Clindamycin

This page contains recent news articles, when available, and an overview of Clindamycin but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Clindamycin (when available)

Pharmacology and use:
Clindamycin is an antibiotic, similar to and a derivative of lincomycin. Clindamycin can be used in topical or systemic treatment. It is effective as an anti-anaerobic antibiotic and antiprotozoal. For the treatment of serious infections caused by susceptible anaerobic bacteria (anaerobes, streptococci, pneumococci, and staphylococci)

Mechanism Of Action:
Systemic/Vaginal-Clindamycin inhibits protein synthesis of bacteria by binding to the 50 S ribosomal subunits of the bacteria. Topical-Clindamycin reduces free fatty acid concentrations on the skin and to suppress the growth of Propionibacterium acnes (Corynebacterium acnes) , an anaerobe found in sebaceous glands and follicles.

News Articles on Clindamycin

10-Q: SINOBIOPHARMA, INC.  -  20 Apr 2009
Currently the product line of Dong Ying China includes Cisatracurium Besylate - a skeletal muscle relaxant, Clindamycin Hydrochloride - an antibiotic for MarketWatch (press release)

GSK to acquire Stiefel Labs in $3.6 billion deal  -  20 Apr 2009
Its products include Duac (benzoyl peroxide/clindamycin) for acne, Olux E (clobetasol) for dermatitis and Soriatane (acitretin) for the treatment of severe Pharma Times

Medicis Announces New Notice of Allowance for SOLODYN(R) 90mg  -  ‎Apr 17, 2009‎
TRIAZ(R) (benzoyl peroxide), LIDEX(R) (fluocinonide) Cream 0.05%, VANOS(R) (fluocinonide) Cream 0.1%, ZIANA(R) (clindamycin phosphate 1.2% and tretinoin GlobeNewsWire (press release)

DoH warns over deadly streptococcal infection  -  ‎Apr 17, 2009‎
Therapy is usually with IV penicillin and clindamycin. Patients with the most severe forms of the infection, such as necrotising fasciitis, may benefit from Healthcare Republic

Acne can persist in adulthood  -  ‎Apr 14, 2009‎
A step up on the treatment ladder is use of antibiotic creams, lotions or ointments containing clindamycin or erythromycin. Another approach is the use of South Coast Today

Endocarditis Prophylaxis: Who and When?  -  ‎Apr 6, 2009‎
If the adult patent is intolerant to penicillins or ampicillin, cephalexin 2 g orally or 50 mg/kg in children, clindamycin 600 mg or 20 mg/kg in children ADVANCE for Physician Assistants

MRSA Infections  -  ‎Apr 13, 2009‎
...linezolid, trimethoprim-sulfamethoxazole, doxycycline, tetracycline or clindamycin. Periodically wash your hands for 15 to 20 seconds with regular soap MSN Health & Fitness

Pediatricians May Be Underutilizing Topical Retinoids for Acne  -  ‎Apr 1, 2009‎
The two acne medications most commonly prescribed by pediatricians included benzoyl peroxide (17.1%) and topical clindamycin (8.4%). AAP Grand Rounds (registration)

S. aureus cultured from nares did not match wound isolates in many ...  -  ‎Mar 30, 2009‎
...with skin and soft tissue infections participating in a trial conducted to compare cephalexin and clindamycin as outpatient treatments. Pediatric SuperSite

Ask the doctor: What can I do about my red nose and cheeks?  -  ‎Mar 30, 2009‎
Treatment usually begins with an antibiotic cream applied to the face - usually clindamycin lotion or metronidazole gel. However, these usually produce Daily Mail

Långsam återhämtning efter antibiotika  -  ‎Apr 1, 2009‎
Prolonged impact of a one-week course of clindamycin on Enterococcus spp. in human normal microbiota, Scandinavian Journal of Infectious Diseases, Vol 41, Sveriges Radio

�?i�?u trị bệnh "mũi đ�? cà chua"  -  ‎Apr 9, 2009‎
Quá trình đi�?u trị thông thư�?ng là dùng loại kem bôi có chứa kháng sinh như clindamycin lotion hay metronidazole dạng gel. Tuy nhiên, các loại thuốc này Dân Trí

Hidrosefali Tedavisinde Enfeksiyon Riski Tartışıldı  -  ‎Apr 3, 2009‎
Bayston aynı zamanda iki farklı antibiyotik (Clindamycin ve Rifampicin) emdirilmiş olan bu yeni shunt’ların bakterilerle savaşta çok daha güçlü olduklarının Sağlığın Sesi

