Chlorhexidine Gluconate

This page contains recent news articles, when available, and an overview of Chlorhexidine Gluconate but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Chlorhexidine Gluconate (when available)

Pharmacology and use:
Chlorhexidine, a topical antimicrobial agent, is used orally to treat mucositis, mouth infections, denture stomatitis, ulcerative stomatitis, acute necrotizing ulcerative gingivitis (ANUG), gingivitis, periodontitis and topically as an antiseptic and disinfectant. For reduction of pocket depth in patients with adult periodontitis, used as an adjunct to scaling and root planing procedures; For prevention of dental caries, oropharyngeal decontamination in critically ill patients; hand hygiene in health-care personnel; general skin cleanser; and catheter site preparation and care.

Mechanism Of Action:
Chlorhexidine's antimicrobial effects are associated with the attractions between chlorhexidine (cation) and negatively charged bacterial cells. After chlorhexidine is absorpted onto the organism's cell wall, it disrupts the integrity of the cell membrane and causes the leakage of intracellular components of the organisms.

News Articles on Chlorhexidine

Chlorhexidine gluconate–impregnated sponges reduced rate of ...  -  ‎Apr 14, 2009‎
...“Use of chlorhexidine gluconate–impregnated dressings decreases the rate of major catheter-related infection when the baseline rate is lower than two per HemOncToday

Use Of Antibacterial Associated With Reduced Risk Of Catheter ...  -  ‎Mar 31, 2009‎
Use of a chlorhexidine gluconate–impregnated sponge (CHGIS) as part of the dressing over the skin at the site of insertion of the intravascular catheter may Science Daily (press release)

Causes of Periodontal Disease  -  ‎Apr 1, 2009‎
...daily can save you from serious gum problems: • Use antiseptic mouthwash with chlorhexidine gluconate or hydrogen peroxide as directed by your dentist. Best Syndication

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...消委會指出，漱�?�水�?牌眾多，�?方�?�有�?�?�，葡�?�糖酸氯己定（chlorhexidine gluconate）雖證實有效抑制牙�?�膜�?防止牙周病，但長期使用�?�令牙齒表�?��?�?�牙漬，更會香港新浪網

Clinical Intervention Eliminates Heel Ulcer Incidents in ICU  -  ‎Mar 3, 2009‎
Sage is pioneering Interventional Patient Hygiene with industry-leading brands such as Toothette(R) oral care, Sage(R) 2% Chlorhexidine Gluconate Cloths for PR Newswire (press release)

Steps to Lower Your Chance of Getting a Hospital Acquired Infection  -  Jan 31, 2009
Also see the study by Daryl S. Paulson, "Efficacy Evaluation of a 4% Chlorhexidine Gluconate as a Full-Body Shower Wash," published by the Association for InjuryBoard.com,

What treatments work for recurrent mouth ulcers?  -  Jan 21, 2009
Hunter L, Addy M. Chlorhexidine gluconate mouthwash in the management of minor aphthous stomatitis. British Dental Journal. 1987; 162: 106-110. guardian.co.uk,

AquaDent Pet Oral Health Product Contains Deadly Xylitol  -  Jan 15, 2009
5, Chlorhexidine gluconate. According to Dr. Eric Dunayer, veterinarian and toxicologist for the ASPCA Animal Poison Control Center, there appears to be a Natural News.com,

What treatments work for bad breath?  -  Jan 21, 2009
We found research to say that chemicals called cetylpyridinium chloride and chlorhexidine gluconate work for bad breath. But there's no reason why any brand guardian.co.uk,

Patients' Bath Basins Increase Risk for Hospital-Acquired Infections  -  Jan 29, 2009
Sage is pioneering Interventional Patient Hygiene with industry-leading brands such as Toothette(R) oral care, Sage(R) 2% Chlorhexidine Gluconate Cloths for PR Newswire (press release),

Experts divided over whether mouthwash is a cancer causer  -  Jan 12, 2009
...hexetidine, methyl salicylate, menthol, chlorhexidine gluconate, benzalkonium chloride, cetylpyridinium chloride, methylparaben, hydrogen peroxide, TheMedGuru,

New In-Service Training Program Available For Chlorascrub(TM)  -  Nov 13, 2008
Chlorascrub™ is a preoperative and preinjection(1) skin preparation with a unique 3.15% w/v Chlorhexidine Gluconate (CHG) / 70% v/v Isopropyl Alcohol (IPA) PR Web (press release),

