Chlorhexidine

This page contains recent news articles, when available, and an overview of Chlorhexidine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Chlorhexidine (when available)

Pharmacology and use:
Chlorhexidine, a topical antimicrobial agent, is used orally to treat mucositis, mouth infections, denture stomatitis, ulcerative stomatitis, acute necrotizing ulcerative gingivitis (ANUG), gingivitis, periodontitis and topically as an antiseptic and disinfectant. For reduction of pocket depth in patients with adult periodontitis, used as an adjunct to scaling and root planing procedures; For prevention of dental caries, oropharyngeal decontamination in critically ill patients; hand hygiene in health-care personnel; general skin cleanser; and catheter site preparation and care.

Mechanism Of Action:
Chlorhexidine's antimicrobial effects are associated with the attractions between chlorhexidine (cation) and negatively charged bacterial cells. After chlorhexidine is absorpted onto the organism's cell wall, it disrupts the integrity of the cell membrane and causes the leakage of intracellular components of the organisms.

News Articles on Chlorhexidine

Chlorhexidine gluconate–impregnated sponges reduced rate of ...  -  ‎Apr 14, 2009‎
Using chlorhexidine-impregnated sponge dressings with intravascular catheters reduced the risk for major catheter-related infections by 60% among patients HemOncToday

Use Of Antibacterial Associated With Reduced Risk Of Catheter ...  -  ‎Mar 31, 2009‎
ScienceDaily (Apr. 1, 2009) — For critically ill patients in intensive care units, use of a sponge containing the antimicrobial agent chlorhexidine Science Daily (press release)

Causes of Periodontal Disease  -  ‎Apr 1, 2009‎
...daily can save you from serious gum problems: • Use antiseptic mouthwash with chlorhexidine gluconate or hydrogen peroxide as directed by your dentist. Best Syndication

Why Do We Continue To Have MRSA In Our Hospitals?  -  ‎Apr 8, 2009‎
Or how hard can it be to advise patients to reduce their risk of infection by showering with Chlorhexidine soap daily before elective surgery? InjuryBoard.com

Reducing harm in critical care  -  ‎Mar 30, 2009‎
Include chlorhexidine antisepsis kits in trolleys or grab-bags storing central line equipment. If a pre-packed central line kit includes povidone-iodine Nursing Times

Boise hospitals win honors for preventing medication errors ...  -  ‎Apr 2, 2009‎
Hospital officials also started using mouthwash with Chlorhexidine, a chemical antiseptic, for patients who needed ventilators or had received IdahoStatesman.com

Shaving best before catheter insertion, say researchers  -  ‎Mar 28, 2009‎
They compared disinfection protocols using two commonly used antiseptic solutions - povidone iodine and chlorhexidine - and assessed whether clipping or Horsetalk

Fleas a problem, especially in warm weather  -  ‎Apr 14, 2009‎
I usually recommend using a soft wipe containing chlorhexidine (available from your vet). Sometimes a very soft toothbrush works better to get into the Gilroy Dispatch

Initiative to cut catheter infections expands  -  ‎Apr 5, 2009‎
The program includes five evidence-based procedures the CDC has recommended, such as including chlorhexidine in the central-line kits used in ICUs. American Medical News (subscription)

A New Strategy to Improve Quality Rewarding Actions Rather Than ...  -  ‎Mar 31, 2009‎
If chlorhexidine washes are needed to reduce infection rates, then that process should be measured. The incentives to improve and the measurement of the Journal of American Medical Association (subscription)

Full-Mouth Rehabilitation and Bite Management of Severely Worn ...  -  ‎Mar 30, 2009‎
The prepared teeth were cleaned with pumice, followed by hydrogen peroxide and chlorhexidine (Consepsis, Ultradent; South Jordan, UT). Express Press Release (press release)

PAR MARTINE BETTI-CUSSO  -  ‎Apr 10, 2009‎
Et la Mini (17,90€), ultracompacte, est idéale pour les excursions journalières avec ses compresses à la chlorhexidine, à l'arnica et ses pansements Le Figaro