Michigan business news briefs: MGM loses $1.15 billion  -  18 Mar 2009
Allegan-based Perrigo Co. has announced that its partner Cobrek Pharmaceuticals Inc. has filed an abbreviated new drug application for Clindamycin Phosphate Detroit Free Press

Perrigo and Partner Cobrek Confirms Filing for Generic Version of ...  -  ‎Mar 17, 2009‎
Evoclin(R) (clindamycin phosphate) Foam 1% is a topical antibiotic indicated for topical application in the treatment of acne vulgaris, and had sales of PR Newswire (press release)

Patient-Reported Outcomes Favourable With Clindamycin Phosphate ...  -  ‎Mar 11, 2009‎
By Jill Stein SAN FRANCISCO -- March 11, 2009 -- An assessment of patient-reported outcomes with clindamycin phosphate plus low-concentration benzoyl DG News

Market Report -- In Play ()  -  ‎Mar 17, 2009‎
On The Wires Perrigo (PRGO) announces that its partner Cobrek Pharmaceuticals has filed an Abbreviated New Drug Application for Clindamycin Phosphate Foam MSN Money

Obagi Medical Products’ CLENZIderm MD System Effectively Treats ...  -  ‎Mar 6, 2009‎
According to study investigators, when compared to a combination BPO/clindamycin product, the three-step acne system is at least as effective in reducing Earthtimes (press release)

AHA updates advice on strep throat, preventing rheumatic fever  -  ‎Mar 4, 2009‎
So the recommendation now is to start with a narrow-spectrum cephalosporin or clindamycin, he says. For those with severe type 1 allergies to penicillin, TheHeart.Org

Pfizer’s TM Suit Not Entertained: Lack Of Territorial Jurisdiction.  -  ‎Mar 9, 2009‎
...'Clindamycin' the active ingredient in Dalacin is also manufactured by Pfizer's Indian subsidiary. Pfizer stated that they were shocked when they discovered Mondaq News Alerts (registration)

Studies: Staph germs harder than ever to treat  -  ‎Mar 12, 2009‎
But 10 percent of the 824 samples checked also could evade clindamycin, tetracycline, Bactrim or other antibiotics. "The drugs that doctors have typically WHAS 11.com (subscription)

Acanya(TM) Gel, a New Treatment for Moderate to Severe Acne ...  -  ‎Mar 6, 2009‎
Acanya Gel (clindamycin phosphate 1.2% and benzoyl peroxide 2.5%) is indicated for the topical treatment of acne vulgaris in patients 12 years of age or PR Newswire (press release)

New therapies for acne offer choices  -  ‎Mar 11, 2009‎
Acanya contains clindamycin phosphate and benzoyl peroxide. Dill said current recommendations urge limiting the use of oral antibiotics for acne management, Pediatric SuperSite

A 76-Year-Old Man With Recurrent Clostridium difficile–Associated ...  -  ‎Mar 3, 2009‎
2-5 The ability of clindamycin to impair colonization resistance and induce CDI is well known. 3 However, in current medical practice, Journal of American Medical Association (subscription)

Coria Laboratories Announces Acanya(TM) Gel Data Presentations at ...  -  ‎Feb 26, 2009‎
The presentations demonstrate the efficacy and safety of once daily Acanya Gel (clindamycin phosphate 1.2% and benzoyl peroxide 2.5%) in treating patients PR Newswire (press release)

Deadly skin disease targeted  -  ‎Mar 3, 2009‎
Participating patients will be treated with one or more generic antibiotics, including bactrim, keflex and clindamycin, which have shown some effectiveness Arizona Republic

Fighting a feminine problem  -  ‎Mar 12, 2009‎
But my colleague Tieraona Low Dog, MD, tells me some women prefer to use topical vaginal preparations such as metronidazole gel or clindamycin suppositories Calgary Herald

Medicis Announces 2008 Fourth Quarter and Year-End Conference Call ...  -  ‎Feb 23, 2009‎
LIDEX(R) (fluocinonide) Cream 0.05%, VANOS(R) (fluocinonide) Cream 0.1%, and ZIANA(R) (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel, BUPHENYL(R) MSNBC

