topical Cream Effective Against Cetuximab-Induced Acne-Like Rash ...  -  ‎Jul 2, 2009‎
Topical clindamycin was applied concomitantly in 12 of 20 and 2 of 38 patients with grade 3 and grade 2 acne-like rash, respectively. DG News

APWR, FDML, CSKI, IP, AIB, NEP. Top Losing Stocks With Negative ...  -  ‎Jun 24, 2009‎
...cough arresting patch, pharyngitis spray, clindamycin metronidazole liniment, ganciclovir injection, loquat syrup, and indigowoad root granule. Insurance News Net (press release)

Fears About Pregnancy and cats Should not stop Those who want to ...  -  ‎Jun 19, 2009‎
Clindamycin and Pyrimethamine are other effective and commonly used drugs, but the later should be supplemented with folic acid as it can cause a deficiency Emediawire (press release)

传染病介ç»?弓形虫感染症  -  ‎Jul 4, 2009‎
...(四) 若病人对sulfonamides无法å¿?å?—,å?¯ä»¥ç”¨Clindamycinå?–代之,å?³å?ˆå¹¶ä½¿ç”¨Clindamycinå’Œpyrimethamine,这是目å‰?治疗爱滋病患者感染弓形虫感染症之第二线è?¯ç‰©ã€‚ 大纪元

10-Q: SINOBIOPHARMA, INC.  -  20 Apr 2009
Currently the product line of Dong Ying China includes Cisatracurium Besylate - a skeletal muscle relaxant, Clindamycin Hydrochloride - an antibiotic for MarketWatch (press release)

GSK to acquire Stiefel Labs in $3.6 billion deal  -  20 Apr 2009
Its products include Duac (benzoyl peroxide/clindamycin) for acne, Olux E (clobetasol) for dermatitis and Soriatane (acitretin) for the treatment of severe Pharma Times

Medicis Announces New Notice of Allowance for SOLODYN(R) 90mg  -  ‎Apr 17, 2009‎
TRIAZ(R) (benzoyl peroxide), LIDEX(R) (fluocinonide) Cream 0.05%, VANOS(R) (fluocinonide) Cream 0.1%, ZIANA(R) (clindamycin phosphate 1.2% and tretinoin GlobeNewsWire (press release)

DoH warns over deadly streptococcal infection  -  ‎Apr 17, 2009‎
Therapy is usually with IV penicillin and clindamycin. Patients with the most severe forms of the infection, such as necrotising fasciitis, may benefit from Healthcare Republic

Acne can persist in adulthood  -  ‎Apr 14, 2009‎
A step up on the treatment ladder is use of antibiotic creams, lotions or ointments containing clindamycin or erythromycin. Another approach is the use of South Coast Today

Endocarditis Prophylaxis: Who and When?  -  ‎Apr 6, 2009‎
If the adult patent is intolerant to penicillins or ampicillin, cephalexin 2 g orally or 50 mg/kg in children, clindamycin 600 mg or 20 mg/kg in children ADVANCE for Physician Assistants

MRSA Infections  -  ‎Apr 13, 2009‎
...linezolid, trimethoprim-sulfamethoxazole, doxycycline, tetracycline or clindamycin. Periodically wash your hands for 15 to 20 seconds with regular soap MSN Health & Fitness

Pediatricians May Be Underutilizing Topical Retinoids for Acne  -  ‎Apr 1, 2009‎
The two acne medications most commonly prescribed by pediatricians included benzoyl peroxide (17.1%) and topical clindamycin (8.4%). AAP Grand Rounds (registration)

S. aureus cultured from nares did not match wound isolates in many ...  -  ‎Mar 30, 2009‎
...with skin and soft tissue infections participating in a trial conducted to compare cephalexin and clindamycin as outpatient treatments. Pediatric SuperSite

Ask the doctor: What can I do about my red nose and cheeks?  -  ‎Mar 30, 2009‎
Treatment usually begins with an antibiotic cream applied to the face - usually clindamycin lotion or metronidazole gel. However, these usually produce Daily Mail

LÃ¥ngsam Ã¥terhämtning efter antibiotika  -  ‎Apr 1, 2009‎
Prolonged impact of a one-week course of clindamycin on Enterococcus spp. in human normal microbiota, Scandinavian Journal of Infectious Diseases, Vol 41, Sveriges Radio

Ä?iá»?u trị bệnh "mÅ©i Ä‘á»? cà chua"  -  ‎Apr 9, 2009‎
Quá trình Ä‘iá»?u trị thông thưá»?ng là dùng loại kem bôi có chứa kháng sinh như clindamycin lotion hay metronidazole dạng gel. Tuy nhiên, các loại thuốc này Dân Trí

Hidrosefali Tedavisinde Enfeksiyon Riski Tartışıldı  -  ‎Apr 3, 2009‎
Bayston aynı zamanda iki farklı antibiyotik (Clindamycin ve Rifampicin) emdirilmiÅŸ olan bu yeni shunt’ların bakterilerle savaÅŸta çok daha güçlü olduklarının Sağlığın Sesi

Brand Names/Synonyms:
Clindamycin is also known by the following brand names and/or synonymsChlolincocin; Cleocin; Cleocin Hcl; Cleocin Pediatric; Cleocin Phosphate; Cleocin T; Cleocin T Gel; Cleocin T Lotion; Cleocin T Topical Solution; Clinda-Derm; Clindagel; Clindamicina [Inn-Spanish]; Clindamycin; Clindamycin Hcl; Clindamycin Hydrochloride; Clindamycin Phosphate; Clindamycin [Usan:Ban:Inn]; Clindamycine [French]; Clindamycine [Inn-French]; Clindamycinum [Inn-Latin]; Clindesse; Clindets; Clinimycin; DRG-0011; Dalacin; Dalacin C; Dalacin C Flavored Granules; Dalacin C Phosphate; Dalacin T Topical Solution; Evoclin; HSDB 3037; Sobelin

Drug Category:
Clindamycin is categorized under the following by the FDA: Anti-bacterial Agents; Lincomycins; ATC:D10AF01; ATC:G01AA10; ATC:J01FF01

Dosage Forms:
capsules; Intramuscular solution; Intravenousparenteral solution; Topical Solution; Topical Lotion; Topical Gel; Vaginal Cream; Vaginal Ovules

Absorption:
- 90% - oral

Interactions:
Interactions for Clindamycin:

Clindamycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Therefore, it should be used with caution in patients receiving such agents. Antagonism has been demonstrated between clindamycin and erythromycin in vitro. Because of possible clinical significance, these two drugs should not be administered concurrently.





Chemical IUPAC Name:
N-[2-chloro-1-(3,4,5-trihydroxy-6-methylsulfanyl-tetrahydropyran-2-yl)-propyl]-1-methyl-4-propyl-pyrrolidine-2-carboxamide

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