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CetirizineThis page contains recent news articles, when available, and an overview of Cetirizine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.Overview: Cetirizine (when available) Cetirizine, the active metabolite of the piperazine H1-receptor antagonist hydroxyzine, is used to treat chronic idiopathic urticaria, perennial allergic rhinitis, seasonal allergic rhinitis, allergic asthma, physical urticaria, and atopic dermatitis. For the relief of symptoms associated with seasonal allergic rhinitis, perennial allergic rhinitis and the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria Mechanism Of Action: Cetirizine competes with histamine for binding at H1-receptor sites on the effector cell surface, resulting in suppression of histaminic edema, flare, and pruritus. The low incidence of sedation can be attributed to reduced penetration of cetirizine into the CNS as a result of the less lipophilic carboxyl group on the ethylamine side chain. News Articles on Cetirizine EU Drug Watchdog Backs Wider Use Of Merck, Sanofi Drugs - 02 Jun 2008 ...(Directive 83/2001/EC as amended) for Zyrtec/Reactine and associated names (cetirizine), from UCB, used as antiallergic and antihistaminic agent. EasyBourse.com, Teva Introduces Budeprion XL - May 30, 2008 NORTH WALES, Pa., May 30, 2008— Teva Pharmaceuticals is pleased to announce the introduction and availability of Budeprion XL® [Bupropion Hydrochloride PharmaLive.com (press release), Q&A with Dr Thomas Stuttaford on tackling hay fever - May 28, 2008 Q4: My doctor prescribes cetirizine for me as a one-a-day tablet. It works quite well except that when the pollen is at it height I find that the hay fever Times Online, Specialized Health Products Reports Financial Results for First ... - May 7, 2008 BOUNTIFUL, Utah--(BUSINESS WIRE)--Specialized Health Products International, Inc., (“Specialized Health Products�) (OTCBB:SHPI), a leading developer, Business Wire (press release), Perrigo Co. reports strong third quarter - May 6, 2008 That included $97 million in new-product revenue, "led by Omeprazole and Cetirizine, strong sales in the cough/cold, analgesic and smoking-cessation product MLive.com, Perrigo 3Q profit more than doubles - May 6, 2008 The result was aided by the introduction of Omeprazole and Cetirizine and strong sales of allergy medications. Perrigo also raised the lower end of its Forbes, UPDATE 1-Perrigo Q3 results top market estimates - May 6, 2008 ...rose 39 percent to $503.7 million and included $97 million in new product revenue, led by its heartburn drug, Omeprazole, and allergy drug, Cetirizine. Reuters Antihistamines bad for kids - May 12, 2008 A smaller study involving 20 school-age children found that cetirizine (Zyrtec) clinically improves cough due to pollen allergy and antihistamines were Deccan Herald, Pricey allergies - May 14, 2008 For example, if you rely on Zirtek, its active ingredient is Cetirizine dihydrocholride. So find an alternative generic Cetirizine dihydrocholride with the GMTV, Sneezy rider ... the diesel Ford Focus - May 7, 2008 PIRITEZE ALLERGY SYRUP – £4.99 for 70ml bottle: A sugar-free syrup containing the antihistamine cetirizine. By JANE SYMONS THE popularity of diesel cars The Sun, Perrigo doubles net, share drops - May 6, 2008 ...we delivered record sales and earnings with successful launches of two of the largest products in our 120-year history, Omeprazole and Cetirizine. Globes, Schering Plough First Quarter Earnings Call - May 28, 2008 ...in more than 30 years, as well as higher sales of OTC CLARITIN, which grew despite the aggressive launch of a competing OTC cetirizine allergy product. 123Jump.com, Current Discounts And Deals #44 - May 20, 2008 And hayfever medication Cetirizine is also now available at Chemist4u.com at the bargain price of 99p for 30 tablets - as long as you order six packs Motley Fool UK, Perrigo and Cobrek plan to develop generic Luxiq - May 27, 2008 Sales for the period increased some 39 per cent to $504m helped by the firm's successful launch of generic versions of the allergy drug Zyrtec (cetirizine) In-PharmaTechnologist.com, Never mind the polls, how’s your LDL? - May 26, 2008 ...cetirizine for his nasal allergies; and a multivitamin. With that many medications it sounds like he’s eligible for a home medicines review. 