漱�?�水增牙漬�??味覺  -  ‎Apr 15, 2009‎
...消委會指出，漱�?�水�?牌眾多，�?方�?�有�?�?�，葡�?�糖酸氯己定（chlorhexidine gluconate）雖證實有效抑制牙�?�膜�?防止牙周病，但長期使用�?�令牙齒表�?��?�?�牙漬，更會香港新浪網

More Steps to Prevent Hospital Acquired Infections  -  ‎Mar 11, 2009‎
In addition to the Chlorhexidine soap showers I previously recommended, ask your surgeon to have you tested for methicillin-resistant Staphylococcus aureus InjuryBoard.com

Inmates testing ways to stop MRSA  -  ‎Feb 24, 2009‎
...is testing washcloths treated with a chemical antiseptic called chlorhexidine to see if the cloths help reduce the spread of the bacterial infections. MarketWatch (press release)

How to kill the bacteria that can cause bad breath  -  ‎Mar 16, 2009‎
Mouthwash containing antibacterial ingredients such as chlorhexidine and cetylpyridinium do the job of getting rid of bad breath better than a placebo, Irish Independent

APIC Offers Tips for Reducing Infection Risk in Outpatient Clinics  -  ‎Mar 14, 2009‎
Follow your doctor's instructions to shower or cleanse your surgical site with a special product (eg, chlorhexidine) before arriving for surgery or other Occupational Health Safety

The links between oral and systemic health  -  ‎Feb 26, 2009‎
The best therapy for BON is chlorhexidine 0.12% rinses with penicillin VK added for painful lesions. (Pain may be associated with bacterial infection, Clinical Advisor

Clinical Intervention Eliminates Heel Ulcer Incidents in ICU  -  ‎Mar 3, 2009‎
Sage is pioneering Interventional Patient Hygiene with industry-leading brands such as Toothette(R) oral care, Sage(R) 2% Chlorhexidine Gluconate Cloths for PR Newswire (press release)

清�?让皮肤拥有纯净的享�?�  -  ‎Mar 16, 2009‎
...也就是脓包，则�?�选择一些添加Trichosan或Chlorhexidine的洗剂，但这些洗剂的效果，其实都远�?�?�直接使用治疗�?�春痘的�?��?，�?�样的观点，也适用在抗�?��?�皂中。北京广播网

Keeping 'em alive  -  Feb 3, 2009
The letter outlined the evidence supporting the use of chlorhexidine 1 and asked the CEOs to stock chlorhexidine in their hospitals before implementing the ScienceBlogs

Infections Growing At Hospitals Near You  -  Feb 3, 2009
...•If you need a “central line�? catheter, ask your doctor about the benefits of one that is antibiotic-impregnated or coated with silver chlorhexidine to InjuryBoard.com,

Steps to Lower Your Chance of Getting a Hospital Acquired Infection  -  Jan 31, 2009
Also see the study by Daryl S. Paulson, "Efficacy Evaluation of a 4% Chlorhexidine Gluconate as a Full-Body Shower Wash," published by the Association for InjuryBoard.com,

What treatments work for recurrent mouth ulcers?  -  Jan 21, 2009
Mouthwashes and gels containing an antiseptic called chlorhexidine may make your ulcers less painful and go away faster. Mouthwashes, lozenges, pastes or guardian.co.uk,

What treatments work for minor burns and scalds?  -  Jan 21, 2009
...[1] Some dressings are soaked in a disinfectant called chlorhexidine. It's normally used to clean wounds. We don't know if using a dressing soaked in guardian.co.uk,

What treatments work for bad breath?  -  Jan 21, 2009
We found research to say that chemicals called cetylpyridinium chloride and chlorhexidine gluconate work for bad breath. But there's no reason why any brand guardian.co.uk,

Mouth ulcers  -  Jan 21, 2009
Chlorhexidine is an antiseptic that can make your ulcers less painful and go away faster. But doctors aren't sure if it can stop you getting repeat attacks guardian.co.uk,