Coria Laboratories announces launch of Acanya Gel  -  ‎Mar 9, 2009‎
...declared on 6 March the commercial launch of Acanya Gel (clindamycin phosphate 1.2% and benzoyl peroxide 2.5%), which is indicated for the once-daily Trading Markets (press release)

Kardashian Apologizes for 'Insensitive' Chimp Pictures  -  ‎Feb 25, 2009‎
Scientists at NY University College of Medicine have shown that Niacinamide is superior to antibiotics such as Clindamycin in controlling acne. San Francisco Chronicle

Antibiotic Use and Clostridium difficile  -  ‎Mar 5, 2009‎
With regard the individual agents, clindamycin was associated with the greatest risk; for tetracycline and trimethoprim-sulfamethoxazole the risk was Medscape

Community-Acquired MRSA in Children  -  ‎Feb 20, 2009‎
They may be sent home on empiric antibiotics or if susceptibility is confirmed, antimicrobials like clindamycin or vancomycin." Peggy Mercer, BS, RN, ADVANCE for LPNs

Yaz Birth Control Promised Too Much  -  ‎Mar 2, 2009‎
Scientists at NY University College of Medicine have shown that Niacinamide is superior to antibiotics such as Clindamycin in controlling acne. The Frisky

Cobrek�??交Clindamycin Phosphate学�??�?�上市申请  -  ‎Mar 17, 2009‎
Perrigo (PRGO)宣布，�?�作夥伴Cobrek Pharmaceuticals�?�FDA�??交Clindamycin Phosphate Foam 1%学�??�?�上市申请。 �?责声明：本文仅代表作者个人观点，与凤凰网无关。凤凰网

(másnéven: pharyngitis, tonsillitis)  -  ‎Feb 24, 2009‎
Penicillinérzékenység esetén makrolid típusú antibiotikum vagy clindamycin adása jön szóba. Ha a nyelés nagyon fájdalmas, különösen a gyerekeknek érdemes az HáziPatika.com

What treatments work for bacterial vaginosis?  -  Jan 21, 2009
...[4] Clindamycin cream and ovules are oil-based so they might weaken latex condoms and diaphragms.[1] There is some good evidence that these antibiotics will guardian.co.uk,

More Effective Treatment For Pneumonia Following Influenza Found ...  -  Jan 9, 2009
They found that the antibiotics clindamycin and azithromycin, which kill bacteria by inhibiting their protein synthesis, are more effective than a standard Science Daily (press release)

Treating Adult Acne  -  Jan 25, 2009
It surpassed efficacy shown by antibiotics such as Clindamycin. Niacinamide has no side effects unlike antibiotics. Niacinamide is also reputed to increase Best Syndication,

Antibiotic combinations for pelvic inflammatory disease  -  Jan 21, 2009
A drip (IV) of clindamycin three times a day plus gentamicin three times a day into a vein. Then either capsules of clindamycin (brand name Dalacin) four guardian.co.uk,

Antibiotic-Resistant Bugs in the 21st Century — A Clinical Super ...  -  Jan 28, 2009
3 Although such MRSA is commonly susceptible to oral antibiotics such as clindamycin, fluoroquinolones, trimethoprim–sulfamethoxazole, tetracyclines, New England Journal of Medicine (subscription),

What treatments work for chlamydia?  -  Jan 21, 2009
...[1] One good-quality study (called a randomised controlled trial) looked at how well an antibiotic called clindamycin worked for pregnant women with guardian.co.uk,

Childhood MRSA Head and Neck Infections on the Rise  -  Jan 19, 2009
The researchers also found that 47% of all clinical MRSA isolates were resistant to clindamycin as well. Citing a study conducted in the late 1990s showing MedPage Today,

What treatments work for colonic diverticular disease?  -  Jan 21, 2009
About 18 in 21 people (85 percent of people) who took gentamicin and clindamycin got completely better. Other types of studies (called observational guardian.co.uk,

Acne armamentarium Recently approved drugs increase dermatologists ...  -  Jan 19, 2009
However, patients using the fixed combination of clindamycin/benzoyl peroxide benefited with significantly greater reductions in all lesion types, Modern Medicine,

10-Q: SINOBIOPHARMA, INC.  -  Jan 14, 2009
Currently the product line of Dong Ying China includes Cisatracurium Besylate - a skeletal muscle relaxant, Clindamycin Hydrochloride - an antibiotic for MarketWatch (press release)

Rise In Antibiotic-Resistant Pediatric Infections  -  Jan 22, 2009
The researchers also noted that about 46 percent of the MRSA infections studied were resistant to the non-penicillin antibiotic clindamycin, commonly used PakTribune.com,