High Growth Reported for the World Pharmaceuticals Market Brief  -  Nov 18, 2008
Hydrochlorothiazide, Furosemide Oral, Chlorhexidine Gluconate, Gabapentin, Ibuprofen, Levothyroxine, Metoprololtartrate, Albuterol nebulizer solution, MarketWatch

Author : Resurgent Health and Medical  -  Sep 30, 2008
Using Resurgent's proprietary Chlorhexidine Gluconate (CHG) sanitizing solution, the single cycle removes over 99.9% of pathogens and continues to kill Earthtimes (press release),

Resurgent Health and Medical's handwashing systems removed 99.997 ...  -  Aug 21, 2008
Using Resurgent's proprietary Chlorhexidine Gluconate 2% (CHG2%) sanitizing solution, Resurgent's hand hygiene products remove over 99.9% of pathogens and MarketWatch

Ecolab Introduces Preoperative Antiseptic Bathing Kit to Reduce ...  -  Aug 19, 2008
...(BUSINESS WIRE)--Ecolab Inc. today introduced its Preoperative Antiseptic Bathing Kit with chlorhexidine gluconate (CHG), a new product developed for Business Wire (press release),

Ecolab Inc announces shipment of Preoperative Antiseptic Bathing Kit  -  Aug 20, 2008
...declared on 19 August that the company has launched its Preoperative Antiseptic Bathing Kit with chlorhexidine gluconate (CHG), a new product developed Trading Markets (press release),

Company news  -  Aug 19, 2008
Ecolab Inc., St. Paul, introduced its Preoperative Antiseptic Bathing Kit with chlorhexidine gluconate (CHG), a new product developed for hospitals to Minneapolis Star Tribune,

China Sky One Medical, Inc. Announces 26 New Drugs in Clinical Trials  -  Sep 10, 2008
Three drugs, including Chlorhexidine Gluconate, Cetylpyridinium Chloride and Compound Chlorhexidine, are gargles for the treatment of toothache; Earthtimes (press release),

Ecolab wants patients to be clean all over  -  Aug 21, 2008
The kits, which contain a 4-ounce bottle of chlorhexidine gluconate (CHG) skin disinfectant, two wrapped washcloths and cleaning instructions, are expected Minneapolis Star Tribune,

Preventing Ventilator-Associated Pneumonia Could Silver-Coated ...  -  Aug 19, 2008
Prevention of nosocomial infection in cardiac surgery by decontamination of the nasopharynx and oropharynx with chlorhexidine gluconate: a randomized Journal of American Medical Association (subscription),

SpongeTech(R) Delivery Systems, Inc. CEO Interviewed Live on Steve ...  -  Aug 19, 2008
Ecolab Inc. (NYSE: ECL) recently introduced its Preoperative Antiseptic Bathing Kit with chlorhexidine gluconate (CHG), a new product developed for Financial News USA (press release),

MedWatch - 2% Chlorhexidine Gluconate Cloth Patient Preoperative ...  -  07 Aug 2008
Sage Products informed healthcare professionals of the voluntary recall of limited lots of 2% Chlorhexidine Gluconate Cloth Patient Preoperative Skin RMGH Health News,

Meritech's CleanTech(R) ELF and CleanTech(R) IC receive NSF ...  -  Aug 5, 2008
Using Meritech's proprietary Chlorhexidine Gluconate (CHG) sanitizing solution, the single cycle removes over 99.9% of pathogens and continues to kill germs MarketWatch

Hospitals, Healthcare Providers Will Save with Premier ...  -  Jul 11, 2008
Thee 36-month contracts, effective August 1, 2008, are available to all acute care and continuum of care members of the Premier healthcare alliance. MarketWatch

FDA warns against boguss cancer cures  -  Jul 16, 2008
Sage Products announced a voluntary recall of limited lots of 2% Chlorhexidine Gluconate (CHG) Cloth Patient Preoperative Skin Preparation product that was Gridley Herald,

Resurgent Health and Medical Launches CleanTracker at APIC Annual ...  -  Jul 8, 2008
Using Resurgent’s proprietary Chlorhexidine Gluconate (CHG) sanitizing solution, the single cycle removes over 99.9% of pathogens and continues to kill Business Wire (press release),