Keeping Kids Cavity-Free Before They're Ever Born: CariFree ...  -  Jan 18, 2009
...caries (71-74% lower decayed, missing, or filled teeth) than even those children whose mothers used fluoride or an antimicrobial agent, Chlorhexidine. PR Web (press release),

New Mallinckrodt(TM) SealGuard Evac(TM) Endotracheal Tube Reduces ...  -  Feb 2, 2009
...as head-of-bed elevation, stress-ulcer prophylaxis, oral chlorhexidine cleaning and sedation and weaning protocols, in both the test and control groups. StreetInsider.com (subscription),

Patients' Bath Basins Increase Risk for Hospital-Acquired Infections  -  Jan 29, 2009
Sage is pioneering Interventional Patient Hygiene with industry-leading brands such as Toothette(R) oral care, Sage(R) 2% Chlorhexidine Gluconate Cloths for PR Newswire (press release),

Infections grip US hospitals  -  Jan 23, 2009
...•If you need a “central line�? catheter, ask your doctor about the benefits of one that is antibiotic-impregnated or coated with silver chlorhexidine to Fort Wayne Journal Gazette,

Nosebleeds in children  -  Jan 21, 2009
The cream that's usually used is a combination of chlorhexidine (an antiseptic) and neomycin (an antibiotic). The brand name is Naseptin. guardian.co.uk,

Treatments for gum disease  -  Jan 21, 2009
You may have: A mouthwash containing a chemical called chlorhexidine. It helps to kill bacteria and reduce the build up of plaque. guardian.co.uk,

AquaDent Pet Oral Health Product Contains Deadly Xylitol  -  Jan 15, 2009
5, Chlorhexidine gluconate. According to Dr. Eric Dunayer, veterinarian and toxicologist for the ASPCA Animal Poison Control Center, there appears to be a Natural News.com,

Canadian Contagious Equine Metritis Update  -  Jan 9, 2009
CEMO is susceptible to most common disinfectants, including chlorhexidine, ionic and nonionic detergents, and sodium hypochlorite. 3. Standardbred Canada,

Experts divided over whether mouthwash is a cancer causer  -  Jan 12, 2009
...hexetidine, methyl salicylate, menthol, chlorhexidine gluconate, benzalkonium chloride, cetylpyridinium chloride, methylparaben, hydrogen peroxide, TheMedGuru,

�?用�?�?��?�?�腔病患�?能�??廢?�?�水正確使用零風險  -  Feb 2, 2009
...以�?�有Chlorhexidine 中時電�?報,

CEM Infects US Horses  -  Dec 23, 2008
Treatment involves strict cleansing and applying chlorhexidine, and then nitrofurazone ointment once the chlorhexidine dries. Hopefully, these animals can Grit Magazine

Standard of care for MRSA infections  -  Dec 23, 2008
Many protocols use chlorhexidine showers daily or every other day (to avoid skin irritation and breakdown) along with alcohol-based hand gels; Clinical Advisor,

Recurrent boils demand persevering treatment  -  Dec 18, 2008
During the day, she should wash her hands frequently with Hibiclens (chlorhexidine 4 percent), an antibacterial soap. Staph can cling to her fingers, SouthCoastToday.com,

Pitfalls in efficacy testing - how important is the validation of ...  -  Dec 1, 2008
Effective neutralization of active agents is essential to obtain valid efficacy results, especially when non-volatile active agents like chlorhexidine 7thSpace Interactive (press release),

Pneumonia rates in ICU can be halved by cleaning teeth  -  Dec 16, 2008
Toothbrushes were used at least once a day by 85.5% of critical care nurses and chlorhexidine mouthwash products were used routinely by 50.5% of the 103 Nursing Times,

Physician Autonomy and Informed Decision Making Finding the ...  -  Dec 23, 2008
For example, deciding to sterilize the skin with chlorhexidine and wash hands before inserting a central line are not decisions patients should make. Journal of American Medical Association (subscription),

Controlled Clinical Trials and Practice-based Research in Dentistry  -  21 Nov 2008
An economic evaluation of a chlorhexidine chip for treating chronic periodontitis. The CHIP (CHlorhexidine In Periodontitis) study. Journal of Dental Research,