Clinicians puzzled by an unusual, elusive postsurgical sequela  -  Jan 13, 2009
The organism was susceptible to ampicillin/sulbactam, ceftriaxone, cefotetan, penicillin G, clindamycin, imipenem, and chloramphenicol. Clinical Advisor,

First Reports of MRSA Isolation in US Swine and Hog Farmers  -  Jan 26, 2009
...oxacillin and tetracycline, but susceptible to a range of other antibiotics. The human isolates had variable sensitivity to erythromycin and clindamycin. MedPage Today,

Medicis to Present At JP Morgan Healthcare Conference  -  Jan 8, 2009
LIDEX(R) (fluocinonide) Cream 0.05%, VANOS(R) (fluocinonide) Cream 0.1%, and ZIANA(R) (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel, MSNBC

Mad rantings about politics, evolution, and microbiology  -  Jan 24, 2009
Antibiotic resistance in these Iowan ST398 isolates is unusual too: many are resistant to clindamycin, but not erythromycin. This is a very odd phenotype ScienceBlogs

Cellulitis and erysipelas  -  Jan 21, 2009
Some of the antibiotics normally given (and their brand names) are: benzylpenicillin (Penicillin G), clindamycin (Dalacin C) and erythromycin (Erythrocin). guardian.co.uk,

Vaccine Prevention of Late-Onset Neonatal Group B Streptococcal ...  -  Jan 21, 2009
Frequent resistance of clinical group B streptococci isolates to clindamycin and erythromycin. Obstet Gynecol. 1998;92:258-261. Hickman ME, Rench MA, Medscape

Fla. Company Buys Three Service Centers  -  Jan 9, 2009
They found that the antibiotics clindamycin and azithromycin, which kill bacteria by inhibiting their protein synthesis, are more effective than a standard Memphis Daily News,

YOUR HEALTH  -  Jan 9, 2009
So is clindamycin ointment, an antibiotic. If rosacea fails to respond to medicines applied to the skin, oral antibiotics are the next step on the treatment Kilgore News Herald,

Multilevel Diskitis and Vertebral Osteomyelitis After Diskography  -  Jan 9, 2009
Klessig HT, Showsh SA, Sekorski A. The use of intradiscal antibiotics for discography: an in vitro study of gentamicin, cefazolin, and clindamycin. Spine . Ortho SuperSite,

研究：抗�?�性MRSA感染增加逾一�?  -  Jan 24, 2009
...令医生担心的是，46%的感染案例中的MRSA细�?�对一�?常用�?�对付�?�盘尼西林类的特效抗细�?��?�物clindamycin 大纪元

美 소아 MRSA �?경부 �?염 급�?  -  Jan 20, 2009
...아울러, MRSA �?염 중 46%가 지역사회 �?염 MRSA�? �?�히 사용�?�는 항�?제�?� ‘�?�린다마�?�신’(clindamycin)�? 저항�?� 보여 우려�??다. �?��? 연구진�?� 지역사회 �?염 MRSA 디지틀보사,

�?��? 후 사�? 95% �?�?� �??렴 효과�?�?� 치료법 발견  -  Jan 11, 2009
12�?� St. Jude 소아연구병�? 연구팀�?� '�?염질환저�?'�? �?힌 연구결과�? �?�하면 단백질 합성�?� 차단 세균�?� 죽�?�는 �?�린다마�?�신(clindamycin)과 아지스로 Medical Today,

Bacterial vaginosis often recurs  -  Dec 23, 2008
Clindamycin is another effective treatment that can be used in a way similar to metronidazole to prevent relapses. A newer bacterial vaginosis medicine is Kilgore News Herald,

Standard of care for MRSA infections  -  Dec 23, 2008
...doxycycline, minocycline, trimethoprim-sulfamethoxazole [TMP-SMX], or clindamycin [Cleocin]), and don't be afraid to combine oral agents. Clinical Advisor,

Valeant continues derma buyout streak  -  Dec 15, 2008
The buyout hands Valeant the newly-approved treatment for mild-to-moderate acne, Acanya (clindamycin phosphate 1.2% and benzoyl peroxide), which is expected Scrip World Pharmaceutical News (subscription),