6minutes, Sneezing Season - May 25, 2008 Zyrtec (cetirizine HCl), the nation's top-selling prescription allergy medicine, went off-patent in December 2007. Pfizer ceded OTC manufacturing and RedOrbit, Perrigo enjoys record third quarter, but gets pounded by investors - May 6, 2008 Besides Omeprazole, Perrigo introduced Cetirizine tablets, a generic form of Zyrtec allergy medication. "We had our two largest product launches within a MLive.com, McCain's Doctors Say the State of the Candidate's Health Is Excellent - May 23, 2008 In addition to the simvastatin and hydrochlorothiazide, McCain takes a baby aspirin to prevent blood clots, cetirizine (Zyrtec) for nasal allergies, MedPage Today, Interim Report: UCB off to a good - May 14, 2008 In line with expectations, net sales and royalty income of Zyrtec®(cetirizine) in the US market decreased significantly due to thepatent expiration in Ad-Hoc-News (Pressemitteilung), Interim Report: UCB off to a good start in 2008 - May 14, 2008 In line with expectations, net sales and royalty income of Zyrtec® (cetirizine) in the US market decreased significantly due to the patent expiration in Euronext (persbericht), Hard to Control Allergies - May 7, 2008 ...they simply take an allergy medication, such as Allegra (fexofenadine), Claritin (Loratadine), Singulair (montelukast), or Zyrtec (cetirizine), About - News & Issues, 20% of Drugs Sold in India Fake, Fear Experts - May 13, 2008 Some examples are: price of Nise (nimesulide) of Dr Reddy's has shot up from Rs 27 to 32 — an increase of 18.5%, while the price of Relant (cetirizine and Daijiworld.com, UCB's Cimzia gets approval in the USA for Crohn's disease - 23 Apr 2008 ...which is a vitally important drug for UCB, which lost patent protection on its biggest earner – the allergy drug Zyrtec (cetirizine) – last year. Pharma Times (subscription), Schering-Plough Reports Financial Results for First Quarter of 2008 - 23 Apr 2008 ...in more than 30 years, as well as higher sales of OTC CLARITIN, which grew despite the aggressive launch of a competing OTC cetirizine allergy product. Earthtimes, Taro Receives Final FDA Approval for Cetirizine Hydrochloride Oral ... - Apr 22, 2008 The product will be marketed by Taro's US affiliate, Taro Pharmaceuticals USA, Inc. Taro's Cetirizine Oral Solution is bioequivalent to McNeil Consumer Genetic Engineering News (press release), Reviewers Say Children Should Not Take Antihistamines for Chronic ... - Apr 21, 2008 A smaller study involving 20 school-aged children found that cetirizine (Zyrtec) clinically improves cough due to pollen allergy. DG News Vital: Ask The Doc - Apr 21, 2008 Cetirizine or loratadine are the best for breastfeeding women, ask your pharmacist for advice. Q WHAT can I do about my smelly feet? Glasgow Daily Record, Perrigo to produce new children's allergy treatment - Apr 14, 2008 The company announced Monday it has approval to market a 1mg/mL version of Children's Cetirizine Hydrochloride Oral Solution and Children's Cetirizine MLive.com, What's in a name? - Apr 7, 2008 But buy your cetirizine in generic form and you'll hand over only £2.99 for 30 tablets. It pays to shop around, says Nyss. Boots and Superdrug own brands of Guardian, Meda acquires rights to Orexo's patented products - Apr 15, 2008 OX-NLA is a patented nasal spray formulation with the antihistamine substance cetirizine, which is being developed for the treatment of allergic and Pharmaceutical Business Review Perrigo wins FDA approval for allergy medication - Apr 15, 2008 Cetirizine Hydrochloride oral solution is the basis for the drug. The generic drug is comparable to Zyrtec, produced by McNeil Consumer Healthcare, Globes, Children should not take antihistamines for chronic cough ... - Apr 16, 2008 A smaller study involving 20 school-age children found that cetirizine (Zyrtec) clinically improves cough due to pollen allergy. Hindu, Michigan business briefs - Apr 15, 2008 Perrigo's cetirizine hydrochloride oral solution is comparable to McNeil Consumer Healthcare's children's Zyrtec, which had 2007 sales of about $80 million, Detroit Free Press, Perrigo Announces Approval for Over-the-Counter Children's ... - Apr 17, 2008 Perrigo Company has announced that it has received final approval from the FDA to manufacture and market over-the-counter (OTC) Children's Cetirizine Pharmaceutical Processing, Pfizer earnings suffer as patent expiries cause more damage - Apr 18, 2008 Zyrtec (cetirizine) revenues collapsed 75% to $117 million, while loss of patent protection also hurt the antidepressant Zoloft (sertraline), which was down Pharma Times (subscription), Perrigo Announces Approval for Over-the-Counter Children's ... - Apr 14, 2008 ...