Sage Products Inc. Recalls 2 Percent Chlorhexidine Gluconate Cloth ...  -  03 Jul 2008
SAGE PRODUCTS ANNOUNCED A VOLUNTARY RECALL OF LIMITED LOTS OF 2% CHLORHEXIDINE GLUCONATE (CHG) CLOTH PATIENT PREOPERATIVE SKIN PREPARATION PRODUCT. US Recall News (press release),

Sage Products Recalls Medical Device for Bacterial Contamination  -  Jul 1, 2008
Sage Products Inc. has issued a recall of some lots of 2% Chlorhexidine Gluconate Cloth Patient Preoperative Skin Preparation because it could be Newsinferno.com,

Company recalls preoperative skin preparation cloth  -  Jul 1, 2008
A recall of 2% chlorhexidine gluconate (CHG) cloth patient preoperative skin preparation has been announced by Sage Products Inc., the manufacturer of the AAP News (subscription)

PDI Donates Infection Prevention Supplies To Direct Relief  -  Jun 14, 2008
Chlorascrub™ is the only FDA approved Chlorhexidine Gluconate (CHG) product available for use prior to surgery and injection, consisting of 3.15% Emediawire (press release),

Meritech's CleanTech Handwashing System Used at Mike's Pizza in ...  -  Jun 26, 2008
Using Meritech's proprietary Chlorhexidine Gluconate (CHG) sanitizing solution, the single cycle removes over 99.9% of pathogens and continues to kill germs PR-Inside.com (Pressemitteilung),

Meritech’s CleanTech Handwashing System Used at Mike’s Pizza in ...  -  Jun 26, 2008
Using Meritech’s proprietary Chlorhexidine Gluconate (CHG) sanitizing solution, the single cycle removes over 99.9% of pathogens and continues to kill germs Business Wire (press release),

3M Health Care launches new high-performance surgical mask  -  Jun 24, 2008
Other products include 3M™ Avagard™ (Chlorhexidine Gluconate 1% Solution and Ethyl Alcohol 61% w/w) Surgical and Healthcare Personnel Hand Antiseptic with EurekAlert (press release),

Meritech Celebrates its 20th Anniversary with New Offices, Staff ...  -  02 Jun 2008
Using Meritech’s proprietary chlorhexidine gluconate (CHG) sanitizing solution, the single cycle is designed to remove more than 99.9 percent of pathogens Infection Control Today,

Meritech Celebrates Its 20th Anniversary with New Offices, Staff ...  -  May 29, 2008
Using Meritech's proprietary Chlorhexidine Gluconate (CHG) sanitizing solution, the single cycle removes over 99.9% of pathogens and continues to kill germs PR-Inside.com (Pressemitteilung),

Risk Factors in Total Joint Arthroplasty: Comparison of Infection ...  -  May 21, 2008
Patients were prepped with betadine solution or DuraPrep Surgical solution (3M, St Paul, Minnesota) or chlorhexidine gluconate solution if they had a Ortho SuperSite,

Meritech's CleanTech Handwashing System to be Used in Newly ...  -  May 19, 2008
Using Meritech’s proprietary Chlorhexidine Gluconate (CHG) sanitizing solution, the single cycle removes over 99.9% of pathogens and continues to kill germs Earthtimes (press release),

Cardinal Health Completes Enturia Acquisition  -  May 15, 2008
The products use proprietary disposable applicators to deliver a clinically preferred concentration of chlorhexidine gluconate (CHG) that penetrates the WebWire (press release),

Cardinal Health Completes Enturia Acquisition  -  May 12, 2008
The products use proprietary disposable applicators to deliver a clinically preferred concentration of chlorhexidine gluconate (CHG) that penetrates the CNNMoney.com (press release)

3M buying Canadian medical products maker  -  Apr 1, 2008
The company detailed that buy will bring line of chlorhexidine gluconate and alcohol-based products to 3M offering for infection prevention, Bizjournals.com,

3M Acquires Les Entreprises Solumed  -  Apr 1, 2008
The products use chlorhexidine gluconate, or CHG, and alcohol to reduce bacteria. "The addition of Solumed positions 3M for growth in the fast-growing Houston Chronicle,