Medicis Declares Cash Dividend  -  Dec 17, 2008
LIDEX(R) (fluocinonide) Cream 0.05%, VANOS(R) (fluocinonide) Cream 0.1%, and ZIANA(R) (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel, MarketWatch

Malaria in Refugees From Tanzania—King County, Washington, 2007  -  Dec 9, 2008
The patient received quinidine and clindamycin, recovered, and was transitioned to atovaquone-proguanil before discharge. He was discharged on October 19, Journal of American Medical Association (subscription),

Valeant to Acquire Dow Pharmaceutical Sciences, Inc. for $285 Million  -  Dec 10, 2008
On October 23, 2008 , the Food and Drug Administration approved the Dow NDA for a combination product, Acanya(TM) Gel (clindamycin phosphate 1.2% and SYS-CON Media,

Medicis and IMPAX Announce R&D Collaboration and Settlement  -  Dec 1, 2008
LIDEX(R) (fluocinonide) Cream 0.05%, VANOS(R) (fluocinonide) Cream 0.1%, and ZIANA(R) (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel, MarketWatch

Doctor warns on rampant strains of MRSA  -  Dec 13, 2008
...told the conference that antibiotic use increases the risk of C diff infection, especially the use of the cephalosporin family and the drug clindamycin. Irish Times,

A Deadly Bug Invades  -  Dec 5, 2008
Some—such as Bactrim, clindamycin, and tetracycline—haven’t commonly been used to treat staph infections. There’s also a range of super-powerful antibiotics Parade Magazine

Negative Reactions to Antibiotics  -  Dec 1, 2008
In terms of the rate of ED visits, meaning the number of ED visits for every 10000 outpatient prescription visits, sulfonamides and clindamycin, Natural News.com,

Modern Drugs to Treat Acne  -  Dec 1, 2008
Antibiotics used against acne are tetracycline variants, erythromycin, clindamycin, stivamycin, sulfacetamide and trimethaprim. Best Syndication,

<22> 예�?� 사슴�?� 옮기는 무서운 병  -  Dec 23, 2008
...�?� 질병�?� clindamycin 투여로 치료를 하는�?� 물론 조기 발견치 못하면 사�?�? �?�르는 무서운 질병�?�다. 메릴랜드 주 정부 통계�? 따르면 메릴랜드 주�? 사슴 수가 24 약업신문,

美国FDA批准Arcutis Pharma公�?�的Acany  -  Dec 1, 2008
...一家�?立的专业皮肤科产�?研究机构Arcutis 制�?�公�?�于2008年11月24日对外宣布，美国FDA 已批准其1.2%克林霉素磷酸酯+2.5%过氧化苯甲酰�?方�?胶（clindamycin 生物谷,

Brand Names/Synonyms:
Clindamycin is also known by the following brand names and/or synonymsChlolincocin; Cleocin; Cleocin Hcl; Cleocin Pediatric; Cleocin Phosphate; Cleocin T; Cleocin T Gel; Cleocin T Lotion; Cleocin T Topical Solution; Clinda-Derm; Clindagel; Clindamicina [Inn-Spanish]; Clindamycin; Clindamycin Hcl; Clindamycin Hydrochloride; Clindamycin Phosphate; Clindamycin [Usan:Ban:Inn]; Clindamycine [French]; Clindamycine [Inn-French]; Clindamycinum [Inn-Latin]; Clindesse; Clindets; Clinimycin; DRG-0011; Dalacin; Dalacin C; Dalacin C Flavored Granules; Dalacin C Phosphate; Dalacin T Topical Solution; Evoclin; HSDB 3037; Sobelin

Drug Category:
Clindamycin is categorized under the following by the FDA: Anti-bacterial Agents; Lincomycins; ATC:D10AF01; ATC:G01AA10; ATC:J01FF01

Dosage Forms:
capsules; Intramuscular solution; Intravenousparenteral solution; Topical Solution; Topical Lotion; Topical Gel; Vaginal Cream; Vaginal Ovules

Absorption:
- 90% - oral

Interactions:
Interactions for Clindamycin:

Clindamycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Therefore, it should be used with caution in patients receiving such agents. Antagonism has been demonstrated between clindamycin and erythromycin in vitro. Because of possible clinical significance, these two drugs should not be administered concurrently.

Chemical IUPAC Name:
N-[2-chloro-1-(3,4,5-trihydroxy-6-methylsulfanyl-tetrahydropyran-2-yl)-propyl]-1-methyl-4-propyl-pyrrolidine-2-carboxamide

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