Cinalukast

This page contains recent news articles, when available, and an overview of Cinalukast but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Cinalukast (when available)

Pharmacology and use:
Used in the treatment of asthma, cinalukast selectively antagonizes leukotriene D4 (LTD₄) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. Cinalukast inhibits the actions of LTD₄ at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus. For Protection against second- phase inflamation in exercise-induced bronchoconstriction and Asthma.

Mechanism Of Action:
Binds to the cysteinyl leukotriene receptor. The cysteinyl leukotrienes (LTC4, LTD₄, LTE4) are products of arachidonic acid metabolism and are released from various cells, including mast cells and eosinophils. These eicosanoids bind to cysteinyl leukotriene receptors (CysLT) found in the human airway. Cysteinyl leukotrienes and leukotriene receptor occupation have been correlated with the pathophysiology of asthma, including airway edema, smooth muscle contraction, and altered cellular activity associated with the inflammatory process, which contribute to the signs and symptoms of asthma.

News Articles on Cinalukast

Brand Names/Synonyms:
Cinalukast is also known by the following brand names and/or synonymsCinalukast; Cinalukast [Usan:Inn]

Drug Category:
Cinalukast is categorized under the following by the FDA: Antiarrhythmic Agents; ATC:R03DC

Dosage Forms:
Not Available

Absorption:
Not Available

Interactions:
Not Available

Chemical IUPAC Name:
4-[3-[2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl]amino-2,2-diethyl-4-oxo-butanoicacid

:

Web health.mongabay.com

Disclaimer:

Contact a physician with regard to health concerns. Email requests for further health information will be discarded.

The materials contained on this Web site are for informational purposes only and do not constitute health or medical advice. Use of information on this site does not create or constitute any kind of agreement or contract between you and the owners or users of this site, the owners of the servers upon which it is housed, or anyone else who is in any way connected with this site.

Many links on health.mongabay.com lead to other sites. health.mongabay.com does not sponsor, endorse or otherwise approve of the materials appearing in such sites. Nor is health.mongabay.com responsible for dead or misdirected links.