MRSA Infections Increasing in All Surgical Fields  -  Apr 20, 2008
The recommend taking "every appropriate step" to prevent wound infections in facial plastic surgery, including chlorhexidine gluconate preoperative Occupational Health Safety,

Resurgent Health and Medical announces that Weirton Medical Center ...  -  Apr 14, 2008
Using Meritech's proprietary Chlorhexidine Gluconate (CHG) sanitizing solution, the single cycle removes over 99.9% of pathogens and continues to kill germs Business Wire (press release),

New data on 3M's Tegaderm CHG  -  Apr 7, 2008
3M™ Tegaderm™ CHG (chlorhexidine gluconate) IV Securement Dressing, demonstrated excellent long-term, surface antimicrobial activity against diverse EurekAlert (press release),

3M acquires Les Entreprises Solumed  -  Apr 1, 2008
The products use chlorhexidine gluconate, or CHG, and alcohol to reduce bacteria. 'The addition of Solumed positions 3M (nyse: MMM - news - people ) for Forbes,

3M Canada Buys Medical Product Developer  -  Apr 1, 2008
Solumed brings a chlorhexidine gluconate (CHG) and alcohol-based line of products to 3M’s offering for infection prevention. “The addition of Solumed Modern Distribution Management,

3M Acquires Les Entreprises Solumed Inc.  -  Apr 1, 2008
Terms of the transaction were not Solumed brings a chlorhexidine gluconate (CHG) and alcohol-based line of products to 3M's already robust core offering for PR-Inside.com (Pressemitteilung),

Cardinal Health Agrees to Acquire Chloraprep® Manufacturer for ...  -  Mar 4, 2008
ChloraPrep® products are cleared by the Food and Drug Administration and use a clinically preferred concentration of chlorhexidine gluconate (CHG) and WebWire (press release),

3M ESPE moisturizing hand antiseptic tackles tough bacteria  -  Feb 29, 2008
It comes in a convenient 500 mL pump bottle, is compatible with chlorhexidine gluconate, and both latex and non-latex gloves. Dental Economics,

Meritech Announces That Jose Pepper's and Cactus Grill Have ...  -  Feb 19, 2008
Using Meritech's proprietary Chlorhexidine Gluconate (CHG) sanitizing solution, the single cycle removes over 99.9% of pathogens and continues to kill germs Centre Daily Times,

New Practices Dramatically Affect Care  -  Jan 14, 2008
For example, in switching to chlorhexidine gluconate to clean central line ports of entry, facilities discovered the products came in two different Nurse.com,

Preoperative Decolonization of Methicillin-resistant ...  -  Jan 11, 2008
Randomized controlled trial of chlorhexidine gluconate for washing, intranasal mupirocin, and rifampin and doxycycline versus no treatment for the Ortho SuperSite,

Do You Have Clean Hands?  -  Jan 28, 2008
Using Meritech's proprietary Chlorhexidine Gluconate (CHG) sanitizing solution, the single cycle removes over 99.9% of pathogens and continues to kill germs Business Wire (press release),

Chlorhexidine Gluconate Cloths May Help Reduce Primary Bloodstream ...  -  Oct 25, 2007
October 25, 2007 — Daily cleansing of patients in medical intensive care units (micus) with chlorhexidine gluconate–impregnated cloths was simple and Medscape (subscription)

Chlorhexidine-Based Solutions Prevent Catheter-Related Infection  -  Oct 25, 2007
...with 5% povidone-iodine in 70% ethanol or with a combination of 0.25% chlorhexidine gluconate, 0.025% benzalkonium chloride, and 4% benzylic alcohol. Medscape (subscription)

Effectiveness of Chlorhexidine Bathing to Reduce Catheter ...  -  Oct 22, 2007
...with chlorhexidine gluconate (CHG) have a lower incidence of primary bloodstream infections (bsis) compared with patients bathed with soap and water. Archives of Internal Medicine

Soap and Water May not be Enough to Fight MRSA Superbug  -  Nov 8, 2007
In these situations, an antimicrobial soap containing chlorhexidine gluconate (CHG) kills MRSA and other staph infections and provides a protective barrier Earthtimes,

Antiseptic-impregnated Cloths May Be More Effective Than ...  -  Oct 11, 2007
By John Gever NEW ORLEANS, LA -- October 11, 2007 -- Cloths impregnated with chlorhexidine gluconate (CHG), a common antiseptic agent, appear more likely to DG News