Probiotic Mouthwash May Prevent Ventilator-Associated Pneumonia  -  Nov 5, 2008
5 -- A mouthwash containing the probiotic species Lactobacillus plantarum 299 was as effective as chlorhexidine at eliminating disease-causing pathogens MedPage Today,

New In-Service Training Program Available For Chlorascrub(TM)  -  Nov 13, 2008
Chlorascrub™ is a preoperative and preinjection(1) skin preparation with a unique 3.15% w/v Chlorhexidine Gluconate (CHG) / 70% v/v Isopropyl Alcohol (IPA) PR Web (press release),

Blue Dolphin Dives into Trachea  -  Oct 30, 2008
22-, 25-, and 18-gage needles; double swivel connector; Chlorhexidine/alcohol prep solution; suture with needle; CSR wrap; and prep tray. Medgadget.com,

High Growth Reported for the World Pharmaceuticals Market Brief  -  Nov 18, 2008
Hydrochlorothiazide, Furosemide Oral, Chlorhexidine Gluconate, Gabapentin, Ibuprofen, Levothyroxine, Metoprololtartrate, Albuterol nebulizer solution, MarketWatch

Hospital germs  -  Nov 17, 2008
These include hand hygiene, providing maximum barriers (gowns, gloves, mask, cap, drape), skin antisepsis with chlorhexidine, removing catheters as soon as New Straits Times,

Preventing Super Bug Infections  -  Nov 17, 2008
Five days prior to surgery, bathe each day with chlorhexidine soap, which is available without a prescription, to prevent dangerous bacteria from North Florida NewsDaily,

How Washington hospitals unleashed a MRSA epidemic  -  Nov 19, 2008
To get rid of the germ, Velte scrubbed himself with over-the-counter soap containing chlorhexidine, an antibacterial chemical. He also wiped his house down PhysOrg.com,

Nurses should use SSD cream to treat burns, says Cochrane review ...  -  Nov 18, 2008
...gels and biosynthetic dressings can be more effective for treatment of moderate burns than SSD or standard chlorhexidine-impregnated gauze dressings. Nursing Times (registration),

Professional Sports Teams Should Use MRSA Screening and Other ...  -  Oct 29, 2008
Players who test positive should bathe with chlorhexidine soap for three to five days to remove the bacteria from the skin before the operation and, MarketWatch

Probiotics May Stave Off Pneumonia  -  Nov 7, 2008
...critically-ill patients from ventilator-associated pneumonia (VAP) just as effectively as antiseptics, such as chlorhexidine (CHX), or antibiotics. Natural Products Marketplace,

EU experts assess the role of biocides in antibiotic resistance  -  Nov 14, 2008
Triclosan is used in disinfectants, cosmetics, toothpaste, cleaning products, paint, textiles and plastic products, while chlorhexidine is found in many Scrip World Pharmaceutical News (subscription),

Friendly Bacteria Take On Dangerous Foes  -  Nov 13, 2008
To prevent infection, patients are usually given the antiseptic chlorhexidine (CHX). But Dr Bengt Klarin and colleagues at the University Hospital in Lund, StaffNurse.com,

Probiotic prevents infections in ventilated patients  -  Nov 7, 2008
Probiotic bacteria worked as well as the antiseptic chlorhexidine in preventing pneumonia in 50 ventilated patients in a Swedish hospital, SmartBrief,

Study Shows . . .  -  Oct 29, 2008
...“The concentrations of chlorhexidine found in contact lens maintenance solutions are not high enough to kill pathogenic strains�? said Valladares. The Asian Pacific Post,

New guidelines have been published that aim to improve the ...  -  Oct 27, 2008
Antiseptic preparation with povidone-iodine or chlorhexidine or similar should be used on the patient's skin at the surgical site immediately before Hospital Healthcare Europe,

프로바�?�오틱유산균 중환�? '�??렴' 예방  -  Nov 5, 2008
...연구결과 �?� 같�?� 프로바�?�오틱�?� �??렴 예방�?� 위해 사용�?�는 �?�로르헥시딘(chlorhexidine)등�?� 항균제와 같�?� 기능�?� 하면서�?� �?연�?�?� 바 알레르기등 부작용�?� 거�?� 마�?��?��?�리,