(OTC) Children's Cetirizine Hydrochloride Oral Solution (Allergy) and Children's Cetirizine Hydrochloride Oral Solution (Hives-Relief), 1mg/mL. Earthtimes, A Pill Pusher For Your Portfolio - Apr 10, 2008 ...focuses on less common molecules that are difficult to develop, such as pentoxiifylline, tramadol, midazolam, fenofibrate, fluticasone and cetirizine. Forbes, Orexo and Meda in a Potential Billion SEK Deal - Apr 13, 2008 OX-NLA is a patented nasal spray formulation with the antihistamine substance cetirizine. The liposomes in OX-NLA give the product unique features. Business Wire (press release), Challenging Your Course For Indoor And Outdoor Allergy Symptom Relief - Apr 7, 2008 Do not take XYZAL® if you are allergic to XYZAL®, cetirizine or ZYRTEC. Be sure to tell your doctor if you have kidney disease. North American Press Syndicate, Generic Drugs Gain the Spotlight - Mar 31, 2008 In January, a number of retailers synchronized the rollout of products containing generic antihistamine cetirizine hydrochloride with the over-the-counter In-Store Marketing Institute (Subscription), Big blow for UCB as CHMP rejects Cimzia, again - Mar 25, 2008 ...protection on its biggest earners – the allergy drug Zyrtec (cetirizine) and the antiepileptic Keppra (levetiracetam) – in 2007 and 2009, respectively. Pharma Times (subscription), Perrigo Says Teva Gets FDA Approval For Cetirizine Drug - Mar 6, 2008 ...received approval from the Food and Drug Administration for its abbreviated new drug application for over-the-counter cetirizine hydrochloride, CNNMoney.com Perrigo Company to Market Over-the-Counter Cetirizine ... - Mar 6, 2008 New Drug Application (ANDA) for over-the-counter Cetirizine Hydrochloride, Pseudoephedrine Hydrochloride Extended-Release Tablets, 5 mg/120 mg. PR Newswire (press release), Perrigo: Teva gets FDA final approval for OTC generic version of ... - Mar 6, 2008 The product, cetirizine hydrochloride, pseudoephedrine hydrochloride, will be marketed by Perrigo under store brand labels and is indicated for 12-hour CNNMoney.com Market Report -- In Play (PRGO) - Mar 6, 2008 Perrigo to market over-the-counter cetirizine hydrochloride, pseudoephedrine hydrochloride extended-release tablets Co announced that its partner, MSN Money I've got an itch - Mar 3, 2008 Traditionally these are somewhat sedative (eg Piriton) but newer agents such as cetirizine do not enter the brain so are safer when driving etc. Manchester Evening News, HEALTHY CHILDREN: Prescription drugs now over counter - Feb 9, 2008 The first is Zyrtec (cetirizine), a medication that is used to treat allergy symptoms. Zyrtec is in the class of low-sedating antihistamines. Wicked Local Brockton, UCB gets FDA approval for new version of Xyzal allergy drug - Feb 19, 2008 Both formulations of Xyzal, which is a follow-up to UCB’s blockbuster antihistamine Zyrtec (cetirizine), are now approved for use in adults and children Pharma Times (subscription), Know More About Allergic Rhinitis - Mar 1, 2008 Included in this category are cetirizine and fexofenadine. These types of antihistamines will unlikely cause drowsiness. Nasal sprays are the most common TamilStar.com, LPGA Pro, Jill McGill, Encourages Indoor and Outdoor Allergy ... - Feb 28, 2008 The use of XYZAL(R) is contraindicated in: patients with a known hypersensitivity to levocetirizine or any of the ingredients of XYZAL(R) or to cetirizine CNNMoney.com (press release) Perrigo increases fiscal year guidance - 06 Feb 2008 ...approval from the FDA for its Abbreviated New Drug Application (ANDA) for non-prescription Cetirizine Hydrochloride Tablets, in 5 and 10 mg dosages. Trading Markets (press release), Perrigo benefits from rival's woes - 06 Feb 2008 Perrigo also began shipments last month of store brand, over-the-counter cetirizine hydrochloride tablets, which are comparable to McNeil Consumer The Grand Rapids Press - MLive.com, Caraco Pharmaceutical Laboratories, Ltd. Announces FDA Approval to ... - Jan 14, 2008 Cetirizine HCl Chewable, which will be marketed as two separate OTC products in two strengths, 5 mg and 10 mg, is an antihistamine drug, which is used to CNNMoney.com Wal-Mart Becomes One of the First to Offer Over-the-Counter Zyrtec - Jan 23, 2008 Wal-Mart will also sell non-prescription Zyrtec-D(R) (cetirizine HCl, pseudoephedrine HCl), which will be available behind the pharmacy counter. CNNMoney.com Zyrtec Makes a Crowded Debut - Jan 29, 2008 Walgreens, CVS, Rite Aid, Kroger and Meijer are among the retailers to introduce private-label versions of Zyrtec under its chemical