Deal with Bad Breath: Choose the Mouthwash Carefully  -  Sep 23, 2007
Then the ingredients such as Cetylpyridinium Chloride and Chlorhexidine Gluconate fight against plaque build ups and gingivitis. However, you have to wait PR-GB.com (press release),

Ensure Your Oral Hygiene with the Help of Mouthwash  -  Sep 23, 2007
In addition to fluoride, the mouthwashes also use such ingredients as thymol, eucalyptol, hexetidine, methyl salicylate, menthol, chlorhexidine gluconate, PR-GB.com (press release),

Molnlycke Drives 'Home' the Fight Against Staph and Other MRSA ...  -  Sep 20, 2007
...antimicrobial agents with residual activity like chlorhexidine gluconate (CHG) found in cleansers such as Hibiclens(R), according to Twomey. PR Newswire (press release),

Novation Signs New Technology Agreement With Sage Products  -  Sep 19, 2007
...a small veteran-owned business based in Cary, Ill. for its 2% chlorhexidine gluconate (CHG) cloths, effective July 1, 2007 through June 30, 2010. Market Wire (press release)

Smile Wipes: Wilton business looks to keep hands clean  -  Aug 15, 2007
For years, Mr. Spinoso had been using a product called chlorhexidine gluconate to keep his pet shop free from germs, and after looking into it a bit more, Wilton Bulletin,

New product wipes out germs with a smile  -  Aug 16, 2007
Instead, the antimicrobial agent Chlorhexidine Gluconate [CHG] is used as the active germ fighting ingredient. It's not immediately clear whether hand Wilton Villager,

New Solution to Sickness Promises to Wipe Out Germs with a 'Smile'  -  Aug 14, 2007
Smile Wipes contain the safest solution available, Chlorhexidine Gluconate (CHG), which was approved by the United States Food and Drug Administration as an PR-GB.com (press release),

New Solution to Sickness Promises to Wipe Out Germs with a 'Smile'  -  Aug 2, 2007
PR Web (press release),Smile Wipes contain the safest solution available, Chlorhexidine Gluconate (CHG), which was approved by the United States Food and Drug Administration as an

Brand Names/Synonyms:
Chlorhexidine Gluconate is also known by the following brand names and/or synonymsBioscrub; Brian Care; C6143; CHEMBANK1360; CHLORHEXIDINE BAS; Chlorhexidin; Chlorhexidin [Czech]; Chlorhexidine; Chlorhexidine Base; Chlorhexidine Gluconate; Chlorhexidine, Free Base; Chlorhexidinum [Inn-Latin]; Cida-Stat; Cloresidina [Dcit]; Clorhexidina [Inn-Spanish]; Decanoylacetaldehyde Sodium Sulfide; Dyna-Hex; E-Z Scrub; Exidine; Fimeil; HSDB 7196; Hexadol; Hibiclens; Hibidil; Hibiscrub; Hibisol; Hibispray; Hibistat; Hibitane; Microderm; Nolvasan; Oro-Clense; Peridex; Periochip; Periogard; Pharmaseal Scrub Care; Prevacare R; Rotersept; Savloclens; Savlon Babycare; Sodium Houttuyfonamide; Soretol; Steri-Stat; Sterido; Sterilon; Superspray; Tubulicid

Drug Category:
Chlorhexidine Gluconate is categorized under the following by the FDA: Anti-bacterial Agents; Anti-Infectives; ATC:A01AB03; ATC:B05CA02; ATC:D08AC02; ATC:D09AA12; ATC:R02AA05; ATC:S01AX09; ATC:S02AA09; ATC:S03AA04

Dosage Forms:
Oral rince; Pellet, extended- release; PerioChip (in a biodegradable matrix of hydrolyzed gelatin [cross-linked with glutaraldehyde]) (glycerin) (purified water); CREAM; DRESSING; GEL; LOTION; OINTMEN; SPONGE

Absorption:
absorption of chlorhexidine from the gastrointestinal tract is very poor

Interactions:
Interactions for Chlorhexidine:

No information provided.

Chemical IUPAC Name:
1-[amino-[6-[amino-[amino-(4-chlorophenyl)amino-methylidene]amino-methylidene]aminohexylimino]methyl]imino-N-(4-chlorophenyl)-methanediamine

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