“好�?细�?��?护病人�?�?�感染-研究  -  Nov 6, 2008
...他们�?�现，使用�??为�?物乳�?��?�299的益生�?�擦拭的病人和使用抗生素氯己定(chlorhexidine 路�?社,

Les maladies de peau du cheval  -  Nov 13, 2008
Utilisez des produits contenant du chlorhexidine ou de la Bétadine et évitez d’acheter des produits qui n’affichent pas les composants sur l’emballage. Waliboo,

La dermatophytose du cheval  -  Nov 13, 2008
Afin de limiter l’évolution de la maladie, les chevaux peuvent être traités avec une large gamme de traitements antifongiques comme le chlorhexidine, Waliboo,

프로바�?�오틱스, 중�?환�? �??렴 �?염 예방  -  Nov 12, 2008
...�?�공호�?�기를 장착한 환�?들�?게서 �?�히 발�?하는 ‘�?�공호�?�기 관련 �??렴’(VAP)�?� 예방하는 효과가 소�?�제 �?�로르헥시딘(CHX; Chlorhexidine)�? 비견�?� 정�?��?�는 것. 약업신문,

Brand Names/Synonyms:
Chlorhexidine is also known by the following brand names and/or synonymsBioscrub; Brian Care; C6143; CHEMBANK1360; CHLORHEXIDINE BAS; Chlorhexidin; Chlorhexidin [Czech]; Chlorhexidine; Chlorhexidine Base; Chlorhexidine Gluconate; Chlorhexidine, Free Base; Chlorhexidinum [Inn-Latin]; Cida-Stat; Cloresidina [Dcit]; Clorhexidina [Inn-Spanish]; Decanoylacetaldehyde Sodium Sulfide; Dyna-Hex; E-Z Scrub; Exidine; Fimeil; HSDB 7196; Hexadol; Hibiclens; Hibidil; Hibiscrub; Hibisol; Hibispray; Hibistat; Hibitane; Microderm; Nolvasan; Oro-Clense; Peridex; Periochip; Periogard; Pharmaseal Scrub Care; Prevacare R; Rotersept; Savloclens; Savlon Babycare; Sodium Houttuyfonamide; Soretol; Steri-Stat; Sterido; Sterilon; Superspray; Tubulicid

Drug Category:
Chlorhexidine is categorized under the following by the FDA: Anti-bacterial Agents; Anti-Infectives; ATC:A01AB03; ATC:B05CA02; ATC:D08AC02; ATC:D09AA12; ATC:R02AA05; ATC:S01AX09; ATC:S02AA09; ATC:S03AA04

Dosage Forms:
Oral rince; Pellet, extended- release; PerioChip (in a biodegradable matrix of hydrolyzed gelatin [cross-linked with glutaraldehyde]) (glycerin) (purified water); CREAM; DRESSING; GEL; LOTION; OINTMEN; SPONGE

Absorption:
absorption of chlorhexidine from the gastrointestinal tract is very poor

Interactions:
Interactions for Chlorhexidine:

No information provided.

Chemical IUPAC Name:
1-[amino-[6-[amino-[amino-(4-chlorophenyl)amino-methylidene]amino-methylidene]aminohexylimino]methyl]imino-N-(4-chlorophenyl)-methanediamine

:

Web health.mongabay.com/health

Disclaimer:

Contact a physician with regard to health concerns. Email requests for further health information will be discarded.

The materials contained on this Web site are for informational purposes only and do not constitute health or medical advice. Use of information on this site does not create or constitute any kind of agreement or contract between you and the owners or users of this site, the owners of the servers upon which it is housed, or anyone else who is in any way connected with this site.

Many links on health.mongabay.com/health lead to other sites. health.mongabay.com/health does not sponsor, endorse or otherwise approve of the materials appearing in such sites. Nor is health.mongabay.com/health responsible for dead or misdirected links.