name, Cetirizine In-Store Marketing Institute (Subscription), Perrigo Reports Record Sales and Earnings for Second Quarter ... - Feb 5, 2008 On December 28, 2007, Perrigo announced it received final approval from the FDA for its Abbreviated New Drug Application (ANDA) for OTC Cetirizine FOXBusiness Michigan business briefs - Jan 15, 2008 Cetirizine HCl chewable, which will be marketed as two separate products in the two strengths, is an antihistamine drug used to treat allergies, Detroit Free Press, Caraco Pharma gets FDA nod to market allergy drug - Jan 14, 2008 The US Food and Drug Administration approved Caraco Pharma's abbreviated new drug application for Cetirizine Hydrochloride chewable tablets for children, Reuters Generic Zyrtec - Jan 7, 2008 It is stored for the advice diagnosis or generic cetirizine hydrochloride news. At its February 3 2006. Or if your symptoms improve. Vogue.com, Caraco labs to open new plant in Wixom - Jan 26, 2008 Last month, Caraco obtained final approval from the US Food and Drug Administration for the company's "over-the-counter" version of cetirizine hydrochloride Oakland Press, FDA OKs Generic Zyrtec - Jan 9, 2008 Pfizer also makes Zyrtec oral syrup for children and a 12-hour version, Zyrtec-D (cetirizine HCl/pseudoephedrine HCl), both of which were recently approved FDA news (subscription), Caraco gets OK for generic diabetes drug - Jan 17, 2008 Earlier this month, the FDA approved Caraco to sell cetirizine hydrochloride tablets as the generic equivalent of Zyrtec Allergy Tablets and Zyrtec Hives Crain's Detroit Business, Johnson & Johnson Reports Fourth-Quarter and Full-Year 2007 Results - Jan 22, 2008 During the quarter, the Company received approval from the FDA for the allergy treatments ZYRTEC (cetirizine HCl) and ZYRTEC-D 12 HOUR (cetirizine HCl 5 PharmaLive.com (press release), Zyrtec Now Available Over The Counter - Jan 23, 2008 Zyrtec is the brand name for cetirizine and is approved to relieve allergy-related sneezing, runny nose, watery eyes, and also, itching from hives. KCRA.com, Allergy Treatment ZYRTEC(R) Now Available Without a Prescription - Jan 23, 2008 23 -- McNeil Consumer Healthcare, a division of McNEIL-PPC, Inc., announced today that ZYRTEC(R) (cetirizine HCl), the number one prescribed allergy Earthtimes, US drug giants buy up $86m Galpharm - Jan 11, 2008 ...significantly outselling other brands – while its brands of Cetirizine and Loratadine, used to treat hay fever and other allergies, are also market Huddersfield Examiner, Drug Makers Approved To Sell Zyrtec Knockoffs - Jan 8, 2008 India’s Ranbaxy Laboratories Ltd. and Iceland’s Actavis Group were among those approved to package cetirizine hydrochlorideâ€�the active ingredient NJBIZ, Perrigo Reports Record Sales and Earnings for Second Quarter ... - Feb 5, 2008 On December 28, 2007, Perrigo announced it received final approval from the FDA for its Abbreviated New Drug Application (ANDA) for OTC Cetirizine PharmaLive.com (press release), Brand Names/Synonyms: Cetirizine is also known by the following brand names and/or synonymsAlerlisin; CHEMBANK1856; Cetirizina [Spanish]; Cetirizine; Cetirizinum [Latin]; Cetrizine Hcl; Cetryn; Formistin; Hitrizin Film Tablet; Reactine; Setir; Virlix; Ziptek; Zirtek; Zyrlex; Zyrtec Drug Category: Cetirizine is categorized under the following by the FDA: Anti-allergic Agents; Antihistamines; ATC:R06AE07; ATC:R06AE09 Dosage Forms: tablets Absorption: mean peak plasma concentration (Cmax) of 114 ng/mL at a time (Tmax) of 2.2 hours postdose was observed for cetirizine Interactions: Interactions for Cetirizine: Pharmacokinetic interaction studies with cetirizine in adults were conducted with pseudoephedrine, antipyrine, ketoconazole, erythromycin and azithromycin. No interactions were observed. In a multiple dose study of theophylline (400 mg once daily for 3 days) and cetirizine (20 mg once daily for 3 days), a 16% decrease in the clearance of cetirizine was observed. The disposition of theophylline was not altered by concomitant cetirizine administration. Drug-Drug Interactions: No clinically significant drug interactions have been found with theophylline at a low dose, azithromycin, pseudoephedrine, ketoconazole, or erythromycin. There was a small decrease in the clearance of cetirizine caused by a 400-mg dose of theophylline; it is possible that larger theophylline doses could have a greater effect. Chemical IUPAC Name: 2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]aceticacid : |
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